南盘江坳陷北缘中泥盆统纳标组页岩气地质特征与勘探潜力

通过大量野外露头、钻井岩心资料,以南盘江坳陷北缘中泥盆统纳标组泥页岩为研究对象,借助有机地化、物性、氩离子抛光+扫描电子显微镜检测、X-衍射、等温吸附等分析测试手段,系统开展了页岩气成藏条件研究。结果表明:南盘江坳陷北缘纳标组优质泥页岩以深水陆棚泥页岩为主,厚度20-100m,TOC平均3.17%,有机质类型Ⅱ1型,Ro2.07-3.49%,孔隙度平均2.84%,有机质孔隙发育,脆性矿物含量平均48%,平均吸附气量2.86m3/t;区内发育良好的区域盖层和顶底板条件,构造变形较弱,保存条件较好。结论认为,南盘江坳陷北缘具有良好的页岩气勘探前景,宽缓的向斜区是页岩气勘探有利区,纳标组泥页岩是勘探的重点层段。

桂中坳陷中泥盆统纳标组层序地层与岩相古地理研究

综合运用露头、岩心、层序地层学和沉积学的理论方法,对桂中坳陷中泥盆统纳标组的露头和钻井资料进行了详细地分析研究,共识别出3个三级层序,从下到上依次为SQ1、SQ2、SQ3;同时对坳陷内中泥盆统地层层序界面的类型和界面的特征进行了重点分析,认为区内的层序界面主要包括古风化壳、大气淡水作用面、岩性、岩相转化面和上超面。通过对基干剖面、辅助剖面和主要的钻井资料的分析,对研究区的沉积体系有了较为全面的认识,结合露头和钻井资料,对桂中坳陷中泥盆纪应堂期的岩相古地理进行了详细地分析,编制了桂中坳陷中泥盆纪应堂组期(SQ1,SQ2,SQ3)的岩相古地理图。

纳标与清标的概念及其内在联系的探讨

纳标与清标的概念及其内在联系的探讨保定工务段王飞飞在纳标问题上，一些站段为了提高标准的复盖率，存在着盲目纳标的倾向。在没有经过很好斟酌的情况下，就把某些甚至是所有的规章、文件、办法等突击强行纳标。有的为了省事，干脆采用“包装法”，只在规章、办法的前面...

LY12MCS状态板材热处理制度及力学性能指标的确定

本文概述了LY12合金的基本特性,提出了对LY12MCS状态力性能的要求,并通过工业性试验和对比分析,确定了LY12MCS的热处理制度及力学性能指标,为纳标和选材提供了可靠依据,对生产和使用有指导性意义.

Improvement of hybridization signals of gold label silver stain gene detection

The factors that influence the colorimetric gene detection of gold label silver stain and improve the detection signals were studied. The influence of amino DNA probes and thiol DNA modified gold nanoparticles was investigated based on a sandwich hybridization system. An increase in amino probe concentration brought about an increase in hybridization signal which reached a threshold corresponding to the saturated concentration of amino probes bounded onto a glass slide surface. Since the steric hindrance effect of nanoparticles was dominant over the influence of a surface area, the bigger gold nanoparticles led to weaker hybridization signals. The hybridization efficiency enhanced significantly with the increase of the thiol DNA modified nanoparticle concentrations. Experimental results showed that 125 μmol/L of the amino DNA probe concentration, 15 nm of the gold nanoparticle diameter, and 4.07 nmol/L of the thiol DNA modified gold nanoparticle concentration were optimal for the detection system. The hybridization signals can be improved remarkably by choosing optimal hybridization conditions.

物业管理合同的质量问题

在新型的物业管理体制下,业主或业主委员会须跟物业管理企业签订物业管理合同。合同一经签订,就具有法律效力,双方必须全面履约。实际上,履约的过程就是减少或控制对方索赔的过程。因此,物业管理合同的质量主要指以下两个方面:一是合同的签约质量,二是合同的覆约质量。

Liver histology according to the presence of metabolic syndrome in nonalcoholic fatty liver disease cases

AIM:To investigate the histologic features of the liver in nonalcoholic fatty liver disease (NAFLD) cases according to the presence of metabolic syndrome or its individual components. METHODS:We enrolled 81 patients (40 male,41 fe-male) who were diagnosed with fatty liver by ultraso-nographic scan and fulfi lled the inclusion criteria. First anamnesis,anthropometric,clinical,laboratory and imaging features of all participants were recorded and then liver biopsy was performed after gaining consent from patients. Diagnosis of metabolic syndrome was dependent on patients having 3 or more out of 5 risk criteria defined by the WHO. Biopsy specimens were assessed according to Brunt et al's classification. RESULTS:Sixty-nine of the 81 patients had nonalco-holic steatohepatitis (NASH),11 had simple fatty liver and 1 had cirrhosis according to histologic evaluation. Comparisons were made between two groups of NASH patients,those with and without metabolic syndrome. We did not detect statistically significant differences in liver histology between NASH patients with and wit-hout metabolic syndrome. CONCLUSION:NASH can progress without metabolic risk factors or the presence of metabolic syndrome.

