Objective： To observe the clinical effect of electroacupuncture in treating perimenopause syndrome （PMS） and explore its possible action mechanism. Methods： All of 110 cases with PMS were randomized into group A [...Objective： To observe the clinical effect of electroacupuncture in treating perimenopause syndrome （PMS） and explore its possible action mechanism. Methods： All of 110 cases with PMS were randomized into group A [Guanyuan （CV 4） and Sanyinjiao （SP 6）] and group B [Neiguan （PC 6） and Zusanli （ST 36）], 55 cases in each. After 4-week treatments, the Kupperman Menopausal Index （KMI） was adopted to evaluate the therapeutic effect. Estradiol （E2）, follicle-stimulating hormone （FSH） and luteinizing hormone （LH） were assayed respectively before and after treatments. Results： The KMI decreased by 52.6% in group A, versus 47.4% in group B. The total effective rate was 93.6% in group A, versus 85.7% in group B, and the difference was not significant （P〈0.05）. The content of E2 both increased in the two groups after 4-week treatments （P〈0.05）; the contents of FSH and LH dropped but without statistical difference （P〈0.05）. Conclusion： Both of the two acupoints groups can significantly lower KMI, and effectively increase the contents of E2 in patients with PMS展开更多
Objective： To review the general study situation of perimenopausal syndrome treated with moxibustion, and to summarize the therapeutic rules of moxibustion for perimenopausal syndrome. Methods： The literature about ...Objective： To review the general study situation of perimenopausal syndrome treated with moxibustion, and to summarize the therapeutic rules of moxibustion for perimenopausal syndrome. Methods： The literature about clinical and experimental study on moxibustion treatment for perimenopausal syndrome since 1996 was sorted out and analyzed by computer search. Results and Conclusion： Twenty-nine articles were collected upon the criteria of recruitment. Mostly used methods were salt-partitioned and warming needle moxibustion, and the most frequently used meridians were Conception Vessel, Governor Vessel, Spleen Meridian, and Kidney Meridian. In acupoints, Shenque （CV 8）, Guanyuan （CV 4）, Mingmen （GV 4） and Yinbai （SP 1） were used in high freauecy.展开更多
In the present study, we aimed to retrospectively analyze the medication prescriptions of menopausal women diagnosed with menopausal syndrome in our hospital from 2015 to 2018, and compare the retention rate of estrog...In the present study, we aimed to retrospectively analyze the medication prescriptions of menopausal women diagnosed with menopausal syndrome in our hospital from 2015 to 2018, and compare the retention rate of estrogen and progesterone sequential therapy and hormone continuous therapy in menopausal women. The rational drug management system of Ningbo Women and Children’s hospital was used to screen the prescriptions of menopausal syndrome in 4 years. After the age, year included in the study, and prescription cost were adjusted, Kaplan-Meier regression analysis was performed to compare the prescription retention rates of the two drug regimens. The distribution of the two HRT regimens in the 4 years showed an increasing trend year by year, and the age groups of the two HRT regimens were mainly distributed between 41 and 60 years old, accounting for 97.1% and 87.06%, respectively. The cost distribution for the other two HRT regimens was approximately the same. Compared with the two HRT regimens, the drug retention rate of hormone continuous regimens was higher than that of hormone sequential regimens within 4 years. Kaplan-Meier regression analysis showed that the trend was significant(Tarone-Ware, Chi-square value = 3.857, P = 0.050). This study found that the median retention time of HRT therapy in menopausal women in our hospital was about half a year, which was significantly lower than that reported in previous studies of 1 year or longer. In addition, the present study found that compared with Femoston, the tibolone regimen significantly increased retention time in the treatment of menopausal syndrome.展开更多
Objective： To observe and evaluate the clinical effect of ear acupuncture in treating perimenopause syndrome. Methods： A multi-centered randomized controlled trial was conducted and the enrolled participants were di...Objective： To observe and evaluate the clinical effect of ear acupuncture in treating perimenopause syndrome. Methods： A multi-centered randomized controlled trial was conducted and the enrolled participants were divided into an ear acupuncture group and a control group. The ear acupuncture group was treated by electroacupuncture at auricular points, and the control one was prescribed for Geng Nian An （Menopause Helper） tablets. The therapeutic effects were evaluated after 10-day treatments. Results： For pre-menopausal patients, the total effective rate was 96.8% in the ear acupuncture group, versus 56.3% in the control. For post-menopausal patients, the total effective rate was 85.7% in the ear acupuncture group, versus 53.0% in the control. Conclusion： Both ear acupuncture and Geng Nian An （Menopause Helper） tablets were effective in ameliorating symptoms of perimenopause syndrome, with satisfactory compliance and safety. The clinical effect of ear acupuncture is better than that of Geng Nian An （Menopause Helper） tablets.展开更多
