To enhance the accuracy and efficiency of bridge damage identification,a novel data-driven damage identification method was proposed.First,convolutional autoencoder(CAE)was used to extract key features from the accele...To enhance the accuracy and efficiency of bridge damage identification,a novel data-driven damage identification method was proposed.First,convolutional autoencoder(CAE)was used to extract key features from the acceleration signal of the bridge structure through data reconstruction.The extreme gradient boosting tree(XGBoost)was then used to perform analysis on the feature data to achieve damage detection with high accuracy and high performance.The proposed method was applied in a numerical simulation study on a three-span continuous girder and further validated experimentally on a scaled model of a cable-stayed bridge.The numerical simulation results show that the identification errors remain within 2.9%for six single-damage cases and within 3.1%for four double-damage cases.The experimental validation results demonstrate that when the tension in a single cable of the cable-stayed bridge decreases by 20%,the method accurately identifies damage at different cable locations using only sensors installed on the main girder,achieving identification accuracies above 95.8%in all cases.The proposed method shows high identification accuracy and generalization ability across various damage scenarios.展开更多
Aim To obtain an optimizing range of the main configuration parameters of double swirls combustion system (DSCS) Methods To analyze the influence of DS combustion cham-ber configuration parameters on fuel spray and mi...Aim To obtain an optimizing range of the main configuration parameters of double swirls combustion system (DSCS) Methods To analyze the influence of DS combustion cham-ber configuration parameters on fuel spray and mixing by means of the fuel jet developmentperiphery charts obtained by the high speed photography with a modeling test device deve-loped by authors,and to examine it by the tests on a single cylinder diesel engine.Resultsand Conclusion The mixing process can be divided into four phases.The optimizing range of the ration of the inner chamber diameter to the cylinder bore,d2/D,is 0.4-0.7; and the outerchamber diameter,d1 the height of the circular ridge to the piston top face,h1,the radius of outer/inner chamber circle,R1,R2 ,the max depth of outer/inner chamber bowl,H1,H2,etc. are also important展开更多
The finding of the compound structure of a new four-scrolls chaotic system is reported, which is obtained by merging together two symmetrical attractors. And the two symmetrical attractors are generated only by adding...The finding of the compound structure of a new four-scrolls chaotic system is reported, which is obtained by merging together two symmetrical attractors. And the two symmetrical attractors are generated only by adding a constant gain to the original system. Also, the forming procedure of the new four-scrolls chaotic attractor is explored and the relation between the constant gain and the properties of the system is given.展开更多
The molecular structure of a higher plant myosin with two 174 kD heavy chains purified from the tendrils of Luffa cylindrica (L.) Roem. was viewed by electron microscopy. The myosin exhibited actin_activated MgATP...The molecular structure of a higher plant myosin with two 174 kD heavy chains purified from the tendrils of Luffa cylindrica (L.) Roem. was viewed by electron microscopy. The myosin exhibited actin_activated MgATPase activity and could be recognized immunologically by a monoclonal antibody against the skeletal muscle myosin. Electron micrographs of rotary shadowed images of this protein revealed that it had two heads with size and shape similar to those of the skeletal muscle myosin and a relatively short tail in comparison with the conventional myosin. Luffa tendril actin filaments were also visualized and occasionally other Luffa myosin_like proteins with globular structure at the tail ends were also observed. The structural similarity and immunological cross reactivity with antibodies against muscle myosin demonstrate that the 174 kD Luffa tendril myosin is a double_headed myosin. The possible involvement of myosin_actin interactions in Luffa tendril contact coiling will be the subject of further research.展开更多
The experiment was performed to evaluate the progenies of plant lines transgenic for auxin synthesis genes derived from Ri T-DNA. Four lines of the transgenic plants were selfcrossed and the foreign auxin genes in pla...The experiment was performed to evaluate the progenies of plant lines transgenic for auxin synthesis genes derived from Ri T-DNA. Four lines of the transgenic plants were selfcrossed and the foreign auxin genes in plants of T5 generation were confirmed by Southern hybridization. Two lines, D1232 and D1653, showed earlier folding of expanding leaves than untransformed line and therefore had early initiation of leaf y head. Leaf cuttings derived from plant of transgenic line D1653 produced more adventitious roots than the control whereas the cuttings from folding leaves had much more roots than rosette leaves at folding stage, and the cuttings from head leaves had more roots than rosette leaves at heading stage. It is demonstrated that early folding of transgenic leaf may be caused by the relatively higher concentration of auxin. These plant lines with auxin transgenes can be used for the study of hormonal regulation in differentiation and development of plant organs nd for the breeding of new varietywith rapid growth trait.展开更多
