Objective:To evaluate the factor of effective thrombus aspiration on outcomes during primary PCI in acute myocardial infarction patients.Methods:To select the AMI patients who undergoing primary PCI and receiving thro...Objective:To evaluate the factor of effective thrombus aspiration on outcomes during primary PCI in acute myocardial infarction patients.Methods:To select the AMI patients who undergoing primary PCI and receiving thrombus aspiration catheter during January 2008 to December 2008(n=226).Technical success of thrombectomy(device success)was defined as the ability of the device to cross the target lesion and to increase flow by>1.178 patients were enrolled in effective thrombus aspiration group,and 48 patients were enrolled in control group.To compare the immediate and in-hospital results between the two groups.Results:Age,sex,hypertension,LVEF,disease vessels,ischemic time,operate time,acute and subacute stent thrombosis,faster ST segment resolution were no significant differences between two groups(P> 0.05).Compared with the control group,smoke(44.9% vs 68.8%,P= 0.003),diabetes(18.5% vs 31.3%,P= 0.047),TIMI flow grade 0 pre-procedure(70.8% vs 85.4%,P= 0.043),no-reflow /slow flow post-PCI(2.2% vs 10.4%,P= 0.022),intracoronary Tirofiban(23.6% vs 64.2%,P=0.000)were decreased in the effective thrombus aspiration group.And TIMI flow grade 3 post-PCI(93.3% vs 77.1%,P=0.002),the rate of direct stent(44.9% vs 20.8%,P=0.003)were improved in the effective thrombus aspiration group.Logistic analysis showed that smoke(OR=1.551,95%CI:1.018-2.154,P= 0.012),diabetes(OR=1.132,95%CI:0.276-3.562,P= 0.044),TIMI flow grade 0 pre-procedure(OR=0.544,95%CI:0.368-1.911,P= 0.035)were independent factors of effective thrombus aspiration.Conclusion:Effective thrombus aspiration may improved TIMI flow grade 3 post-PCI and induce impaired myocardial perfusion,effect factors of effective thrombus aspiration should be paid more attention and reduced to achieved better clinical prognosis.展开更多
文摘Objective:To evaluate the factor of effective thrombus aspiration on outcomes during primary PCI in acute myocardial infarction patients.Methods:To select the AMI patients who undergoing primary PCI and receiving thrombus aspiration catheter during January 2008 to December 2008(n=226).Technical success of thrombectomy(device success)was defined as the ability of the device to cross the target lesion and to increase flow by>1.178 patients were enrolled in effective thrombus aspiration group,and 48 patients were enrolled in control group.To compare the immediate and in-hospital results between the two groups.Results:Age,sex,hypertension,LVEF,disease vessels,ischemic time,operate time,acute and subacute stent thrombosis,faster ST segment resolution were no significant differences between two groups(P> 0.05).Compared with the control group,smoke(44.9% vs 68.8%,P= 0.003),diabetes(18.5% vs 31.3%,P= 0.047),TIMI flow grade 0 pre-procedure(70.8% vs 85.4%,P= 0.043),no-reflow /slow flow post-PCI(2.2% vs 10.4%,P= 0.022),intracoronary Tirofiban(23.6% vs 64.2%,P=0.000)were decreased in the effective thrombus aspiration group.And TIMI flow grade 3 post-PCI(93.3% vs 77.1%,P=0.002),the rate of direct stent(44.9% vs 20.8%,P=0.003)were improved in the effective thrombus aspiration group.Logistic analysis showed that smoke(OR=1.551,95%CI:1.018-2.154,P= 0.012),diabetes(OR=1.132,95%CI:0.276-3.562,P= 0.044),TIMI flow grade 0 pre-procedure(OR=0.544,95%CI:0.368-1.911,P= 0.035)were independent factors of effective thrombus aspiration.Conclusion:Effective thrombus aspiration may improved TIMI flow grade 3 post-PCI and induce impaired myocardial perfusion,effect factors of effective thrombus aspiration should be paid more attention and reduced to achieved better clinical prognosis.
