[Objective] The experiment aimed to study laws of accumulation of starch in micro-endosperm maize kernel. [Method] The laws of accumulation of starch in maize embryo and OSK(the other section of a kernel except embryo...[Objective] The experiment aimed to study laws of accumulation of starch in micro-endosperm maize kernel. [Method] The laws of accumulation of starch in maize embryo and OSK(the other section of a kernel except embryo) of MEM(micro-endosperm maize) were studied in this experiment by taking Gaoyou 115 maize as control. [Result] The starch accumulation speed of MEM embryo was slightly lower than that of Gaoyou115 and the starch accumulation speed of MEM OSK was far lower than that of Gaoyou 115, so the starch content of the whole kernel of Gaoyou 115 was 3.4 to 4.5 times as high as that of MEM during harvesting. The embryo starch weight ration of Gaoyou 115 maize during harvesting was only 3% to 4% while that of MEM was 16% to 22%. Moreover, starch accumulation speeds of different MEM materials were different and there were significant differences in starch content during harvesting among different MEM materials. [Conclusion] The starch accumulation in MEM was slow, and MEM has widely variation on starch accumulation.展开更多
In Corley′s algorithm for all efficient spanning trees, final solutions include many spanning trees, which are not all efficient. In this paper, a new algorithm is presented, which corrects and modifies Corley′s alg...In Corley′s algorithm for all efficient spanning trees, final solutions include many spanning trees, which are not all efficient. In this paper, a new algorithm is presented, which corrects and modifies Corley′s algorithm. A necessary condition is developed for the subtree of an efficient spanning tree. According to the condition the new algorithm is established and its efficiency is proved.展开更多
In order to improve the effectiveness of the artificial intelligence (AI) planning based web service composition problem, a business domain oriented AI planning algorithm for web service composition is introduced. T...In order to improve the effectiveness of the artificial intelligence (AI) planning based web service composition problem, a business domain oriented AI planning algorithm for web service composition is introduced. The algorithm uses the proposed business relation model to minimize the searching space and uses the proposed goal distance as a heuristic rule. Compared with other algorithms tackling web service composition such as AI planning, the proposed algorithm focuses not only on how to convert the web service composition problem to the AI planning problem, but also exerts its effort on how to apply the business feature of web service composition into planning in order to improve the effectiveness. The experiment shows the better performance of the proposed algorithm.展开更多
With the increment of focal elements number in discernment framework,the computation amount in Dezert-Smarandache Theory (DSmT) will exponentially go up. This has been the bottleneck problem to block the wide applicat...With the increment of focal elements number in discernment framework,the computation amount in Dezert-Smarandache Theory (DSmT) will exponentially go up. This has been the bottleneck problem to block the wide application and development of DSmT. Aiming at this difficulty,in this paper,a kind of fast approximate reasoning method in hierarchical DSmT is proposed. Presently,this method is only fit for the case that there are only singletons with assignment in hyper-power set. These singletons in hyper-power set are forced to group through bintree or tri-tree technologies. At the same time,the assignments of singletons in those different groups corresponding to each source are added up respectively,in order to realize the mapping from the refined hyper-power set to the coarsened one. And then,two sources with the coarsened hyper-power set are combined together according to classical DSm Combination rule (DSmC) and Proportional Conflict Redistribution rule No. 5 (PCR5). The fused results in coarsened framework will be saved as the connecting weights between father and children nodes. And then,all assignments of singletons in different groups will be normalized respectively. Tree depth is set,in order to decide the iterative times in hierarchical system. Finally,by comparing new method with old one from different views,the superiority of new one over old one is testified well.展开更多
A kind of combining forecasting model based on the generalized weighted functional mean is proposed. Two kinds of parameter estimation methods with its weighting coefficients using the algorithm of quadratic programmi...A kind of combining forecasting model based on the generalized weighted functional mean is proposed. Two kinds of parameter estimation methods with its weighting coefficients using the algorithm of quadratic programming are given. The efficiencies of this combining forecasting model and the comparison of the two kinds of parameter estimation methods are demonstrated with an example. A conclusion is obtained, which is useful for the correct application of the above methods.展开更多
Amycolatopsis mediterranei is used for industry-scale production of rifamycin, which plays a vital role in antimyco- bacterial therapy. As the first sequenced genome of the genus Amycolatopsis, the chromosome of strai...Amycolatopsis mediterranei is used for industry-scale production of rifamycin, which plays a vital role in antimyco- bacterial therapy. As the first sequenced genome of the genus Amycolatopsis, the chromosome of strain U32 comprising 10 236 715 base pairs, is one of the largest prokaryotic genomes ever sequenced so far. Unlike the linear topology found in streptomycetes, this chromosome is circular, particularly similar to that of Saccharopolyspora erythraea and Nocardia farcinica, representing their close relationship in phylogeny and taxonomy. Although the predicted 9 228 protein-coding genes in the A. mediterranei genome shared the greatest number of orthologs with those of S. erythraea, it was unexpectedly followed by Streptomyces coelicolor rather than N. farcinica, indicating the distinct metabolic characteristics evolved via adaptation to diverse ecological niches. Besides a core region analogous to that common in streptomycetes, a novel 'quasicore' with typical core characteristics is defined within the non-core region, where 21 out of the total 26 gene clusters for secondary metabolite production are located. The rifamycin biosynthesis gene cluster located in the core encodes a cytochrome P450 enzyme essential for the conversion of rifamycin SV to B, revealed by comparing to the highly homologous cluster of the rifamycin B-producing strain S699 and further confirmed by genetic complementation. The genomic information of A. mediterranei demonstrates a metabolic network orchestrated not only for extensive utilization of various carbon sources and inorganic nitrogen compounds but also for effective funneling of metabolic intermediates into the secondary antibiotic synthesis process under the control of a seemingly complex regulatory mechanism.展开更多