Flat Steel Ribbon Wound Pressure Vessels (FSRWPVs) are used in many important industry areas. There is no such kind of pressure vessel exploding on operation for its reasonable structure design. Many explosion experim...Flat Steel Ribbon Wound Pressure Vessels (FSRWPVs) are used in many important industry areas. There is no such kind of pressure vessel exploding on operation for its reasonable structure design. Many explosion experiments on Flat Steel Ribbon Wound Pressure Vessel showed that their limited load pressure is related to the winding angle of the steel ribbons. FSRWPVs with reasonable winding angle have better security and lower cost. Reasonable angels given at the end of this paper facilitate engineering design.展开更多
In view of the problems of multi-scale changes of segmentation targets,noise interference,rough segmentation results and slow training process faced by medical image semantic segmentation,a multi-scale residual aggreg...In view of the problems of multi-scale changes of segmentation targets,noise interference,rough segmentation results and slow training process faced by medical image semantic segmentation,a multi-scale residual aggregation U-shaped attention network structure of MAAUNet(MultiRes aggregation attention UNet)is proposed based on MultiResUNet.Firstly,aggregate connection is introduced from the original feature aggregation at the same level.Skip connection is redesigned to aggregate features of different semantic scales at the decoder subnet,and the problem of semantic gaps is further solved that may exist between skip connections.Secondly,after the multi-scale convolution module,a convolution block attention module is added to focus and integrate features in the two attention directions of channel and space to adaptively optimize the intermediate feature map.Finally,the original convolution block is improved.The convolution channels are expanded with a series convolution structure to complement each other and extract richer spatial features.Residual connections are retained and the convolution block is turned into a multi-channel convolution block.The model is made to extract multi-scale spatial features.The experimental results show that MAAUNet has strong competitiveness in challenging datasets,and shows good segmentation performance and stability in dealing with multi-scale input and noise interference.展开更多
The present work aimed to investigate the effect of coiling process conditions on microstructure development in a low-Si content TRIP (transformation-induced plasticity)-assisted steel after thermomechanical process...The present work aimed to investigate the effect of coiling process conditions on microstructure development in a low-Si content TRIP (transformation-induced plasticity)-assisted steel after thermomechanical processing. In this framework, compression samples which were deformed above Tnr and then intercritically annealed were held isothermally for different durations at temperatures below bainite transformation start temperature. Microstructure of samples were characterized by optical and electron microscopy, XRD (X-ray diffraction) and M6ssbauer spectroscopy. The results indicated that due to low-silicon content of the present steel, the incomplete bainite reaction phenomena was not observed and, hence, the maximum carbon enrichment of residual austenite was achieved in the samples which held for short durations. It was also shown that the maximum carbon enrichment and volume fraction of residual austenite were achieved at intermediate bainite hold temperature of 450 ℃ as the result of competing phenomena, such as microstructural refinement, dislocation density, carbide precipitation and growth.展开更多
AIM:To study the epidemiologic indicators of uptake and characteristic colonoscopic findings in the Croatian National Colorectal Cancer Screening Program.METHODS:Colorectal cancer(CRC) was the second leading cause of ...AIM:To study the epidemiologic indicators of uptake and characteristic colonoscopic findings in the Croatian National Colorectal Cancer Screening Program.METHODS:Colorectal cancer(CRC) was the second leading cause of cancer mortality in men(n = 1063,49.77/100 000),as well as women(n = 803,34.89/100 000) in Croatia in 2009.The Croatian National CRC Screening Program was established by the Ministry of Health and Social Welfare,and its implementation started in September,2007.The coordinators were recruited in each county institute of public health with an obligation to provide fecal occult blood testing(FOBT) to the participants,followed by colonoscopy in all positive cases.The FOBT was performed by hypersensitive guaiac-based Hemognost card