目的:探究经皮神经穴位电刺激对慢性阻塞性肺疾病(Chronic obstructive pulmonary disease,COPD)稳定期患者临床疗效、肺功能及急性加重风险的影响。方法:选取2021年12月~2022年12月来我院就诊的COPD稳定期患者126例作为研究对象,进行...目的:探究经皮神经穴位电刺激对慢性阻塞性肺疾病(Chronic obstructive pulmonary disease,COPD)稳定期患者临床疗效、肺功能及急性加重风险的影响。方法:选取2021年12月~2022年12月来我院就诊的COPD稳定期患者126例作为研究对象,进行前瞻性、单盲、随机、安慰剂对照研究试验,采取随机数字表法分为经穴治疗组33例、非经非穴组32例、假针组29、对照组31例。观察并比较四组治疗前后肺功能(FVC%、FEV 1 %、FEV 1 /FVC)、呼吸困难问卷(modified Medical Research Council,mMRC)评分、慢阻肺评估测试评分(COPD Assessment Test,CAT)、炎性因子水平(CRP、IL-6、TNF-ɑ、IL-8)、6min步行距离(6minute walking distance,6MWD)、急性加重风险(COPD中重度急性加重次数和住院次数)情况。结果:治疗后,四组FEV 1 /FVC、FVC%、FEV 1 %均升高,经穴治疗组均高于其他三组,差异有统计学意义( P <0.05)。治疗后,四组mMRC评分均下降,经穴治疗组均低于其他三组,差异有统计学意义( P <0.05)。治疗后,四组6MWD均延长、CAT评分均降低,经穴治疗组6MWD均长于其他三组、CAT评分均低于其他三组,差异有统计学意义( P <0.05)。治疗前6个月、治疗后6个月和治疗后6~12个月比较:四组COPD中重度急性加重次数和住院次数均下降,经穴治疗组均低于其他三组,差异有统计学意义( P <0.05)。治疗后,四组CRP、IL-6、TNF-ɑ和IL-8水平均下降,且经穴治疗组各指标水平均低于其他三组,差异有统计学意义( P <0.05)。四组不良反应发生率比较,差异无统计学意义( P >0.05)。结论:acu-TENS治疗可以明显改善COPD稳定期患者肺功能和呼吸困难程度,并下调患者体内炎性因子水平,同时降低COPD稳定期患者发生急性加重的风险,临床疗效尚可。展开更多
Literatures on pain intervention with transcutaneous electrical acupoint stimulation(TEAS)were collected by searching the databases both in Chinese and English,and summarized to understand the research progress of TEA...Literatures on pain intervention with transcutaneous electrical acupoint stimulation(TEAS)were collected by searching the databases both in Chinese and English,and summarized to understand the research progress of TEAS effects on pain mediators in recent years.This will provide a more objective and scientific theoretical basis for clinical practice of TEAS to treat pain syndrome,thus promoting the clinical application of TEAS.Our literature analysis indicated that TEAS effectively regulated the release levels of various pain factors such as prostaglandin,5-hydroxytryptamine,interleukins,substance P and tumor necrosis factor-αto achieve the analgesic effects by affecting the conduction pathways.TEAS is a safe,non-invasive and effective treatment for pain syndrome.However,further research is necessary due to the lack of rigor of the current clinical trial design.展开更多
Objective To examine the effect of acupuncture-like transcutaneous electrical nerve stimulation(ACUTENS)on labor pain in nulliparous women.Methods This randomized clinical trial was conducted at Razi Hospital in Qazvi...Objective To examine the effect of acupuncture-like transcutaneous electrical nerve stimulation(ACUTENS)on labor pain in nulliparous women.Methods This randomized clinical trial was conducted at Razi Hospital in Qazvin,Iran between January and July 2018.After the screening process,144 out of 184 pregnant women were selected by convenience sampling and assigned to an intervention group or a control group by the block randomization method.The intervention group received ACUTENS at Hegu(LI4),Shenmen(HT7),Sanyinjiao(SP6),and Neimadian(Extra)during various stages of delivery in addition to routine labor care at the delivery room.For the control group,the same routine labor care was performed alone.The severity of pain was assessed in the two groups using the visual analog scale(VAS).The data were analyzed using R software(ver.4.0.2)and repeated measurement analysis of variance.Results ACUTENS reduced the mean score of pain intensity in the first stage of labor in the intervention group more than that in the control group(P<0.001).Also,the mean scores of pain intensity in the second stage of labor,episiotomy,and one hour after delivery in the intervention group were significantly lower than those in the control group(P<0.001).Conclusion ACUTENS at Hegu(LI4),Shenmen(HT7),Sanyinjiao(SP6),and Neimadian(Extra)can decrease the intensity of labor pain in nulliparous women.It can be used as a non-pharmacological method for reducing pain in and after labor.展开更多
Objective:To explore the therapeutic efficacy and mechanism of transcutaneous electrical acupoint stimulation(TEAS)for menopausal insomnia.Methods:A total of 80 patients with menopausal insomnia were randomly divided ...Objective:To explore the therapeutic efficacy and mechanism of transcutaneous electrical acupoint stimulation(TEAS)for menopausal insomnia.Methods:A total of 80 patients with menopausal insomnia were randomly divided into a control group and an observation group,with 40 cases in each group.The patients in the control group received conventional Western medication treatment,and the patients in the observation group received TEAS on the basis of conventional Western medication treatment.The treatment for both groups lasted for 4 weeks.Before and after