In this paper, we consider the set partitioning problem with matroid constraint, which is a generation of the k-partitioning problem. The objective is to minimize the weight of the heaviest subset. We present an appro...In this paper, we consider the set partitioning problem with matroid constraint, which is a generation of the k-partitioning problem. The objective is to minimize the weight of the heaviest subset. We present an approximation algorithm, which consists of two sub-algorithms-the modified Edmonds' matroid partitioning algorithm and the exchange algorithm, for the problem. An estimation of the worst ratio for the algorithm is given.展开更多
The complexity of the physical demands of soccer requires the completion of a multi-component training programme. The development, planning, and implementation of such a programme are difficult due partly to the pract...The complexity of the physical demands of soccer requires the completion of a multi-component training programme. The development, planning, and implementation of such a programme are difficult due partly to the practical constraints related to the competitive schedule at the top level. The effective planning and organisation of training are therefore crucial to the effective delivery of the training stimulus for both individual players and the team. The aim of this article is to provide an overview of the principles of training that can be used to prepare players for the physical demands of soccer. Information relating to periodisation is supported by an outline of the strategies used to deliver the acute training stress in a soccer environment. The importance of monitoring to support the planning process is also reviewed.展开更多
AIM: To investigate the endoscopic features of pharyngeal superfi cial carcinoma and evaluate the utility of narrow-band imaging (NBI) for this disease. METHODS: In the present prospective study, 335 patients underwen...AIM: To investigate the endoscopic features of pharyngeal superfi cial carcinoma and evaluate the utility of narrow-band imaging (NBI) for this disease. METHODS: In the present prospective study, 335 patients underwent conventional white light (CWL) en-doscopy and non-magnifi ed/magnifi ed NBI endoscopy, followed by an endoscopic biopsy, for 445 superfi cial lesions in the oropharynx and hypopharynx. The macroscopic appearance of superfi cial lesions was categorized as either elevated (< 5 mm in height), flat, or depressed (not ulcerous). Superficial carcinoma (SC) was defi ned as a superfi cial lesion showing high-grade dysplasia or squamous cell carcinoma on histology. The color, delineation, and macroscopic appearances of the lesions were evaluated by CWL endoscopy. The ratio of the brownish area/intervascular brownish epithelium (IBE), as well as microvascular proliferation, dilation, and irregularities, was determined by non-magnifi ed/ magnifi ed NBI endoscopy. An experienced pathologist who was unaware of the endoscopic fi ndings made the histological diagnoses. By comparing endoscopic fi ndings with histology, we determined the endoscopic features of SC and evaluated the diagnostic utility of NBI. RESULTS: The 445 lesions were divided histologically into two groups: a non-SC group, including non-neoplasia and low-grade dysplasia cases, and an SC group. Of the 445 lesions examined, 333 were classified as non-SC and 112 were classif ied as SC. There were no significant differences in age, gender, or the location of the lesions between the patients in the two groups. The mean diameter of the SC lesions was signif icantly greater than that of non-SC lesions (11.0 ± 7.6 mm vs 4.6 ± 3.6 mm, respectively, P < 0.001). Comparisons of CWL endoscopy fi ndings for SC and non-SC lesions by univariate analysis revealed that the incidence of redness (72% vs 41%, respectively, P < 0.001) and a flat or depressed type of lesion (58% vs 44%, respectively, P = 0.013) was significantly higher in the SC group. Using non-magnifi ed NBI endoscopy, the incidence of a brownish area was signifi cantly higher for SC lesions (79% vs 57%, respectively, P < 0.001). On magnifi ed NBI endoscopy, the incidence of IBE (68% vs 33%, P < 0.001) and microvascular proliferation (82% vs 51%, P < 0.001), dilation (90% vs 76%, P =0.002), and irregularity (82% vs 31%, P < 0.001) was also signifi cantly higher for the SC compared with the non-SC lesions. Multivariate analysis revealed that the incidence of redness (P = 0.022) on CWL endoscopy and IBE (P < 0.001) and microvascular irregularities (P < 0.001) on magnif ied NBI endoscopy was signif icantly higher in SC than non-SC lesions. Redness alone exhibited signifi cantly higher sensitivity and signifi cantly lower specifi city for the diagnosis of SC compared with redness plus IBE and microvascular irregularities (72% vs 52%, P = 0.002; and 59% vs 92%, P < 0.001, respectively). The accuracy of redness plus IBE and irregularities for the diagnosis of SC was signifi cantly greater than using redness alone (82% vs 62%, respectively, P < 0.001). CONCLUSION: Redness, IBE, and microvascular irregularities appear to be closely related to SC lesions. Magnifi ed NBI endoscopy may increase the diagnostic accuracy of CWL endoscopy for SC.展开更多
Recently,inverse problems have attracted more and more attention in computational mathematics and become increasingly important in engineering applications.After the discretization,many of inverse problems are reduced...Recently,inverse problems have attracted more and more attention in computational mathematics and become increasingly important in engineering applications.After the discretization,many of inverse problems are reduced to linear systems.Due to the typical ill-posedness of inverse problems,the reduced linear systems are often illposed,especially when their scales are large.This brings great computational difficulty.Particularly,a small perturbation in the right side of an ill-posed linear system may cause a dramatical change in the solution.Therefore,regularization methods should be adopted for stable solutions.In this paper,a new class of accelerated iterative regularization methods is applied to solve this kind of large-scale ill-posed linear systems.An iterative scheme becomes a regularization method only when the iteration is early terminated.And a Morozov’s discrepancy principle is applied for the stop criterion.Compared with the conventional Landweber iteration,the new methods have acceleration effect,and can be compared to the well-known acceleratedν-method and Nesterov method.From the numerical results,it is observed that using appropriate discretization schemes,the proposed methods even have better behavior when comparing withν-method and Nesterov method.展开更多
