Eight high strength concrete (HSC) prisms strengthened with continuous carbon fiber sheet(CFS)were tested.As a result of the confinement provided by CFS,the concrete would fail at a greater strain than the unconfined ...Eight high strength concrete (HSC) prisms strengthened with continuous carbon fiber sheet(CFS)were tested.As a result of the confinement provided by CFS,the concrete would fail at a greater strain than the unconfined and then a significant increase in ductility can be achieved.The lateral pressure exerted by CFS would increase the compressive strength of the concrete,resulting in higher load bearing capacity.This paper proposes the stress strain curve of this kind of hybrid specimen,which agrees well with the test results.Based on the stress strain relationship and the assumptions proposed in this paper,a computer program was developed to analyze HSC columns,confined by CFS,which were subjected to axial compression and biaxial bending.The results shown in this paper indicate that the ductility of HSC column is significantly improved and the strength is also increased by some degree.展开更多
A novel engineered cementitious composite(ECC) was prepared with the complex binder of Portland cement and asphalt emulsion.By adjusting the amount of asphalt emulsion,different mixture proportions were adopted in exp...A novel engineered cementitious composite(ECC) was prepared with the complex binder of Portland cement and asphalt emulsion.By adjusting the amount of asphalt emulsion,different mixture proportions were adopted in experiments,including four-point bending test,compressive test,and scanning electric microscopy(SEM).The SEM observation was conducted to evaluate the contribution of polyvinyl alcohol(PVA) fiber and asphalt emulsion to the composite toughening mechanism.The tests results show that the most remarkable deflection-hardening behavior and saturated multiple cracking are achieved when the content of asphalt emulsion is 10%.However,excessive content of asphalt emulsion causes severe damages on the deformation behavior as well as loss in compressive strength of the mixture.SEM observation indicates that the influence of asphalt emulsion on the fiber/matrix interfacial property changes the dominant fiber failure type from rupture into pull-out mode,and thus causes beneficial effects for strain-hardening behavior.展开更多
Congenital hepatic fibrosis (CHF) is an autosomal recessive disorder that belongs to the family of fibropolycystic liver diseases. This family includes a spectrum of disorders which are usually found in combination wi...Congenital hepatic fibrosis (CHF) is an autosomal recessive disorder that belongs to the family of fibropolycystic liver diseases. This family includes a spectrum of disorders which are usually found in combination with each other and are usually inherited. Clinically fibropolycystic diseases have three effects being present in different proportions, those of a space occupying lesion, of portal hypertension and of cholangitis. In most patients, the first manifestations of CHF are signs and symptoms related to portal hypertension such as splenomegaly and varices. Portal hypertension in these patients has been attributed to the hypoplasia or compression of the portal vein radicles in the fibrous bands. Cavernous transformation of the portal vein (CTPV) is a relatively rare condition resulting from extrahepatic portal vein obstruction with recanalization or collateral vein formation to bypass the obstruction. It has been found that patients with CHF having an accompanying CTPV have relatively large splenomegaly and suffers more frequent episodes of bleeding from esophageal varices.We believe that CTPV is a congenital component of CHF and also one of the important causative factors of portal hypertension in these patients.展开更多
To evaluate the role of tissue factor (TF) and protease activated receptor (PAR)-2 in liver fibrosis. METHODSUsing CCl<sub>4</sub> administration for eight weeks, we induced hepatic fibrosis in wild-type C...To evaluate the role of tissue factor (TF) and protease activated receptor (PAR)-2 in liver fibrosis. METHODSUsing CCl<sub>4</sub> administration for eight weeks, we induced hepatic fibrosis in wild-type C57BL/6 mice and in mice with deletion of the cytoplasmic signalling domain of TF (TF<sup>§CT/§CT</sup>), deletion of PAR-2 (PAR-2<sup>-/-</sup>) and combined deletion of TF signalling domain and PAR-2 (TF<sup>§CT/§CT</sup>/PAR-2<sup>-/-</sup>). Hepatic fibrosis area was assessed by quantitative imaging of picrosirius red staining. Hepatic collagen content was assessed by hydroxyproline levels. Hepatic stellate cells (αSMA positive) and hepatic macrophages (CD68 positive) were identified by immunohistochemistry. Hepatic gene expression was determined by PCR and liver TGFβ1 content by ELISA. RESULTSCCl<sub>4</sub> treated mice with deletion of the PAR-2 gene (PAR-2<sup>-/-</sup>) and the cytoplasmic domain of TF (TF<sup>§CT/§CT</sup>) developed significantly less hepatic fibrosis, characterised by reduced liver fibrosis area and hydroxyproline content, compared to control wildtype mice treated with CCl<sub>4</sub>. The observed reduction in histological fibrosis was accompanied by a significant decrease in the hepatic content of TGFβ, the prototypic fibrogenic cytokine, as well as fewer activated hepatic stellate cells and hepatic macrophages. Deletion of the TF cytoplasmic signalling domain reduced hepatic fibrosis to levels similar to those observed in mice lacking PAR-2 signalling but combined deletion provided no added protection against fibrosis indicating a lack of mutual modulating effects that have been observed in other contexts such as angiogenic responses. CONCLUSIONTissue factor cytoplasmic domain is involved in TF-PAR-2 signalling initiating hepatic fibrosis and is a potential therapeutic target, as its deletion would not impact coagulation.展开更多