test(Biognost,Zagreb).The test and short questionnaire were delivered to the home addresses of all citizens aged 50-74 years consecutively during a 3-year period.Each participant was required to complete the questionnaire and send it together with the stool specimen on three test cards back to the institute for further analysis.About 4% FOBT positive cases are expected in normal risk populations.A descriptive analysis was performed.RESULTS:A total of 1 056 694 individuals(born between 1933-1945 and 1952-1957) were invited to screening by the end of September 2011.In total,210 239(19.9%) persons returned the envelope with a completed questionnaire,and 181 102 of them returned it with a correctly placed stool specimen on FOBT cards.Until now,12 477(6.9%),FOBT-positive patients have been found,which is at the upper limit of the expected values in European Guidelines for Quality Assurance in CRC Screening and Diagnosis [European Union(EU) Guidelines].Colonoscopy was performed in 8541 cases(uptake 66%).Screening has identified CRC in 472 patients(5.5% of colonoscopied,3.8% of FOBT-positive,and 0.26% of all screened individuals).This is also in the expected range according to EU Guidelines.Polyps were found and removed in 3329(39% of colonoscopied) patients.The largest number of polyps were found in the left half of the colon:64%(19%,37% and 8% in the rectum,sigma,and descendens,respectively).The other 36% were detected in the proximal part(17% in the transverse colon and 19% in ceco-ascending colon).Small polyps in the rectum(5-10 mm in diameter),sigmoid and descending colon were histologically found to be tubular adenomas in 60% of cases,with a low degree of dysplasia,and 40% were classified as hyperplastic.Polyps of this size in the transverse or ceco-ascending colon in almost 20% had a histologically villous component,but still had a low degree of dysplasia.Polyps sized 10-20 mm in diameter were in 43% cases tubulovillous,and among them,32% had areas with a high degree of dysplasia,especially those polyps in the cecoascending or transverse part.The characteristics of the Croatian CRC Screening National Program in the first 3 years were as follows:relatively low percentage of returned FOBT,higher number of FOBT-positive persons but still in the range for population-based programs,and higher number of pathologic findings(polyps and cancers).CONCLUSION:These results suggest a need for intervention strategies that include organizational changes and educational activities to improve awareness of CRC screening usefulness and increase participation rates.展开更多
This study aims at investigating the effects of the pre-task planning mode on listening comprehension of Chinese EFL (English as a foreign language) learners as well as students' opinions towards the pre-task plann...This study aims at investigating the effects of the pre-task planning mode on listening comprehension of Chinese EFL (English as a foreign language) learners as well as students' opinions towards the pre-task planning mode Three step~., namely, concept mapping, strategic planning, as well as rehearsal, are employed in the pre-task planning mode in the present study. There are altogether 40 second-year English majors participated in the present study, and they are randomly assigned into the experimental group and the control group. The instruments employed in the present study to achieve the research purposes include the listening comprehension test, the teacher's log, the students' opinion questionnaires, the students' open-ended questionnaires, and the semi-structured interviews. Research findings revealed that there were significant main effects on the listening comprehen,;ion of Chinese EFL learners after the training by the pre-task planning mode. Moreover, the students held positive attitudes towards the pre-task planning mode展开更多
Objective: The aim of this study was to analyze factors of psychological disorder experienced by 98 cancer patients and to probe into intervention measures in accordance with the corresponding bad psychological facto...Objective: The aim of this study was to analyze factors of psychological disorder experienced by 98 cancer patients and to probe into intervention measures in accordance with the corresponding bad psychological factors. Methods: A questionnaire survey was conducted in the test group (n = 98) by filling out a symptom checklist 90 (SCL-90). And then the survey result was compared with the normal group (n = 1388) contained in relevant references. Results: Except for hostile factor that was similar to normal level (P 〉 0.05), other 8 factors were higher than in normal group (P 〈 0.01). And the cancer patients were classified with the survey results. Conclusion: Compared with normal persons, cancer patients have more psychological problems and related intervention measures are sought necessarily to improve the quality of life, to advance the immune function and to prolong the survival time of patients.展开更多