To support the rapid automatic services composition and fulfill multi-quality of service (multi- QoS) demand, we propose a novel approach to realize services composition automatically by a prefihering process. Aimed...To support the rapid automatic services composition and fulfill multi-quality of service (multi- QoS) demand, we propose a novel approach to realize services composition automatically by a prefihering process. Aimed at a set of web services with similar functionality and different quality of service (QoS) , a semantic services chain is given and a corresponding constructing algorithm is proposed to construct the data structure. A pre-filtering process is put forward to find whether a composition service before planning exists. It can avoid aborted planning. An optimal planning algorithm is proposed which can choose the most suitable service from a lot of similar candidate services based on semantic service chains and multi-QoS values. The algorithms can improve the correctness and automation performances of automated semantic web services composition. As an example, a concrete composite process is analyzed. Experimental results show the validity of the composite process.展开更多
To figure out the distribution of temperature gradient along the girder height of steel-concrete composite box girder, combined with the mechanical characteristics of prestressed concrete composed box girder with corr...To figure out the distribution of temperature gradient along the girder height of steel-concrete composite box girder, combined with the mechanical characteristics of prestressed concrete composed box girder with corrugated steel webs, the calculation formulas of cross-sectional temperature stress along the span in a simply-supported beam bridge with composite section were derived under the conditions of static equilibrium and deformation compatibility of the beam element. The methods of calculating the maximum temperature stress value were discussed when the connectors are assumed rigid or flexible. Theoretical and numerical results indicate that the method proposed shows better precision for the calculation of temperature self-stress in both the top and the bottom surfaces of the box girder. Moreover, the regularity of temperature stress distribution at different locations along the girder span is that the largest axial force of the top or the bottom plate of the box girder is located in the midspan and spreads decreasingly until zero at both supported ends, and that the greatest longitudinal shear density in steel-concrete interface appears at both supported ends and then reduces gradually to zero in the midspan.展开更多
Objective To explore the transitive regularity of holistic constituents from the crude slices of the medicinal raw materials(MCS)to the formula granules(FG),fufang decoction(FD),and finally,the concentrated pills(CP)o...Objective To explore the transitive regularity of holistic constituents from the crude slices of the medicinal raw materials(MCS)to the formula granules(FG),fufang decoction(FD),and finally,the concentrated pills(CP)of Liuwei Dihuang Fufang(六味地黄复方,LWDHF).Methods Samples for MCS,FG,FD,and CP of LWDHF were obtained,and a fingerprint data-base was established using high-performance liquid chromatography(HPLC),by separating the samples in an XB-C18 column and analyzing the transitive regularity of components us-ing the total quantum statistical moment(TQSM),including total quantum zero moment(AUCT),total quantum first moment(MRTT),total quantum second moment(VRTT),and its similarity approach.The AUCT,MRTT,and VRTT were calculated based on the representative HPLC chromatograms of FG,FD,and CP of LWDHF.Results AUCT of FG,FD,and CP of LWDHF was 71804,46553,and 144646μV·s,respectively;MRTT was 14.43,14.54,and 18.85 min,respectively;and VRTT was 106.98,112.84,and 269.12 min2,respectively.Comparing the similarity of FG/FD,FG/CP and FD/CP of LWDHF,the TQSM similarity values were 98.66%,76.62%,and 75.37%,respectively,whereas the tradi-tional similarity evaluation values were 98.68%,85.43%,and 85.60%,respectively.Conclusion The results perform little distinction in the total composition between FG and FD,whereas some distinction existed between FD and CP.Experimental evidence,therefore indicates that FG could be used as the alternative of MCS in clinical applications.展开更多
This study aims at the relationship between the real estate market and Amman Stock Exchange, through the impact of three macroeconomic factors (GDP, inflation rate, and the population growth rate) and another three ...This study aims at the relationship between the real estate market and Amman Stock Exchange, through the impact of three macroeconomic factors (GDP, inflation rate, and the population growth rate) and another three factors from the microeconomic indicators (interest rate, remittances of Jordanian expatriates, and the loans provided by the Jordanian banks). The results show that the stock market is more sensitive to the microeconomic indicators than the real estate market, and responds more rapidly than the real estate market for the changes in the microeconomic indicators. The study presents some recommendations for the Jordanian companies who own or manage any investment portfolio to be aware for the existing relationship between the two markets, and to reflect this awareness in their strategic Plans, Particularly in the regression atmosphere that causes by global crisis.展开更多
This study aimed to identify the potential of shrub legumes as protein feed in West Timor. Eight shrub legumes, i.e., Clitoria ternatea Q5455 (CT Q5455), Clitoria ternatea millgara (CT millgara), Centrosema pascuo...This study aimed to identify the potential of shrub legumes as protein feed in West Timor. Eight shrub legumes, i.e., Clitoria ternatea Q5455 (CT Q5455), Clitoria ternatea millgara (CT millgara), Centrosema pascuorum bundey (CP bundey), Centrosema pascuorum molle (CP molle), Macroptilium bracteatum juanita (MB Juanita), Macroptilium bracteatum cadaarga (MB cadaarga), Dolichos lablab (DL) and Stylossanthes seabrana (SS) were evaluated for their yield and nutritive value in Randomized Block Design. Each legume was cultivated in four plots of different soil fertility as block (5 ~ 5 m2 per plot). Phosphorus (P) fertilizer was applied once just before planting at level of 50 kg ha~. Watering was done three times per week using sprinkler. The legumes were harvested at 120 days after planting (dap) in three sub-plots of 1 x 1 m2 size for their yield measurement. Samples of each legume was taken for Dry Matter (DM), Organic Matter (OM), Crude Protein (CP), cellulose, hemi-cellulose and lignin content and in vitro DM, OM and CP digestibility test. Data were statistically analyzed using Genstat release 12.2. The results showed that the legumes showed significantly different (P 〈 0.01) in biomass yield. The highest biomass yield was shown by SS (6,739 kg DM ha-l; 6,120 kg OM ha1 and 1,224 kg CP hal) and the lowest was by DL (1,294 kg DM ha^-1; 1,157 kg OM ha^-1 and 242 kg CP ha^-1). In general, there was no significant difference (P 〉 0.05) of DM digestibility of the eight legumes, except for DL which showed significantly highest (P 〈 0.01) DM and OM digestibility compared to the other.展开更多