The effect of strain and drawing temperature on the evolution of microstructure and fiber textures of aluminum wiresdrawn at room temperature and cryogenic temperature was investigated by TEM and EBSD observations.The...The effect of strain and drawing temperature on the evolution of microstructure and fiber textures of aluminum wiresdrawn at room temperature and cryogenic temperature was investigated by TEM and EBSD observations.The results show that lowangle boundaries frequency increases and high angle boundaries frequency decreases with strain increasing when the strain is low.Athigh strain,most of grain and dislocation boundaries are parallel to the drawn direction and low angle boundaries frequencydecreases and high angle boundaries frequency increases with strain increasing.The decrease of deformation temperature leads tomicrostructure finer and low angle boundaries frequency increasing.Texture analysis indicates that volume fraction of complextexture component decreases with strain increasing and a mixture of?111?and?100?fiber texture forms at high strain.?111?is stableat low strains but?100?becomes stable at high strain.The decrease of temperature can enhance the stability of?111?orientation athigh strain.展开更多
The effect of heat treatment on the structure of Poly(p-phenylene benzobisoxazole) (PBO) fiber was studied by wide angle X-ray diffraction (WAXD) and differential scanning calorimetry-(DSC), which resuits in c...The effect of heat treatment on the structure of Poly(p-phenylene benzobisoxazole) (PBO) fiber was studied by wide angle X-ray diffraction (WAXD) and differential scanning calorimetry-(DSC), which resuits in confirmation of secondary crystallization in the heat treatment process. The effect of heat treatment on the structure and morphology of PBO fiber' s surface was investigated with X-ray photoelectron spectroscopic analysis (XPS), scanning electron microscopy (SEM) and atomic force microscopy (AFM). The results show that heat treatment not only has an effect on the composition of PBO fiber's surface, but also improves the microstmcture of PBO fiber, makes fiber more regular.展开更多
A comprehensive study of yarn architecture of two-step rectangle 3D braided composites is presented. Firstly, the braided surface, the shapes of yarns and the intertwining between braider yams and axial yams are analy...A comprehensive study of yarn architecture of two-step rectangle 3D braided composites is presented. Firstly, the braided surface, the shapes of yarns and the intertwining between braider yams and axial yams are analyzed from experimentation. With the microstructure being defined, three levels of unit cell structure are identified, i.e. large unit cell, second unit cell and minimal unit cell. Secondly, based on the minimal unit cell in the interior and on the boundary of the entire cross-section, the deformations of axial yams squashed by braider yams contribute to the increase of the fiber packing factors of axial yams. Finally, the predicted fiber volume fraction of the composites decreases with the increase of linear density of the braider yam and the pitch length. Favorable correlations between the predicted and the experimental results arc found for six groups of the composites.展开更多
We demonstrate a new kind of multi-core photonic liquid crystal fibers (PLCFs) which have six liquid crystal cores arrayed in the ring-type geometry and separated by the air holes. Through analyzing the structure of t...We demonstrate a new kind of multi-core photonic liquid crystal fibers (PLCFs) which have six liquid crystal cores arrayed in the ring-type geometry and separated by the air holes. Through analyzing the structure of this kind of PLCFs, it can be found that they have the ability to resist the structure deformation. Due to the effective index of the liquid crystal can be adjusted by temperature and wavelength, the energy in the six liquid crystal cores is increased with the temperature increasing and wavelength decreasing. The effective index of the PLCFs is decreased, the effective fundamental mode area is increased and the dispersion properties are gently affected with the wavelength increasing and temperature decreasing.展开更多
文摘Eight high strength concrete (HSC) prisms strengthened with continuous carbon fiber sheet(CFS)were tested.As a result of the confinement provided by CFS,the concrete would fail at a greater strain than the unconfined and then a significant increase in ductility can be achieved.The lateral pressure exerted by CFS would increase the compressive strength of the concrete,resulting in higher load bearing capacity.This paper proposes the stress strain curve of this kind of hybrid specimen,which agrees well with the test results.Based on the stress strain relationship and the assumptions proposed in this paper,a computer program was developed to analyze HSC columns,confined by CFS,which were subjected to axial compression and biaxial bending.The results shown in this paper indicate that the ductility of HSC column is significantly improved and the strength is also increased by some degree.
