仲景经方命名演变规律解析

目的:探讨仲景经方的命名形式及其演变规律。方法:参考《伤寒论》《金匮要略》《辅行诀脏腑用药法要》中的文献资料,比较相关经方的联系,厘清不同命名方法出现的先后。结果:仲景经方的命名方式虽不外乎根据药物组成、功效、主治而命名,但为了应用与传播的便利,发生了由全部药味到少数主药、由药味构成到功效主治、由不分大小到区分大小、由名实相副到名实不副的演变过程。结论:这一探讨不仅起到了正本清源的作用,而且也从方名演变角度揭示了整个仲景经方家族逐步发展成熟的过程。文中所涉承气类方、四逆类方、真武类方、柴胡类方、麻黄类方、泻心类方等临床常用经方,可为相关研究者提供参考。

《金匮要略》脏腑气逆证治探究

文章着重探讨了《金匮要略》中有关脏腑气逆证治的部分,以脏腑为纲,具体分为肺气上逆之喘咳、胃气上逆之呕哕、肝气上逆之肝气奔豚、肾气上逆之奔豚以及阳微阴弦之胸痹等证。通过分析条文所述证治,探究其病因、病机与证治特点。通过分析原书所记载方药的组成、用量、功用以及与病机之间的联系,总结《金匮要略》在脏腑气逆治疗中的遣方用药规律。从《金匮要略》治疗脏腑气逆证的诸多药物中提炼出常用药半夏、桂枝、生姜,通过结合其功用、主治以及一些医家观点,揭示它们在相应脏腑气逆证治中的应用规律。

Research on Herb Pairs of Classical Formulae of ZHANG ZhongJing Using Big Data Technology

Objective To analyze various herbal combinations in Treatise on Exogenous Febrile Diseases(Shang Han Lun,《伤寒论》)and Synopsis of Prescriptions of the Golden Chamber(Jin Gui Yao Lve,《金匮要略》),seeking to identify fundamental rules dictating the selection of herbal combinations through probability models and big data technology.Methods A total of 252 formulae were collected from Treatise on Exogenous Febrile Diseases(Shang Han Lun,《伤寒论》)and Synopsis of Prescriptions of the Golden Chamber(Jin Gui Yao Lve,《金匮要略》)by ZHANG Zhong-Jing.Formulae were then preprocessed with all herb names standardized.The concepts of candidate herb pair and candidate herb pair probability were proposed to analyze the rules of combinations in classical formulae based on probability statistics.MapReduce parallel computing framework of distributed big data technology was adopted to analyze large data samples combined with inverted index algorithm.Results The results showed that the core herbs were Glycyrrhizae Radix Rhizoma(Gan Cao,甘草),Cinnamomi Ramulus(Gui Zhi,桂枝),Zingiberis Rhizoma Recens(Sheng Jiang,生姜),Jujubae Fructus(Da Zao,大枣),Paeoniae Radix Alba(Bai Shao,白芍),etc.43 high-frequency pairs co-occurring 10 times or above were extracted,and 35 of these combinations were recognized as traditional herb pairs,such as Cinnamomi Ramulus(Gui Zhi,桂枝)-Glycyrrhizae Radix Rhizoma(Gan Cao,甘草),Zingiberis Rhizoma Recens(Sheng Jiang,生姜)-Jujubae Fructus(Da Zao,大枣),and Cinnamomi Ramulus(Gui Zhi,桂枝)-Ginseng Radix Et Rhizoma(Ren Shen,人参).The other 8 pairs of combinations,such as Paeoniae Radix Alba(Bai Shao,白芍)-Zingiberis Rhizoma Recens(Sheng Jiang,生姜),Paeoniae Radix Alba(Bai Shao,白芍)-Jujubae Fructus(Da Zao,大枣),and Zingiberis Rhizoma Recens(Sheng Jiang,生姜)-Ginseng Radix Et Rhizoma(Ren Shen,人参),were not defined traditionally,but in connection with commonly used herbs.Classical formulae took the core herbs as principles,focusing on tonifying deficiency,strengthening the spleen and the stomach,strengthening the healthy Qi,and eliminating pathogenic factors.The compatibility pattern of properties involved was mainly acrid and sweet,which reflected the compatibility laws of benefiting Qi and tonifying Yang,replenishing Qi and nourishing blood,etc.Conclusions The research of classical formulae provides common understanding of some basic rules that have been adopted to tackle common illnesses/diseases using herbal medicine.The results help to reinforce theoretical understanding and development of traditional Chinese medicine(TCM),and revealing the hidden rules of combination in TCM data.Analyzing wider data samples of various herbal combinations through computation and big data technology can further optimize the use of TCM.

经方配伍术数机制研究方法

《伤寒论》组方术数机制是中医理论与临床研究中十分吸引人却难得其要旨的领域。引入复数概念,解读中医术数机制,通过复数建立以药物、剂量、煎服法等为变量的术数配伍矩阵,结合临床经验田野研究,探索经方配伍规律术数原理及运算法则。

《伤寒论》太阳病常用方归经量化

目的:研究太阳病常用方归经量化特点、规律。方法:以中医方剂归经量化模型体系为支撑,应用中医方剂归经量化计算机辨析系统,对太阳病常用方进行归经量化辨析。结果:将《伤寒论》太阳病常用方按照第一归经、功效及类方分类进行归经量化研究,初步探析了《伤寒论》太阳病常用方归经思想及其应用特点,并验证了中医方药归经量化辨析系统与传统太阳病方药归经认识基本吻合。结论:本研究通过纵向和横向分析太阳病常用方归经顺序差异、强度大小,实现了太阳病单经归经量化辨析。