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自体颅骨粉末移植和膜引导再生技术修复兔颅骨缺损的组织学研究 被引量:3
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作者 陈敏建 陆婷 陈平 《组织工程与重建外科杂志》 2013年第6期311-314,共4页
目的应用自体颅骨粉末移植和膜引导再生技术修复兔颅骨缺损模型,观察其组织学演变过程。方法选取50只新西兰大白兔,建立直径1 cm的颅骨全层缺损模型。移植自体骨粉修复兔颅骨缺损,并在移植的骨粉上放置可吸收生物膜,以纤维蛋白胶固定。... 目的应用自体颅骨粉末移植和膜引导再生技术修复兔颅骨缺损模型,观察其组织学演变过程。方法选取50只新西兰大白兔,建立直径1 cm的颅骨全层缺损模型。移植自体骨粉修复兔颅骨缺损,并在移植的骨粉上放置可吸收生物膜,以纤维蛋白胶固定。术后2、4、6、8、12周取材进行组织学观察。结果术后2周,可观察到颅骨缺损区大量骨粉,炎性细胞、毛细血管和成纤维细胞由周围向内浸润,骨粉被吞噬吸收,周边小部分是新生骨,两者之间界限明显。术后4周,观察到骨粉吸收和新骨形成活跃区域向缺损中央内移较多,新生编织骨有所增粗,编织骨之间连接更为紧密,观察到的组织和细胞成分与术后2周时无明显变化。术后6周,基本观察不到未被吸收的骨粉,新生的编织骨变粗,联系更紧密。术后8周,完全观察不到骨粉,缺损中央部已形成单层新生骨,周边部形成的编织骨较为粗大,与正常骨紧密连接,形成初级骨髓腔。术后12周,缺损中央部形成双层新生骨,可见新生骨的改建和较为成熟的骨髓腔,腔内容物形态和成分与正常骨无区别。结论应用自体颅骨粉末移植和膜引导再生技术可以修复颅骨缺损,其组织学演变过程实质是引导性和诱导性骨再生的过程。 展开更多
关键词 生物膜 自体颅骨粉末 颅骨缺损 移植 修复 组织学演变
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Effect of cold rolling deformation on microstructure evolution and mechanical properties of spray formed Al−Zn−Mg−Cu−Cr alloys
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作者 Cai-he FAN Yi-hui LI +4 位作者 Qin WU Ling OU Ze-yi HU Yu-meng NI Jian-jun YANG 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS 2024年第8期2442-2454,共13页
The impact of cold rolling deformation,which was introduced after solid solution and before aging treatment,on microstructure evolution and mechanical properties of the as-extruded spray formed Al−9.8Zn−2.3Mg−1.73Cu−0... The impact of cold rolling deformation,which was introduced after solid solution and before aging treatment,on microstructure evolution and mechanical properties of the as-extruded spray formed Al−9.8Zn−2.3Mg−1.73Cu−0.13Cr(wt.%)alloy,was investigated.SEM,TEM,and EBSD were used to analyze the microstructures,and tensile tests were conducted to assess mechanical properties.The results indicate that the D1-T6 sample,subjected to 25%cold rolling deformation,exhibits finer grains(3.35μm)compared to the D0-T6 sample(grain size of 4.23μm)without cold rolling.Cold rolling refines the grains that grow in solution treatment.Due to the combined effects of finer and more dispersed precipitates,higher dislocation density and smaller grains,the yield strength and ultimate tensile strength of the D1-T6 sample can reach 663 and 737 MPa,respectively.In comparison to the as-extruded and D0-T6 samples,the yield strength of the D1-T6 sample increases by 415 and 92 MPa,respectively. 展开更多
关键词 Al−Zn−Mg−Cu alloy spray forming microstructure evolution mechanical properties strengthening mechanism
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Effect of quenching cooling rate on residual stress and microstructure evolution of 6061 aluminum alloy
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作者 HUANG Ke YI You-ping +4 位作者 HUANG Shi-quan HE Hai-lin LIU Jie HUA Hong-en TANG Yun-jian 《Journal of Central South University》 SCIE EI CAS 2024年第7期2167-2180,共14页
In this study,the cooling rate was manipulated by quenching with water of different temperatures(30,60 and 100℃).Surface and internal residual stresses in the quenched 6061 aluminum alloy samples were measured using ... In this study,the cooling rate was manipulated by quenching with water of different temperatures(30,60 and 100℃).Surface and internal residual stresses in the quenched 6061 aluminum alloy samples were measured using hole-drilling and crack compliance methods,respectively.Then,the processability of the quenched samples was evaluated at cryogenic temperatures.The mechanical properties of the as-aged samples were assessed,and microstructure evolution was analyzed.The surface residual stresses of samples W30℃,W60℃and W100℃is−178.7,−161.7 and−117.2 MPa,respectively along x-direction,respectively;and−191.2,−172.1 and−126.2 MPa,respectively along y-direction.The sample quenched in boiling water displaying the lowest residual stress(~34%and~60%reduction in the surface and core).The generation and distribution of quenching residual stress could be attributed to the lattice distortion gradient.Desirable plasticity was also exhibited in the samples with relatively low quenching cooling rates at cryogenic temperatures.The strengthes of the as-aged samples are 291.2 to 270.1 MPa as the quenching water temperature increase from 30℃to 100℃.Fine and homogeneous β"phases were observed in the as-aged sample quenched with boiling water due to the clusters and Guinier-Preston zones(GP zones)premature precipitated during quenching process. 展开更多
关键词 6061 aluminum alloy residual stress cooling rate cryogenic cooling mechanical properties microstructure evolution
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