A T-Q diagram based on entransy theory is applied to graphically and quantitatively describe the irreversibility of the heat transfer processes.The hot and cold composite curves can be obtained in the T-Q diagram.The ...A T-Q diagram based on entransy theory is applied to graphically and quantitatively describe the irreversibility of the heat transfer processes.The hot and cold composite curves can be obtained in the T-Q diagram.The entransy recovery and entransy dissipation that are affected by temperature differences can be obtained through the shaded area under the composite curves.The method for setting the energy target of the HENs in T-Q diagram based on entransy theory is proposed.A case study of the diesel oil hydrogenation unit is used to illustrate the application of the method.The results show that three different heat transfer temperature differences is 10 K,15 K and 20 K,and the entransy recovery is 5.498×10~7k W·K,5.377×10~7k W·K,5.257×10~7k W·K,respectively.And the entransy transfer efficiency is 92.29%,91.63%,90.99%.Thus,the energy-saving potential of the HENs is obtained by setting the energy target based on the entransy transfer efficiency.展开更多
Apoptosis plays a pivotal role in the etiology or pathogenesis of numerous medical disorders, and thus, target- ing of apoptotic cells may substantially advance patient care. In our quest for novel low-molecular-weigh...Apoptosis plays a pivotal role in the etiology or pathogenesis of numerous medical disorders, and thus, target- ing of apoptotic cells may substantially advance patient care. In our quest for novel low-molecular-weight probes for apoptosis, we focused on the uncommon amino acid T-carboxyglutamic acid （Gla）, which plays a vital role in the binding of clotting factors to negatively charged phospholipid surfaces. Based on the alkyl-malonic acid motif of Gla, we have developed and now present ML-10 （2-（5-fluoro-pentyl）-2-methyl-malonic acid, MW=206 Da）, the pro- totypical member of a novel family of small-molecule detectors of apoptosis. ML-10 was found to perform selective uptake and accumulation in apoptotic cells, while being excluded from either viable or necrotic cells. ML-10 uptake correlates with the apoptotic hallmarks of caspase activation, Annexin-V binding and disruption of mitochondrial membrane potential. The malonate moiety was found to be crucial for ML-10 function in apoptosis detection. ML- 10 responds to a unique complex of features of the cell in early apoptosis, comprising irreversible loss of membrane potential, permanent acidification of cell membrane and cytoplasm, and preservation of membrane integrity. ML-10 is therefore the most compact apoptosis probe known to date. Due to its fluorine atom, ML-10 is amenable to radio- labeling with the lSF isotope, towards its potential future use for clinical positron emission tomography imaging of apoptosis.展开更多
In this paper, the authors analyze the adequacy of GARCH-type models to analyze oil price behavior by applying two types of non-parametric tests, the Hinich portmanteau test for non-linear dependence and a frequency-d...In this paper, the authors analyze the adequacy of GARCH-type models to analyze oil price behavior by applying two types of non-parametric tests, the Hinich portmanteau test for non-linear dependence and a frequency-dominant test of time reversibility, the reverse test based on the bispectrum, to explore the high-order spectrum properties of the Mexican oil price series. The results suggest strong evidence of a non-linear structure and time irreversibility. Therefore, it does not comply with the i.i.d （independent and identically distributed） property. The non-linear dependence, however, is not consistent throughout the sample period, as indicated by a windowed test, suggesting episodic nonlinear dependence. The results imply that GARCH models cannot capture the series structure.展开更多
The Carnot-like heat engines are classified into three types （normal-, sub- and, super-dissipative） accord- ing to relations between the minimum irreversible entropy production in the ＂isothermal＂ processes and th...The Carnot-like heat engines are classified into three types （normal-, sub- and, super-dissipative） accord- ing to relations between the minimum irreversible entropy production in the ＂isothermal＂ processes and the time for completing those processes. The efficiencies at maximum power of normal-, sub- and super-dissipative Carnot-like heat engines are proved to be bounded between ηc/2 and ηc/ （2 - ηc ）, ηc /2 and ηc, 0 and ηc/ （2 - ηc ）, respectively. These bounds are also shared by linear, sub- and super-linear irreversible Carnot-like engines [Tu and Wang, Europhys. Left. 98 （2012） 40001] although the dissipative engines and the irreversible ones are inequivalent to each other.展开更多
KAM theorem of reversible system is used to provide a sufficient condition which guarantees the stability of a parabolic fixed point of reversible mappings. The main idea is to discuss when the parabolic thed point is...KAM theorem of reversible system is used to provide a sufficient condition which guarantees the stability of a parabolic fixed point of reversible mappings. The main idea is to discuss when the parabolic thed point is surrounded by closed invariant curves and thus exhibits stable behaviour.展开更多
基金Supported by the National Natural Science Foundation of China(21406124)
文摘A T-Q diagram based on entransy theory is applied to graphically and quantitatively describe the irreversibility of the heat transfer processes.The hot and cold composite curves can be obtained in the T-Q diagram.The entransy recovery and entransy dissipation that are affected by temperature differences can be obtained through the shaded area under the composite curves.The method for setting the energy target of the HENs in T-Q diagram based on entransy theory is proposed.A case study of the diesel oil hydrogenation unit is used to illustrate the application of the method.The results show that three different heat transfer temperature differences is 10 K,15 K and 20 K,and the entransy recovery is 5.498×10~7k W·K,5.377×10~7k W·K,5.257×10~7k W·K,respectively.And the entransy transfer efficiency is 92.29%,91.63%,90.99%.Thus,the energy-saving potential of the HENs is obtained by setting the energy target based on the entransy transfer efficiency.