基金Project(2011BAE27B04)supported by the National Key Technology R&D Program of ChinaProjects(CHD2011TD003,CHD2011ZD017)supported by the Special Fund for Basic Scientific Research of Central Colleges in Chang’an University,China
文摘A novel engineered cementitious composite(ECC) was prepared with the complex binder of Portland cement and asphalt emulsion.By adjusting the amount of asphalt emulsion,different mixture proportions were adopted in experiments,including four-point bending test,compressive test,and scanning electric microscopy(SEM).The SEM observation was conducted to evaluate the contribution of polyvinyl alcohol(PVA) fiber and asphalt emulsion to the composite toughening mechanism.The tests results show that the most remarkable deflection-hardening behavior and saturated multiple cracking are achieved when the content of asphalt emulsion is 10%.However,excessive content of asphalt emulsion causes severe damages on the deformation behavior as well as loss in compressive strength of the mixture.SEM observation indicates that the influence of asphalt emulsion on the fiber/matrix interfacial property changes the dominant fiber failure type from rupture into pull-out mode,and thus causes beneficial effects for strain-hardening behavior.
文摘Congenital hepatic fibrosis (CHF) is an autosomal recessive disorder that belongs to the family of fibropolycystic liver diseases. This family includes a spectrum of disorders which are usually found in combination with each other and are usually inherited. Clinically fibropolycystic diseases have three effects being present in different proportions, those of a space occupying lesion, of portal hypertension and of cholangitis. In most patients, the first manifestations of CHF are signs and symptoms related to portal hypertension such as splenomegaly and varices. Portal hypertension in these patients has been attributed to the hypoplasia or compression of the portal vein radicles in the fibrous bands. Cavernous transformation of the portal vein (CTPV) is a relatively rare condition resulting from extrahepatic portal vein obstruction with recanalization or collateral vein formation to bypass the obstruction. It has been found that patients with CHF having an accompanying CTPV have relatively large splenomegaly and suffers more frequent episodes of bleeding from esophageal varices.We believe that CTPV is a congenital component of CHF and also one of the important causative factors of portal hypertension in these patients.
文摘To evaluate the role of tissue factor (TF) and protease activated receptor (PAR)-2 in liver fibrosis. METHODSUsing CCl<sub>4</sub> administration for eight weeks, we induced hepatic fibrosis in wild-type C57BL/6 mice and in mice with deletion of the cytoplasmic signalling domain of TF (TF<sup>§CT/§CT</sup>), deletion of PAR-2 (PAR-2<sup>-/-</sup>) and combined deletion of TF signalling domain and PAR-2 (TF<sup>§CT/§CT</sup>/PAR-2<sup>-/-</sup>). Hepatic fibrosis area was assessed by quantitative imaging of picrosirius red staining. Hepatic collagen content was assessed by hydroxyproline levels. Hepatic stellate cells (αSMA positive) and hepatic macrophages (CD68 positive) were identified by immunohistochemistry. Hepatic gene expression was determined by PCR and liver TGFβ1 content by ELISA. RESULTSCCl<sub>4</sub> treated mice with deletion of the PAR-2 gene (PAR-2<sup>-/-</sup>) and the cytoplasmic domain of TF (TF<sup>§CT/§CT</sup>) developed significantly less hepatic fibrosis, characterised by reduced liver fibrosis area and hydroxyproline content, compared to control wildtype mice treated with CCl<sub>4</sub>. The observed reduction in histological fibrosis was accompanied by a significant decrease in the hepatic content of TGFβ, the prototypic fibrogenic cytokine, as well as fewer activated hepatic stellate cells and hepatic macrophages. Deletion of the TF cytoplasmic signalling domain reduced hepatic fibrosis to levels similar to those observed in mice lacking PAR-2 signalling but combined deletion provided no added protection against fibrosis indicating a lack of mutual modulating effects that have been observed in other contexts such as angiogenic responses. CONCLUSIONTissue factor cytoplasmic domain is involved in TF-PAR-2 signalling initiating hepatic fibrosis and is a potential therapeutic target, as its deletion would not impact coagulation.
