Subcorneal pustular dermatosis (SCPD) is an uncommon disorder, characterized by a chronic relapsing vesiculopustular eruption, mainly involving the trunk and intertriginous areas, and usually seen in women > 40 yea...Subcorneal pustular dermatosis (SCPD) is an uncommon disorder, characterized by a chronic relapsing vesiculopustular eruption, mainly involving the trunk and intertriginous areas, and usually seen in women > 40 years old. Various therapies have been reported to be effective in treating SCPD, such as dapsone, systemic glucocorticoids, acitretin, etretinate, infliximab and phototherapy. We report a case of a 54- year- old woman affected by SCPD who after failure of different therapies showed a dramatic but only temporary improvement of her disease during a cycle of therapy with infliximab. In addition, an array of cytokines was simultaneously measured in suction blister fluids obtained from involved or uninvolved skin at various time intervals during the first 12 weeks of observation.展开更多
Postoperative pain management may modulate the level of cytokine such as IL-2、IL-6、TNF-α,etc.The analgesic techniques include epidural analgesia,intravenous analgesia,multimodal analgesia and preemptive analgesia.T...Postoperative pain management may modulate the level of cytokine such as IL-2、IL-6、TNF-α,etc.The analgesic techniques include epidural analgesia,intravenous analgesia,multimodal analgesia and preemptive analgesia.This review outlines the function of cytokines in the postoperative pain and the effect of different analgesic method on cytokine production in the postoperative period.展开更多
文摘Subcorneal pustular dermatosis (SCPD) is an uncommon disorder, characterized by a chronic relapsing vesiculopustular eruption, mainly involving the trunk and intertriginous areas, and usually seen in women > 40 years old. Various therapies have been reported to be effective in treating SCPD, such as dapsone, systemic glucocorticoids, acitretin, etretinate, infliximab and phototherapy. We report a case of a 54- year- old woman affected by SCPD who after failure of different therapies showed a dramatic but only temporary improvement of her disease during a cycle of therapy with infliximab. In addition, an array of cytokines was simultaneously measured in suction blister fluids obtained from involved or uninvolved skin at various time intervals during the first 12 weeks of observation.
文摘Postoperative pain management may modulate the level of cytokine such as IL-2、IL-6、TNF-α,etc.The analgesic techniques include epidural analgesia,intravenous analgesia,multimodal analgesia and preemptive analgesia.This review outlines the function of cytokines in the postoperative pain and the effect of different analgesic method on cytokine production in the postoperative period.
