The applicability of a gold nanoparticle-modified glassy carbon sensor （AuNPs-GCS） for the determination of inorganic mercury in fresh and canned tuna fish by square wave anodic stripping voltammetry （SW-ASV） is d...The applicability of a gold nanoparticle-modified glassy carbon sensor （AuNPs-GCS） for the determination of inorganic mercury in fresh and canned tuna fish by square wave anodic stripping voltammetry （SW-ASV） is demonstrated. Mercury content in sample Tuna Fish ISPRA T22 was determined to value the accuracy of the determination. The concentration in this sample is not certified, so, the Hg amount was determined also with atomic absorption spectroscopy （AAS）： the results obtained with ASV were in good agreement and confirmed literature value reported for this sample. Then, real samples of tuna fish were analyzed. The voltammetric analyses were performed using previously optimized conditions （deposition potential 0 V, step potential 0.004 V, frequency 150 Hz and amplitude 0.003 V）. Medium exchange technique permitted to eliminate possible matrix effects. The concentrations in the real samples were found to be in agreement with the common Hg levels reported in literature for commercialized tuna fish in different countries.展开更多
Engineering nano-materials & their impact on human health or environmental security constitute a newly emerging R&D hot spot and a key problem now urgently waiting for its solution in supporting the sustainabi...Engineering nano-materials & their impact on human health or environmental security constitute a newly emerging R&D hot spot and a key problem now urgently waiting for its solution in supporting the sustainability of China's nano-science and related technology development. At present, water bodies in Chinese cities have been seriously polluted by metallic nano-particles (MNPs) while related monitoring data are found woefully lacking throughout the country. Based on the above understanding, this article gives a round-up explanation on distributive characteristics of MNPs in the river mouths or water bodies of Chinese cities, their ecological hazards as well as our research in this regard, providing some inspiring ideas and data for control over this scourge. In addition, our exploration probes the discharge traits of MNPs themselves and the mechanism underlying its impact on water pollution.展开更多
Herein, a multiwalled carbon nanotubes(MWNT)-based colorimetric probe was designed to discover and monitor the level of apolipoprotein-L1(Apo L1) in lumbar disc herniation(LDH) patients. Apo L1 could be easily found i...Herein, a multiwalled carbon nanotubes(MWNT)-based colorimetric probe was designed to discover and monitor the level of apolipoprotein-L1(Apo L1) in lumbar disc herniation(LDH) patients. Apo L1 could be easily found in human serum of the LDH group, but not obviously expressed in the normal control group(Ctrl), spine spondylolisthesis(SSP) group, spinal fracture(SFR) group, and spine scoliosis(SSC) group. Furthermore, the as-prepared MWNT-based probe was also used to track the recovery of LDH patients who have successful surgery operation. The P value of early diagnosis and recovery monitoring was <0.001 and >0.05 for the proposed method and a conventional enzyme-linked immunosorbent assay(ELISA), respectively, suggesting this detection strategy had significant differences compared with the traditional ELISA. All experimental results showed that Apo L1 might be a potential biomarker for early diagnosis of LDH. This proposed detection strategy has a potential application in discovering new biomarkers of diseases.展开更多
文摘The applicability of a gold nanoparticle-modified glassy carbon sensor （AuNPs-GCS） for the determination of inorganic mercury in fresh and canned tuna fish by square wave anodic stripping voltammetry （SW-ASV） is demonstrated. Mercury content in sample Tuna Fish ISPRA T22 was determined to value the accuracy of the determination. The concentration in this sample is not certified, so, the Hg amount was determined also with atomic absorption spectroscopy （AAS）： the results obtained with ASV were in good agreement and confirmed literature value reported for this sample. Then, real samples of tuna fish were analyzed. The voltammetric analyses were performed using previously optimized conditions （deposition potential 0 V, step potential 0.004 V, frequency 150 Hz and amplitude 0.003 V）. Medium exchange technique permitted to eliminate possible matrix effects. The concentrations in the real samples were found to be in agreement with the common Hg levels reported in literature for commercialized tuna fish in different countries.
文摘Engineering nano-materials & their impact on human health or environmental security constitute a newly emerging R&D hot spot and a key problem now urgently waiting for its solution in supporting the sustainability of China's nano-science and related technology development. At present, water bodies in Chinese cities have been seriously polluted by metallic nano-particles (MNPs) while related monitoring data are found woefully lacking throughout the country. Based on the above understanding, this article gives a round-up explanation on distributive characteristics of MNPs in the river mouths or water bodies of Chinese cities, their ecological hazards as well as our research in this regard, providing some inspiring ideas and data for control over this scourge. In addition, our exploration probes the discharge traits of MNPs themselves and the mechanism underlying its impact on water pollution.
基金supported by the National Basic Research Program of China(2012CB933301)the Key Discipline Construction Project of Pudong Health Bureau of Shanghai(PWZx2014-02)+1 种基金the Sci-tech Support Plan of Jiangsu Province(BE2014719)the Priority Academic Program Development of Jiangsu Higher Education Institutions
文摘Herein, a multiwalled carbon nanotubes(MWNT)-based colorimetric probe was designed to discover and monitor the level of apolipoprotein-L1(Apo L1) in lumbar disc herniation(LDH) patients. Apo L1 could be easily found in human serum of the LDH group, but not obviously expressed in the normal control group(Ctrl), spine spondylolisthesis(SSP) group, spinal fracture(SFR) group, and spine scoliosis(SSC) group. Furthermore, the as-prepared MWNT-based probe was also used to track the recovery of LDH patients who have successful surgery operation. The P value of early diagnosis and recovery monitoring was <0.001 and >0.05 for the proposed method and a conventional enzyme-linked immunosorbent assay(ELISA), respectively, suggesting this detection strategy had significant differences compared with the traditional ELISA. All experimental results showed that Apo L1 might be a potential biomarker for early diagnosis of LDH. This proposed detection strategy has a potential application in discovering new biomarkers of diseases.
