Objective:To study the inhibitory effect of docetaxel(DOC),oxaliplatin(OXA) and their combination on proliferation of cervical cancer line HeLa.Methods:Cell morphological changes were observed by inverted phase contra...Objective:To study the inhibitory effect of docetaxel(DOC),oxaliplatin(OXA) and their combination on proliferation of cervical cancer line HeLa.Methods:Cell morphological changes were observed by inverted phase contrast microscope,cell inhibition rates in different groups were examined by MTT,and cell cycle and apoptosis rates were determined by flow cytometry(FCM).Results:DOC and OXA inhibited the proliferation of cervical cancer cell line HeLa in a dose-dependent,and combination of the two drugs had an enhanced inhibitory effect;the apoptosis rate was also significantly increased when the two drugs were used in combination.Conclusion:DOC and OXA can synergistically inhibit the proliferation of cervical cancer cell line HeLa,which indicates that combination of the two drugs might has a promising future for clinical treatment of cervical cancer.展开更多
Cassava peel has a lot of nutrients which can be utilized as fertilizer in agriculture. However, high cellulose contents may cause difficulty for organic digestion and slow down the nutrient absorption for plants. Thi...Cassava peel has a lot of nutrients which can be utilized as fertilizer in agriculture. However, high cellulose contents may cause difficulty for organic digestion and slow down the nutrient absorption for plants. This study aims to reach the microorganisms or their combination for biodegradating the cassava peel waste. The initial result shows that after 21 days the glucose concentration in all samples was the highest during experiment times. The reducing glucose produced in mg/mL by the selected bacteria was 9.32, higher than the selected fungie of 1.57 mg/mL. The percentage degradation of cassava peel weigh was the highest for fungi which was 52% of weigh, respectively. Meanwhile, bacteria only degradated about 31.6% after 4 weeks. However, the combination between bacteria and fungi provides the highest glucose concentration, 19.29 mg/mL and digests 62% of the mass cassava in experiment. This study suggests that biodegradation of agro-wastes in the environment to reduce biomass waste pollution is very promising.展开更多
文摘Objective:To study the inhibitory effect of docetaxel(DOC),oxaliplatin(OXA) and their combination on proliferation of cervical cancer line HeLa.Methods:Cell morphological changes were observed by inverted phase contrast microscope,cell inhibition rates in different groups were examined by MTT,and cell cycle and apoptosis rates were determined by flow cytometry(FCM).Results:DOC and OXA inhibited the proliferation of cervical cancer cell line HeLa in a dose-dependent,and combination of the two drugs had an enhanced inhibitory effect;the apoptosis rate was also significantly increased when the two drugs were used in combination.Conclusion:DOC and OXA can synergistically inhibit the proliferation of cervical cancer cell line HeLa,which indicates that combination of the two drugs might has a promising future for clinical treatment of cervical cancer.
文摘Cassava peel has a lot of nutrients which can be utilized as fertilizer in agriculture. However, high cellulose contents may cause difficulty for organic digestion and slow down the nutrient absorption for plants. This study aims to reach the microorganisms or their combination for biodegradating the cassava peel waste. The initial result shows that after 21 days the glucose concentration in all samples was the highest during experiment times. The reducing glucose produced in mg/mL by the selected bacteria was 9.32, higher than the selected fungie of 1.57 mg/mL. The percentage degradation of cassava peel weigh was the highest for fungi which was 52% of weigh, respectively. Meanwhile, bacteria only degradated about 31.6% after 4 weeks. However, the combination between bacteria and fungi provides the highest glucose concentration, 19.29 mg/mL and digests 62% of the mass cassava in experiment. This study suggests that biodegradation of agro-wastes in the environment to reduce biomass waste pollution is very promising.