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微创介入技术治疗症状性多囊肝的临床应用及进展
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作者 梁逸宁 杜贞华 +1 位作者 王志龙 左太阳 《介入放射学杂志》 CSCD 北大核心 2024年第2期208-212,共5页
多囊性肝病(polycystic liver disease,PLD)是一种罕见的遗传性疾病,多数患者无临床症状,少数伴有严重并发症的症状性多囊肝需要治疗。肝移植是症状性多囊肝病患者唯一的根治方法,但由于供体缺乏、手术费用昂贵,且风险大,多数患者无法... 多囊性肝病(polycystic liver disease,PLD)是一种罕见的遗传性疾病,多数患者无临床症状,少数伴有严重并发症的症状性多囊肝需要治疗。肝移植是症状性多囊肝病患者唯一的根治方法,但由于供体缺乏、手术费用昂贵,且风险大,多数患者无法进行肝移植。近年来以经皮囊肿硬化术及经动脉栓塞术为代表的微创介入技术以其创伤小、恢复快、可重复、安全性高、并发症较少等诸多优势,已成功应用于治疗症状性多囊肝,并取得了医患双方的认可。因此微创介入技术将是未来症状性多囊肝治疗的发展方向,可以改善局部症状、提高患者的生活质量。本文旨在对经皮囊肿硬化术及经动脉栓塞术治疗症状性多囊肝的原理机制、引导方式、适应证及禁忌证,在治疗多囊肝临床应用中存在的优势与不足以及相关并发症进行综述。 展开更多
关键词 症状性多囊肝 经皮囊肿硬化术 经动脉栓塞
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Results of percutaneous sclerotherapy and surgical treatment in patients with symptomatic simple liver cysts and polycystic liver disease 被引量:16
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作者 Deha Erdogan Otto M van Delden +4 位作者 Erik AJ Rauws Olivier RC Busch Johan S Lameris Dirk J Gouma Thomas M van Gulik 《World Journal of Gastroenterology》 SCIE CAS CSCD 2007年第22期3095-3100,共6页
AIM: To evaluate the results of the treatment of simple liver cysts (solitary and multiple) and polycystic liver disease (PLD) using percutaneous sclerotherapy and/or surgical procedures in a single tertiary referral ... AIM: To evaluate the results of the treatment of simple liver cysts (solitary and multiple) and polycystic liver disease (PLD) using percutaneous sclerotherapy and/or surgical procedures in a single tertiary referral centre. METHODS: Retrospective analysis of 54 patients referred for evaluation and possible treatment of simple liver cysts (solitary and multiple) and PLD, from January 1997 to July 2006. RESULTS: Simple liver cysts were treated in 41 pts (76/) with a mean size of 12.6 cm. The most common reason for referral was abdominal pain or discomfort (85/). Percutaneous sclerotherapy was performed as initial treatment in 30 pts, showing cyst recurrence in 6 pts (20/). Surgical treatment was initially performed in 11 pts with cyst recurrence in 3 pts (27/). PLD was treated in 13 pts (24/) with a mean size of the dominant cyst of 13 cm. Percutaneous sclerotherapy for PLD was performed in 9 pts with recurrence in 7 pts (77.8/). Surgical treatment for PLD was undertaken in 4 pts (30.8/) with recurrence in all. Eventually, 2 pts with PLD in the presence of polycystic kidney disease underwent liver-and kidney transplantation because of deterioration of liver and kidney function. CONCLUSION: The majority of patients with simple liver cysts and PLD are referred for progressive abdominal pain. As initial treatment, percutaneous sclerotherapy is appropriate. Surgical deroofing is indicated in caseof cyst recurrence after percutaneous sclerotherapy. However, the results of percutaneous sclerotherapy and surgical treatment for PLD are disappointing. Partial liver resection is indicated when there is suspicion of a pre-malignant lesion. 展开更多
关键词 Simple liver cyst Polycystic liver disease Percutaneous sclerotherapy Deroofing COMPLICATIONS
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