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双电极绑定技术记录在体大鼠海马CA1区长时程增强 被引量:4
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作者 郭芬 武美娜 +1 位作者 景玮 祁金顺 《中国应用生理学杂志》 CAS CSCD 北大核心 2007年第3期381-384,共4页
目的:探讨双电极绑定条件下记录大鼠在体海马CA1区长时程增强的可行性。方法:雄性Wistar大鼠乌拉坦麻醉;脑立体定位仪上埋置脑室导管;安装自制的刺激/记录绑定电极;引导基础性场兴奋性突触后电位(fEP-SP);强直刺激诱导长时程增强(LTP)... 目的:探讨双电极绑定条件下记录大鼠在体海马CA1区长时程增强的可行性。方法:雄性Wistar大鼠乌拉坦麻醉;脑立体定位仪上埋置脑室导管;安装自制的刺激/记录绑定电极;引导基础性场兴奋性突触后电位(fEP-SP);强直刺激诱导长时程增强(LTP)。结果:绑定后的刺激和记录电极能可靠地引起海马CA1区fEPSP,fEPSP的出现率几乎100%;基础性fEPSP记录可保持长时间稳定;高频刺激成功诱导出LTP并维持达3h以上,诱导率约67%;双脉冲易化记录稳定、可靠;脑室注射β淀粉样蛋白(Aβ)对LTP显示出明显的压抑作用。结论:采用双电极绑定技术进行在体海马LTP记录简便易行、节省资源、引导fEPSP和诱导LTP的成功率较高,有望成为一项重要的研究学习和记忆机制的电生理辅助手段。 展开更多
关键词 长时程增强 绑定电极 海马 在体记录
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Analysis of Relation Between Binding and Magnetic Force in Generators in Extreme Conditions
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《Electricity》 2013年第1期26-30,共5页
Because of the action of strong magnetic forces, it's difficult to avoid end winding vibration in the large turbo-generator stator. Sometimes it leads to the occurrence of accidents and affects the normal operatio... Because of the action of strong magnetic forces, it's difficult to avoid end winding vibration in the large turbo-generator stator. Sometimes it leads to the occurrence of accidents and affects the normal operation of the generator. This paper firstly lays out the calculation method for end winding magnetic force. Second, based on the structure of large machines, the natural vibration frequency equation and forced oscillation equation is set up. Third, through the analysis of magnetic force calculation and vibration on the end winding of turbo-generator, it will be shown that the end winding vibration is related to the magnetic force and the position of winding binds as well as binding tightness. We can ease the winding vibration by distributing binding position appropriately or add more bindings, and test the concept through experimental data. 展开更多
关键词 TURBO-GENERATOR vibration magnetic force winding binding
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