treatment,Pittsburgh sleep quality index(PSQI)and modified Kupperman scale were evaluated,and the serum levels of estradiol(E2)and follicular stimulating hormone(FSH)were measured.The therapeutic efficacy was evaluated after treatment.Results:After treatment,the total effective rate of the observation group was significantly higher than that of the control group(P<0.05);in the control group,the improvement of PSQI score was significant(P<0.05),while the change of modified Kupperman score was insignificant(P>0.05);the PSQI and Kupperman scores in the observation group were significantly improved after treatment(both P<0.05),and there were significant differences between the observation group and the control group in PSQI and Kupperman scores(both P<0.05).After treatment,the serum E2 and FSH levels in the control group were not statistically different from those before treatment(both P>0.05);the serum E2 level was significantly increased(P<0.05),and the FSH level was decreased(P<0.05)in the observation group after treatment,and the between-group differences in serum levels of E2 and FSH were significant(both P<0.05).Conclusion:TEAS plus conventional Western medication in treating menopausal insomnia is effective,and can significantly improve the symptoms of insomnia and menopause,which may be related to the regulation of serum E2 and FSH levels.展开更多
Objective:To observe the clinical effects of half puncture plus transcutaneous acupoint electric stimulation in the treatment of infantile facial paralysis. Methods:A total of 60 patients with infantile facial paral...Objective:To observe the clinical effects of half puncture plus transcutaneous acupoint electric stimulation in the treatment of infantile facial paralysis. Methods:A total of 60 patients with infantile facial paralysis were divided into a treatment group and a control group by the random digital table, 30 cases in each group. The treatment group was treated with half puncture plus transcutaneous acupoint electric stimulation. The control group was treated with routine acupuncture. Before and after treatment, House-Brackmann (H-B) grading was used to evaluate the sick children respectively. The total effective rates were compared between the two groups after treatment. Results:After 6-course treatments, the total effective rate was 96.5% in the treatment group and 80.0% in the control group, there was a statistical difference between the two groups (P〈0.05) in comparison of the total effective rate. After 6-course treatments, H-B scores were all elevated than those before treatment in the two groups (P〈0.05); there was a statistical difference between the two groups (P〈0.05). Conclusion:Half puncture plus transcutaneous acupoint electric stimulation is better than routine acupuncture in curative effect for infantile facial paralysis.展开更多
文摘目的:探究经皮神经穴位电刺激对慢性阻塞性肺疾病(Chronic obstructive pulmonary disease,COPD)稳定期患者临床疗效、肺功能及急性加重风险的影响。方法:选取2021年12月~2022年12月来我院就诊的COPD稳定期患者126例作为研究对象,进行前瞻性、单盲、随机、安慰剂对照研究试验,采取随机数字表法分为经穴治疗组33例、非经非穴组32例、假针组29、对照组31例。观察并比较四组治疗前后肺功能(FVC%、FEV 1 %、FEV 1 /FVC)、呼吸困难问卷(modified Medical Research Council,mMRC)评分、慢阻肺评估测试评分(COPD Assessment Test,CAT)、炎性因子水平(CRP、IL-6、TNF-ɑ、IL-8)、6min步行距离(6minute walking distance,6MWD)、急性加重风险(COPD中重度急性加重次数和住院次数)情况。结果:治疗后,四组FEV 1 /FVC、FVC%、FEV 1 %均升高,经穴治疗组均高于其他三组,差异有统计学意义( P <0.05)。治疗后,四组mMRC评分均下降,经穴治疗组均低于其他三组,差异有统计学意义( P <0.05)。治疗后,四组6MWD均延长、CAT评分均降低,经穴治疗组6MWD均长于其他三组、CAT评分均低于其他三组,差异有统计学意义( P <0.05)。治疗前6个月、治疗后6个月和治疗后6~12个月比较:四组COPD中重度急性加重次数和住院次数均下降,经穴治疗组均低于其他三组,差异有统计学意义( P <0.05)。治疗后,四组CRP、IL-6、TNF-ɑ和IL-8水平均下降,且经穴治疗组各指标水平均低于其他三组,差异有统计学意义( P <0.05)。四组不良反应发生率比较,差异无统计学意义( P >0.05)。结论:acu-TENS治疗可以明显改善COPD稳定期患者肺功能和呼吸困难程度,并下调患者体内炎性因子水平,同时降低COPD稳定期患者发生急性加重的风险,临床疗效尚可。
文摘Literatures on pain intervention with transcutaneous electrical acupoint stimulation(TEAS)were collected by searching the databases both in Chinese and English,and summarized to understand the research progress of TEAS effects on pain mediators in recent years.This will provide a more objective and scientific theoretical basis for clinical practice of TEAS to treat pain syndrome,thus promoting the clinical application of TEAS.Our literature analysis indicated that TEAS effectively regulated the release levels of various pain factors such as prostaglandin,5-hydroxytryptamine,interleukins,substance P and tumor necrosis factor-αto achieve the analgesic effects by affecting the conduction pathways.TEAS is a safe,non-invasive and effective treatment for pain syndrome.However,further research is necessary due to the lack of rigor of the current clinical trial design.
