This paper describes theoretical steps to develop an optical nanobiosensor using bacteriorhodopsin （BR） as the biomembrane and Single-Walled Carbon NanoTube （SWCNT） as the scaffold. Bacteriorhodopsin is a retinal ...This paper describes theoretical steps to develop an optical nanobiosensor using bacteriorhodopsin （BR） as the biomembrane and Single-Walled Carbon NanoTube （SWCNT） as the scaffold. Bacteriorhodopsin is a retinal protein used by archaea that come under the family of halobacteria. This retinal protein acts as a proton pump and resulting proton gradient is used to change the voltage that pass across the drain and source. The biosensor contains nano ISFET where the channel is made of a carbon nanotube for the conduction of current. The gate is replaced by bacteriorhodopsin biomembrane. Bacteriorhodopsin can be used as a molecular-level ultra fast bi-stable red / green photo switch for making 3D optical molecular memories that reliably store data with 10,000 molecules/bit. The molecules switch in femtoseconds. Biomembrane will sense 510 nm and 650 nm wavelength of light and the sensing voltage can be used to convert the data into digital signals. This molecular level memory device can be used for ‘Read-Write＇ operations. The sensor performance will also be ultra fast since it uses photons for the data storage, which are much faster than electrons used in normal memory devices, and the 3D storage capacity is much higher maximum of 10^13/cm^2.展开更多
Bacteriorhodopsin (BR) is a photochromic membrane protein isolated from a strain of halobacteria.Embedment of BR into a polymeric matrix enables the application of the photoactive protein as an optical material.In thi...Bacteriorhodopsin (BR) is a photochromic membrane protein isolated from a strain of halobacteria.Embedment of BR into a polymeric matrix enables the application of the photoactive protein as an optical material.In this work,a chemically crosslinked BR/gelatin film was prepared.The cross-linked film was found to be highly stable even under extreme alkaline or detergent circumstance while BR maintained its bioactivity.The treatments of base and detergents also led to dramatic prolongation of the lifetime of M photoproduct,which might be beneficial for potential applications such as information storage.The BR/gelatin film was demonstrated to tentatively record a simple pattern.展开更多
文摘This paper describes theoretical steps to develop an optical nanobiosensor using bacteriorhodopsin （BR） as the biomembrane and Single-Walled Carbon NanoTube （SWCNT） as the scaffold. Bacteriorhodopsin is a retinal protein used by archaea that come under the family of halobacteria. This retinal protein acts as a proton pump and resulting proton gradient is used to change the voltage that pass across the drain and source. The biosensor contains nano ISFET where the channel is made of a carbon nanotube for the conduction of current. The gate is replaced by bacteriorhodopsin biomembrane. Bacteriorhodopsin can be used as a molecular-level ultra fast bi-stable red / green photo switch for making 3D optical molecular memories that reliably store data with 10,000 molecules/bit. The molecules switch in femtoseconds. Biomembrane will sense 510 nm and 650 nm wavelength of light and the sensing voltage can be used to convert the data into digital signals. This molecular level memory device can be used for ‘Read-Write＇ operations. The sensor performance will also be ultra fast since it uses photons for the data storage, which are much faster than electrons used in normal memory devices, and the 3D storage capacity is much higher maximum of 10^13/cm^2.
基金supported by the National Basic Research Rrogram of China (973 Program,2009CB930000)National Natural Science Foundation of China (21034002)
文摘Bacteriorhodopsin (BR) is a photochromic membrane protein isolated from a strain of halobacteria.Embedment of BR into a polymeric matrix enables the application of the photoactive protein as an optical material.In this work,a chemically crosslinked BR/gelatin film was prepared.The cross-linked film was found to be highly stable even under extreme alkaline or detergent circumstance while BR maintained its bioactivity.The treatments of base and detergents also led to dramatic prolongation of the lifetime of M photoproduct,which might be beneficial for potential applications such as information storage.The BR/gelatin film was demonstrated to tentatively record a simple pattern.
