经激光汽化术治疗高危前列腺增生症病人的围手术期精细化护理

对高危前列腺增生患者采取精细化护理,观察干预效果。方法:对2020年3月-2021年4月的患者进行精细化护理。结果:通过对患者进行手术后,缩短了患者的手术时间、膀胱冲洗时间、保留尿管时长、及患者术后住院时长, 并且在患者出院后对患者进行随访,发现患者的排尿功能恢复,术后并发症的发生减少,增加了满意度。结论:对患者进行精细化护理能够加快患者术后恢复速度,促进患者排尿,并且并未发生并发症,增加了患者对医护人员护理的满意度,值得应用于临床之中。

高功率激光器窗口热变形分析的有限元方法

建立了窗口热变形的非稳态数学模型，采用有限元法计算了普通石英窗口和中心冷却窗口在激光照射下的温度场分布和热变形，在净吸收功率５０Ｗ的相同条件下，普通石英窗口最大热变形为２．４μｍ，中央冷却窗口为１．２μｍ，计算结果与实验数据相符。

经皮激光间盘减压术落户我国

吉林大学第二医院骨科杨有庚等人在国内率先使用"经皮激光间盘减压术"

Optical-neural Stimulation in Non-human Primates:Modulating Brain Function and Behavior

Optical-neural stimulation,which encompasses cutting-edge techniques such as optogenetics and infrared neurostimulation,employs distinct mechanisms to modulate brain function and behavior.These advanced neuromodulation techniques offer accurate manipulation of targeted areas,even selectively modulating specific neurons,in the brain.This makes it possible to investigate the cause-and-effect connections between neural activity and behavior,allowing for a better comprehension of the intricate brain dynamics towards complex environments.Non-human primates serve as an essential animal model for investigating these complex functions in brain research,bridging the gap between the basic research and clinical applications.One of the earliest optical studies utilizing optogenetic neuromodulation in monkeys was conducted in 2009.Since then,the optical-neural stimulations have been effectively applied in non-human primates.This review summarises recent research that employed optogenetics or infrared neurostimulation techniques to regulate brain function and behavior in non-human primates.The current state of optical-neural stimulations discussed here demonstrates their efficacy in advancing the understanding of brain systems.Nevertheless,there are still challenges that need to be addressed before they can fully achieve their potential.

Effects of spinal cord stimulation on cerebrovascular flow: role of sym-pathetic and parasympathetic innervations

Objective Cervical spinal cord stimulation （SCS） has been found to augment cerebral blood flow （CBF） in a number of animal models. However, the effective use of SCS is hampered by a lack of understanding of its mechanism（s） of action. In this paper, we focus on the sympathetic and parasympathetic effects of SCS on CBF. Method SpragueDawley rats were selected for the experimental series. The animals were divided into 5 groups to underwent SCS and laser Doppler flowmeter （LDF） recordings. Control group, the animal underwent SCS and LDF recordings without any surgery of the nerve fibers and ganglia. V 1 group, the animal underwent bilateral resection of the nasociliary and post-ganglionic parasympathetic nerve fibbers. SCG group, the animal underwent bilateral resection of supper cervical ganglion. V 1 ＋ SCG group, the animal underwent both surgeries as V1- and SCG-group animals did. Sham group, the animal underwent the carotid manipulation with blunt-tipped forceps as well as the dissection of nasociliary and post-ganglionic parasympathetic nerve fibers around the ethmoidal foramen, but without cutting any nerves. Results During the SCS, the LDF was no statistical difference between the V 1 or SCG group and the control group. Yet, the effects of SCS on CBF are completely abolished in V1＋ SCG group. Conclusions Surgical interruption of both the parasympathetic and sympathetic pathways has the contradict effect on SCS-induced CBF augmentation.

Supra—thermal Electron Generation at Moderate Laser Intensity

The effects of re-scattering on the supra-thermal electron (STE) produced in moderate laser fields are analytically considered (laser intensity is up to ) with a simple model. The electron kinetic energy distribution given by the model is consistent to that given by the particle-in-cell simulation. Based on this fact, it is shown that the scattering of electron in intense laser by the ion in plasma plays an important role in the generation of STE in a moderate laser field.

