【目的】随着空间品质研究领域的不断发展和新技术与新数据的引入,公园品质的概念产生了相应的拓展。为厘清和重构公园品质概念内涵,从而进一步推动相关研究在实证层面的发展,需要构建系统性强、覆盖面广的公园品质概念框架。【方法】在...【目的】随着空间品质研究领域的不断发展和新技术与新数据的引入,公园品质的概念产生了相应的拓展。为厘清和重构公园品质概念内涵,从而进一步推动相关研究在实证层面的发展,需要构建系统性强、覆盖面广的公园品质概念框架。【方法】在Web of Science和中国知网中检索并筛选出与公园品质相关的中英文文献,并以此为基础进行文献述评和概念框架构建。【结果】基于现象学的体验概念与环境心理学中人与环境的交互过程理论,将公园体验过程拆解为感觉、知觉和认知3个阶段。依据体验过程各阶段的特点对既往相关研究进行了系统性的梳理,提炼出基于体验过程的公园品质概念框架。【结论】上述框架的建构有助于解决因公园品质概念不明确而导致的测量方法和数据使用混乱的问题,同时兼顾系统性和准确性,以便在不同体验阶段评估公园品质。并且该框架有助于从环境特征要素的完善、环境特征要素组织的优化、环境的可供性的提升、历史文化传承等方面出发,精确制定公园的微观更新策略。展开更多
The progression of next generation sequencing is continuously changing the landscape of genomic, tran- scriptomic, and epigenomic studies. Particularly, advances in single cell manipulation and amplification technique...The progression of next generation sequencing is continuously changing the landscape of genomic, tran- scriptomic, and epigenomic studies. Particularly, advances in single cell manipulation and amplification techniques bring sequencing technology to the single-cell level. Single cell genome sequencing allows us to study tumor evolu- tion, gamete genesis, somatic mosaicism at genome-wide level; single cell transcriptome sequencing unveils the dynamic gene expression during early embryonic devel- opment, differentiation and reprogramming; single cell methylome sequencing is just taking off and shows great potential in cancer and stem cell studies. Lots of attempts are still being made in other dimensions of sequencing. The increasing need for single cell sequencing requires the future techniques with the following features: (1) high accuracy and fidelity; (2) able to perform multiple omics analyses in one cell; (3) high degree of automation and standardized pipeline. These progresses and improvements will lower the barrier for single cell sequencing to enter ordinary laboratories. The wide application of single cell sequencing techniques will substantially change biomedi- cal research in future.展开更多
文摘【目的】随着空间品质研究领域的不断发展和新技术与新数据的引入,公园品质的概念产生了相应的拓展。为厘清和重构公园品质概念内涵,从而进一步推动相关研究在实证层面的发展,需要构建系统性强、覆盖面广的公园品质概念框架。【方法】在Web of Science和中国知网中检索并筛选出与公园品质相关的中英文文献,并以此为基础进行文献述评和概念框架构建。【结果】基于现象学的体验概念与环境心理学中人与环境的交互过程理论,将公园体验过程拆解为感觉、知觉和认知3个阶段。依据体验过程各阶段的特点对既往相关研究进行了系统性的梳理,提炼出基于体验过程的公园品质概念框架。【结论】上述框架的建构有助于解决因公园品质概念不明确而导致的测量方法和数据使用混乱的问题,同时兼顾系统性和准确性,以便在不同体验阶段评估公园品质。并且该框架有助于从环境特征要素的完善、环境特征要素组织的优化、环境的可供性的提升、历史文化传承等方面出发,精确制定公园的微观更新策略。
基金supported by the Recruitment Program of Global Youth Experts to Fan Bai
文摘The progression of next generation sequencing is continuously changing the landscape of genomic, tran- scriptomic, and epigenomic studies. Particularly, advances in single cell manipulation and amplification techniques bring sequencing technology to the single-cell level. Single cell genome sequencing allows us to study tumor evolu- tion, gamete genesis, somatic mosaicism at genome-wide level; single cell transcriptome sequencing unveils the dynamic gene expression during early embryonic devel- opment, differentiation and reprogramming; single cell methylome sequencing is just taking off and shows great potential in cancer and stem cell studies. Lots of attempts are still being made in other dimensions of sequencing. The increasing need for single cell sequencing requires the future techniques with the following features: (1) high accuracy and fidelity; (2) able to perform multiple omics analyses in one cell; (3) high degree of automation and standardized pipeline. These progresses and improvements will lower the barrier for single cell sequencing to enter ordinary laboratories. The wide application of single cell sequencing techniques will substantially change biomedi- cal research in future.