文摘Objective To examine the effect of acupuncture-like transcutaneous electrical nerve stimulation(ACUTENS)on labor pain in nulliparous women.Methods This randomized clinical trial was conducted at Razi Hospital in Qazvin,Iran between January and July 2018.After the screening process,144 out of 184 pregnant women were selected by convenience sampling and assigned to an intervention group or a control group by the block randomization method.The intervention group received ACUTENS at Hegu(LI4),Shenmen(HT7),Sanyinjiao(SP6),and Neimadian(Extra)during various stages of delivery in addition to routine labor care at the delivery room.For the control group,the same routine labor care was performed alone.The severity of pain was assessed in the two groups using the visual analog scale(VAS).The data were analyzed using R software(ver.4.0.2)and repeated measurement analysis of variance.Results ACUTENS reduced the mean score of pain intensity in the first stage of labor in the intervention group more than that in the control group(P<0.001).Also,the mean scores of pain intensity in the second stage of labor,episiotomy,and one hour after delivery in the intervention group were significantly lower than those in the control group(P<0.001).Conclusion ACUTENS at Hegu(LI4),Shenmen(HT7),Sanyinjiao(SP6),and Neimadian(Extra)can decrease the intensity of labor pain in nulliparous women.It can be used as a non-pharmacological method for reducing pain in and after labor.
文摘Objective:To explore the therapeutic efficacy and mechanism of transcutaneous electrical acupoint stimulation(TEAS)for menopausal insomnia.Methods:A total of 80 patients with menopausal insomnia were randomly divided into a control group and an observation group,with 40 cases in each group.The patients in the control group received conventional Western medication treatment,and the patients in the observation group received TEAS on the basis of conventional Western medication treatment.The treatment for both groups lasted for 4 weeks.Before and after treatment,Pittsburgh sleep quality index(PSQI)and modified Kupperman scale were evaluated,and the serum levels of estradiol(E2)and follicular stimulating hormone(FSH)were measured.The therapeutic efficacy was evaluated after treatment.Results:After treatment,the total effective rate of the observation group was significantly higher than that of the control group(P<0.05);in the control group,the improvement of PSQI score was significant(P<0.05),while the change of modified Kupperman score was insignificant(P>0.05);the PSQI and Kupperman scores in the observation group were significantly improved after treatment(both P<0.05),and there were significant differences between the observation group and the control group in PSQI and Kupperman scores(both P<0.05).After treatment,the serum E2 and FSH levels in the control group were not statistically different from those before treatment(both P>0.05);the serum E2 level was significantly increased(P<0.05),and the FSH level was decreased(P<0.05)in the observation group after treatment,and the between-group differences in serum levels of E2 and FSH were significant(both P<0.05).Conclusion:TEAS plus conventional Western medication in treating menopausal insomnia is effective,and can significantly improve the symptoms of insomnia and menopause,which may be related to the regulation of serum E2 and FSH levels.
文摘Objective:To observe the clinical effects of half puncture plus transcutaneous acupoint electric stimulation in the treatment of infantile facial paralysis. Methods:A total of 60 patients with infantile facial paralysis were divided into a treatment group and a control group by the random digital table, 30 cases in each group. The treatment group was treated with half puncture plus transcutaneous acupoint electric stimulation. The control group was treated with routine acupuncture. Before and after treatment, House-Brackmann (H-B) grading was used to evaluate the sick children respectively. The total effective rates were compared between the two groups after treatment. Results:After 6-course treatments, the total effective rate was 96.5% in the treatment group and 80.0% in the control group, there was a statistical difference between the two groups (P〈0.05) in comparison of the total effective rate. After 6-course treatments, H-B scores were all elevated than those before treatment in the two groups (P〈0.05); there was a statistical difference between the two groups (P〈0.05). Conclusion:Half puncture plus transcutaneous acupoint electric stimulation is better than routine acupuncture in curative effect for infantile facial paralysis.