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冠心病老年患者经皮冠动脉介入治疗术后支架内再狭窄发生率及危险因素研究 被引量:5
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作者 张小芳 何文君 《中国医院统计》 2017年第1期1-4,共4页
目的探讨冠心病老年患者经皮冠动脉介入治疗术后支架内再狭窄发生率及危险因素,为经皮冠动脉介入治疗术后支架内再狭窄的防治提供参考。方法收集经皮冠动脉介入治疗术后的老年冠心病患者临床资料,选择完成12个月随访并复查动脉造影的47... 目的探讨冠心病老年患者经皮冠动脉介入治疗术后支架内再狭窄发生率及危险因素,为经皮冠动脉介入治疗术后支架内再狭窄的防治提供参考。方法收集经皮冠动脉介入治疗术后的老年冠心病患者临床资料,选择完成12个月随访并复查动脉造影的475例病例资料,统计支架内再狭窄发生率并分层比较,根据是否发生支架内再狭窄分组,比较组间相关因素的差异,并筛选自变量纳入logistic回归进行多因素分析。结果随访475例经皮冠动脉介入治疗术后患者,共植入611支支架,51例(10.67%)患者71支(11.62%)发生支架内再狭窄,男性支架内再狭窄发生率(12.24%)高于女性(6.82%),差异有统计学意义(P<0.05);单因素分析显示,是否合并T2DM、hsCRP、支架直径、支架长度、支架数量组间差异有统计学意义(P<0.05);多因素logistic回归分析显示,是否合并T2DM(OR=2.467,95%CI为1.455~5.767)、hsCRP(OR=6.515,95%CI为2.455~18.767)、支架直径(OR=4.120,95%CI为1.574~14.644)、支架长度(OR=1.996,95%CI为1.387~3.895)、支架数量(OR=3.425,95%CI为1.812~6.774)是支架内再狭窄的独立影响因素。结论冠心病老年患者经皮冠动脉介入治疗术后支架内再狭窄发生率仍然较高,合并T2DM、术后血浆hsCRP水平高、支架直径短、长度长、数量多可能是支架内再狭窄的危险因素。 展开更多
关键词 冠心病 经皮冠动脉介入治疗 支架内再狭窄 危险因素
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急性心肌梗死介入治疗中并发室颤的抢救 被引量:5
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作者 张贵生 潘桂华 +2 位作者 刘彩萍 张文玲 李隆贵 《实用诊断与治疗杂志》 2008年第4期317-318,共2页
目的:探讨经皮冠状动脉介入治疗急性心肌梗死过程中心室颤动的抢救。方法:968例急性心肌梗死患者,在急诊经皮腔冠状动脉介入治疗过程中发生心室颤动15例,立即给予有效的电击除颤、心外按压、心电监护,保持呼吸道通畅,维持正常血压及水... 目的:探讨经皮冠状动脉介入治疗急性心肌梗死过程中心室颤动的抢救。方法:968例急性心肌梗死患者,在急诊经皮腔冠状动脉介入治疗过程中发生心室颤动15例,立即给予有效的电击除颤、心外按压、心电监护,保持呼吸道通畅,维持正常血压及水电解质平衡等一系列抢救措施。结果:15例患者经及时积极抢救均获成功。结论:急诊冠脉介入治疗急性心肌梗死过程中一旦发生心室颤动,需采取及时、积极及正确的抢救措施,降低患者病死率。 展开更多
关键词 急性心肌梗死 经皮冠动脉介入治疗 心室颤动 抢救
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为接受PCI的急性冠状动脉综合征患者使用替格瑞洛与氯吡格雷进行治疗的效果对比 被引量:1
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作者 冯倩 赵东坡 孙小燕 《当代医药论丛》 2019年第1期115-116,共2页
目的:比较为接受PCI(经皮冠状动脉介入治疗)的急性冠状动脉综合征患者使用替格瑞洛与氯吡格雷进行治疗的效果。方法:选取张家口市第一医院收治的110例急性冠状动脉综合征患者作为研究对象。将这110例患者平均分为对照组和观察组。为对... 目的:比较为接受PCI(经皮冠状动脉介入治疗)的急性冠状动脉综合征患者使用替格瑞洛与氯吡格雷进行治疗的效果。方法:选取张家口市第一医院收治的110例急性冠状动脉综合征患者作为研究对象。将这110例患者平均分为对照组和观察组。为对照组患者使用氯吡格雷进行治疗。为观察组患者使用替格瑞洛进行治疗。然后,比较两组患者血小板最大聚集率(MPAR)、血浆内皮素-1(ET-1)的水平、血浆超敏C-反应蛋白(hs-CRP)的水平、血浆一氧化氮(NO)的水平、血小板P2Y12反应单位(PRU)。结果:接受治疗后,观察组患者MPAR、PRU、血浆hs-CRP的水平及血浆ET-1的水平均低于对照组患者,其NO的水平高于对照组患者(P <0.05)。结论:与采用氯吡格雷进行治疗相比,为接受经皮冠状动脉介入治疗的急性冠状动脉综合征患者使用替格瑞洛进行治疗的效果更好。 展开更多
关键词 氯吡格雷 替格瑞洛 急性冠状综合征 经皮冠动脉介入治疗
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CYP2C19基因多态性及氯吡格雷抵抗对经皮冠状动脉介入术预后影响的回顾性研究 被引量:2
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作者 李赛 栗印军 +7 位作者 姜镇 邢宇 韦伟 包博 李欣 郭万超 吴洋 步佳琳 《中国实用内科杂志》 CSCD 北大核心 2023年第5期401-406,共6页
目的评价CYP2C19基因多态性及经皮冠状动脉介入治疗(PCI)术后患者氯吡格雷抵抗对预后的影响,为以CYP2C19基因多态性进行抗血小板药物选择提供理论基础。方法研究对象为2015年12月至2018年12月在沈阳市第四人民医院诊断为急性冠脉综合征(... 目的评价CYP2C19基因多态性及经皮冠状动脉介入治疗(PCI)术后患者氯吡格雷抵抗对预后的影响,为以CYP2C19基因多态性进行抗血小板药物选择提供理论基础。方法研究对象为2015年12月至2018年12月在沈阳市第四人民医院诊断为急性冠脉综合征(ACS)、行PCI治疗并检测CYP2C19基因型的536例患者,进行回顾性队列研究。观察CYP2C19基因多态性分布及其与氯吡格雷抵抗和主要不良心脑血管事件(MACCE)的关系,分析MACCE的危险因素,绘制5年生存曲线。结果(1)慢、中间及快代谢型患者5年生存率无显著性差异;(2)氯吡格雷抵抗与非抵抗组相比,PCI术后患者5年生存率无显著性差异;(3)在三组不同代谢类型患者中分别对氯吡格雷抵抗与非抵抗组进行5年生存率比较,PCI术后远期生存率差异无统计学意义;(4)高龄(>75岁)、性别(男性)、高体质指数(BMI≥24)、糖尿病、吸烟、支架数(≥3枚)、多支血管病变(≥2支)与氯吡格雷抵抗为MACCE的危险因素,而CYP2C19基因多态性不是MACCE的危险因素,高BMI及氯吡格雷抵抗是MACCE的独立危险因素。结论CYP2C19基因多态性及氯吡格雷抵抗对患者远期生存无显著影响,高BMI患者行CYP2C19基因检测对指导抗血栓治疗更有意义。 展开更多
关键词 CYP2C19基因多态性 氯吡格雷抵抗 经皮冠动脉介入治疗 预后
