[Objective] The experiment aimed to explore release rule of water-soluble chitosan (WSC) in vitro. [Method]The bovine serum albumin(BSA) was taken as a model protein drug and some existing release models such as Kinet...[Objective] The experiment aimed to explore release rule of water-soluble chitosan (WSC) in vitro. [Method]The bovine serum albumin(BSA) was taken as a model protein drug and some existing release models such as Kinetics model, Gompertz model, Weibull model, Higuchi model and Logistic model were used to fit the BSA release profile from WSC carriers. [Result] Except Higuchi model and Logistic model, other models could fit BSA release profile better. [Conclusion] Gompertz two-order kinetics model could fit the release of WSC nano-particles better and model parameters had practical physical meaning.展开更多
A new approach,gate-capacitance-shift (GCS) approach,is described for compact modeling.This approach is piecewise for various physical effects and comprises the gate-bias-dependent nature of corrections in the nanosca...A new approach,gate-capacitance-shift (GCS) approach,is described for compact modeling.This approach is piecewise for various physical effects and comprises the gate-bias-dependent nature of corrections in the nanoscale regime.Additionally,an approximate-analytical solution to the quantum mechanical (QM) effects in polysilicon (poly)-gates is obtained based on the density gradient model.It is then combined with the GCS approach to develop a compact model for these effects.The model results tally well with numerical simulation.Both the model results and simulation results indicate that the QM effects in poly-gates of nanoscale MOSFETs are non-negligible and have an opposite influence on the device characteristics as the poly-depletion (PD) effects do.展开更多
Zn O nanowire films were produced at 90°C using a hydrothermal chemical deposition method,and were characterised with scanning electron microscopy,optical transmission spectrometry and X-ray diffraction.The resul...Zn O nanowire films were produced at 90°C using a hydrothermal chemical deposition method,and were characterised with scanning electron microscopy,optical transmission spectrometry and X-ray diffraction.The results showed that the optical band gap is 3.274-3.347 e V.Film porosity and microstructure can be controlled by adjusting the p H of the growth solution.Zn O nanowire films comprise a 2-layer structure as demonstrated by SEM analysis,showing different porosities for each layer.XRD analysis shows preferential growth in the(002)orientation.A comprehensive optical modelling method for nanostructured Zn O thin films was proposed,consisting of Bruggeman effective medium approximations,rough surface light scattering and O’Leary-Johnson-Lim models.Fitted optical transmission of nanostructured Zn O films agreed well with experimental data.展开更多
基金Supported by the National Natural Science Foundation of China(20776054)~~
文摘[Objective] The experiment aimed to explore release rule of water-soluble chitosan (WSC) in vitro. [Method]The bovine serum albumin(BSA) was taken as a model protein drug and some existing release models such as Kinetics model, Gompertz model, Weibull model, Higuchi model and Logistic model were used to fit the BSA release profile from WSC carriers. [Result] Except Higuchi model and Logistic model, other models could fit BSA release profile better. [Conclusion] Gompertz two-order kinetics model could fit the release of WSC nano-particles better and model parameters had practical physical meaning.
文摘A new approach,gate-capacitance-shift (GCS) approach,is described for compact modeling.This approach is piecewise for various physical effects and comprises the gate-bias-dependent nature of corrections in the nanoscale regime.Additionally,an approximate-analytical solution to the quantum mechanical (QM) effects in polysilicon (poly)-gates is obtained based on the density gradient model.It is then combined with the GCS approach to develop a compact model for these effects.The model results tally well with numerical simulation.Both the model results and simulation results indicate that the QM effects in poly-gates of nanoscale MOSFETs are non-negligible and have an opposite influence on the device characteristics as the poly-depletion (PD) effects do.
文摘Zn O nanowire films were produced at 90°C using a hydrothermal chemical deposition method,and were characterised with scanning electron microscopy,optical transmission spectrometry and X-ray diffraction.The results showed that the optical band gap is 3.274-3.347 e V.Film porosity and microstructure can be controlled by adjusting the p H of the growth solution.Zn O nanowire films comprise a 2-layer structure as demonstrated by SEM analysis,showing different porosities for each layer.XRD analysis shows preferential growth in the(002)orientation.A comprehensive optical modelling method for nanostructured Zn O thin films was proposed,consisting of Bruggeman effective medium approximations,rough surface light scattering and O’Leary-Johnson-Lim models.Fitted optical transmission of nanostructured Zn O films agreed well with experimental data.