AIM: TO investigate the role of Lactobacillus crispatus (L. crispatus) strain China Center for Type Culture Col- lection (CCTCC) M206119 in intestinal inflammation.METHODS: Forty 8-wk-old Balb/c mice (20± ...AIM: TO investigate the role of Lactobacillus crispatus (L. crispatus) strain China Center for Type Culture Col- lection (CCTCC) M206119 in intestinal inflammation.METHODS: Forty 8-wk-old Balb/c mice (20± 2 g) were divided into four groups of 10 mice each. Three groups that had received dextran sulfate sodium (DSS) were administered normal saline, sulfasalazine or CCTCC M206119 strain, and the fourth group received none of these. We assessed the severity of colitis using a disease activity index, measured the colon length and weight, collected stools and mesenteric lymph nodes for bacterial microflora analysis. One centimeter of the proximal colon, middle colon and distal colon were collected and fixed in 10% buffered formalin, dehydrated in ethanol, and embedded in paraffin. Interleukin (IL)- 1β, IL-6 and tumor necrosis factor (TNF)-α expression was detected using reverse transcription polymerase chain reaction. Protective factors zonula occludens (ZO)-1 and β-defensin 2 were detected by immunoblot-ting. The features of CCTCC M206119 strain were identified based on morphology, biochemical profile, and 16S RNA sequencing.RESULTS: DSS-colitis animals treated with CCTCC M206119 had markedly more severe disease, with greater weight loss, diarrhea, fecal bleeding, and shortened colon length. In addition, the CCTCC-M206119- treated group had comparatively higher histologi- cal scores and more neutrophil infiltration than the controls. Expression of protective factors ZO-1 and β-defensin 2 was downregulated due to destruction of the mucosal barrier after CCTCC M206119 strain treatment. An in vitro assay demonstrated that CCTCC M206119 strain increased the nuclear translocation of nuclear factor-κB in epithelial cells. Intestinal proinflam- matory or anti-inflammatory cytokine responses were evaluated. Proinflammatory colonic cytokine (IL-Iβ, IL-6 and TNF-α) levels were clearly increased in CCTCC- M206119-treated animals, whereas anti-inflammatory colonic cytokine (IL-10) level was lowered compared with saline or 5-aminosalicylic-acid-treated DSS-colitis mice. Next, CCTCC M206119 strain was characterized as 1. crispatus by microscopic morphology, biochemical tests and 16S rRNA gene level.CONCLUSION: Not all lactobacilli are beneficial for in- testinal inflammation, and L. crispatus CCTCC M206119 strain is involved in exacerbation of intestinal inflamma- tion in DSS-colitis mice.展开更多
This study attempts to examine the conceptual and political bases of Bangsamoro women's participation on politics in terms of electoral, policy-making, and peace processes in Lanao del Sur. The descriptive correlatio...This study attempts to examine the conceptual and political bases of Bangsamoro women's participation on politics in terms of electoral, policy-making, and peace processes in Lanao del Sur. The descriptive correlation method was used, which utilized a survey questionnaire as the primary source in acquiring the data. The findings showed that the majority of the respondents were young, most of them were married and had finished elementary degree. It was observed that their participation in electoral, policy-making, and peace processes was high but vote buying, political ideology, and corruption were considered to be their problems. Despite cultural barriers, a clear understanding of their role as Muslim woman can increase their participation. Hence, total reform in the government as well as the Barangay should be done including their participation for the training programs on leadership, accountability and transparency, human and political rights awareness as well as the Shariah Law and the Philippine Constitution. Political party system that has a strong alliance to other political parties shall also be established in order to assure their participation. Linkages to other civil society like class-based organizations, occupation-based associations, and interest-based societies shall be tapped by the leaders of Bangsamoro women.展开更多
Acquisition of speaking Turkish students since skills is among the most essential language skills for students currently, especially among language competency is measured through speaking. Every language learner desir...Acquisition of speaking Turkish students since skills is among the most essential language skills for students currently, especially among language competency is measured through speaking. Every language learner desires to acquire correct communicative skills and fluency in speaking, while teachers aim to give the necessary education in speaking, as well. This study reveals the essence of acquiring speaking competency for learners, and how important it is to teach speaking skills with correct methods and methodology. With the questionnaire analysis on Turkish students and teachers at a Turkish university, the theoretical knowledge on "essence" is blended with the questionnaire results provided from students and teachers in order to emphasize the necessity and reach more practical solutions for the current need of learning and teaching speaking.展开更多
