In the present paper, the authors make a simple comment on the influence of the theory of five elements of TCM on the acupuncturology from ① its influence on the meridian-collateral theory and acupoint system; ② its...In the present paper, the authors make a simple comment on the influence of the theory of five elements of TCM on the acupuncturology from ① its influence on the meridian-collateral theory and acupoint system; ② its influence on acu-moxibustion therapeutics including the application of mother and son points for reinforcing and reducing, the application of the five element theory to the midnight-noon ebb-flow needling, and guiding point selection in different seasons; and ③ its influence on acupuncture techniques.展开更多
Objective:To observe the effect of acupuncture on the expression of mitochondrial proteome in hippocampus of senescence-accelerated mouse prone g (SAMPg) mice models with Alzheimer disease (AD),and to explore the...Objective:To observe the effect of acupuncture on the expression of mitochondrial proteome in hippocampus of senescence-accelerated mouse prone g (SAMPg) mice models with Alzheimer disease (AD),and to explore the possible protective mechanism of acupuncture on mitochondria.Methods:Sixty 6-month-old male SAMP8 mice were randomly divided into an acupuncture at acupoint group,an acupuncture at non-acupoint group and a model group,20 mice in each group.The 20 male senescence-accelerated mouse/resistance 1 (SAMR1) mice of the same age were used as a normal control group.Shenshu (BL 23),Baihui (GV 20),Xuehai (SP 10) and Geshu (BL 17) were selected for acupuncture intervention in acupuncture at acupoint group.After an 8-week intervention,mitochondrial tissues were extracted from the hippocampus.Differentially expressed proteins were identified by subcellular organelle proteomics.Western blot was used to verify the expressions of some related proteins in hippocampal mitochondria.Results:Compared with the model group,there were 13 differentially expressed protein spots in the acupuncture at acupoint group,of which,9 were up-regulated,including neurofilament light polypeptide (NFL),actin (cytoplasmic 1,database ID:ACTB),tubulin beta-2A chain (TBB2A),tropomodulin-2 (TMOD2),pyruvate dehydrogenase E1 component subunit beta (PDHE1-β),NADH-ubiquinone oxidoreductase 75 kDa subunit (database ID:NDUS1),heat shock cognate 71 kDa protein (HSC71),pyruvate dehydrogenase E1 component subunit alpha (PDHE1-α) and ATP synthase beta subunit (ATP-β);4 were down-regulated,including glial fibrillary acidic protein (GFAP),pyruvate dehydrogenase phosphatase 1 (PDP1),mitochondrial-processing peptidase subunit alpha (MMP-α) and adenosine kinase (ADK).According to the information provided in the protein database,most of the differentially expressed proteins involve the regulation of mitochondrial function and structure.The expression levels of NFL and TBB2A in the normal control group and the acupuncture at acupoint group were significantly higher than those in the acupuncture at non-acupoint group (P〈0.05).ATP-β and NDUS1 expression levels were significantly higher in the acupuncture at acupoint group than those in the acupuncture at non-acupoint group (P〈0.05);there was no significant difference between the acupuncture at non-acupoint group and the model group (P〉0.05).Conclusion:Acupuncture may achieve the potential therapeutic effect on AD by regulating the structure and functional proteins of hippocampal mitochondria.展开更多