Objective： To explore the best opportunity for electroacupuncture therapy to treat perimenopause syndrome. Methods： The rats were duplicated as ovariectomized model and took the electroacupuncture therapy at 5 diffe...Objective： To explore the best opportunity for electroacupuncture therapy to treat perimenopause syndrome. Methods： The rats were duplicated as ovariectomized model and took the electroacupuncture therapy at 5 different periods. The heat-resistance ability, physical strength and sleeping ability of the rats at different intervention time were recorded. Results： For the rats with perimenopause syndrome at all periods, the electroacupuncture could promote the beat-resistance and the physical strength, shorten the sleep latency and prolong the sleeping time. The results of the rats in the 7 d pre-modeling group, 1 d post-modeling group and 8 d post-modeling group were the best, followed by the results of 15 d post-modeling group and 22 d post-modeling group. Conclusion： The prevention and early intervention of electroacupuncture on the rats with perimenopanse syndrome were satisfied and the effect declined with a later intervention time, indicating the importance of prevention and early intervention.展开更多
Objective： To observe the effect of combined acupuncture-moxibustion with psychotherapy in treating perimenopause syndrome. Methods： Eighty patients with perimenopause syndrome were randomized into two groups. Forty...Objective： To observe the effect of combined acupuncture-moxibustion with psychotherapy in treating perimenopause syndrome. Methods： Eighty patients with perimenopause syndrome were randomized into two groups. Forty-two patients in the treatment group were intervened by acupuncture-moxibustion and psychotherapy, and the other 38 in the control group were treated by acupuncture-moxibustion only. The treatment was given once a day, 15 times constitute a treatment course. The therapeutic effects were evaluated after 3 treatment courses. Results： The total effective rate and the effective rate of the emotional state were both 97.6% in the treatment group, versus 89.5% and 73.7% in the control. The comparison of the total effective rate and the effective rate of the emotional state between the two groups both showed significant difference （P〈0.05）. Conclusion： Acupuncture-moxibusiton has better effect in treating perimenopause syndrome when combined with psychotherapy.展开更多
文摘Objective： To observe the clinical effect of electroacupuncture in treating perimenopause syndrome （PMS） and explore its possible action mechanism. Methods： All of 110 cases with PMS were randomized into group A [Guanyuan （CV 4） and Sanyinjiao （SP 6）] and group B [Neiguan （PC 6） and Zusanli （ST 36）], 55 cases in each. After 4-week treatments, the Kupperman Menopausal Index （KMI） was adopted to evaluate the therapeutic effect. Estradiol （E2）, follicle-stimulating hormone （FSH） and luteinizing hormone （LH） were assayed respectively before and after treatments. Results： The KMI decreased by 52.6% in group A, versus 47.4% in group B. The total effective rate was 93.6% in group A, versus 85.7% in group B, and the difference was not significant （P〈0.05）. The content of E2 both increased in the two groups after 4-week treatments （P〈0.05）; the contents of FSH and LH dropped but without statistical difference （P〈0.05）. Conclusion： Both of the two acupoints groups can significantly lower KMI, and effectively increase the contents of E2 in patients with PMS
基金Shanghai Leading Academic Discipline P oject(S30304)Development Fund for Science and Technology Studies of Yueyang Hospital
文摘Objective： To review the general study situation of perimenopausal syndrome treated with moxibustion, and to summarize the therapeutic rules of moxibustion for perimenopausal syndrome. Methods： The literature about clinical and experimental study on moxibustion treatment for perimenopausal syndrome since 1996 was sorted out and analyzed by computer search. Results and Conclusion： Twenty-nine articles were collected upon the criteria of recruitment. Mostly used methods were salt-partitioned and warming needle moxibustion, and the most frequently used meridians were Conception Vessel, Governor Vessel, Spleen Meridian, and Kidney Meridian. In acupoints, Shenque （CV 8）, Guanyuan （CV 4）, Mingmen （GV 4） and Yinbai （SP 1） were used in high freauecy.