Despite the presence of bye-laws, solid waste management continues to be an issue in Mbarara municipality with households and businesses continuing to dump solid waste on open plots, low-lying areas, public spaces and...Despite the presence of bye-laws, solid waste management continues to be an issue in Mbarara municipality with households and businesses continuing to dump solid waste on open plots, low-lying areas, public spaces and rivers, or simply burning it in their backyards. This qualitative study aimed at establishing reasons as to why there was still improper solid waste management in Mbarara municipality and also establishing its constraints. Tools used included semi-structured questionnaires, observation and photographs. Two hundred and ninety-four participants (24 solid waste collectors, eight municipal council members and 262 community members) participated in the study. The study revealed both insufficient budget (87.5%) and insufficient equipment (50%) as the most common policy challenges in implementing proper solid waste management. Solid waste collectors not being comfortable with their salaries (79.2%), limited sensitization regarding solid waste management (66%) and limited necessary tools (58.3%) as other challenges faced by solid waste management policy makers and implementers and finally, community members having limited awareness about laws governing solid waste management (61.1%). In conclusion, insufficient budget, insufficient equipment, poor motivation and inadequate sensitization were found to be the major reasons as to why there was still improper solid waste management in Mbarara municipality, western Uganda.展开更多
基金The National Natural Science Foundation of China(No.52361165658,52378318,52078459).
文摘To enhance the accuracy and efficiency of bridge damage identification,a novel data-driven damage identification method was proposed.First,convolutional autoencoder(CAE)was used to extract key features from the acceleration signal of the bridge structure through data reconstruction.The extreme gradient boosting tree(XGBoost)was then used to perform analysis on the feature data to achieve damage detection with high accuracy and high performance.The proposed method was applied in a numerical simulation study on a three-span continuous girder and further validated experimentally on a scaled model of a cable-stayed bridge.The numerical simulation results show that the identification errors remain within 2.9%for six single-damage cases and within 3.1%for four double-damage cases.The experimental validation results demonstrate that when the tension in a single cable of the cable-stayed bridge decreases by 20%,the method accurately identifies damage at different cable locations using only sensors installed on the main girder,achieving identification accuracies above 95.8%in all cases.The proposed method shows high identification accuracy and generalization ability across various damage scenarios.
文摘Aim To obtain an optimizing range of the main configuration parameters of double swirls combustion system (DSCS) Methods To analyze the influence of DS combustion cham-ber configuration parameters on fuel spray and mixing by means of the fuel jet developmentperiphery charts obtained by the high speed photography with a modeling test device deve-loped by authors,and to examine it by the tests on a single cylinder diesel engine.Resultsand Conclusion The mixing process can be divided into four phases.The optimizing range of the ration of the inner chamber diameter to the cylinder bore,d2/D,is 0.4-0.7; and the outerchamber diameter,d1 the height of the circular ridge to the piston top face,h1,the radius of outer/inner chamber circle,R1,R2 ,the max depth of outer/inner chamber bowl,H1,H2,etc. are also important
文摘The finding of the compound structure of a new four-scrolls chaotic system is reported, which is obtained by merging together two symmetrical attractors. And the two symmetrical attractors are generated only by adding a constant gain to the original system. Also, the forming procedure of the new four-scrolls chaotic attractor is explored and the relation between the constant gain and the properties of the system is given.
文摘The molecular structure of a higher plant myosin with two 174 kD heavy chains purified from the tendrils of Luffa cylindrica (L.) Roem. was viewed by electron microscopy. The myosin exhibited actin_activated MgATPase activity and could be recognized immunologically by a monoclonal antibody against the skeletal muscle myosin. Electron micrographs of rotary shadowed images of this protein revealed that it had two heads with size and shape similar to those of the skeletal muscle myosin and a relatively short tail in comparison with the conventional myosin. Luffa tendril actin filaments were also visualized and occasionally other Luffa myosin_like proteins with globular structure at the tail ends were also observed. The structural similarity and immunological cross reactivity with antibodies against muscle myosin demonstrate that the 174 kD Luffa tendril myosin is a double_headed myosin. The possible involvement of myosin_actin interactions in Luffa tendril contact coiling will be the subject of further research.
