目的评价不同纳米过滤系统对静注人免疫球蛋白(Intravenous human immunoglobulin,IVIG)的过滤效果,以筛选最佳纳米过滤系统。方法采用不同纳米过滤器进行IVIG过滤,确定最佳纳米过滤器;选用不同预过滤器和优选的纳米过滤器组合,进行IVI...目的评价不同纳米过滤系统对静注人免疫球蛋白(Intravenous human immunoglobulin,IVIG)的过滤效果,以筛选最佳纳米过滤系统。方法采用不同纳米过滤器进行IVIG过滤,确定最佳纳米过滤器;选用不同预过滤器和优选的纳米过滤器组合,进行IVIG过滤,确定最佳纳米过滤系统。结果切向流(错流)纳米过滤器过滤效果优于死端(直流)纳米过滤器,纳米过滤器C为最佳纳米过滤器;深层过滤预过滤器的过滤效果优于绝对过滤预过滤器,预过滤器Y1串联纳米过滤器C为最佳纳米过滤系统。结论通过不同纳米过滤系统对IVIG过滤效果的评价,筛选出了最佳纳米过滤系统。展开更多
Nanofiltration separation has become a popular technique for removing large organic molecules and inorganic substances from water. It is achieved by a combination of three mechanisms: electrostatic repulsion,sieving a...Nanofiltration separation has become a popular technique for removing large organic molecules and inorganic substances from water. It is achieved by a combination of three mechanisms: electrostatic repulsion,sieving and diffusion. In the present work, a model based on irreversible thermodynamics is extended and used to estimate rejection of inorganic salts and organic substances. Binary systems are modeled, where the feed contains an ion that is much less permeable to the membrane as compared with the other ion. The two model parameters are estimated by fitting the model to the experimental data. Variation of these parameters with the composition of the feed is described by an empirical correlation. This work attempts to describe transport through the nanofiltration membranes bv a simple model.展开更多
文摘目的评价不同纳米过滤系统对静注人免疫球蛋白(Intravenous human immunoglobulin,IVIG)的过滤效果,以筛选最佳纳米过滤系统。方法采用不同纳米过滤器进行IVIG过滤,确定最佳纳米过滤器;选用不同预过滤器和优选的纳米过滤器组合,进行IVIG过滤,确定最佳纳米过滤系统。结果切向流(错流)纳米过滤器过滤效果优于死端(直流)纳米过滤器,纳米过滤器C为最佳纳米过滤器;深层过滤预过滤器的过滤效果优于绝对过滤预过滤器,预过滤器Y1串联纳米过滤器C为最佳纳米过滤系统。结论通过不同纳米过滤系统对IVIG过滤效果的评价,筛选出了最佳纳米过滤系统。
文摘Nanofiltration separation has become a popular technique for removing large organic molecules and inorganic substances from water. It is achieved by a combination of three mechanisms: electrostatic repulsion,sieving and diffusion. In the present work, a model based on irreversible thermodynamics is extended and used to estimate rejection of inorganic salts and organic substances. Binary systems are modeled, where the feed contains an ion that is much less permeable to the membrane as compared with the other ion. The two model parameters are estimated by fitting the model to the experimental data. Variation of these parameters with the composition of the feed is described by an empirical correlation. This work attempts to describe transport through the nanofiltration membranes bv a simple model.
基金Acknowledgments： This work was financially supported by Science and Technology Support Plan of The Ministry of Science and Technology of People＇s Republic of China （No. 2006BAC02A19） China National Natural Science Foundation with Grant （No. 20177014）.
