前庭刺激对飞行员经穴电位影响的观察

为研究经穴电位测量技术在前庭刺激条件下评价生理状态的意义。８０名经鉴定飞行合格的空军飞行员闭眼端坐于转椅上以旋转剌激，同步测量左、右内关穴及左、右足三里穴经穴电位。结果显示：在恒速旋转５ｍｉｎ的过程中各时相经穴电位值与实验前比较无明显的变化（Ｐ＞０．０５），而在第６ｍｉｎ头动刺激下，所测经穴的电位值发生明显变化（Ｐ＜０．０５或０．０１），又以左侧经穴的电位值变化显著，呈现在前庭刺激下左右经相同经穴的电位明显失衡，经统计学处理有显著差异（Ｐ＜０．０５）。提示经穴电位有可能作为前庭刺激下评定生理状态的参考指标。症状与相应穴位的电位变化的相关性，尚需作进一步的研究。

视动刺激与低频振动条件下经穴电位的变化

为探索经络经穴电位（ＡＰ）测量技术在航空航天医学研究中的应用价值，睁眼坐位视动和低频振动条件下，观察了２２名１８～２２岁男性健康青年经络经穴电位的变化，测定了经络井穴的皮肤电位。结果表明：在视动刺激条件下，胃经络井穴电位左右明显失衡，症状愈重的被试者井穴电位失衡愈明显。在低频振动刺激条件下经络井穴电位也发生了变化，唯在８ＨＺ—０．６６Ｇ井穴电位变化明显。但不同刺激条件下变化不尽相同。提示：经络经穴电位技术在航空航天医学研究和实践中有一定的应用价值。

基于小波消噪与关联维数的经穴电位信号研究

穴位点在中医邻域具有相对于非穴位点的特殊治疗效果。为此,提出一种基于小波去噪和关联维数的经穴电位信号分析方法。采集大陵、曲泽和尺泽3个穴位点及其附近的非穴位点电位信号,小波去噪后进行混沌特征分析,求取关联维数和最大李雅普诺夫指数,观察穴位点和非穴位点特征差异。实验结果表明,穴位点电位的关联维数高于其附近非穴位点电位的关联维数。

Electro-acupuncture Combined with Plum-blossom Needle Tapping for Treatment of Supraorbital Neuritis—A Clinical Observation of 59 Cases

Supraorbital neuritis is an inflammatory infection of the supraorbital nerve due to invasion of viruses. The authors have treated 59 such cases by means of electroacupuncture combined with plum-blossom needle tapping, with satisfactory therapeutic results reported as follows.

SEGMENTAL DISTRIBUTION OF AFFERENT ELECTRO-ACUPUNCTURE SIGNALS FROM ACUPOINTS OF THE PERICARDIUM MERIDIAN IN THE RAT

Objective: To observe the segmental distribution of afferent Electroacupuncture (EA) signals from acupoints of the Pericardium (PC) Meridian and try to analyze the relative specificity of running route of PC Meridian.Methods: A total of 85 Wistar rats anesthetized with mixed solution of Chloralose (5 mg/100 g) and Urethane (42 mg/100g) were used in this study. Under microscopic observation, the micro-filaments of the distal end of the dorsal root were carefully separated after tearing the spinal pia mater to attach to a recording electrode. The reference electrode was placed beneath the skin of the incision. Two caudal and two rostral dorsal roots near the recorded one were cut off separately. Electrical activity of the isolated micro-filaments was observed before and after EA of "Daling" (PC 7) -"Jianshi" (PC 5), "Quze" (PC 3) of PC Meridian, "Yangchi"(TE 4)- "Zhigou" (TE 6), "Tianjing" (TE 10)-" Qin-glengyuan" (TE 11) of the Triple Energizer (TE) Meridian with electric current 1 mA and 2 mA and double pulses. Results: ① After EA (1 mA) of "Daling"(PC 7)-"Jianshi"(PC 5), the firing rates of 3 out of 10 (33.3%) micro-filaments in C5 segment, 5 out of 10 (50.0%) in C6, 7 out of 10 (70.0%) in 07, 3 out of 10 (30.0%) in C8 and 3 out of 13 (23. 1%) in T1 increased considerably；and after EA of "Quze" (PC 3), those of 3/10 of C5, 4/10 of C6, 6/10 of C7, 3/10 of C8, and 3/10 of T1 increased significantly. ② After EA (1 mA) of "Yangchi"(TE 4)- "Zhigou" (TE 6) and "Tianjing" (TE 10)- "Qinglengyuan" (TE 11). the firing rates of 2/10, 2/10 of micro-filaments In C5, 7/10, 3/10 of C6, 5/10 and 4/10 of C7, 1/10 and 1/10 of C8, and 2/13 and 1/10 of T1 increased significantly. It indicates that C7 dorsal root may play the first important role in conveying EA signals from PC Meridian acupoints to the spinal cord, while C6 and C7 may be mainly responsible for conveying EA signals from TE Meridian acupoints to the spinal cord. Conclusion: The peripheral afferent pathway for transmitting EA signals from PC Meridian acupoints probably has a relative specificity.

