Direction relation is an important spatial relation. Descriptions and representations for direction relations have different levels of detail because of the varying dimensions of spatial objects and different scales o...Direction relation is an important spatial relation. Descriptions and representations for direction relations have different levels of detail because of the varying dimensions of spatial objects and different scales of the embedding spaces. Based on a direction- relation matrix, the hierarchical frame of spatial direction relations which partitions direction relations orderly and thoroughly is built. Interior direction relations are used to perfect the representation of direction relations and the binary-encoding idea is creatively applied to construct an interior detailed matrix describing multiple interior direction relations by a uniform matrix. The model integrates topological information into the description model for direction relations, which will lay the foundations of spatial compositive reasoning.展开更多
Method development has always been and will continue to be a core driving force of microbiome science, In this perspective, we argue that in the next decade, method development in microbiome analysis will be driven by...Method development has always been and will continue to be a core driving force of microbiome science, In this perspective, we argue that in the next decade, method development in microbiome analysis will be driven by three key changes in both ways of thinking and technological platforms： ① a shift from dissecting microbiota structure by sequencing to tracking microbiota state, function, and intercellular interaction via imaging; ② a shift from interrogating a consortium or population of cells to probing individual cells; and ③a shift from microbiome data analysis to microbiome data science. Some of the recent methoddevelopment efforts by Chinese microbiome scientists and their international collaborators that underlie these technological trends are highlighted here. It is our belief that the China Microbiome Initiative has the opportunity to deliver outstanding ＂Made-in-China＂ tools to the international research community, by building an ambitious, competitive, and collaborative program at the forefront of method development for microbiome science.展开更多
For digitalization of traditional Chinese medicine(TCM),research is being conducted on objectivization of diagnosis and treatment,mathematical models of TCM theories,and application of modern information technology to...For digitalization of traditional Chinese medicine(TCM),research is being conducted on objectivization of diagnosis and treatment,mathematical models of TCM theories,and application of modern information technology to digitize the vast amounts of existing information.However,the author believes that TCM practitioners should first conduct a systematic and comprehensive refined analysis on the knowledge of TCM and unify data elements used in computer intelligence to avoid ambiguity.Thus,we must overcome the epistemological constraints and carefully analyze the relationship among data elements to achieve systematic results and administer TCM appropriately.展开更多
The paper study improved K-means algorithm and establish indicators to classify customers according to RFM model. Experimental results show that, the new algorithm has good convergence and stability, it has better tha...The paper study improved K-means algorithm and establish indicators to classify customers according to RFM model. Experimental results show that, the new algorithm has good convergence and stability, it has better than single use of FKP algorithms for clustering. Finally the paper study the application of clustering in customer segmentation of mobile communication enterprise. It discusses the basic theory, customer segmentation methods and steps, the customer segmentation model based on consumption behavior psychology, and the segmentation model is successfully applied to the process of marketing decision support.展开更多
The mitochondrial cytochrome b gene was isolated from the caudal fin of Oryzias latipes and PCR was undertaken to determine phylogeny. The nucleotide sequence of the complete cytochrome b gene including the 5＇ and 3...The mitochondrial cytochrome b gene was isolated from the caudal fin of Oryzias latipes and PCR was undertaken to determine phylogeny. The nucleotide sequence of the complete cytochrome b gene including the 5＇ and 3＇ ends was 1,143 base pairs （bp） and 1,137 bp encoding 380 and 378 amino acids in the K-11 strain and HS strain, respectively. In addition, higher substitutions both in base and amino acid residues occurred more frequently between the former control （Hd-rR strain） and HS strains than the K-I 1 strain. Approximately similar values in polymorphism, as assessed by restriction endonuclease digestion, were detected when utilizing 20 different enzymes. Therefore, the evolutionary processes were unlikely to involve common ancestors, especially between the K-11 strain and HS strains, in O. latipes populations in Japan. The sequence had been deposited in GenBank Data Base under accession number AB480878 （K-I I strain） and AB480879 （HS strain）.展开更多
Causation is a distinct concept from association and more important than association inepidemiologic studies.This paper proposes the concept of uniform non-confounding for causal distributioneffects over multiple cova...Causation is a distinct concept from association and more important than association inepidemiologic studies.This paper proposes the concept of uniform non-confounding for causal distributioneffects over multiple covariates,and gives the sufficient conditions for uniform non-confoundingover a covariate set C including confounders or non-confounders,and also shows the conditions forconditionally non-confounding in the subpopulations.All these conditions can be tested by observeddata.展开更多
Cyprinidae is the biggest family of freshwater fish, but the phylogenetic relationships among its higher-level taxa are not yet fully resolved. In this study, we used the nuclear recombination activating gene 2 and th...Cyprinidae is the biggest family of freshwater fish, but the phylogenetic relationships among its higher-level taxa are not yet fully resolved. In this study, we used the nuclear recombination activating gene 2 and the mitochondrial 16S ribosomal RNA and cytochrome b genes to reconstruct cyprinid phylogeny. Our aims were to （i） demonstrate the effects of partitioned phylo- genetic analyses on phylogeny reconstruction of cyprinid fishes; （ii） provide new insights into the phylogeny of cyprinids. Our study indicated that unpartitioned strategy was optimal for our analyses; partitioned analyses did not provide better-resolved or -supported estimates of cyprinid phylogeny. Bayesian analyses support the following relationships among the major mono- phyletic groups within Cyprinidae： （Cyprininae, Labeoninae）, （（Acheilognathinae, （（Leuciscinae, Tincinae）, Gobioninae））, Xenocyprirlinae）. The placement of Danioninae was poorly resolved. Estimates of divergence dates within the family showed that radiation of the major cyprinid groups occurred during the Late Oligocene through the Late Miocene. Our phylogenetic analyses improved our understanding of the evolutionary history of this important fish family.展开更多
文摘Direction relation is an important spatial relation. Descriptions and representations for direction relations have different levels of detail because of the varying dimensions of spatial objects and different scales of the embedding spaces. Based on a direction- relation matrix, the hierarchical frame of spatial direction relations which partitions direction relations orderly and thoroughly is built. Interior direction relations are used to perfect the representation of direction relations and the binary-encoding idea is creatively applied to construct an interior detailed matrix describing multiple interior direction relations by a uniform matrix. The model integrates topological information into the description model for direction relations, which will lay the foundations of spatial compositive reasoning.