Application of 2-D Position Sensitive Detector in Spatial Straightness Measurement of Guide Rails

A laser collimating system based on 2-D position sensitive detector (PSD) is presented in this paper. The working principle of PSD is depicted in detail. A calibration device was developed to check the nonlinearity errors of PSD and a multilayer feedforward neural network based on error back-propagation algorithm was used to compensate errors. With the aid of computer-based data acquisition system, an automatic dynamic measuring process was realized. A series of experiments, including comparison tests with laser interferometer, were done to evaluate the performance of the measuring system. The experimental results show that the spatial straightness errors of guide rails can be measured with high accuracy. The maximum differences between the device and laser interferometer are 0.027 mm in Y direction, and 0.053 mm in X direction in the measuring distance of 6 m.

Automated Building Block Extraction and Building Density Classification Using Aerial Imagery and LiDAR Data

This paper examines the utility of high-resolution airborne RGB orthophotos and LiDAR data for mapping residential land uses within the spatial limits of suburb of Athens, Greece. Modem remote sensors deliver ample information from the AOI （area of interest） for the estimation of 2D indicators or with the inclusion of elevation data 3D indicators for the classification of urban land. In this research, two of these indicators, BCR （building coverage ratio） and FAR （floor area ratio） are automatically evaluated. In the pre-processing step, the low resolution elevation data are fused with the high resolution optical data through a mean-shift based discontinuity preserving smoothing algorithm. The outcome is an nDSM （normalized digital surface model） comprised of upsampled elevation data with considerable improvement regarding region filling and ＂straightness＂ of elevation discontinuities. Following this step, a MFNN （multilayer feedforward neural network） is used to classify all pixels of the AOI into building or non-building categories. The information derived from the BCR and FAR building indicators, adapted to landscape characteristics of the test area is used to propose two new indices and an automatic post-classification based on the density of buildings.

CLINICAL STUDY OF LASERNEEDLE ACUPUNCTURE

We are reporting over 500 acupuncture cases, a wide range of illnesses ranging from orthopedic, internal, neurological and psychological diseases, all of which were treated with a newly developed and therefore available Laserneedle system. This system was highly successful in treatment of a variety of illnesses including HWS, BWS and LWS Syndromes, gonarthritis, coxarthritis, rhizarthrosis, periarthritis of the shoulder, epicondylitis humeri radialis, tendinitis, fibromyalgia and PCP, Morbus Bechterew, paralysis after stroke, migraine and other headache syndrome, tinnitus, trigeminal neuralgia, gastropathy, bronchial asthma, AVK, mental depression and other psychovegatative burnout syndrome by using both body acupoints and otopoints. Treatment was made by simultaneously using 8 Laserneedles which were not pricked into, but stuck onto the skin. The Laserneedles emit red and infrared Laserrays with a high energy output, so that perceptible, vegetative stimulation can be detected at the acupunctrured sites. We found out, that especially in the therapy resistant, long standing cases and cases with chronic back and spine problems, considerable improvements in easing pain and increasing mobility could be made. Recognizable success was made by using Laserneedles in cases suffering from psychological illnesses, especially psychosomatic related Burnout syndrome and cases of exhaustion. Usually after 2～3 treatments, efficient success was made, without any side effects what so ever.

Full-Dimensional Potential Energy Surfaces of Ground(X^(2)A′)and Excited(A^(2)A″)Electronic States of HCO and Absorption Spectrum

In this work,high-fidelity full-dimensional potential energy surfaces(PESs)of the ground(X^(2)A′)and first doublet excited(A^(2)A″)electronic states of HCO were constructed using neural network method.In total,4624 high-level ab initio points have been used which were calculated at Davidson corrected internally contracted MRCI-F12 level of theory with a quite large basis set(ACV5Z)without any scaling scheme.Compared with the results obtained from the scaled PESs of Ndenguéet al.,the absorption spectrum based on our PESs has slightly larger intensity,and the peak positions are shifted to smaller energy for dozens of wavenumbers.It is indicated that the scaling of potential energy may make some unpredictable difference on the dynamical results.However,the resonance energies based on those scaled PESs are slightly closer to the current available experimental values than ours.Nevertheless,the unscaled high-level PESs developed in this work might provide a platform for further experimental and theoretical photodissociation and collisional dynamic studies for HCO system.

Microfabrication,surface modification,and laser guidance techniques to create a neuron biochip

In this report we illustrate our application of soft lithography-based microfabrication,surface modification,and our unique laser cell-patterning system toward the creation of neuron biochips. We deposited individual forebrain neurons from Day 7 embryonic chicks into two rows of eight in a silicon microstructure aligned over a microelectrode array (MEA). The polydimethylsiloxane (PDMS) membrane with microstructures to confine cells and guide network connectivity was aligned to the electrodes of a MEA. Both the MEA and the PDMS membrane were treated with O2 plasma,Poly-L-Lysine,and Laminin to aid in cell attachment and survival. The primary advantage of our process is that it is quicker and simpler than previous cell-placement methods and may make highly defined neuronal network biochips more practical.

