Dear Editor,The Arabidopsis CONSTITUTIVELY PHOTOMORPHOGENIC1/ SUPPRESSOR OF PHYA-105 （COP1/SPA） complex is a key repressor of light signaling that inhibits light responses in dark- ness. It acts as an E3 ubiquitin l...Dear Editor,The Arabidopsis CONSTITUTIVELY PHOTOMORPHOGENIC1/ SUPPRESSOR OF PHYA-105 （COP1/SPA） complex is a key repressor of light signaling that inhibits light responses in dark- ness. It acts as an E3 ubiquitin ligase, which ubiquitinates posi- tively acting light-signaling intermediates, mainly transcription factors, thereby targeting them for proteolytic degradation by the 26S proteasome. In the light, photoreceptors directly interact with the COP1/SPA complex, leading to its inactivation, which subsequently allows the target transcription factors to accumu- late and initiate vast reprogramming of gene expression （Huang et al., 2014）.展开更多
文摘Dear Editor,The Arabidopsis CONSTITUTIVELY PHOTOMORPHOGENIC1/ SUPPRESSOR OF PHYA-105 （COP1/SPA） complex is a key repressor of light signaling that inhibits light responses in dark- ness. It acts as an E3 ubiquitin ligase, which ubiquitinates posi- tively acting light-signaling intermediates, mainly transcription factors, thereby targeting them for proteolytic degradation by the 26S proteasome. In the light, photoreceptors directly interact with the COP1/SPA complex, leading to its inactivation, which subsequently allows the target transcription factors to accumu- late and initiate vast reprogramming of gene expression （Huang et al., 2014）.
