Based on the Mg58.5Cu30.5Y11 alloy, 10% Ti, 10% Be and 10% Ti70Be30 （mole fraction） were respectively added to the alloy and samples with a diameter of 3 mm were fabricated by conventional Cu-mold casting method. Th...Based on the Mg58.5Cu30.5Y11 alloy, 10% Ti, 10% Be and 10% Ti70Be30 （mole fraction） were respectively added to the alloy and samples with a diameter of 3 mm were fabricated by conventional Cu-mold casting method. The phase constituent, thermal stability and microstructure of the alloys were investigated by using X-ray diffraction, differential scanning calorimetry and scanning electron microscopy, respectively. The effects of alloying elements Ti and Be on the microstructure and mechanical properties of Mg58.sCu3o.sYll alloy were discussed. The results show that CuTi phase is distributed in （Mg0.585Cu0.305Y0.11）90Ti10 and （Mg58.5Cu30.5Y11）90（Ti0.7Be0.3）10 alloys, while CuYBe glassy phase containing CuY crystals is embedded in the matrix of （Mg58.5Cu30.5Y11）90Be10 alloy. Under uniaxial compressive loading, the largest compressive fracture strengths for （Mg58.5Cu30.5Y11）90Ti10, （Mg58.5Cu30.5Y11）90Be10 and （Mg58.5Cu30.5Y11）90（Ti0.7Be0.3）10 alloys are 797.6, 952.6 and 1007.8 MPa, respectively, and the strengths are increased by about 17%, 40% and 48% compared with Mg58.5Cu30.5Y11 alloy. The strength reliability for the three alloys is much improved according to the strength distribution region of 10 samples of each alloy.展开更多
OBJECTIVE To compare the expression of the thyroid transcription factor-1 （TTF-1） in human normal adult type Ⅱ alveolar epithelial cells, embryonic pneumocytes and cancer cells of lung carcinoma and metastatic lymp...OBJECTIVE To compare the expression of the thyroid transcription factor-1 （TTF-1） in human normal adult type Ⅱ alveolar epithelial cells, embryonic pneumocytes and cancer cells of lung carcinoma and metastatic lymph nodes using a tissue microarray （TMA） along with paired conventional full sections, and to investigate the reliability of tissue microarrays in detecting protein expression in lung carcinoma. METHODS A lung carcinoma TMA including 765 cores was constructed. TTF-1 protein expression in both TMA and paired conventional full sections were detected by the immunohistochemical SP method using a monoclonal antibody to TTF-1. A PU （Positive Unit） of TTF-1 protein was assessed quantitatively by the Leica Q500MC image analysis system with results from the paired conventional full sections as controls. RESULTS There was no significance between TMA and paired conventional full sections in TTF-1 expression in different nuclei of the lung tissue. CONCLUSION TTF-1 protein expression in lung carcinoma detected by TMA was highly concordant with that of paired full sections. TMA is a reliable method in detecting protein expression.展开更多
Objective：To report the results of repair of skin defects in the extremities with arterialized venous flap harvested from the lateral aspect of the dorsum of the foot.Methods：Six cases of skin and soft tissue defect...Objective：To report the results of repair of skin defects in the extremities with arterialized venous flap harvested from the lateral aspect of the dorsum of the foot.Methods：Six cases of skin and soft tissue defects over the foot and hands were resurfaced by free arterialized venous flaps,including five patients with skin defects of the hands,and one with defects at the dorsum of the foot.The flaps were harvested from the lateral aspect of the dorsum of the foot with the sizes ranging from 2 cm×5.5 cm to 6 cm×11 cm.Two veins at the proximal margin of the flap were retained,one of which was anastomosed to a recipient bed artery to provide arterial inflow and the other was anastomosed to a recipient bed vein for venous outflow.Results：All flaps demonstrated mild edema and survived completely.Blisters appeared on four flaps.Using this technique,we achieved good functional and cosmetic results in this series.Conclusions：Dorsalis pedis arterialized venous flap with rich vascular communications could enhance peripheral perfusion and decrease congestion of venous flaps,thereby improves reliability and utility for extremity reconstruction.展开更多