文摘The experiment was performed to evaluate the progenies of plant lines transgenic for auxin synthesis genes derived from Ri T-DNA. Four lines of the transgenic plants were selfcrossed and the foreign auxin genes in plants of T5 generation were confirmed by Southern hybridization. Two lines, D1232 and D1653, showed earlier folding of expanding leaves than untransformed line and therefore had early initiation of leaf y head. Leaf cuttings derived from plant of transgenic line D1653 produced more adventitious roots than the control whereas the cuttings from folding leaves had much more roots than rosette leaves at folding stage, and the cuttings from head leaves had more roots than rosette leaves at heading stage. It is demonstrated that early folding of transgenic leaf may be caused by the relatively higher concentration of auxin. These plant lines with auxin transgenes can be used for the study of hormonal regulation in differentiation and development of plant organs nd for the breeding of new varietywith rapid growth trait.
文摘Flat Steel Ribbon Wound Pressure Vessels (FSRWPVs) are used in many important industry areas. There is no such kind of pressure vessel exploding on operation for its reasonable structure design. Many explosion experiments on Flat Steel Ribbon Wound Pressure Vessel showed that their limited load pressure is related to the winding angle of the steel ribbons. FSRWPVs with reasonable winding angle have better security and lower cost. Reasonable angels given at the end of this paper facilitate engineering design.
基金National Natural Science Foundation of China(No.61806006)Jiangsu University Superior Discipline Construction Project。
文摘In view of the problems of multi-scale changes of segmentation targets,noise interference,rough segmentation results and slow training process faced by medical image semantic segmentation,a multi-scale residual aggregation U-shaped attention network structure of MAAUNet(MultiRes aggregation attention UNet)is proposed based on MultiResUNet.Firstly,aggregate connection is introduced from the original feature aggregation at the same level.Skip connection is redesigned to aggregate features of different semantic scales at the decoder subnet,and the problem of semantic gaps is further solved that may exist between skip connections.Secondly,after the multi-scale convolution module,a convolution block attention module is added to focus and integrate features in the two attention directions of channel and space to adaptively optimize the intermediate feature map.Finally,the original convolution block is improved.The convolution channels are expanded with a series convolution structure to complement each other and extract richer spatial features.Residual connections are retained and the convolution block is turned into a multi-channel convolution block.The model is made to extract multi-scale spatial features.The experimental results show that MAAUNet has strong competitiveness in challenging datasets,and shows good segmentation performance and stability in dealing with multi-scale input and noise interference.
文摘The present work aimed to investigate the effect of coiling process conditions on microstructure development in a low-Si content TRIP (transformation-induced plasticity)-assisted steel after thermomechanical processing. In this framework, compression samples which were deformed above Tnr and then intercritically annealed were held isothermally for different durations at temperatures below bainite transformation start temperature. Microstructure of samples were characterized by optical and electron microscopy, XRD (X-ray diffraction) and M6ssbauer spectroscopy. The results indicated that due to low-silicon content of the present steel, the incomplete bainite reaction phenomena was not observed and, hence, the maximum carbon enrichment of residual austenite was achieved in the samples which held for short durations. It was also shown that the maximum carbon enrichment and volume fraction of residual austenite were achieved at intermediate bainite hold temperature of 450 ℃ as the result of competing phenomena, such as microstructural refinement, dislocation density, carbide precipitation and growth.