Advances of studies on relieving of exercise-induced fatigue by transcutaneous electrical acupoint stimulation

The occurrence of exercise-induced fatigue can be delayed and exercise endurance can be strengthened by removing lactic acid, decreasing serum creatine kinase, elevating hemoglobin, maintaining blood glucose, eliminating free radical, regulating amino acid metabolism and retaining heart rate with transcutaneous electrical acupoint stimulation （TEAS）. Problems in the above researching field are generalized in this paper. For instance, the point selection is relatively simple; the selection of wave band, frequency and duration during the application of TEAS apparatus are not unified; and observation indices mainly remained in the aspect of biochemistry. It also prospects the future directions of TEAS relieving exercise-induced fatigue including selecting acupuncture point by differentiation of symptoms and signs, setting uniform standards for TEAS, and studying the mechanisms of TEAS relieving exercise-induced fatigue by testing gonadal axis, adrenal axis, gene and protein .

Use of electroacupuncture and transcutaneous electrical acupoint stimulation in reproductive medicine:a group consensus

Abstract： With the rapid development of assisted reproductive technology, various reproductive disorders have been effectively addressed. Acupuncture-like therapies, including electroacupuncture （EA） and transcutaneous electrical acupoint stimulation （TEAS）, become more popular world-wide. Increasing evidence has demonstrated that EA and TEAS are effective in treating gynecological disorders, especially infertility. This present paper describes how to select acupoints for the treatment of infertility from the view of theories of traditional Chinese medicine and how to determine critical parameters of electric pulses of ENTEAS based on results from animal and clinical studies. It summarizes the principles of clinical application of EA/rEAS in treating various kinds of reproductive disorders, such as polycystic ovary syndrome （PCOS）, pain induced by oocyte retrieval, diminished ovarian reserve, embryo transfer, and oligosperrnia/ asthenospermia. The possible underlying mechanisms mediating the therapeutic effects of EA/TEAS in reproductive medicine are also examined.

Overview of reported transcutaneous electrical acupoint stimulation effects on pain mediators

Literatures on pain intervention with transcutaneous electrical acupoint stimulation(TEAS)were collected by searching the databases both in Chinese and English,and summarized to understand the research progress of TEAS effects on pain mediators in recent years.This will provide a more objective and scientific theoretical basis for clinical practice of TEAS to treat pain syndrome,thus promoting the clinical application of TEAS.Our literature analysis indicated that TEAS effectively regulated the release levels of various pain factors such as prostaglandin,5-hydroxytryptamine,interleukins,substance P and tumor necrosis factor-αto achieve the analgesic effects by affecting the conduction pathways.TEAS is a safe,non-invasive and effective treatment for pain syndrome.However,further research is necessary due to the lack of rigor of the current clinical trial design.

Effect of acupuncture-like transcutaneous electrical nerve stimulation on labor pain in nulliparous women:a randomized controlled trial

Objective To examine the effect of acupuncture-like transcutaneous electrical nerve stimulation(ACUTENS)on labor pain in nulliparous women.Methods This randomized clinical trial was conducted at Razi Hospital in Qazvin,Iran between January and July 2018.After the screening process,144 out of 184 pregnant women were selected by convenience sampling and assigned to an intervention group or a control group by the block randomization method.The intervention group received ACUTENS at Hegu(LI4),Shenmen(HT7),Sanyinjiao(SP6),and Neimadian(Extra)during various stages of delivery in addition to routine labor care at the delivery room.For the control group,the same routine labor care was performed alone.The severity of pain was assessed in the two groups using the visual analog scale(VAS).The data were analyzed using R software(ver.4.0.2)and repeated measurement analysis of variance.Results ACUTENS reduced the mean score of pain intensity in the first stage of labor in the intervention group more than that in the control group(P<0.001).Also,the mean scores of pain intensity in the second stage of labor,episiotomy,and one hour after delivery in the intervention group were significantly lower than those in the control group(P<0.001).Conclusion ACUTENS at Hegu(LI4),Shenmen(HT7),Sanyinjiao(SP6),and Neimadian(Extra)can decrease the intensity of labor pain in nulliparous women.It can be used as a non-pharmacological method for reducing pain in and after labor.

