Objective:To observe the clinical effect of acupuncture plus rehabilitation training in treating early-stage shoulder-hand syndrome due to ischemic stroke.Methods:Sixty patients were randomized into an observation g...Objective:To observe the clinical effect of acupuncture plus rehabilitation training in treating early-stage shoulder-hand syndrome due to ischemic stroke.Methods:Sixty patients were randomized into an observation group and a control group,30 in each.The observation group was intervened by acupuncture plus rehabilitation training,and the control group only received rehabilitation training.After 3 treatment courses,the scores of visual analogue scale (VAS) and Fugl-Meyer assessment scale (FMA),and the clinical effect were compared between the two groups.Results:The two groups both obtained significant improvements in VAS and FMA scores after treatment (P〈0.05 or P〈0.01).After treatment,it showed marked differences in comparing VAS and FMA scores between the observation group and the control group (P〈0.05).The total effective rate was 86.7% in the observation group,versus 63.3% in the control group,and the difference was statistically significant (P〈0.05).Conclusion:The result of acupuncture plus rehabilitation training in treating early-stage shoulder-hand syndrome due to ischemic stroke is superior to rehabilitation training alone.展开更多
Objective:To observe the effect of point-through-point needling combined with tuina for shoulder-hand syndrome after stroke.Methods:Eighty-six cases with post-stroke shoulder-hand syndrome were randomly divided into...Objective:To observe the effect of point-through-point needling combined with tuina for shoulder-hand syndrome after stroke.Methods:Eighty-six cases with post-stroke shoulder-hand syndrome were randomly divided into an observation group and a control group,43 cases in each group.Patients in the observation group were treated by point-through-point needling combined with tuina therapy on the basis of the conventional treatment;while patients in the control group were treated by tuina therapy on the basis of conventional therapy.Six treatments constitute a course,and the efficacy was evaluated after 4 courses.Results:The total effective rate was 88.4% in the observation group,and it was 69.8% in the control group.And the comparison indicated that the observation group had a more efficient result than the control group did (χ 2 =4.497,P〈0.05).The scores of visual analogue scale (VAS) and Fugl-Meyer assessment (FMA) were significantly improved after treatments in both groups (P〈0.05 or P〈0.01).After treatment,the scores of VAS and FMA of the observation group were significantly different from that in the control group (P〈0.05).Conclusion:Because of the efficacy,point-through-point needling combined with tuina therapy for shoulder-hand syndrome after stroke is certainly worthy of further study,and can be used in clinical practice.展开更多
Objective: To observe the differences in analgesic effect of moxibustion at different intervention times on dysmenorrhea rats and explore its effect mechanism.Methods: Forty-five female Wistar rats were randomly div...Objective: To observe the differences in analgesic effect of moxibustion at different intervention times on dysmenorrhea rats and explore its effect mechanism.Methods: Forty-five female Wistar rats were randomly divided into blank control group(group A), model group(group B), pre-moxibustion group(group C), instant moxibustion group(group D) and pre-instant moxibustion group(group E),with 9 rats in each group. Cold-damp coagulation and stagnation type dysmenorrhea models were established. In group C,mild moxibustion on "Shenque(神阙 CV 8) " and"Guanyuan(关元 CV 4)" was carried out from the time after modeling on the 8 th day for 3 consecutive days. In group D, mild moxibustion was given as the same methods with group C after injection with oxytocin on the 11 th day. In group E, mild moxibustion was given as the same methods from the time after modeling on the 8 th day to that after injection with oxytocin on the 11 th day for 4 consecutive days. The writhing behavior and the changes in levels of ET-1 and NO in uterine tissues of rats with dysmenorrhea in each group were observed.Results: Comparison of the latent period: compared with(4.38 ± 1.06) min in group B,the latent period of rats in group C(9.67 ± 1.32) min,group D(11.78 ± 1.30) min and group E(15.00 ± 1.22) min obviously prolonged(all p 0.01). Compared with group C, the latent period of group E obviously prolonged(p 0.01). Compared with group D, the latent period of group E obviously prolonged(p 0.01).Comparison of the