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Family care and subjective well-being of coronary heart disease patients after percutaneous coronary intervention:Mediating effects of coping strategies 被引量:5
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作者 Li-Xia Liang Yu Liu +5 位作者 Ya-Jie Shi Tong-Tong Jiang Hong-Ru Zhang Bing-Han Liu Peng-Zhu Xu Tie-Ying Shi 《International Journal of Nursing Sciences》 CSCD 2022年第1期79-85,I0005,共8页
Objectives To analyze the correlations between family care,coping strategies and the subject well-being(SWB)of patients with coronary heart disease(CHD)after percutaneous coronary intervention(PCI).Methods From Novemb... Objectives To analyze the correlations between family care,coping strategies and the subject well-being(SWB)of patients with coronary heart disease(CHD)after percutaneous coronary intervention(PCI).Methods From November 2019 to October 2020,264 CHD patients who had undergone PCI were enrolled in this questionnaire survey.The research tools applied included General Information Questionnaire,the Adaptation,Partnership,Growth,Affection and Resolve,Medical Coping Modes Questionnaire,and the General Well-being Schedule.SPSS 24.0 and Amos 23.0 software packages were used for statistical analysis.Results The mean scores for family care,confrontation,avoidance,acceptance-resignation and SWB,were 7.59±2.24,20.03±3.78,16.49±2.70,10.42±2.01,and 73.31±11.63,respectively.Subgroup analysis showed that the path coefficient between family care and subjective well-being was higher in males than females.Family care was directly related to coping strategies.The coping strategies were directly related to SWB,while family care showed an indirect association with SWB via coping strategies.Conclusions Family care can improve CHD patients’SWB post-PCI,and coping strategies are important for the link between family care and SWB.Also,men received more family care than women.Based on a patient's characteristics,healthcare providers can promote patients’positive coping strategies,increase their perceived family care,and improve the patient's SWB. 展开更多
关键词 Coping strategies Coronary disease Family care Percutaneous coronary intervention Subjective well-being
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Effects of multidisciplinary exercise management on patients after percutaneous coronary intervention:A randomized controlled study 被引量:4
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作者 Ya-Jie Shi Yu Liu +2 位作者 Tong-Tong Jiang Hong-Ru Zhang Tie-Ying Shi 《International Journal of Nursing Sciences》 CSCD 2022年第3期286-294,共9页
Objectives To explore the effectiveness of the mobile app-based multidisciplinary exercise management on patients who receive percutaneous coronary intervention(PCI).Methods From January to October 2020,54 patients af... Objectives To explore the effectiveness of the mobile app-based multidisciplinary exercise management on patients who receive percutaneous coronary intervention(PCI).Methods From January to October 2020,54 patients after PCI were randomly assigned to the intervention group(n=27)and the control group(n=27).The intervention group received the mobile app-based multidisciplinary exercise management,whereas the control group received routine care.The patients after PCI began to take intervention one month after the operation,and the intervention lasted