Clinical Observation of Electroacupuncture and Acupoint Injection in Treating Common Fibular Nerve Paralysis

Objective： To observe the clinical efficacy of combined electroacupuncture and nerve growth factor（NGF） injection at acupoints in the treatment of common fibular nerve paralysis and provide evidences for integrative Chinese ＆ western medicine against diabetic peripheral neuropathy（DPN）. Methods： Forty subjects were randomized into two groups and treated by routine therapy. Moreover, treatment group was given electro-acupuncture and NGF injection; and control group was given herbal suffocation, oral Dibazol and compound vitamin B and Mecobalamin Injection. The clinical symptoms and nerve conduction velocity were observed and compared. Results： The cure rate was higher in treatment group than in control group （P〈0.05）; after treatment, the nerve conduction velocity was improved in both groups （P〈0.01）, with a significant improvement in treatment group than in control group （P〈0.01）. Conclusion： Combined electro-acupuncture and NGF injection at acupoints is quite effective in the treatment of common fibular nerve paralysis.

Observation on therapeutic effect of half puncture plus transcutaneous acupoint electric stimulation for infantile facial paralysis

Objective：To observe the clinical effects of half puncture plus transcutaneous acupoint electric stimulation in the treatment of infantile facial paralysis. Methods：A total of 60 patients with infantile facial paralysis were divided into a treatment group and a control group by the random digital table, 30 cases in each group. The treatment group was treated with half puncture plus transcutaneous acupoint electric stimulation. The control group was treated with routine acupuncture. Before and after treatment, House-Brackmann （H-B） grading was used to evaluate the sick children respectively. The total effective rates were compared between the two groups after treatment. Results：After 6-course treatments, the total effective rate was 96.5% in the treatment group and 80.0% in the control group, there was a statistical difference between the two groups （P〈0.05） in comparison of the total effective rate. After 6-course treatments, H-B scores were all elevated than those before treatment in the two groups （P〈0.05）; there was a statistical difference between the two groups （P〈0.05）. Conclusion：Half puncture plus transcutaneous acupoint electric stimulation is better than routine acupuncture in curative effect for infantile facial paralysis.

Efficacy of transcutaneous electrical acupoint stimulation(TEAS)for menopausal insomnia and its effect on serum hormone levels

Objective:To explore the therapeutic efficacy and mechanism of transcutaneous electrical acupoint stimulation(TEAS)for menopausal insomnia.Methods:A total of 80 patients with menopausal insomnia were randomly divided into a control group and an observation group,with 40 cases in each group.The patients in the control group received conventional Western medication treatment,and the patients in the observation group received TEAS on the basis of conventional Western medication treatment.The treatment for both groups lasted for 4 weeks.Before and after treatment,Pittsburgh sleep quality index(PSQI)and modified Kupperman scale were evaluated,and the serum levels of estradiol(E2)and follicular stimulating hormone(FSH)were measured.The therapeutic efficacy was evaluated after treatment.Results:After treatment,the total effective rate of the observation group was significantly higher than that of the control group(P<0.05);in the control group,the improvement of PSQI score was significant(P<0.05),while the change of modified Kupperman score was insignificant(P>0.05);the PSQI and Kupperman scores in the observation group were significantly improved after treatment(both P<0.05),and there were significant differences between the observation group and the control group in PSQI and Kupperman scores(both P<0.05).After treatment,the serum E2 and FSH levels in the control group were not statistically different from those before treatment(both P>0.05);the serum E2 level was significantly increased(P<0.05),and the FSH level was decreased(P<0.05)in the observation group after treatment,and the between-group differences in serum levels of E2 and FSH were significant(both P<0.05).Conclusion:TEAS plus conventional Western medication in treating menopausal insomnia is effective,and can significantly improve the symptoms of insomnia and menopause,which may be related to the regulation of serum E2 and FSH levels.

Effect of transcutaneous electrical nerve stimulation at acupoints on patients with type 2 diabetes mellitus:a randomized controlled trial

OBJECTIVE:To examine whether transcutaneous electric nerve stimulation at acupoints(Acu-TENS)improved the biochemical and physical indices of patients with type 2 diabetes mellitus(T2DM).METHODS:Ninety subjects with T2DM were divided randomly into a control group(n = 30),aerobic exercise group(n- 30),or Acu-TENS group(n = 30).In addition to conventional diabetes drug treatment,patients in the Acu-TENS group received acupoint stimulation,the aerobic exercise group engaged in walking exercises,and the control group was given sham electrical stimulation.All groups were treated for 30 min for each session and five times a week for 2 months.The indices of glycosylated hemoglobin,2 h postprandial glucose,fasting serum insulin,triglyceride,total cholesterol,and body mass index were assessed at pre-treatment,post-treatment,and follow-up,which was 2 months after treatment.RESULTS:The indices of the control group were not changed(P > 0.05) at the three time points.At the pre-treatment measurement,there were significant differences(P > 0.05) in indices among the three groups.At post-treatment,each index of the two groups was lower than that of the control group(P < 0.05),and improved in comparison with the pre-treatment measurement(P < 0.05).In follow-up,each index of the aerobic exercise group and Acu-TENS group increased,but was still decreased compared with the pre-treatment value(P < 0.05),excluding body mass index.CONCLUSION:Acu-TENS could improve the state of patients with T2 DM and be used as a therapy in clinical application.