A novel rule-based model for multi-stage multi-product scheduling problem(MMSP)in batch plants with parallel units is proposed.The scheduling problem is decomposed into two sub-problems of order assignment and order s...A novel rule-based model for multi-stage multi-product scheduling problem(MMSP)in batch plants with parallel units is proposed.The scheduling problem is decomposed into two sub-problems of order assignment and order sequencing.Firstly,hierarchical scheduling strategy is presented for solving the former sub-problem,where the multi-stage multi-product batch process is divided into multiple sequentially connected single process stages,and then the production of orders are arranged in each single stage by using forward order assignment strategy and backward order assignment strategy respectively according to the feature of scheduling objective.Line-up competition algorithm(LCA)is presented to find out optimal order sequence and order assignment rule,which can minimize total flow time or maximize total weighted process time.Computational results show that the proposed approach can obtain better solutions than those of the literature for all scheduling problems with more than 10 orders.Moreover,with the problem size increasing,the solutions obtained by the proposed approach are improved remarkably.The proposed approach has the potential to solve large size MMSP.展开更多
The diversity,community structure and seasonal variation in demersal nekton off the Changjiang(Yangtze)River estuary was evaluated using monthly trawl survey data,collected between December 2008 and November 2009.A to...The diversity,community structure and seasonal variation in demersal nekton off the Changjiang(Yangtze)River estuary was evaluated using monthly trawl survey data,collected between December 2008 and November 2009.A total of 95 species(56 teleosts,11 cephalopods,and 28 decapod crustaceans)from 69 genera,49 families and 15 orders were collected.These species could be classifi ed into six groups on the basis of temporal distribution patterns.The resident crab Ovalipes punctatus dominated the community,both in number and biomass.A clear seasonal succession was observed in the species composition.Cluster analysis revealed three primary seasonal groups corresponding to the samples collected in winter-spring,late spring-summer and late summer-autumn.The highest biomass and lowest diversity were observed in summer,while the lowest biomass and highest diversity in winter.The abundance-biomass comparison curves and community composition suggested that the investigated community was moderately disturbed.The results suggest that reduction in fi shing pressure and in the degree of seasonal hypoxia are essential for sustainable resource management off the Changjiang River estuary.展开更多
When the development level of a city is determined, its residents' level of participation and support to social organizations, especially the voluntarily participation to civil organizations, are taken into account, ...When the development level of a city is determined, its residents' level of participation and support to social organizations, especially the voluntarily participation to civil organizations, are taken into account, as well as, their level of utilization from city services. It is beneficial to organize civil groups who are sensitive to urban and environmental issues. In traditional Turkish settlements, it can be talked about the existence of such an organization as a natural process in social organizations including moral and humanistic values. The feeling of belonging had raised the environmental quality both physically and socially. Respect to the nature and human was the main principle of these settlements. Such organizations has displaced with the written rules and official or civil organizations in modern urban settlements. In these organizations, participation of the users to urban planning decisions is not directly, but indirectly. As people who live in modern settlements do not participate to the planning and building process, they have not felt themselves belong to the place. The environmental quality and respect to the nature and human have been lessened in these modern settlements. This study focuses on the participation of users on planning and building housing environments in traditional and modern Turkish settlements and the comparison of them with their positive and negative results with the examples given.展开更多
The social endeavors for Agrarian Reform in Brazil have a history of at least sixty years. Throughout this time, distinct political regimes, increased land concentration, disordered urbanization and the development of...The social endeavors for Agrarian Reform in Brazil have a history of at least sixty years. Throughout this time, distinct political regimes, increased land concentration, disordered urbanization and the development of a dynamic agribusiness sector inserted in global economy led to both the aggravation of social conflicts over land in Northern and Southern Brazil as well as new inquiries on the features necessary for an efficient Agrarian Reform Plan in the authors' country. Focused on the agrarian reform projects in the Brazilian Amazon, this work discusses on the political and methodological perspectives drawn in II PNRA (second National Plan of Agrarian Reform). The authors frame their account mostly along the theoretical scaffolding provided by the Bloomington School of Institutional Analysis. The authors analyze the multiple challenges facing the organization and the maintenance of the institutional structure designed to facilitate participatory planning and governance of collective resources in periurban settlements. The authors portrait these settlements as highly complex socio-ecological systems wherein socioeconomic asymmetries, cultural diversity and poor social capital and education promote political and ideological disputes that jeopardize safeguarding global commons.展开更多
基金Supported by the National Natural Science Foundation of China(30671307)the Innovation Project of Postgraduate Educationof Guangxi (2006105930901D08)~~
文摘[Objective] The experiment aimed to study laws of accumulation of starch in micro-endosperm maize kernel. [Method] The laws of accumulation of starch in maize embryo and OSK(the other section of a kernel except embryo) of MEM(micro-endosperm maize) were studied in this experiment by taking Gaoyou 115 maize as control. [Result] The starch accumulation speed of MEM embryo was slightly lower than that of Gaoyou115 and the starch accumulation speed of MEM OSK was far lower than that of Gaoyou 115, so the starch content of the whole kernel of Gaoyou 115 was 3.4 to 4.5 times as high as that of MEM during harvesting. The embryo starch weight ration of Gaoyou 115 maize during harvesting was only 3% to 4% while that of MEM was 16% to 22%. Moreover, starch accumulation speeds of different MEM materials were different and there were significant differences in starch content during harvesting among different MEM materials. [Conclusion] The starch accumulation in MEM was slow, and MEM has widely variation on starch accumulation.