文摘Apoptosis plays a pivotal role in the etiology or pathogenesis of numerous medical disorders, and thus, target- ing of apoptotic cells may substantially advance patient care. In our quest for novel low-molecular-weight probes for apoptosis, we focused on the uncommon amino acid T-carboxyglutamic acid （Gla）, which plays a vital role in the binding of clotting factors to negatively charged phospholipid surfaces. Based on the alkyl-malonic acid motif of Gla, we have developed and now present ML-10 （2-（5-fluoro-pentyl）-2-methyl-malonic acid, MW=206 Da）, the pro- totypical member of a novel family of small-molecule detectors of apoptosis. ML-10 was found to perform selective uptake and accumulation in apoptotic cells, while being excluded from either viable or necrotic cells. ML-10 uptake correlates with the apoptotic hallmarks of caspase activation, Annexin-V binding and disruption of mitochondrial membrane potential. The malonate moiety was found to be crucial for ML-10 function in apoptosis detection. ML- 10 responds to a unique complex of features of the cell in early apoptosis, comprising irreversible loss of membrane potential, permanent acidification of cell membrane and cytoplasm, and preservation of membrane integrity. ML-10 is therefore the most compact apoptosis probe known to date. Due to its fluorine atom, ML-10 is amenable to radio- labeling with the lSF isotope, towards its potential future use for clinical positron emission tomography imaging of apoptosis.
文摘In this paper, the authors analyze the adequacy of GARCH-type models to analyze oil price behavior by applying two types of non-parametric tests, the Hinich portmanteau test for non-linear dependence and a frequency-dominant test of time reversibility, the reverse test based on the bispectrum, to explore the high-order spectrum properties of the Mexican oil price series. The results suggest strong evidence of a non-linear structure and time irreversibility. Therefore, it does not comply with the i.i.d （independent and identically distributed） property. The non-linear dependence, however, is not consistent throughout the sample period, as indicated by a windowed test, suggesting episodic nonlinear dependence. The results imply that GARCH models cannot capture the series structure.
基金Supported by the National Natural Science Foundation of China under Grant No. 11075015the Fundamental Research Funds for the Central Universities
文摘The Carnot-like heat engines are classified into three types （normal-, sub- and, super-dissipative） accord- ing to relations between the minimum irreversible entropy production in the ＂isothermal＂ processes and the time for completing those processes. The efficiencies at maximum power of normal-, sub- and super-dissipative Carnot-like heat engines are proved to be bounded between ηc/2 and ηc/ （2 - ηc ）, ηc /2 and ηc, 0 and ηc/ （2 - ηc ）, respectively. These bounds are also shared by linear, sub- and super-linear irreversible Carnot-like engines [Tu and Wang, Europhys. Left. 98 （2012） 40001] although the dissipative engines and the irreversible ones are inequivalent to each other.
文摘KAM theorem of reversible system is used to provide a sufficient condition which guarantees the stability of a parabolic fixed point of reversible mappings. The main idea is to discuss when the parabolic thed point is surrounded by closed invariant curves and thus exhibits stable behaviour.
