The swelling of SU-8 mold is one of the most important factors influencing the dimensional accuracy of a metal mieropart produced by ultra-violet lithography galvanik abformung（UV-LIGA）. The isolation belt struc- tu...The swelling of SU-8 mold is one of the most important factors influencing the dimensional accuracy of a metal mieropart produced by ultra-violet lithography galvanik abformung（UV-LIGA）. The isolation belt struc- ture is usually employed to enhance the dimensional accuracy of electroformed metal mieropart. However, noble metal is wasted because the isolation belt is filled with metal when noble metal mieroparts are fabricated. There- fore, a semi-isolation belt structure is presented to save noble metal. Furthermore, a high current density is also introduced to shorten the eleetroforming time, and thus the dimensional accuracy of electroformed gold micropart is improved by using the electrolyte jet. The experimental results indicate that both the semi-isolation belt and the high current density can help to enhance the dimensional accuracy of electroformed gold micropart. Its dimen- sional error is only 5 μm at the current density of 0. 6 A/dm2 while the semi-isolation belt structure is used.展开更多
The high temperature liquid is injected into the micro-size capillary and its light propagation behavior is investigated. We focus on two different liquid pumping methods. The first method can pump the high temperatur...The high temperature liquid is injected into the micro-size capillary and its light propagation behavior is investigated. We focus on two different liquid pumping methods. The first method can pump the high temperature liquid tin into the micro-size capillary by using a high pressure difference system. After pumping, a single mode fiber(SMF) connected with the optical carrier based microwave interferometry(OCMI) system is used to measure different liquid tin levels in the micro-size capillary. The second method can pump the room temperature engine oil into the capillary by using a syringe pump. This method can avoid the air bubbles when the liquids are pumped into the capillary.展开更多
Different cell types make up tissues and organs hierarchically and communicate within a complex, three-dimensional (3D) en- vironment. The in vitro recapitulation of tissue-like structures is meaningful, not only for ...Different cell types make up tissues and organs hierarchically and communicate within a complex, three-dimensional (3D) en- vironment. The in vitro recapitulation of tissue-like structures is meaningful, not only for fundamental cell biology research, but also for tissue engineering (TE). Currently, TE research adopts either the top-down or bottom-up approach. The top-down approach involves defining the macroscopic tissue features using biomaterial scaffolds and seeding cells into these scaffolds. Conversely, the bottom-up approach aims at crafting small tissue building blocks with precision-engineered structural and functional microscale features, using physical and/or chemical approaches. The bottom-up strategy takes advantage of the repeating structural and functional units that facilitate cell-cell interactions and cultures multiple cells together as a functional unit of tissue. In this review, we focus on currently available microscale methods that can control mammalian cells to assemble into 3D tissue-like structures.展开更多
基金Supported by the National Natural Science Foundation of China(91023018)~~
文摘The swelling of SU-8 mold is one of the most important factors influencing the dimensional accuracy of a metal mieropart produced by ultra-violet lithography galvanik abformung（UV-LIGA）. The isolation belt struc- ture is usually employed to enhance the dimensional accuracy of electroformed metal mieropart. However, noble metal is wasted because the isolation belt is filled with metal when noble metal mieroparts are fabricated. There- fore, a semi-isolation belt structure is presented to save noble metal. Furthermore, a high current density is also introduced to shorten the eleetroforming time, and thus the dimensional accuracy of electroformed gold micropart is improved by using the electrolyte jet. The experimental results indicate that both the semi-isolation belt and the high current density can help to enhance the dimensional accuracy of electroformed gold micropart. Its dimen- sional error is only 5 μm at the current density of 0. 6 A/dm2 while the semi-isolation belt structure is used.
基金supported by the U.S.Department of Energy,National Energy Technology Laboratory,Morgantown,WV,USA(No.DEFE0012272)the Joint Funds(NSFC-Henan)of the National Natural Science Foundation of China(No.U1204615)
文摘The high temperature liquid is injected into the micro-size capillary and its light propagation behavior is investigated. We focus on two different liquid pumping methods. The first method can pump the high temperature liquid tin into the micro-size capillary by using a high pressure difference system. After pumping, a single mode fiber(SMF) connected with the optical carrier based microwave interferometry(OCMI) system is used to measure different liquid tin levels in the micro-size capillary. The second method can pump the room temperature engine oil into the capillary by using a syringe pump. This method can avoid the air bubbles when the liquids are pumped into the capillary.
基金supported by Ministry of Science and Technology of China(Grant Nos.2009CB930001 and 2011CB933201)Chinese Academy ofSciences(Grant No.KJCX2-YW-M15)the National Natural ScienceFoundation of China(Grant Nos.20890020,90813032,21025520 and 51073045)
文摘Different cell types make up tissues and organs hierarchically and communicate within a complex, three-dimensional (3D) en- vironment. The in vitro recapitulation of tissue-like structures is meaningful, not only for fundamental cell biology research, but also for tissue engineering (TE). Currently, TE research adopts either the top-down or bottom-up approach. The top-down approach involves defining the macroscopic tissue features using biomaterial scaffolds and seeding cells into these scaffolds. Conversely, the bottom-up approach aims at crafting small tissue building blocks with precision-engineered structural and functional microscale features, using physical and/or chemical approaches. The bottom-up strategy takes advantage of the repeating structural and functional units that facilitate cell-cell interactions and cultures multiple cells together as a functional unit of tissue. In this review, we focus on currently available microscale methods that can control mammalian cells to assemble into 3D tissue-like structures.