Study on fast calibration of a ULA's gain and phase error

Array calibration is important in engineering practice. In this paper, fast calibration methods for a ULA's gain and phase errors both in far and near fields are proposed. In the far field, using a single sound source without exact orientation, this method horizontally rotates the array exactly once, performs eigen value decomposition for the covariance matrix of received data, then computes the gain and phase error according to the formulas. In the near field, using the same single sound source, it is necessary to rotate the array horizontally at most three times, build equations according to geometric relations, then solve them. Using the formula proposed in this paper, spherical waves are modified into plane waves. Then eigen values decomposition is performed. These two calibration methods were shown to be valid by simulation and are fast, accurate and easy to use. Finally, an analysis of factors influencing estimation precision is given.

Analysis of Genetic Diversity and Differentiation of Seven Stocks of Litopenaeus vannamei Using Microsatellite Markers

Seven microsatellite markers were used to evaluate the genetic diversity and differentiation of seven stocks of Litopenaeus vannamei, which were introduced from Central and South America to China. All seven microsatellite loci were polymorphic, with polymorphism information content(PIC) values ranging from 0.593 to 0.952. Totally 92 alleles were identified, and the number of alleles(Na) and effective alleles(Ne) varied between 4 and 21 and 2.7 and 14.6, respectively. Observed heterozygosity(Ho) values were lower than the expected heterozygosity(He) values(0.526–0.754), which indicated that the seven stocks possessed a rich genetic diversity. Thirty-seven tests were detected for reasonable significant deviation from Hardy-Weinberg equilibrium. Fis values were positive at five loci, suggesting that there was a relatively high degree of inbreeding within stocks. Pairwise Fst values ranged from 0.0225 to 0.151, and most of the stock pairs were moderately differentiated. Genetic distance and cluster analysis using UPGMA revealed a close genetic relationship of L. vannamei between Pop2 and Pop3. AMOVA indicated that the genetic variation among stocks(11.3%) was much lower than that within stocks(88.7%). Although the seven stocks had a certain degree of genetic differentiation and a rich genetic diversity, there is an increasing risk of decreased performance due to inbreeding in subsequent generations.

Goal-Setting in the Information-Generating Environment of the Universe

Problem of goal-setting is related to the fundamental principles of informationology and general, rather than specific, aproaches, which enable a more adequate appraisal of certain managerial decisions in terms of their efficiency. In article this problem is considered and from positions of informationology is formulated and on the basis of a method of full mathematical induction the Law of positive dynamics of the Universe is proved. This law establishes preference of the positive purposes in all processes happening in the Universe. Thus, the goal-setting which is carried out from positions of the described Law is the important world outlook prerequisite searching, identification and development of strategic alternatives of purposeful social innovations.

Human induced pluripotent stem cells labeled with fluorescent magnetic nanoparticles for targeted imaging and hyperthermia therapy for gastric cancer

Objective: Human induced pluripotent stem(i PS) cells exhibit great potential for generating functional human cells for medical therapies. In this paper, we report for use of human i PS cells labeled with fluorescent magnetic nanoparticles(FMNPs) for targeted imaging and synergistic therapy of gastric cancer cells in vivo. Methods: Human i PS cells were prepared and cultured for 72 h. The culture medium was collected, and then was coincubated with MGC803 cells. Cell viability was analyzed by the MTT method. FMNP-labeled human i PS cells were prepared and injected into gastric cancer-bearing nude mice. The mouse model was observed using a small-animal imaging system. The nude mice were irradiated under an external alternating magnetic field and evaluated using an infrared thermal mapping instrument. Tumor sizes were measured weekly. Results: iP S cells and the collected culture medium inhibited the growth of MGC803 cells. FMNP-labeled human iP S cells targeted and imaged gastric cancer cells in vivo, as well as inhibited cancer growth in vivo through the external magnetic field. Conclusion: FMNP-labeled human i PS cells exhibit considerable potential in applications such as targeted dual-mode imaging and synergistic therapy for early gastric cancer.

