Abstract： With the rapid development of assisted reproductive technology, various reproductive disorders have been effectively addressed. Acupuncture-like therapies, including electroacupuncture （EA） and transcutan...Abstract： With the rapid development of assisted reproductive technology, various reproductive disorders have been effectively addressed. Acupuncture-like therapies, including electroacupuncture （EA） and transcutaneous electrical acupoint stimulation （TEAS）, become more popular world-wide. Increasing evidence has demonstrated that EA and TEAS are effective in treating gynecological disorders, especially infertility. This present paper describes how to select acupoints for the treatment of infertility from the view of theories of traditional Chinese medicine and how to determine critical parameters of electric pulses of ENTEAS based on results from animal and clinical studies. It summarizes the principles of clinical application of EA/rEAS in treating various kinds of reproductive disorders, such as polycystic ovary syndrome （PCOS）, pain induced by oocyte retrieval, diminished ovarian reserve, embryo transfer, and oligosperrnia/ asthenospermia. The possible underlying mechanisms mediating the therapeutic effects of EA/TEAS in reproductive medicine are also examined.展开更多
文摘目的:研究经皮穴位电针刺激及早干预对老年髋部骨折术后认知功能及炎症因子的影响。方法:80岁以上髋部骨折患者40例,随机分为对照组(A组, 20例)和电刺激组(B组,20例)。两组患者均采用腰-硬联合麻醉。B组患者术前2 d选取百会穴和风池穴行经皮电针刺激,3次/d,30 min/次;麻醉操作完成后行穴位持续刺激至手术结束。A组患者仅在相应穴位贴电极未行电针刺激。于入院时、术后24、72 h 3个时点对患者进行MMSE评定,若术后评分降低一个标准差或以上者即认定发生术后认知功能障碍(POCD)。所有患者在入院时、术毕即刻、术后24和72 h抽取静脉血,测定血清IL-6、IL-10和S100β蛋白水平。结果:A组术后24、72 h POCD发生率分别为65%(13/20)和60%(12/20),高于B组的35%(7/20)和25%(5/20),差异有统计学意义(P<0.05);B组术后各时间点血清IL-6、IL-10和S100β蛋白水平均显著低于对照组同时间点,差异有统计学意义(P<0.05)。结论:及早经皮穴位电针干预有利于改善高龄老年髋部骨折术后的认知功能状态,有效降低患者POCD的发生率。这可能与抑制其血清IL-6、IL-10、S100B蛋白的过度表达、减轻患者脑损伤的程度有关。
基金Project supported by the Special Research Fund for the Public Welfare Industry of Health of China(No.201302013)
文摘Abstract： With the rapid development of assisted reproductive technology, various reproductive disorders have been effectively addressed. Acupuncture-like therapies, including electroacupuncture （EA） and transcutaneous electrical acupoint stimulation （TEAS）, become more popular world-wide. Increasing evidence has demonstrated that EA and TEAS are effective in treating gynecological disorders, especially infertility. This present paper describes how to select acupoints for the treatment of infertility from the view of theories of traditional Chinese medicine and how to determine critical parameters of electric pulses of ENTEAS based on results from animal and clinical studies. It summarizes the principles of clinical application of EA/rEAS in treating various kinds of reproductive disorders, such as polycystic ovary syndrome （PCOS）, pain induced by oocyte retrieval, diminished ovarian reserve, embryo transfer, and oligosperrnia/ asthenospermia. The possible underlying mechanisms mediating the therapeutic effects of EA/TEAS in reproductive medicine are also examined.
