Objectives:To investigate the current situation of palliative care needs and the symptom burden in patients with end-stage renal disease(ESRD)undergoing maintenance hemodialysis(MHD),and to explore whether there are d...Objectives:To investigate the current situation of palliative care needs and the symptom burden in patients with end-stage renal disease(ESRD)undergoing maintenance hemodialysis(MHD),and to explore whether there are differences between younger and older patients.Methods:This cross-sectional study was conducted in the hemodialysis centers of two tertiary hospitals from November 2021 to June 2022.Participants were selected by convenience sampling.Sociodemographics,clinical characteristics,the Palliative Care Outcome Scale(POS),the Dialysis Symptom Index(DSI),and health-related quality of life(EQ-5D-3L)were used for evaluation.Descriptive statistics,between-group comparisons,and correlation analysis were used to analyze the data.Results:A total of 236 patients were enrolled,including 118 younger and 118 older patients.The total median(P25,P75)POS score was 16.0(12.0,23.0),and the score was higher in older patients(P<0.01).The mean total number of symptoms in MHD patients was 15.04±5.06,and the overall median symptom severity score was 59.0(52.0,71.0);these scores were higher in the older group(P<0.01).The most common symptom was dry mouth(91.5%),followed by itching(83.1%),and dry skin(82.2%).Additionally,palliative care needs were significantly associated with symptom burden and health-related quality of life(HRQOL).Conclusions:The results showed that patients with ESRD undergoing MHD have a significant symptom burden and moderate palliative care needs,which are more severe in older patients.Therefore,interdisciplinary teams should be formed to actively manage patients’symptoms and meet the physical,psychological,social,and spiritual needs related to palliative care to improve patients’HRQOL.展开更多
The cultivar date Lemsi is well known in the coastal oasis of Tunisia for both its quality stage ＂blah＂ and its earliness. This variety is characterized by its astringent taste and has never been studied extensively...The cultivar date Lemsi is well known in the coastal oasis of Tunisia for both its quality stage ＂blah＂ and its earliness. This variety is characterized by its astringent taste and has never been studied extensively. An osmotic dehydration treatment is necessary to improve the quality of the final product for maintaining its integrity. Thus, it is a preservation technique that is often used as pretreatment to obtain partially dehydrated fruit. In this experimental study, the cultivar date Lemsi were cut into cubes of 1 cm3 and were immersed in sucrose solutions of 50%, 60% and 70% at 20℃ for 0-240 min. The moisture content, the solute gain, the water loss and the ratio WL/SG are determined and discussed. The results deduced from this work have showed that sugar gain SG, water loss WL and the ratio WL/SG are increased with concentration of osmotic solution. Likewise, the osmotic dehydration treatment need to be followed of a convective drying to ensure the quality of the final product.展开更多
Hypertension is believed to be a major risk factor that causes cardiovascular disease in patients on hemodialysis （HD）. Removing of excess water during HD, accurate assessment of dry weight and anti-hypertension the...Hypertension is believed to be a major risk factor that causes cardiovascular disease in patients on hemodialysis （HD）. Removing of excess water during HD, accurate assessment of dry weight and anti-hypertension therapeutics are the most com- monly used measures to lower blood pressure in patients on HD.展开更多
Objective To explore the effective therapy for deficiency syndrome in the maintenance hemodialysis patients of end-stage renal disease. Methods Ninety-seven maintenance hemodialysis patients of end-stage renal disease...Objective To explore the effective therapy for deficiency syndrome in the maintenance hemodialysis patients of end-stage renal disease. Methods Ninety-seven maintenance hemodialysis patients of end-stage renal disease were divided into an observation group （51 cases） and a control group （46 cases） randomly, and routine western medicines were used in both groups. On this base, moxibustion was given at Zusanli （足三里 ST 36） and Sanyijiao （三阴交 SP 6） with a paper-tube-moxibustion equipment in the observation group. The therapeutic effects on syndromes were evaluated by comparing the symptom scores in two groups before and after treatment. Results After treatment, all the symptom scores in the observation group were improved significantly （all P〈0.05）, with fatigue and weakness, short breath and aversion to talking, poor appetite, lassitude in loin and knees, aversion to cold, cool extremities and so on most obviously improved, and the total effective rate on the syndrome in observation group （64.7%, 33/51） was significantly higher than that in control group （23.9%, 11/46）, with a significant difference between the two groups （P〈0.05）. Conclusion Moxibustion can improve the clinical symptoms of maintenance hemodialysis patients of end-stage renal disease, and it has some therapeutic effect on the deficiency syndrome.展开更多