文摘In Corley′s algorithm for all efficient spanning trees, final solutions include many spanning trees, which are not all efficient. In this paper, a new algorithm is presented, which corrects and modifies Corley′s algorithm. A necessary condition is developed for the subtree of an efficient spanning tree. According to the condition the new algorithm is established and its efficiency is proved.
基金The National Key Technologies R & D Program of China during the 10th Five-Year Plan Period(No2004BA721A05)
文摘In order to improve the effectiveness of the artificial intelligence (AI) planning based web service composition problem, a business domain oriented AI planning algorithm for web service composition is introduced. The algorithm uses the proposed business relation model to minimize the searching space and uses the proposed goal distance as a heuristic rule. Compared with other algorithms tackling web service composition such as AI planning, the proposed algorithm focuses not only on how to convert the web service composition problem to the AI planning problem, but also exerts its effort on how to apply the business feature of web service composition into planning in order to improve the effectiveness. The experiment shows the better performance of the proposed algorithm.
基金Supported by the National Natural Science Foundation of China (No. 60804063)
文摘With the increment of focal elements number in discernment framework,the computation amount in Dezert-Smarandache Theory (DSmT) will exponentially go up. This has been the bottleneck problem to block the wide application and development of DSmT. Aiming at this difficulty,in this paper,a kind of fast approximate reasoning method in hierarchical DSmT is proposed. Presently,this method is only fit for the case that there are only singletons with assignment in hyper-power set. These singletons in hyper-power set are forced to group through bintree or tri-tree technologies. At the same time,the assignments of singletons in those different groups corresponding to each source are added up respectively,in order to realize the mapping from the refined hyper-power set to the coarsened one. And then,two sources with the coarsened hyper-power set are combined together according to classical DSm Combination rule (DSmC) and Proportional Conflict Redistribution rule No. 5 (PCR5). The fused results in coarsened framework will be saved as the connecting weights between father and children nodes. And then,all assignments of singletons in different groups will be normalized respectively. Tree depth is set,in order to decide the iterative times in hierarchical system. Finally,by comparing new method with old one from different views,the superiority of new one over old one is testified well.
文摘A kind of combining forecasting model based on the generalized weighted functional mean is proposed. Two kinds of parameter estimation methods with its weighting coefficients using the algorithm of quadratic programming are given. The efficiencies of this combining forecasting model and the comparison of the two kinds of parameter estimation methods are demonstrated with an example. A conclusion is obtained, which is useful for the correct application of the above methods.
基金This paper is dedicated to the late Professor JS Chiao, who initiated the research in China for rifamycin production employing A. mediterranei more than 30 years ago and who continued the endeavor to resolve the mechanism of the 'nitrate stimulating effect' up to the last breath of his life. This work was supported by the National Natural Science Foundation of China (30830002), the National High Technology Research and Development Program of China (2007AA021301, 2007AA021503), and the Research Unit Fund of Li Ka Shing Institute of Health Sciences (7103506).
文摘Amycolatopsis mediterranei is used for industry-scale production of rifamycin, which plays a vital role in antimyco- bacterial therapy. As the first sequenced genome of the genus Amycolatopsis, the chromosome of strain U32 comprising 10 236 715 base pairs, is one of the largest prokaryotic genomes ever sequenced so far. Unlike the linear topology found in streptomycetes, this chromosome is circular, particularly similar to that of Saccharopolyspora erythraea and Nocardia farcinica, representing their close relationship in phylogeny and taxonomy. Although the predicted 9 228 protein-coding genes in the A. mediterranei genome shared the greatest number of orthologs with those of S. erythraea, it was unexpectedly followed by Streptomyces coelicolor rather than N. farcinica, indicating the distinct metabolic characteristics evolved via adaptation to diverse ecological niches. Besides a core region analogous to that common in streptomycetes, a novel 'quasicore' with typical core characteristics is defined within the non-core region, where 21 out of the total 26 gene clusters for secondary metabolite production are located. The rifamycin biosynthesis gene cluster located in the core encodes a cytochrome P450 enzyme essential for the conversion of rifamycin SV to B, revealed by comparing to the highly homologous cluster of the rifamycin B-producing strain S699 and further confirmed by genetic complementation. The genomic information of A. mediterranei demonstrates a metabolic network orchestrated not only for extensive utilization of various carbon sources and inorganic nitrogen compounds but also for effective funneling of metabolic intermediates into the secondary antibiotic synthesis process under the control of a seemingly complex regulatory mechanism.