文摘AIM:To study the epidemiologic indicators of uptake and characteristic colonoscopic findings in the Croatian National Colorectal Cancer Screening Program.METHODS:Colorectal cancer(CRC) was the second leading cause of cancer mortality in men(n = 1063,49.77/100 000),as well as women(n = 803,34.89/100 000) in Croatia in 2009.The Croatian National CRC Screening Program was established by the Ministry of Health and Social Welfare,and its implementation started in September,2007.The coordinators were recruited in each county institute of public health with an obligation to provide fecal occult blood testing(FOBT) to the participants,followed by colonoscopy in all positive cases.The FOBT was performed by hypersensitive guaiac-based Hemognost card test(Biognost,Zagreb).The test and short questionnaire were delivered to the home addresses of all citizens aged 50-74 years consecutively during a 3-year period.Each participant was required to complete the questionnaire and send it together with the stool specimen on three test cards back to the institute for further analysis.About 4% FOBT positive cases are expected in normal risk populations.A descriptive analysis was performed.RESULTS:A total of 1 056 694 individuals(born between 1933-1945 and 1952-1957) were invited to screening by the end of September 2011.In total,210 239(19.9%) persons returned the envelope with a completed questionnaire,and 181 102 of them returned it with a correctly placed stool specimen on FOBT cards.Until now,12 477(6.9%),FOBT-positive patients have been found,which is at the upper limit of the expected values in European Guidelines for Quality Assurance in CRC Screening and Diagnosis [European Union(EU) Guidelines].Colonoscopy was performed in 8541 cases(uptake 66%).Screening has identified CRC in 472 patients(5.5% of colonoscopied,3.8% of FOBT-positive,and 0.26% of all screened individuals).This is also in the expected range according to EU Guidelines.Polyps were found and removed in 3329(39% of colonoscopied) patients.The largest number of polyps were found in the left half of the colon:64%(19%,37% and 8% in the rectum,sigma,and descendens,respectively).The other 36% were detected in the proximal part(17% in the transverse colon and 19% in ceco-ascending colon).Small polyps in the rectum(5-10 mm in diameter),sigmoid and descending colon were histologically found to be tubular adenomas in 60% of cases,with a low degree of dysplasia,and 40% were classified as hyperplastic.Polyps of this size in the transverse or ceco-ascending colon in almost 20% had a histologically villous component,but still had a low degree of dysplasia.Polyps sized 10-20 mm in diameter were in 43% cases tubulovillous,and among them,32% had areas with a high degree of dysplasia,especially those polyps in the cecoascending or transverse part.The characteristics of the Croatian CRC Screening National Program in the first 3 years were as follows:relatively low percentage of returned FOBT,higher number of FOBT-positive persons but still in the range for population-based programs,and higher number of pathologic findings(polyps and cancers).CONCLUSION:These results suggest a need for intervention strategies that include organizational changes and educational activities to improve awareness of CRC screening usefulness and increase participation rates.
文摘This study aims at investigating the effects of the pre-task planning mode on listening comprehension of Chinese EFL (English as a foreign language) learners as well as students' opinions towards the pre-task planning mode Three step~., namely, concept mapping, strategic planning, as well as rehearsal, are employed in the pre-task planning mode in the present study. There are altogether 40 second-year English majors participated in the present study, and they are randomly assigned into the experimental group and the control group. The instruments employed in the present study to achieve the research purposes include the listening comprehension test, the teacher's log, the students' opinion questionnaires, the students' open-ended questionnaires, and the semi-structured interviews. Research findings revealed that there were significant main effects on the listening comprehen,;ion of Chinese EFL learners after the training by the pre-task planning mode. Moreover, the students held positive attitudes towards the pre-task planning mode
文摘Objective: The aim of this study was to analyze factors of psychological disorder experienced by 98 cancer patients and to probe into intervention measures in accordance with the corresponding bad psychological factors. Methods: A questionnaire survey was conducted in the test group (n = 98) by filling out a symptom checklist 90 (SCL-90). And then the survey result was compared with the normal group (n = 1388) contained in relevant references. Results: Except for hostile factor that was similar to normal level (P 〉 0.05), other 8 factors were higher than in normal group (P 〈 0.01). And the cancer patients were classified with the survey results. Conclusion: Compared with normal persons, cancer patients have more psychological problems and related intervention measures are sought necessarily to improve the quality of life, to advance the immune function and to prolong the survival time of patients.