Objective: To observe the clinical effect of thread-embedding therapy in treating insomnia due to heart-spleen deficiency. Methods: Sixty patients were randomized into an acupuncture group and a thread-embedding gro...Objective: To observe the clinical effect of thread-embedding therapy in treating insomnia due to heart-spleen deficiency. Methods: Sixty patients were randomized into an acupuncture group and a thread-embedding group, 30 in each. The acupuncture group was managed by acupuncture therapy, and the thread-embedding group was treated by thread-embedding therapy. Pittsburgh Sleep Quality Index (PSQI) was adopted for evaluation before and after treatments. Results: The total effective rate was 86.7% in the acupuncture group versus 96.7% in the thread-embedding group. After treatment, the PSQI scores were significantly different from those before treatment in both groups (P〈0.01); the scores in both two groups were mai'kedly different from each other after treatment (P〈0.01). Conclusion: Both acupuncture and thread-embedding therapies can effectively improve sleep quality of the patients, while thread-embedding therapy is comparatively less time-consuming, more convenient and with longer stimulation.展开更多
Objective To explore the clinical efficacy of muscle regions of meridians needling method for refractory facial paralysis affecting different locations.Methods A total of 110 participants were randomized into an obser...Objective To explore the clinical efficacy of muscle regions of meridians needling method for refractory facial paralysis affecting different locations.Methods A total of 110 participants were randomized into an observation group and a control group,with 55 cases in each group.The observation group was treated with muscle regions of meridians needling method,and the control group was treated with conventional facial three-line needling method.The clinical efficacy was evaluated four weeks after the treatment.And the infrared imaging spectra of the two groups were examined.Results The total effective rate of the observation group was higher than that of the control group(P<0.05),and its curative effect for refractory facial paralysis located above the geniculate ganglion was better than that of the control group(P<0.05).The color scale distribution of different disease locations in the two groups varied significantly(P<0.05),the higher the disease location,the higher the occurrence rate of cool zone and low temperature zone.After treatment,the reductions of the facial and periotic temperature difference between the healthy side and the affected side in the observation group were statistically different from those in the control group(P<0.05).Conclusion Muscle regions of meridians needling method has a better effect than facial three-line needling method for refractory facial paralysis.It can promote the microcirculation of the affected side of the face,improve the blood and oxygen supply to local tissues,and thus promote the repair of the peripheral facial nerve.展开更多
Summary: Fouty-five cases of temporomandibular joint dysfunction syndrome were diagnosed by Xray, excluding the organic diseases. The acupoints Xiaguan (ST 7), Jiache (ST 6), Yifeng (TE 17) and Hegu (LI 4) on...Summary: Fouty-five cases of temporomandibular joint dysfunction syndrome were diagnosed by Xray, excluding the organic diseases. The acupoints Xiaguan (ST 7), Jiache (ST 6), Yifeng (TE 17) and Hegu (LI 4) on the affected side were punctured first, after removal of needles, 5-7 layers of cotton cloth was placed on the above acupoints, then moxibustion with moxa-roll made of Chinese medicine was performed. Finally Dian-finger pressing, An-pressing and Rou stationary circular pressing with finger belly of the thumb were applied to the local region around the mandible joint for 3-5 min. After 1-2 courses of treatments, 45 cases all got effect.展开更多
文摘In the present paper, the authors make a simple comment on the influence of the theory of five elements of TCM on the acupuncturology from ① its influence on the meridian-collateral theory and acupoint system; ② its influence on acu-moxibustion therapeutics including the application of mother and son points for reinforcing and reducing, the application of the five element theory to the midnight-noon ebb-flow needling, and guiding point selection in different seasons; and ③ its influence on acupuncture techniques.