基金Project (No. 10671177) supported by the National Natural Science Foundation of China
文摘In this paper, we consider the set partitioning problem with matroid constraint, which is a generation of the k-partitioning problem. The objective is to minimize the weight of the heaviest subset. We present an approximation algorithm, which consists of two sub-algorithms-the modified Edmonds' matroid partitioning algorithm and the exchange algorithm, for the problem. An estimation of the worst ratio for the algorithm is given.
文摘The complexity of the physical demands of soccer requires the completion of a multi-component training programme. The development, planning, and implementation of such a programme are difficult due partly to the practical constraints related to the competitive schedule at the top level. The effective planning and organisation of training are therefore crucial to the effective delivery of the training stimulus for both individual players and the team. The aim of this article is to provide an overview of the principles of training that can be used to prepare players for the physical demands of soccer. Information relating to periodisation is supported by an outline of the strategies used to deliver the acute training stress in a soccer environment. The importance of monitoring to support the planning process is also reviewed.
基金Supported by A Grant-in-Aid for Cancer Research (18-8) from the Ministry of Health, Labour and Welfare of Japan
文摘AIM: To investigate the endoscopic features of pharyngeal superfi cial carcinoma and evaluate the utility of narrow-band imaging (NBI) for this disease. METHODS: In the present prospective study, 335 patients underwent conventional white light (CWL) en-doscopy and non-magnifi ed/magnifi ed NBI endoscopy, followed by an endoscopic biopsy, for 445 superfi cial lesions in the oropharynx and hypopharynx. The macroscopic appearance of superfi cial lesions was categorized as either elevated (< 5 mm in height), flat, or depressed (not ulcerous). Superficial carcinoma (SC) was defi ned as a superfi cial lesion showing high-grade dysplasia or squamous cell carcinoma on histology. The color, delineation, and macroscopic appearances of the lesions were evaluated by CWL endoscopy. The ratio of the brownish area/intervascular brownish epithelium (IBE), as well as microvascular proliferation, dilation, and irregularities, was determined by non-magnifi ed/ magnifi ed NBI endoscopy. An experienced pathologist who was unaware of the endoscopic fi ndings made the histological diagnoses. By comparing endoscopic fi ndings with histology, we determined the endoscopic features of SC and evaluated the diagnostic utility of NBI. RESULTS: The 445 lesions were divided histologically into two groups: a non-SC group, including non-neoplasia and low-grade dysplasia cases, and an SC group. Of the 445 lesions examined, 333 were classified as non-SC and 112 were classif ied as SC. There were no significant differences in age, gender, or the location of the lesions between the patients in the two groups. The mean diameter of the SC lesions was signif icantly greater than that of non-SC lesions (11.0 ± 7.6 mm vs 4.6 ± 3.6 mm, respectively, P < 0.001). Comparisons of CWL endoscopy fi ndings for SC and non-SC lesions by univariate analysis revealed that the incidence of redness (72% vs 41%, respectively, P < 0.001) and a flat or depressed type of lesion (58% vs 44%, respectively, P = 0.013) was significantly higher in the SC group. Using non-magnifi ed NBI endoscopy, the incidence of a brownish area was signifi cantly higher for SC lesions (79% vs 57%, respectively, P < 0.001). On magnifi ed NBI endoscopy, the incidence of IBE (68% vs 33%, P < 0.001) and microvascular proliferation (82% vs 51%, P < 0.001), dilation (90% vs 76%, P =0.002), and irregularity (82% vs 31%, P < 0.001) was also signifi cantly higher for the SC compared with the non-SC lesions. Multivariate analysis revealed that the incidence of redness (P = 0.022) on CWL endoscopy and IBE (P < 0.001) and microvascular irregularities (P < 0.001) on magnif ied NBI endoscopy was signif icantly higher in SC than non-SC lesions. Redness alone exhibited signifi cantly higher sensitivity and signifi cantly lower specifi city for the diagnosis of SC compared with redness plus IBE and microvascular irregularities (72% vs 52%, P = 0.002; and 59% vs 92%, P < 0.001, respectively). The accuracy of redness plus IBE and irregularities for the diagnosis of SC was signifi cantly greater than using redness alone (82% vs 62%, respectively, P < 0.001). CONCLUSION: Redness, IBE, and microvascular irregularities appear to be closely related to SC lesions. Magnifi ed NBI endoscopy may increase the diagnostic accuracy of CWL endoscopy for SC.