文摘AIM: TO investigate the role of Lactobacillus crispatus (L. crispatus) strain China Center for Type Culture Col- lection (CCTCC) M206119 in intestinal inflammation.METHODS: Forty 8-wk-old Balb/c mice (20± 2 g) were divided into four groups of 10 mice each. Three groups that had received dextran sulfate sodium (DSS) were administered normal saline, sulfasalazine or CCTCC M206119 strain, and the fourth group received none of these. We assessed the severity of colitis using a disease activity index, measured the colon length and weight, collected stools and mesenteric lymph nodes for bacterial microflora analysis. One centimeter of the proximal colon, middle colon and distal colon were collected and fixed in 10% buffered formalin, dehydrated in ethanol, and embedded in paraffin. Interleukin (IL)- 1β, IL-6 and tumor necrosis factor (TNF)-α expression was detected using reverse transcription polymerase chain reaction. Protective factors zonula occludens (ZO)-1 and β-defensin 2 were detected by immunoblot-ting. The features of CCTCC M206119 strain were identified based on morphology, biochemical profile, and 16S RNA sequencing.RESULTS: DSS-colitis animals treated with CCTCC M206119 had markedly more severe disease, with greater weight loss, diarrhea, fecal bleeding, and shortened colon length. In addition, the CCTCC-M206119- treated group had comparatively higher histologi- cal scores and more neutrophil infiltration than the controls. Expression of protective factors ZO-1 and β-defensin 2 was downregulated due to destruction of the mucosal barrier after CCTCC M206119 strain treatment. An in vitro assay demonstrated that CCTCC M206119 strain increased the nuclear translocation of nuclear factor-κB in epithelial cells. Intestinal proinflam- matory or anti-inflammatory cytokine responses were evaluated. Proinflammatory colonic cytokine (IL-Iβ, IL-6 and TNF-α) levels were clearly increased in CCTCC- M206119-treated animals, whereas anti-inflammatory colonic cytokine (IL-10) level was lowered compared with saline or 5-aminosalicylic-acid-treated DSS-colitis mice. Next, CCTCC M206119 strain was characterized as 1. crispatus by microscopic morphology, biochemical tests and 16S rRNA gene level.CONCLUSION: Not all lactobacilli are beneficial for in- testinal inflammation, and L. crispatus CCTCC M206119 strain is involved in exacerbation of intestinal inflamma- tion in DSS-colitis mice.
文摘This study attempts to examine the conceptual and political bases of Bangsamoro women's participation on politics in terms of electoral, policy-making, and peace processes in Lanao del Sur. The descriptive correlation method was used, which utilized a survey questionnaire as the primary source in acquiring the data. The findings showed that the majority of the respondents were young, most of them were married and had finished elementary degree. It was observed that their participation in electoral, policy-making, and peace processes was high but vote buying, political ideology, and corruption were considered to be their problems. Despite cultural barriers, a clear understanding of their role as Muslim woman can increase their participation. Hence, total reform in the government as well as the Barangay should be done including their participation for the training programs on leadership, accountability and transparency, human and political rights awareness as well as the Shariah Law and the Philippine Constitution. Political party system that has a strong alliance to other political parties shall also be established in order to assure their participation. Linkages to other civil society like class-based organizations, occupation-based associations, and interest-based societies shall be tapped by the leaders of Bangsamoro women.
文摘Acquisition of speaking Turkish students since skills is among the most essential language skills for students currently, especially among language competency is measured through speaking. Every language learner desires to acquire correct communicative skills and fluency in speaking, while teachers aim to give the necessary education in speaking, as well. This study reveals the essence of acquiring speaking competency for learners, and how important it is to teach speaking skills with correct methods and methodology. With the questionnaire analysis on Turkish students and teachers at a Turkish university, the theoretical knowledge on "essence" is blended with the questionnaire results provided from students and teachers in order to emphasize the necessity and reach more practical solutions for the current need of learning and teaching speaking.
文摘Despite the presence of bye-laws, solid waste management continues to be an issue in Mbarara municipality with households and businesses continuing to dump solid waste on open plots, low-lying areas, public spaces and rivers, or simply burning it in their backyards. This qualitative study aimed at establishing reasons as to why there was still improper solid waste management in Mbarara municipality and also establishing its constraints. Tools used included semi-structured questionnaires, observation and photographs. Two hundred and ninety-four participants (24 solid waste collectors, eight municipal council members and 262 community members) participated in the study. The study revealed both insufficient budget (87.5%) and insufficient equipment (50%) as the most common policy challenges in implementing proper solid waste management. Solid waste collectors not being comfortable with their salaries (79.2%), limited sensitization regarding solid waste management (66%) and limited necessary tools (58.3%) as other challenges faced by solid waste management policy makers and implementers and finally, community members having limited awareness about laws governing solid waste management (61.1%). In conclusion, insufficient budget, insufficient equipment, poor motivation and inadequate sensitization were found to be the major reasons as to why there was still improper solid waste management in Mbarara municipality, western Uganda.