基金Project(2011CB606301)supported by the National Basic Research Program of China
文摘Based on the Mg58.5Cu30.5Y11 alloy, 10% Ti, 10% Be and 10% Ti70Be30 （mole fraction） were respectively added to the alloy and samples with a diameter of 3 mm were fabricated by conventional Cu-mold casting method. The phase constituent, thermal stability and microstructure of the alloys were investigated by using X-ray diffraction, differential scanning calorimetry and scanning electron microscopy, respectively. The effects of alloying elements Ti and Be on the microstructure and mechanical properties of Mg58.sCu3o.sYll alloy were discussed. The results show that CuTi phase is distributed in （Mg0.585Cu0.305Y0.11）90Ti10 and （Mg58.5Cu30.5Y11）90（Ti0.7Be0.3）10 alloys, while CuYBe glassy phase containing CuY crystals is embedded in the matrix of （Mg58.5Cu30.5Y11）90Be10 alloy. Under uniaxial compressive loading, the largest compressive fracture strengths for （Mg58.5Cu30.5Y11）90Ti10, （Mg58.5Cu30.5Y11）90Be10 and （Mg58.5Cu30.5Y11）90（Ti0.7Be0.3）10 alloys are 797.6, 952.6 and 1007.8 MPa, respectively, and the strengths are increased by about 17%, 40% and 48% compared with Mg58.5Cu30.5Y11 alloy. The strength reliability for the three alloys is much improved according to the strength distribution region of 10 samples of each alloy.
基金the National Natural Sciences Foundation of China (No. 30271462)the science and technology planning project of Guangdong Province (No. 2KM04501S)the principal science and technology project of Guangzhou City (No. 2003Z2-E0061, E0062).
文摘OBJECTIVE To compare the expression of the thyroid transcription factor-1 （TTF-1） in human normal adult type Ⅱ alveolar epithelial cells, embryonic pneumocytes and cancer cells of lung carcinoma and metastatic lymph nodes using a tissue microarray （TMA） along with paired conventional full sections, and to investigate the reliability of tissue microarrays in detecting protein expression in lung carcinoma. METHODS A lung carcinoma TMA including 765 cores was constructed. TTF-1 protein expression in both TMA and paired conventional full sections were detected by the immunohistochemical SP method using a monoclonal antibody to TTF-1. A PU （Positive Unit） of TTF-1 protein was assessed quantitatively by the Leica Q500MC image analysis system with results from the paired conventional full sections as controls. RESULTS There was no significance between TMA and paired conventional full sections in TTF-1 expression in different nuclei of the lung tissue. CONCLUSION TTF-1 protein expression in lung carcinoma detected by TMA was highly concordant with that of paired full sections. TMA is a reliable method in detecting protein expression.
文摘Objective：To report the results of repair of skin defects in the extremities with arterialized venous flap harvested from the lateral aspect of the dorsum of the foot.Methods：Six cases of skin and soft tissue defects over the foot and hands were resurfaced by free arterialized venous flaps,including five patients with skin defects of the hands,and one with defects at the dorsum of the foot.The flaps were harvested from the lateral aspect of the dorsum of the foot with the sizes ranging from 2 cm×5.5 cm to 6 cm×11 cm.Two veins at the proximal margin of the flap were retained,one of which was anastomosed to a recipient bed artery to provide arterial inflow and the other was anastomosed to a recipient bed vein for venous outflow.Results：All flaps demonstrated mild edema and survived completely.Blisters appeared on four flaps.Using this technique,we achieved good functional and cosmetic results in this series.Conclusions：Dorsalis pedis arterialized venous flap with rich vascular communications could enhance peripheral perfusion and decrease congestion of venous flaps,thereby improves reliability and utility for extremity reconstruction.