基金supported by the Natural Science Foundation of China (Nos. 11971230, 12071215)the Fundamental Research Funds for the Central Universities(No. NS2018047)the 2019 Graduate Innovation Base(Laboratory)Open Fund of Jiangsu Province(No. Kfjj20190804)
文摘Recently,inverse problems have attracted more and more attention in computational mathematics and become increasingly important in engineering applications.After the discretization,many of inverse problems are reduced to linear systems.Due to the typical ill-posedness of inverse problems,the reduced linear systems are often illposed,especially when their scales are large.This brings great computational difficulty.Particularly,a small perturbation in the right side of an ill-posed linear system may cause a dramatical change in the solution.Therefore,regularization methods should be adopted for stable solutions.In this paper,a new class of accelerated iterative regularization methods is applied to solve this kind of large-scale ill-posed linear systems.An iterative scheme becomes a regularization method only when the iteration is early terminated.And a Morozov’s discrepancy principle is applied for the stop criterion.Compared with the conventional Landweber iteration,the new methods have acceleration effect,and can be compared to the well-known acceleratedν-method and Nesterov method.From the numerical results,it is observed that using appropriate discretization schemes,the proposed methods even have better behavior when comparing withν-method and Nesterov method.
基金Supported by the National Natural Science Foundation of China (No. 61201252, 60775037) , Humanities and Social Sciences Foundation of the Ministry of Education (No. 10YJC870046 ), Natural Science Research Key Project of Anhui Provincial Higher Education (No. KJ2011 A128) , Soft Science Project of Anhui Province ( No. 11020503009).
文摘To support the rapid automatic services composition and fulfill multi-quality of service (multi- QoS) demand, we propose a novel approach to realize services composition automatically by a prefihering process. Aimed at a set of web services with similar functionality and different quality of service (QoS) , a semantic services chain is given and a corresponding constructing algorithm is proposed to construct the data structure. A pre-filtering process is put forward to find whether a composition service before planning exists. It can avoid aborted planning. An optimal planning algorithm is proposed which can choose the most suitable service from a lot of similar candidate services based on semantic service chains and multi-QoS values. The algorithms can improve the correctness and automation performances of automated semantic web services composition. As an example, a concrete composite process is analyzed. Experimental results show the validity of the composite process.
基金Supported by National Natural Science Foundation of China (No. 50978105)
文摘To figure out the distribution of temperature gradient along the girder height of steel-concrete composite box girder, combined with the mechanical characteristics of prestressed concrete composed box girder with corrugated steel webs, the calculation formulas of cross-sectional temperature stress along the span in a simply-supported beam bridge with composite section were derived under the conditions of static equilibrium and deformation compatibility of the beam element. The methods of calculating the maximum temperature stress value were discussed when the connectors are assumed rigid or flexible. Theoretical and numerical results indicate that the method proposed shows better precision for the calculation of temperature self-stress in both the top and the bottom surfaces of the box girder. Moreover, the regularity of temperature stress distribution at different locations along the girder span is that the largest axial force of the top or the bottom plate of the box girder is located in the midspan and spreads decreasingly until zero at both supported ends, and that the greatest longitudinal shear density in steel-concrete interface appears at both supported ends and then reduces gradually to zero in the midspan.
基金Hunan Provincial Natural Science Foundation of China(2019JJ40220 and 2021JJ30514)Hunan Provincial Administration of Traditional Chinese Medicine(2021204and 2021073)+1 种基金Scientific Research Fund of Hunan Provincial Education Department(2021204 and 2021073)Pharmaceutical Open Fund of Domestic First-class Disciplines(Cultivation)of Hunan Province(2018YX11)。
文摘Objective To explore the transitive regularity of holistic constituents from the crude slices of the medicinal raw materials(MCS)to the formula granules(FG),fufang decoction(FD),and finally,the concentrated pills(CP)of Liuwei Dihuang Fufang(六味地黄复方,LWDHF).Methods Samples for MCS,FG,FD,and CP of LWDHF were obtained,and a fingerprint data-base was established using high-performance liquid chromatography(HPLC),by separating the samples in an XB-C18 column and analyzing the transitive regularity of components us-ing the total quantum statistical moment(TQSM),including total quantum zero moment(AUCT),total quantum first moment(MRTT),total quantum second moment(VRTT),and its similarity approach.The AUCT,MRTT,and VRTT were calculated based on the representative HPLC chromatograms of FG,FD,and CP of LWDHF.Results AUCT of FG,FD,and CP of LWDHF was 71804,46553,and 144646μV·s,respectively;MRTT was 14.43,14.54,and 18.85 min,respectively;and VRTT was 106.98,112.84,and 269.12 min2,respectively.Comparing the similarity of FG/FD,FG/CP and FD/CP of LWDHF,the TQSM similarity values were 98.66%,76.62%,and 75.37%,respectively,whereas the tradi-tional similarity evaluation values were 98.68%,85.43%,and 85.60%,respectively.Conclusion The results perform little distinction in the total composition between FG and FD,whereas some distinction existed between FD and CP.Experimental evidence,therefore indicates that FG could be used as the alternative of MCS in clinical applications.
文摘This study aims at the relationship between the real estate market and Amman Stock Exchange, through the impact of three macroeconomic factors (GDP, inflation rate, and the population growth rate) and another three factors from the microeconomic indicators (interest rate, remittances of Jordanian expatriates, and the loans provided by the Jordanian banks). The results show that the stock market is more sensitive to the microeconomic indicators than the real estate market, and responds more rapidly than the real estate market for the changes in the microeconomic indicators. The study presents some recommendations for the Jordanian companies who own or manage any investment portfolio to be aware for the existing relationship between the two markets, and to reflect this awareness in their strategic Plans, Particularly in the regression atmosphere that causes by global crisis.