for two months.Before and after the intervention,6-Minute Walking Distance was used to evaluate the patient’s exercise tolerance,and the patient’s exercise compliance was evaluated according to the patient’s exercise status recorded by the mobile app.The cognitive questionnaire on knowledge about PCI treatment for Coronary Heart Disease,the Self-efficacy for Chronic Disease Scale and the Perceived Social Support Scale were used to evaluate patients’disease-related cognition,self-efficacy and perception of social support.This study was registered on Clinical Trials.gov with registration number ChiCTR2000028930.Results Totally 51 patients after PCI who completed this study(25 patients in the intervention group and 26 patients in the control group)were included in the analysis.After 2 months of intervention,the exercise compliance of patients in the intervention group was better than that in the control group.And 6-Minute Walking Distance(469.36±57.48 vs.432.81±67.09),and the scores of knowledge of PCI treatment for coronary heart disease(52.64±9.82 vs.42.42±8.54),Self-efficacy for Chronic Disease Scale(42.40±8.04 vs.36.88±7.73)and Perceived Social Support Scale(74.04±5.73 vs.66.69±6.86)in the intervention group were higher than those in the control group with statistical significance(P<0.05).Conclusions The multidisciplinary exercise management based on the mobile app can effectively improve exercise tolerance,exercise compliance,disease-related cognition,self-efficacy,and perception of social support during exercise training for patients after PCI. 展开更多
关键词 Coronary disease EXERCISE Exercise tolerance Mobile applications Percutaneous coronary intervention Self efficacy Social support
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Retrospective analysis of exercise capacity in patients with coronary artery disease after percutaneous coronary intervention or coronary artery bypass graft 被引量:5
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作者 Ying Li Xue Feng +1 位作者 Biyun Chen Huaping Liu 《International Journal of Nursing Sciences》 CSCD 2021年第3期257-263,I0001,共8页
Objectives:To describe the current state of exercise capacity as well as to identify its predictors in patients with coronary artery disease (CAD) following percutaneous coronary intervention (PCI) or coronary artery ... Objectives:To describe the current state of exercise capacity as well as to identify its predictors in patients with coronary artery disease (CAD) following percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) in the mainland of China.Methods:A retrospective study design was employed.We evaluated 230 CAD patients following PCI or CABG in a cardiac rehabilitation center from January 2019 to October 2019.The patients were referred to undergo incremental cardiopulmonary exercise testing with a cycle ergometer.The Zung Self-Rating Anxiety Scale and the Zung Self-Rating Depression Scale were used to evaluate patients' mental health.Statistical analysis was performed using the chi-square test,Fisher's exact test,t-test,Mann-Whitney U test,and binary logistic regression.Results:Among the 230 patients,223 patients demonstrated reduced exercise capacity.Resutlts of the logistic regression analysis showed that anxiety (OR =1.13,95% CI 1.01-1.32,P =0.029) was an independent risk factor for reduced exercise capacity in patients following the PCI or CABG.Conclusions:Exercise capacity of Chinese CAD patients after PCI or CABG was relatively poor.Alleviating symptoms of anxiety and making exercise prescriptions according to the results of the cardiopulmonary exercise test should be considered during the intervention to improve CAD patients' exercise capacity. 展开更多