Error assessment of laser cutting predictions by semi-supervised learning

Experimentation data of perspex glass sheet cutting, using CO2 laser, with missing values were modelled with semi-supervised artificial neural networks. Factorial design of experiment was selected for the verification of orthogonal array based model prediction. It shows improvement in modelling of edge quality and kerf width by applying semi-supervised learning algorithm, based on novel error assessment on simulations. The results are expected to depict better prediction on average by utilizing the systematic randomized techniques to initialize the neural network weights and increase the number of initialization. Missing values handling is difficult with statistical tools and supervised learning techniques; on the other hand, semi-supervised learning generates better results with the smallest datasets even with missing values.

Effects of SKF-96365, a TRPC inhibitor, on melittin-induced inward current and intracellular Ca^2+ rise in primary sensory cells

Objective Melittin （MEL） is a major component of bee venom and can produce both persistent spontaneous nociception and pain hypersensitivity when injected subcutaneously in the periphery. The present study aimed to examine the roles of transient receptor potential canonical （TRPC） channels in mediation of MEL-indueed activation of primary nociceptive cells. Methods Whole-cell patch-clamp and laser scanning confocal calcium detection were used to evalu- ate the effects of SKF-96365, a TRPC inhibitor, applied on the acutely isolated dorsal root ganglion （DRG） cells of rat, on MEL-induced increase in intracellular calcium concentration （[Ca2＋]i） and inward current. Results Under voltage- clamp mode, 43.9% （40/91） DRG cells were evoked to give rise to the inward current by 2 pmol/L MEL, which could be significantly suppressed by 3 doses of SKF-96365 （1, 5 and 10μmol/L） in a dose-dependent manner. Of the other 210 cells, 67.6% responded to MEL with an intracellular Ca2＋ rise, as revealed by confocal calcium imaging. Of these MEL- sensitive cells, 46.5% （66/142） were suppressed by the highest dose of SKF-96365. Conclusion MEL-induced activation of small to medium-sized DRG cells can be suppressed by SKF-96365, suggesting the involvement of TRPC channels in the mediation of MEL-induced activation of primary nociceptive cells.

Modulating nitric oxide levels in dorsal root ganglion neurons of rat with low-level laser therapy

Nitric oxide(NO)and nitric oxide synthase(NOS)have an important role in pain signaling transmission in animal models.Low-level laser therapy(LLLT)is known to have an analgesic effect,but the mechanism is unclear.The aim of the study is to investigate the influence of LLLT on NO release and NOS synthesis in dorsal root ganglion(DRG)neurons,in order to find whether LLLI can ameliorate pain through modulating NO production at the cellular level.The results show that in stress conditions,the laser irradiation at 658 nm can modulate NO production in DRG neurons with soma diameter of about 20μm in a short time after illumination,and affect NOS synthesis in a dose-dependent manner.It is demonstrated that LLLT might treat pain by altering NO release directly and indirectly in DRG neurons.

He-Ne laser acupuncture for 30 cases of unilateral nervous tinnitus

Objective： To observe the clinical effects of the unilateral nervous tinnitus treated by He-Ne laser acupuncture.Methods： A total of 30 patients of unilateral nervous tinnitus were treated with He-Ne laser acupuncture.The disposable filiform needles of 0.40 mm × 25 mm were used. Ermén（耳门 TE 21）, Tīnggōng（听宫 SI 19）,Tinghui（听会 GB 2）, Yìfēng（翳风 TE 17）,Shuàigǔ（率谷 GB 8） and Zhōngzhǔ（中渚 TE 3） were adopted on the affected side. The input and output ends of the fiber-optic catheter of the laser instrument were connected at a pair of acupoints（TE 21 connect to SI 19, GB 2 connect to TE 17, GB 8 connect to TE 3）.Each pair of acupoints was stimulated with He-Ne laser irradiation for 10 min, 8-10 mW in the output power and 6328 A in the wavelength. The needles were retained for 30 min totally. The treatment was given once a day, 5 times a week, continuously for 2 weeks.Results： Of 30 cases, 19 cases were cured clinically, accounting for 63.3%（19/30）; 7 cases effective remarkably, accounting for 23.3%（7/30） and 4 cases failed, accounting for 13.3%（4/30）.Conclusion： He-Ne laser acupuncture achieves the satisfactory effects on treating nervous tinnitus and it is easily accepted by the patients. Hence, this therapy deserves to be promoted in clinical application.