文摘This study aimed to identify the potential of shrub legumes as protein feed in West Timor. Eight shrub legumes, i.e., Clitoria ternatea Q5455 (CT Q5455), Clitoria ternatea millgara (CT millgara), Centrosema pascuorum bundey (CP bundey), Centrosema pascuorum molle (CP molle), Macroptilium bracteatum juanita (MB Juanita), Macroptilium bracteatum cadaarga (MB cadaarga), Dolichos lablab (DL) and Stylossanthes seabrana (SS) were evaluated for their yield and nutritive value in Randomized Block Design. Each legume was cultivated in four plots of different soil fertility as block (5 ~ 5 m2 per plot). Phosphorus (P) fertilizer was applied once just before planting at level of 50 kg ha~. Watering was done three times per week using sprinkler. The legumes were harvested at 120 days after planting (dap) in three sub-plots of 1 x 1 m2 size for their yield measurement. Samples of each legume was taken for Dry Matter (DM), Organic Matter (OM), Crude Protein (CP), cellulose, hemi-cellulose and lignin content and in vitro DM, OM and CP digestibility test. Data were statistically analyzed using Genstat release 12.2. The results showed that the legumes showed significantly different (P 〈 0.01) in biomass yield. The highest biomass yield was shown by SS (6,739 kg DM ha-l; 6,120 kg OM ha1 and 1,224 kg CP hal) and the lowest was by DL (1,294 kg DM ha^-1; 1,157 kg OM ha^-1 and 242 kg CP ha^-1). In general, there was no significant difference (P 〉 0.05) of DM digestibility of the eight legumes, except for DL which showed significantly highest (P 〈 0.01) DM and OM digestibility compared to the other.
基金Supported by the National Natural Science Foundation of China(21376185)
文摘A novel rule-based model for multi-stage multi-product scheduling problem(MMSP)in batch plants with parallel units is proposed.The scheduling problem is decomposed into two sub-problems of order assignment and order sequencing.Firstly,hierarchical scheduling strategy is presented for solving the former sub-problem,where the multi-stage multi-product batch process is divided into multiple sequentially connected single process stages,and then the production of orders are arranged in each single stage by using forward order assignment strategy and backward order assignment strategy respectively according to the feature of scheduling objective.Line-up competition algorithm(LCA)is presented to find out optimal order sequence and order assignment rule,which can minimize total flow time or maximize total weighted process time.Computational results show that the proposed approach can obtain better solutions than those of the literature for all scheduling problems with more than 10 orders.Moreover,with the problem size increasing,the solutions obtained by the proposed approach are improved remarkably.The proposed approach has the potential to solve large size MMSP.
基金Supported by the National Key Technology R&D Program of China(No.2007BAD43B01)the National Special Research Fund for Non-Profit Sector(Agriculture)(No.201303047)the Special Fund of Chinese Central Government for Basic Scientific Research Operations in Commonweal Research Institutes(No.2008T04)
文摘The diversity,community structure and seasonal variation in demersal nekton off the Changjiang(Yangtze)River estuary was evaluated using monthly trawl survey data,collected between December 2008 and November 2009.A total of 95 species(56 teleosts,11 cephalopods,and 28 decapod crustaceans)from 69 genera,49 families and 15 orders were collected.These species could be classifi ed into six groups on the basis of temporal distribution patterns.The resident crab Ovalipes punctatus dominated the community,both in number and biomass.A clear seasonal succession was observed in the species composition.Cluster analysis revealed three primary seasonal groups corresponding to the samples collected in winter-spring,late spring-summer and late summer-autumn.The highest biomass and lowest diversity were observed in summer,while the lowest biomass and highest diversity in winter.The abundance-biomass comparison curves and community composition suggested that the investigated community was moderately disturbed.The results suggest that reduction in fi shing pressure and in the degree of seasonal hypoxia are essential for sustainable resource management off the Changjiang River estuary.
文摘When the development level of a city is determined, its residents' level of participation and support to social organizations, especially the voluntarily participation to civil organizations, are taken into account, as well as, their level of utilization from city services. It is beneficial to organize civil groups who are sensitive to urban and environmental issues. In traditional Turkish settlements, it can be talked about the existence of such an organization as a natural process in social organizations including moral and humanistic values. The feeling of belonging had raised the environmental quality both physically and socially. Respect to the nature and human was the main principle of these settlements. Such organizations has displaced with the written rules and official or civil organizations in modern urban settlements. In these organizations, participation of the users to urban planning decisions is not directly, but indirectly. As people who live in modern settlements do not participate to the planning and building process, they have not felt themselves belong to the place. The environmental quality and respect to the nature and human have been lessened in these modern settlements. This study focuses on the participation of users on planning and building housing environments in traditional and modern Turkish settlements and the comparison of them with their positive and negative results with the examples given.
文摘The social endeavors for Agrarian Reform in Brazil have a history of at least sixty years. Throughout this time, distinct political regimes, increased land concentration, disordered urbanization and the development of a dynamic agribusiness sector inserted in global economy led to both the aggravation of social conflicts over land in Northern and Southern Brazil as well as new inquiries on the features necessary for an efficient Agrarian Reform Plan in the authors' country. Focused on the agrarian reform projects in the Brazilian Amazon, this work discusses on the political and methodological perspectives drawn in II PNRA (second National Plan of Agrarian Reform). The authors frame their account mostly along the theoretical scaffolding provided by the Bloomington School of Institutional Analysis. The authors analyze the multiple challenges facing the organization and the maintenance of the institutional structure designed to facilitate participatory planning and governance of collective resources in periurban settlements. The authors portrait these settlements as highly complex socio-ecological systems wherein socioeconomic asymmetries, cultural diversity and poor social capital and education promote political and ideological disputes that jeopardize safeguarding global commons.