基金We are grateful to the support from the National Natural Science Foundation of China （NSFC） （31425002, 91231205, 81430011, 61303161, 31470220, and 31327001）, and the Frontier Science Research Program, the Soil-Microbe System Function and Regulation Program, and the Science and Technology Service Network Initiative （STS） from the Chinese Academy of Sciences （CAS）.
文摘Method development has always been and will continue to be a core driving force of microbiome science, In this perspective, we argue that in the next decade, method development in microbiome analysis will be driven by three key changes in both ways of thinking and technological platforms： ① a shift from dissecting microbiota structure by sequencing to tracking microbiota state, function, and intercellular interaction via imaging; ② a shift from interrogating a consortium or population of cells to probing individual cells; and ③a shift from microbiome data analysis to microbiome data science. Some of the recent methoddevelopment efforts by Chinese microbiome scientists and their international collaborators that underlie these technological trends are highlighted here. It is our belief that the China Microbiome Initiative has the opportunity to deliver outstanding ＂Made-in-China＂ tools to the international research community, by building an ambitious, competitive, and collaborative program at the forefront of method development for microbiome science.
基金the funding support from the National Natural Science Foundation of China(No.81373702)
文摘For digitalization of traditional Chinese medicine(TCM),research is being conducted on objectivization of diagnosis and treatment,mathematical models of TCM theories,and application of modern information technology to digitize the vast amounts of existing information.However,the author believes that TCM practitioners should first conduct a systematic and comprehensive refined analysis on the knowledge of TCM and unify data elements used in computer intelligence to avoid ambiguity.Thus,we must overcome the epistemological constraints and carefully analyze the relationship among data elements to achieve systematic results and administer TCM appropriately.
文摘The paper study improved K-means algorithm and establish indicators to classify customers according to RFM model. Experimental results show that, the new algorithm has good convergence and stability, it has better than single use of FKP algorithms for clustering. Finally the paper study the application of clustering in customer segmentation of mobile communication enterprise. It discusses the basic theory, customer segmentation methods and steps, the customer segmentation model based on consumption behavior psychology, and the segmentation model is successfully applied to the process of marketing decision support.
文摘The mitochondrial cytochrome b gene was isolated from the caudal fin of Oryzias latipes and PCR was undertaken to determine phylogeny. The nucleotide sequence of the complete cytochrome b gene including the 5＇ and 3＇ ends was 1,143 base pairs （bp） and 1,137 bp encoding 380 and 378 amino acids in the K-11 strain and HS strain, respectively. In addition, higher substitutions both in base and amino acid residues occurred more frequently between the former control （Hd-rR strain） and HS strains than the K-I 1 strain. Approximately similar values in polymorphism, as assessed by restriction endonuclease digestion, were detected when utilizing 20 different enzymes. Therefore, the evolutionary processes were unlikely to involve common ancestors, especially between the K-11 strain and HS strains, in O. latipes populations in Japan. The sequence had been deposited in GenBank Data Base under accession number AB480878 （K-I I strain） and AB480879 （HS strain）.
基金supported by the Natural Science Foundation China under Grant Nos. 10801019 and 10726037
文摘Causation is a distinct concept from association and more important than association inepidemiologic studies.This paper proposes the concept of uniform non-confounding for causal distributioneffects over multiple covariates,and gives the sufficient conditions for uniform non-confoundingover a covariate set C including confounders or non-confounders,and also shows the conditions forconditionally non-confounding in the subpopulations.All these conditions can be tested by observeddata.
基金supported by the National Natural Science Foundation of China (Grant No. 30770300)Chinese Academy of Sciences (Grant No. KSCX2-EW-Q-12)the Cypriniformes Tree of Life Initiative supported by the USA National Science Foundation (Grant No. EF-0431326)
文摘Cyprinidae is the biggest family of freshwater fish, but the phylogenetic relationships among its higher-level taxa are not yet fully resolved. In this study, we used the nuclear recombination activating gene 2 and the mitochondrial 16S ribosomal RNA and cytochrome b genes to reconstruct cyprinid phylogeny. Our aims were to （i） demonstrate the effects of partitioned phylo- genetic analyses on phylogeny reconstruction of cyprinid fishes; （ii） provide new insights into the phylogeny of cyprinids. Our study indicated that unpartitioned strategy was optimal for our analyses; partitioned analyses did not provide better-resolved or -supported estimates of cyprinid phylogeny. Bayesian analyses support the following relationships among the major mono- phyletic groups within Cyprinidae： （Cyprininae, Labeoninae）, （（Acheilognathinae, （（Leuciscinae, Tincinae）, Gobioninae））, Xenocyprirlinae）. The placement of Danioninae was poorly resolved. Estimates of divergence dates within the family showed that radiation of the major cyprinid groups occurred during the Late Oligocene through the Late Miocene. Our phylogenetic analyses improved our understanding of the evolutionary history of this important fish family.