writhing times: compared with(4.38 ± 1.06) in group B,the writhing times of rats in group C(9.67 ± 1.32),group D(11.78 ± 1.30) and group E(15.00 ± 1.22) reduced(all p 0.01). Compared with group C,the writhing times of rats in group D and group E reduced(both p 0.01). Compared with group D, the writhing times in group E reduced(p 0.05). Comparison of the total writhing score:compared with(4.38 ± 1.06) in group B,the total writhing score of rats in group C(9.67±1.32),group D(11.78 ± 1.30) and group E(15.00 ± 1.22) decreased(all p 0.01). Compared with group C,the total writhing score of rats in group D and group E decreased(both p 0.01). Compared with group D,the total writhing score of rats in group E decreased(p 0.05). Comparison of ET-1 level: compared with(4.80 ± 0.47) in group A,the ET-1 level in uterine tissues of rats in group B(7.57±0.69) significantly increased(P 0.01). Compared with group B, the ET-1 level in uterine tissues of rats in group C(6.20 ±0.50),group D(5.67 ±0.29) and group E(5.16±0.33) obviously decreased(all p 0.01). Compared with group C, the ET-1 level in uterine tissues of rats in group D and group E obviously decreased(p 0.05, p 0.01). Compared with group D, the ET-1 level in uterine tissues of rats in group Eobviously decreased(p 0.05). Comparison of NO level: compared with(6.63±1.83) in group A, the NO level in uterine tissues of rats in group B(1.62 ±0.58) significantly decreased(p 0.01). Compared with group B, the NO level in uterine tissues of rats in group C(3.60±0.59),group D(4.77 ±0.67) and group E(5.99±0.63) obviously increased(all p 0.01). Compared with group C,the NO level in uterine tissues of rats in group Dand group E obviously increased(p 0.05, p 0.01). Compared with group D, the NO level in uterine tissues of rats in group E obviously increased(p 0.01).Conclusion: The analgesic effect of mild moxibustion at different intervention times on cold-damp coagulation and stagnation type dysmenorrhea rats was different, which was the most significant in pre-instant moxibustion group. One of the mechanisms of action may be related with the adjustment of abnormal levels of ET-1 and NO.展开更多
文摘Objective:To observe the clinical effect of acupuncture plus rehabilitation training in treating early-stage shoulder-hand syndrome due to ischemic stroke.Methods:Sixty patients were randomized into an observation group and a control group,30 in each.The observation group was intervened by acupuncture plus rehabilitation training,and the control group only received rehabilitation training.After 3 treatment courses,the scores of visual analogue scale (VAS) and Fugl-Meyer assessment scale (FMA),and the clinical effect were compared between the two groups.Results:The two groups both obtained significant improvements in VAS and FMA scores after treatment (P〈0.05 or P〈0.01).After treatment,it showed marked differences in comparing VAS and FMA scores between the observation group and the control group (P〈0.05).The total effective rate was 86.7% in the observation group,versus 63.3% in the control group,and the difference was statistically significant (P〈0.05).Conclusion:The result of acupuncture plus rehabilitation training in treating early-stage shoulder-hand syndrome due to ischemic stroke is superior to rehabilitation training alone.
文摘Objective:To observe the effect of point-through-point needling combined with tuina for shoulder-hand syndrome after stroke.Methods:Eighty-six cases with post-stroke shoulder-hand syndrome were randomly divided into an observation group and a control group,43 cases in each group.Patients in the observation group were treated by point-through-point needling combined with tuina therapy on the basis of the conventional treatment;while patients in the control group were treated by tuina therapy on the basis of conventional therapy.Six treatments constitute a course,and the efficacy was evaluated after 4 courses.Results:The total effective rate was 88.4% in the observation group,and it was 69.8% in the control group.And the comparison indicated that the observation group had a more efficient result than the control group did (χ 2 =4.497,P〈0.05).The scores of visual analogue scale (VAS) and Fugl-Meyer assessment (FMA) were significantly improved after treatments in both groups (P〈0.05 or P〈0.01).After treatment,the scores of VAS and FMA of the observation group were significantly different from that in the control group (P〈0.05).Conclusion:Because of the efficacy,point-through-point needling combined with tuina therapy for shoulder-hand syndrome after stroke is certainly worthy of further study,and can be used in clinical practice.