文摘Objectives:To investigate the current situation of palliative care needs and the symptom burden in patients with end-stage renal disease(ESRD)undergoing maintenance hemodialysis(MHD),and to explore whether there are differences between younger and older patients.Methods:This cross-sectional study was conducted in the hemodialysis centers of two tertiary hospitals from November 2021 to June 2022.Participants were selected by convenience sampling.Sociodemographics,clinical characteristics,the Palliative Care Outcome Scale(POS),the Dialysis Symptom Index(DSI),and health-related quality of life(EQ-5D-3L)were used for evaluation.Descriptive statistics,between-group comparisons,and correlation analysis were used to analyze the data.Results:A total of 236 patients were enrolled,including 118 younger and 118 older patients.The total median(P25,P75)POS score was 16.0(12.0,23.0),and the score was higher in older patients(P<0.01).The mean total number of symptoms in MHD patients was 15.04±5.06,and the overall median symptom severity score was 59.0(52.0,71.0);these scores were higher in the older group(P<0.01).The most common symptom was dry mouth(91.5%),followed by itching(83.1%),and dry skin(82.2%).Additionally,palliative care needs were significantly associated with symptom burden and health-related quality of life(HRQOL).Conclusions:The results showed that patients with ESRD undergoing MHD have a significant symptom burden and moderate palliative care needs,which are more severe in older patients.Therefore,interdisciplinary teams should be formed to actively manage patients’symptoms and meet the physical,psychological,social,and spiritual needs related to palliative care to improve patients’HRQOL.
文摘The cultivar date Lemsi is well known in the coastal oasis of Tunisia for both its quality stage ＂blah＂ and its earliness. This variety is characterized by its astringent taste and has never been studied extensively. An osmotic dehydration treatment is necessary to improve the quality of the final product for maintaining its integrity. Thus, it is a preservation technique that is often used as pretreatment to obtain partially dehydrated fruit. In this experimental study, the cultivar date Lemsi were cut into cubes of 1 cm3 and were immersed in sucrose solutions of 50%, 60% and 70% at 20℃ for 0-240 min. The moisture content, the solute gain, the water loss and the ratio WL/SG are determined and discussed. The results deduced from this work have showed that sugar gain SG, water loss WL and the ratio WL/SG are increased with concentration of osmotic solution. Likewise, the osmotic dehydration treatment need to be followed of a convective drying to ensure the quality of the final product.
文摘Hypertension is believed to be a major risk factor that causes cardiovascular disease in patients on hemodialysis （HD）. Removing of excess water during HD, accurate assessment of dry weight and anti-hypertension therapeutics are the most com- monly used measures to lower blood pressure in patients on HD.
基金Supported by the second lot TCM superior diseases clinical research items of China Academy of Chinese Medical Sciences: CACMS07Y0019
文摘Objective To explore the effective therapy for deficiency syndrome in the maintenance hemodialysis patients of end-stage renal disease. Methods Ninety-seven maintenance hemodialysis patients of end-stage renal disease were divided into an observation group （51 cases） and a control group （46 cases） randomly, and routine western medicines were used in both groups. On this base, moxibustion was given at Zusanli （足三里 ST 36） and Sanyijiao （三阴交 SP 6） with a paper-tube-moxibustion equipment in the observation group. The therapeutic effects on syndromes were evaluated by comparing the symptom scores in two groups before and after treatment. Results After treatment, all the symptom scores in the observation group were improved significantly （all P〈0.05）, with fatigue and weakness, short breath and aversion to talking, poor appetite, lassitude in loin and knees, aversion to cold, cool extremities and so on most obviously improved, and the total effective rate on the syndrome in observation group （64.7%, 33/51） was significantly higher than that in control group （23.9%, 11/46）, with a significant difference between the two groups （P〈0.05）. Conclusion Moxibustion can improve the clinical symptoms of maintenance hemodialysis patients of end-stage renal disease, and it has some therapeutic effect on the deficiency syndrome.