Design of Sustainable Multifunctional Nanocoatings：A Goal-driven Multiscale Systems Approach

Polymer nanocomposites have a great potential to be a dominant coating material in a wide range of applications in the automotive,aerospace,ship-making,construction,and pharmaceutical industries.However,how to realize design sustainability of this type of nanostructured materials and how to ensure the true optimality of the product quality and process performance in coating manufacturing remain as a mountaintop area.The major challenges arise from the intrinsic multiscale nature of the material-process-product system and the need to manipulate the high levels of complexity and uncertainty in design and manufacturing processes.In this work,the challenging objectives of sustainable design and manufacturing are simultaneously accomplished by resorting to multiscale systems theory and engineering sustainability principles.The principal idea is to achieve exceptional system performance through concurrent characterization and optimization of materials,product and associated manufacturing processes covering a wide range of length and time scales.Multiscale modeling and simulation techniques ranging from microscopic molecular modeling to classical continuum modeling are seamlessly coupled.The integration of different methods and theories at individual scales allows the quantitative prediction of macroscopic system performance from the fundamental molecular behavior.Furthermore,mathematically rigorous and methodologically viable approaches are pursued to achieve sustainability-goal-oriented design of material-process-product systems.The introduced methodology can greatly facilitate experimentalists in novel material invention and new knowledge discovery.At the same time,it can provide scientific guidance and reveal various new opportunities and effective strategies for achieving sustainable manufacturing.The methodological attractiveness will be fully demonstrated by a detailed case study on the design of thermoset nanocomposite coatings.

Potential Use of Crushed Ghanaian Limestone in Paste and Mortar Formulated for Masonry

Crushed Ghanaian limestone （L） powder was analysed for its physical, chemical and microstructural properties for the formulation of mortar for masonry. Ordinary Portland Cement （OPC） was replaced by 10- 40% limestone powder for paste and mortar formulation. Mechanical properties that included compressive strength, water demand and setting times （initial and final） were determined and analysed. The mechanical properties were determined in accordance with ASTM standards. The test results indicated that crushed limestone powder contained about 88.7% CaO in calcite form. A 10-30% and 35-40% limestone content in conjunction with OPC was suitable to produce ASTM type M and S mortars respectively. Formulated OPC - L paste showed a high water demand, a delayed initial setting time and an accelerated final setting time than the plain OPC paste.

Molecular markers for identifying a new selected variety of Pacific white shrimp Litopenaeus vannamei

Selective breeding of the Pacific white shrimp Litopenaeus vannamei during the last decade has produced new varieties exhibiting high growth rates and disease resistance.However,the identification of new varieties of shrimps from their phenotypic characters is difficult.This study introduces a new approach for identifying varieties of shrimps using molecular markers of microsatellites and mitochondrial control region sequences.The method was employed to identify a new selected variety,Kehai No.1(KH-1),from three representative stocks(control group):Zhengda;Tongwei;and a stock collected from Fujian Province,which is now cultured in China's Mainland.By pooled genotyping of KH-1 and the control group,five microsatellites showing differences between KH-1 and the control group were screened out.Individual genotyping data confirmed the results from pooled genotyping.The genotyping data for the five microsatellites were applied to the assignment analysis of the KH-1 group and the control group using the partial Bayesian assignment method in GENECLASS2.By sequencing the mitochondrial control regions of individuals from the KH-1 and control group,four haplotypes were observed in the KH-1 group,whereas14 haplotypes were obtained in the control group.By combining the microsatellite assignment analysis with mitochondrial control region analysis,the average accuracy of identification of individuals in the KH-1group and control group reached 89%.The five selected microsatellite loci and mitochondrial control region sequences were highly polymorphic and could be used to distinguish new selected varieties of L.vannamei from other populations cultured in China.

Optimal design of functionally graded Pm PV/CNT nanocomposite cylindrical tube for purpose of torque transmission

Carbon nanotube(CNT)/polymer nanocomposites have vast application in industry because of their light mass and high strength. In this work, a cylindrical tube which is made up of functionally graded(FG) PmP V/CNT nanocomposite, is optimally designed for the purpose of torque transmission. The main confining parameters of a rotating shaft in torque transmission process are mass of the shaft, critical speed of rotation and critical buckling torque. It is required to solve a multi-objective optimization problem(MOP) to consider these three targets simultaneously in the process of design. The three-objective optimization problem for this case is defined and solved using a hybrid method of FEM and modified non-dominated sorting genetic algorithm(NSGA-II), by coupling two softwares, MATLAB and ABAQUS. Optimization process provides a set of non-dominated optimal design vectors. Then, two methods, nearest to ideal point(NIP) and technique for ordering preferences by similarity to ideal solution(TOPSIS), are employed to choose trade-off optimum design vectors. Optimum parameters that are obtained from this work are compared with the results of previous studies for similar cylindrical tubes made from composite or a hybrid of aluminum and composite that more than 20% improvement is observed in all of the objective functions.