基金Supported by Youth fund project of Hebei Education Department:QN2015027scientific project supported by Administration of Traditional Chinese Medicine of Hebei Province:2015089scientific program supported by Hebei Provincial Science and Technology Department:152777143~~
文摘Objective: To observe the differences in analgesic effect of moxibustion at different intervention times on dysmenorrhea rats and explore its effect mechanism.Methods: Forty-five female Wistar rats were randomly divided into blank control group(group A), model group(group B), pre-moxibustion group(group C), instant moxibustion group(group D) and pre-instant moxibustion group(group E),with 9 rats in each group. Cold-damp coagulation and stagnation type dysmenorrhea models were established. In group C,mild moxibustion on "Shenque(神阙 CV 8) " and"Guanyuan(关元 CV 4)" was carried out from the time after modeling on the 8 th day for 3 consecutive days. In group D, mild moxibustion was given as the same methods with group C after injection with oxytocin on the 11 th day. In group E, mild moxibustion was given as the same methods from the time after modeling on the 8 th day to that after injection with oxytocin on the 11 th day for 4 consecutive days. The writhing behavior and the changes in levels of ET-1 and NO in uterine tissues of rats with dysmenorrhea in each group were observed.Results: Comparison of the latent period: compared with(4.38 ± 1.06) min in group B,the latent period of rats in group C(9.67 ± 1.32) min,group D(11.78 ± 1.30) min and group E(15.00 ± 1.22) min obviously prolonged(all p 0.01). Compared with group C, the latent period of group E obviously prolonged(p 0.01). Compared with group D, the latent period of group E obviously prolonged(p 0.01).Comparison of the writhing times: compared with(4.38 ± 1.06) in group B,the writhing times of rats in group C(9.67 ± 1.32),group D(11.78 ± 1.30) and group E(15.00 ± 1.22) reduced(all p 0.01). Compared with group C,the writhing times of rats in group D and group E reduced(both p 0.01). Compared with group D, the writhing times in group E reduced(p 0.05). Comparison of the total writhing score:compared with(4.38 ± 1.06) in group B,the total writhing score of rats in group C(9.67±1.32),group D(11.78 ± 1.30) and group E(15.00 ± 1.22) decreased(all p 0.01). Compared with group C,the total writhing score of rats in group D and group E decreased(both p 0.01). Compared with group D,the total writhing score of rats in group E decreased(p 0.05). Comparison of ET-1 level: compared with(4.80 ± 0.47) in group A,the ET-1 level in uterine tissues of rats in group B(7.57±0.69) significantly increased(P 0.01). Compared with group B, the ET-1 level in uterine tissues of rats in group C(6.20 ±0.50),group D(5.67 ±0.29) and group E(5.16±0.33) obviously decreased(all p 0.01). Compared with group C, the ET-1 level in uterine tissues of rats in group D and group E obviously decreased(p 0.05, p 0.01). Compared with group D, the ET-1 level in uterine tissues of rats in group Eobviously decreased(p 0.05). Comparison of NO level: compared with(6.63±1.83) in group A, the NO level in uterine tissues of rats in group B(1.62 ±0.58) significantly decreased(p 0.01). Compared with group B, the NO level in uterine tissues of rats in group C(3.60±0.59),group D(4.77 ±0.67) and group E(5.99±0.63) obviously increased(all p 0.01). Compared with group C,the NO level in uterine tissues of rats in group Dand group E obviously increased(p 0.05, p 0.01). Compared with group D, the NO level in uterine tissues of rats in group E obviously increased(p 0.01).Conclusion: The analgesic effect of mild moxibustion at different intervention times on cold-damp coagulation and stagnation type dysmenorrhea rats was different, which was the most significant in pre-instant moxibustion group. One of the mechanisms of action may be related with the adjustment of abnormal levels of ET-1 and NO.