关键词 ANXIETY Coronary artery bypass Coronary artery disease Cardiac rehabilitation DEPRESSION Exercise test Exercise tolerance Percutaneous coronary intervention
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PCI治疗对急性冠脉综合征患者血浆可溶性CD40配体及基质金属蛋白酶-9的影响 被引量:1
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作者 王蕊 张鹏祥 +4 位作者 李飞星 王晓元 郝翠君 李会贤 李方江 《基因组学与应用生物学》 CAS CSCD 北大核心 2019年第10期4837-4841,共5页
为了分析经皮冠动脉介入治疗(percutaneous coronary intervention,PCI)对不同年龄组急性冠脉综合征(acute coronary syndrome,ACS)患者血清重组可溶性CD40配体(recombinant soluble CD40 ligand,sCD40L)和金属蛋白酶-9(matrix metallop... 为了分析经皮冠动脉介入治疗(percutaneous coronary intervention,PCI)对不同年龄组急性冠脉综合征(acute coronary syndrome,ACS)患者血清重组可溶性CD40配体(recombinant soluble CD40 ligand,sCD40L)和金属蛋白酶-9(matrix metalloproteinase-9,MMP-9)水平的影响。本研究随机选取40例健康志愿者、就诊的40例急性心肌梗死(acute myocardial infarction,AMI)和40例不稳定心绞痛(unstable angina pectoris,UAP),按年龄≤60岁为一组,>60岁为一组,每组20例。分别在PCI治疗前1 d、治疗后1 d和7 d测定并统计各组间血清sCD40L和MMP-9水平变化。ACS患者血清sCD40L和MMP-9水平均明显高于对照组(p<0.05);>60岁的ACS患者血清sCD40L水平略高于≤60岁患者,但是无显著性差异(p>0.05);PCI治疗1 d后可增加ACS患者的血清sCD40L和MMP-9水平(p<0.01),7 d后则逐渐下降。ACS患者的血清sCD40L和MMP-9水平变化与年龄无明显关系;PCI治疗可能加重了冠状动脉内早期炎症,致使血清sCD40L和MMP-9水平在短期内增加,后期则逐渐恢复正常。 展开更多
关键词 急性冠脉综合征 经皮冠动脉介入治疗 重组人可溶性CD40配体 金属蛋白酶-9
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Coronary arteriography under acupuncture anesthesia:a case report 被引量:1
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作者 李璟 樊民 +4 位作者 周嘉 朱岩峰 顾侃 李琪 洪珏 《Journal of Acupuncture and Tuina Science》 CSCD 2018年第5期319-322,共4页
Acupuncture anesthesia is a technique by partially or completely replacing anesthetics with acupuncture in surgery based on the traditional acupuncture analgesia mechanism.It emerged in the 1950s,went viral in the 197... Acupuncture anesthesia is a technique by partially or completely replacing anesthetics with acupuncture in surgery based on the traditional acupuncture analgesia mechanism.It emerged in the 1950s,went viral in the 1970s and then gradually fell into decline.In the recent years,this technique has regained attention and further research.Acupuncture anesthesia can be classified as either pure acupuncture anesthesia or acupuncture-medication combined anesthesia.To expand the application of this technique,a patient with non-ST elevation acute coronary syndrome in urgent need of percutaneous coronary intervention (PCI) received pure acupuncture anesthesia because of an allergy to lidocaine,and the operation went successfully.This is the first time that pure acupuncture anesthesia and coronary arteriography were combined,which is of great significance in further study and development of acupuncture anesthesia. 展开更多
关键词 Acupuncture Therapy Acupuncture Analgesia Acute Coronary Syndrome Non-ST Elevated Myocardial Infarction Percutaneous Coronary Intervention Point Neiguan (PC 6) Point Lieque (LU 7)
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