文摘Objective:To observe the effect of acupuncture on the expression of mitochondrial proteome in hippocampus of senescence-accelerated mouse prone g (SAMPg) mice models with Alzheimer disease (AD),and to explore the possible protective mechanism of acupuncture on mitochondria.Methods:Sixty 6-month-old male SAMP8 mice were randomly divided into an acupuncture at acupoint group,an acupuncture at non-acupoint group and a model group,20 mice in each group.The 20 male senescence-accelerated mouse/resistance 1 (SAMR1) mice of the same age were used as a normal control group.Shenshu (BL 23),Baihui (GV 20),Xuehai (SP 10) and Geshu (BL 17) were selected for acupuncture intervention in acupuncture at acupoint group.After an 8-week intervention,mitochondrial tissues were extracted from the hippocampus.Differentially expressed proteins were identified by subcellular organelle proteomics.Western blot was used to verify the expressions of some related proteins in hippocampal mitochondria.Results:Compared with the model group,there were 13 differentially expressed protein spots in the acupuncture at acupoint group,of which,9 were up-regulated,including neurofilament light polypeptide (NFL),actin (cytoplasmic 1,database ID:ACTB),tubulin beta-2A chain (TBB2A),tropomodulin-2 (TMOD2),pyruvate dehydrogenase E1 component subunit beta (PDHE1-β),NADH-ubiquinone oxidoreductase 75 kDa subunit (database ID:NDUS1),heat shock cognate 71 kDa protein (HSC71),pyruvate dehydrogenase E1 component subunit alpha (PDHE1-α) and ATP synthase beta subunit (ATP-β);4 were down-regulated,including glial fibrillary acidic protein (GFAP),pyruvate dehydrogenase phosphatase 1 (PDP1),mitochondrial-processing peptidase subunit alpha (MMP-α) and adenosine kinase (ADK).According to the information provided in the protein database,most of the differentially expressed proteins involve the regulation of mitochondrial function and structure.The expression levels of NFL and TBB2A in the normal control group and the acupuncture at acupoint group were significantly higher than those in the acupuncture at non-acupoint group (P〈0.05).ATP-β and NDUS1 expression levels were significantly higher in the acupuncture at acupoint group than those in the acupuncture at non-acupoint group (P〈0.05);there was no significant difference between the acupuncture at non-acupoint group and the model group (P〉0.05).Conclusion:Acupuncture may achieve the potential therapeutic effect on AD by regulating the structure and functional proteins of hippocampal mitochondria.
文摘Objective: To observe the clinical effect of thread-embedding therapy in treating insomnia due to heart-spleen deficiency. Methods: Sixty patients were randomized into an acupuncture group and a thread-embedding group, 30 in each. The acupuncture group was managed by acupuncture therapy, and the thread-embedding group was treated by thread-embedding therapy. Pittsburgh Sleep Quality Index (PSQI) was adopted for evaluation before and after treatments. Results: The total effective rate was 86.7% in the acupuncture group versus 96.7% in the thread-embedding group. After treatment, the PSQI scores were significantly different from those before treatment in both groups (P〈0.01); the scores in both two groups were mai'kedly different from each other after treatment (P〈0.01). Conclusion: Both acupuncture and thread-embedding therapies can effectively improve sleep quality of the patients, while thread-embedding therapy is comparatively less time-consuming, more convenient and with longer stimulation.
文摘Objective To explore the clinical efficacy of muscle regions of meridians needling method for refractory facial paralysis affecting different locations.Methods A total of 110 participants were randomized into an observation group and a control group,with 55 cases in each group.The observation group was treated with muscle regions of meridians needling method,and the control group was treated with conventional facial three-line needling method.The clinical efficacy was evaluated four weeks after the treatment.And the infrared imaging spectra of the two groups were examined.Results The total effective rate of the observation group was higher than that of the control group(P<0.05),and its curative effect for refractory facial paralysis located above the geniculate ganglion was better than that of the control group(P<0.05).The color scale distribution of different disease locations in the two groups varied significantly(P<0.05),the higher the disease location,the higher the occurrence rate of cool zone and low temperature zone.After treatment,the reductions of the facial and periotic temperature difference between the healthy side and the affected side in the observation group were statistically different from those in the control group(P<0.05).Conclusion Muscle regions of meridians needling method has a better effect than facial three-line needling method for refractory facial paralysis.It can promote the microcirculation of the affected side of the face,improve the blood and oxygen supply to local tissues,and thus promote the repair of the peripheral facial nerve.
文摘Summary: Fouty-five cases of temporomandibular joint dysfunction syndrome were diagnosed by Xray, excluding the organic diseases. The acupoints Xiaguan (ST 7), Jiache (ST 6), Yifeng (TE 17) and Hegu (LI 4) on the affected side were punctured first, after removal of needles, 5-7 layers of cotton cloth was placed on the above acupoints, then moxibustion with moxa-roll made of Chinese medicine was performed. Finally Dian-finger pressing, An-pressing and Rou stationary circular pressing with finger belly of the thumb were applied to the local region around the mandible joint for 3-5 min. After 1-2 courses of treatments, 45 cases all got effect.