基金Projects(51471123,51171135)supported by the National Natural Science Foundation of ChinaProjects(2012K07-08,2013KJXX-61)supported by the Natural Science Foundation of Shaanxi Province,ChinaProject(2013JC14)supported by the Industrialization Program of Shaanxi Province,China
文摘The effect of strain and drawing temperature on the evolution of microstructure and fiber textures of aluminum wiresdrawn at room temperature and cryogenic temperature was investigated by TEM and EBSD observations.The results show that lowangle boundaries frequency increases and high angle boundaries frequency decreases with strain increasing when the strain is low.Athigh strain,most of grain and dislocation boundaries are parallel to the drawn direction and low angle boundaries frequencydecreases and high angle boundaries frequency increases with strain increasing.The decrease of deformation temperature leads tomicrostructure finer and low angle boundaries frequency increasing.Texture analysis indicates that volume fraction of complextexture component decreases with strain increasing and a mixture of?111?and?100?fiber texture forms at high strain.?111?is stableat low strains but?100?becomes stable at high strain.The decrease of temperature can enhance the stability of?111?orientation athigh strain.
文摘The effect of heat treatment on the structure of Poly(p-phenylene benzobisoxazole) (PBO) fiber was studied by wide angle X-ray diffraction (WAXD) and differential scanning calorimetry-(DSC), which resuits in confirmation of secondary crystallization in the heat treatment process. The effect of heat treatment on the structure and morphology of PBO fiber' s surface was investigated with X-ray photoelectron spectroscopic analysis (XPS), scanning electron microscopy (SEM) and atomic force microscopy (AFM). The results show that heat treatment not only has an effect on the composition of PBO fiber's surface, but also improves the microstmcture of PBO fiber, makes fiber more regular.
基金This research was funded by Scientific Research Fund of National Ministry of Education (00135)
文摘A comprehensive study of yarn architecture of two-step rectangle 3D braided composites is presented. Firstly, the braided surface, the shapes of yarns and the intertwining between braider yams and axial yams are analyzed from experimentation. With the microstructure being defined, three levels of unit cell structure are identified, i.e. large unit cell, second unit cell and minimal unit cell. Secondly, based on the minimal unit cell in the interior and on the boundary of the entire cross-section, the deformations of axial yams squashed by braider yams contribute to the increase of the fiber packing factors of axial yams. Finally, the predicted fiber volume fraction of the composites decreases with the increase of linear density of the braider yam and the pitch length. Favorable correlations between the predicted and the experimental results arc found for six groups of the composites.
基金supported by the National Natural Science Foundation of China (Nos.61077047 and 61107059)the Natural Science Foundation of Heilongjiang Province (No.A200914)the Research Fund for the Doctoral Program of Higher Education of China (No.200802171034)
文摘We demonstrate a new kind of multi-core photonic liquid crystal fibers (PLCFs) which have six liquid crystal cores arrayed in the ring-type geometry and separated by the air holes. Through analyzing the structure of this kind of PLCFs, it can be found that they have the ability to resist the structure deformation. Due to the effective index of the liquid crystal can be adjusted by temperature and wavelength, the energy in the six liquid crystal cores is increased with the temperature increasing and wavelength decreasing. The effective index of the PLCFs is decreased, the effective fundamental mode area is increased and the dispersion properties are gently affected with the wavelength increasing and temperature decreasing.