Underwater sonar target imaging via compressed sensing with M sequences

Due to the low sound propagation speed, the tradeoff between high azimuth resolution and wide imaging swath has severely limited the application of sonar underwater target imaging. However, based on compressed sensing(CS) technique, it is feasible to image targets with merely one pulse and thus avoid the above tradeoff. To investigate the possible waveforms for CS-based underwater imaging, the deterministic M sequences widely used in sonar applications are introduced in this paper. By analyzing the compressive matrix constructed from M sequences, the coherence parameter and the restricted isometry property(RIP) of the matrix are derived. Also, the feasibility and advances of M sequence are demonstrated by being compared with the existing Alltop sequence in underwater CS imaging framework. Finally, the results of numerical simulations and a real experiment are provided to reveal the effectiveness of the proposed signal.

Transparent paper-based triboelectric nanogenerator as a page mark and anti-theft sensor

The triboelectric nanogenerator （TENG）, based on the well-known triboelectric effect and electrostatic induction effect, has been proven to be a simple, cost effective approach for self-powered systems to convert ambient mechanical energy into electricity. We report a flexible and transparent paper-based triboelectric nanogenerator （PTENG） consisting of an indium tin oxide （ITO） film and a polyethylene terephthalate （PET） film as the triboelectric surfaces, which not only acts as an energy supply but also as a self-powered active sensor. It can harvest kinetic energy when the sheets of paper come into contact, bend or slide relative to one another by a combination of vertical contact-separation mode and lateral sliding mode. In addition, we also integrate grating-structured PTENGs into a book as a self-powered anti-theft sensor. The mechanical agitation during handling the book pages can be effectively converted into an electrical output to either drive a commercial electronic device or trigger a warning buzzer. Furthermore, different grating-structures on each page produce different numbers of output peaks by sliding relative to one another, which can accurately act as a page mark and record the number of pages turned. This work is a significant step forward in self-powered paper-based devices.

Nonzero-sum games for continuous-time Markov chains with unbounded transition and average payoff rates

This paper attempts to study two-person nonzero-sum games for denumerable continuous-time Markov chains determined by transition rates,with an expected average criterion.The transition rates are allowed to be unbounded,and the payoff functions may be unbounded from above and from below.We give suitable conditions under which the existence of a Nash equilibrium is ensured.More precisely,using the socalled "vanishing discount" approach,a Nash equilibrium for the average criterion is obtained as a limit point of a sequence of equilibrium strategies for the discounted criterion as the discount factors tend to zero.Our results are illustrated with a birth-and-death game.

A label-free colorimetric assay for detection of c-Myc mRNA based on peptide nucleic acid and silver nanoparticles

A label-free colorimetric protocol based on peptide nucleic acid/silver nanoparticles(PNA/Ag NPs) has been initially proposed for specific recognition of m RNA.Making use of the controlled silver nanoparticles aggregation/dispersion by PNA/PNA–RNA complex, proto-oncogene c-Myc m RNA detection can be achieved. Moreover, the PNA/Ag NPs platform can undergo color change in response to target c-Myc m RNA with single-base-mismatch sensitivity, which could further help in visually identify single nucleotide differences in target genes.

Complete thermoelectric benchmarking of individual InSb nanowires using combined micro-Raman and electric transport analysis

Nanowires （NWs） are ideal nanostructures for exploring the effects of low dimensionality and thermal conductivity suppression on thermoelectric behavior. However, it is challenging to accurately measure temperature gradients and heat flow in such systems. Here, using a combination of spatially resolved Raman spectroscopy and transport measurements, we determine all the thermoelectric properties of single Se-doped InSb NWs and quantify the figure of merit ZT. The measured laser-induced heating in the NWs and associated electrical response are well described by a 1D heat equation model. Our method allows the determination of the thermal contact resistances at the source and drain electrodes of the NW, which are negligible in our system. The measured thermoelectric parameters of InSb NWs agree well with those obtained based on field-effect transistor Seebeck measurements.