基金Ningbo Public Welfare Science and Technology Plan(Grant No.2019C50089)。
文摘In the present study, we aimed to retrospectively analyze the medication prescriptions of menopausal women diagnosed with menopausal syndrome in our hospital from 2015 to 2018, and compare the retention rate of estrogen and progesterone sequential therapy and hormone continuous therapy in menopausal women. The rational drug management system of Ningbo Women and Children’s hospital was used to screen the prescriptions of menopausal syndrome in 4 years. After the age, year included in the study, and prescription cost were adjusted, Kaplan-Meier regression analysis was performed to compare the prescription retention rates of the two drug regimens. The distribution of the two HRT regimens in the 4 years showed an increasing trend year by year, and the age groups of the two HRT regimens were mainly distributed between 41 and 60 years old, accounting for 97.1% and 87.06%, respectively. The cost distribution for the other two HRT regimens was approximately the same. Compared with the two HRT regimens, the drug retention rate of hormone continuous regimens was higher than that of hormone sequential regimens within 4 years. Kaplan-Meier regression analysis showed that the trend was significant(Tarone-Ware, Chi-square value = 3.857, P = 0.050). This study found that the median retention time of HRT therapy in menopausal women in our hospital was about half a year, which was significantly lower than that reported in previous studies of 1 year or longer. In addition, the present study found that compared with Femoston, the tibolone regimen significantly increased retention time in the treatment of menopausal syndrome.
基金Project of Science and Technology Development of Hangzhou (20070433Q26)
文摘Objective： To observe and evaluate the clinical effect of ear acupuncture in treating perimenopause syndrome. Methods： A multi-centered randomized controlled trial was conducted and the enrolled participants were divided into an ear acupuncture group and a control group. The ear acupuncture group was treated by electroacupuncture at auricular points, and the control one was prescribed for Geng Nian An （Menopause Helper） tablets. The therapeutic effects were evaluated after 10-day treatments. Results： For pre-menopausal patients, the total effective rate was 96.8% in the ear acupuncture group, versus 56.3% in the control. For post-menopausal patients, the total effective rate was 85.7% in the ear acupuncture group, versus 53.0% in the control. Conclusion： Both ear acupuncture and Geng Nian An （Menopause Helper） tablets were effective in ameliorating symptoms of perimenopause syndrome, with satisfactory compliance and safety. The clinical effect of ear acupuncture is better than that of Geng Nian An （Menopause Helper） tablets.
基金Key Project of Hangzhou Municipal Health Bureau(20072004)
文摘Objective： To explore the best opportunity for electroacupuncture therapy to treat perimenopause syndrome. Methods： The rats were duplicated as ovariectomized model and took the electroacupuncture therapy at 5 different periods. The heat-resistance ability, physical strength and sleeping ability of the rats at different intervention time were recorded. Results： For the rats with perimenopause syndrome at all periods, the electroacupuncture could promote the beat-resistance and the physical strength, shorten the sleep latency and prolong the sleeping time. The results of the rats in the 7 d pre-modeling group, 1 d post-modeling group and 8 d post-modeling group were the best, followed by the results of 15 d post-modeling group and 22 d post-modeling group. Conclusion： The prevention and early intervention of electroacupuncture on the rats with perimenopanse syndrome were satisfied and the effect declined with a later intervention time, indicating the importance of prevention and early intervention.
文摘Objective： To observe the effect of combined acupuncture-moxibustion with psychotherapy in treating perimenopause syndrome. Methods： Eighty patients with perimenopause syndrome were randomized into two groups. Forty-two patients in the treatment group were intervened by acupuncture-moxibustion and psychotherapy, and the other 38 in the control group were treated by acupuncture-moxibustion only. The treatment was given once a day, 15 times constitute a treatment course. The therapeutic effects were evaluated after 3 treatment courses. Results： The total effective rate and the effective rate of the emotional state were both 97.6% in the treatment group, versus 89.5% and 73.7% in the control. The comparison of the total effective rate and the effective rate of the emotional state between the two groups both showed significant difference （P〈0.05）. Conclusion： Acupuncture-moxibusiton has better effect in treating perimenopause syndrome when combined with psychotherapy.
