Akebia is a wild fruit originating in the Yangtse river valley and the surrounding areas. It includes mainly three species (subspecies): Akebia trifoliata, Akebia trifoliata subsp, australis, and Akebia quinata. It...Akebia is a wild fruit originating in the Yangtse river valley and the surrounding areas. It includes mainly three species (subspecies): Akebia trifoliata, Akebia trifoliata subsp, australis, and Akebia quinata. It has many good traits, such as large fruit size, early fruit-setting and high yield, excellent eating quality, and good environmental adaptability. However, there are some shortcomings with the fruit, including thick skin, excessive number of seeds, and relatively small proportion of edible flesh. Akebia is also a traditional Chinese medicine, which has the functions of relieving internal heat and diuresis, dredging venation and improving blood circulation, cleansing facial chloasma, detoxication and anti-cancer activities. Akebia can be used as fresh fruit, for processing, and for pharmaceutical purposes. We have been undertaking a series of research on the domestication and utilization of Akebia, including cultivar selection, techniques for cultivation, storage and processing, and related basic studies. A Chinese trade name “Hehuanguo” and an English trade name “Joyfruit” have been registered for Akebia to facilitate its commercial development.展开更多
Potential causes of abnormal liver function tests include viral hepatitis,alcohol intake,nonalcoholic fatty liver disease,autoimmune liver diseases,hereditary diseases,hepatobiliary malignancies or infection,gallstone...Potential causes of abnormal liver function tests include viral hepatitis,alcohol intake,nonalcoholic fatty liver disease,autoimmune liver diseases,hereditary diseases,hepatobiliary malignancies or infection,gallstones and drug-induced liver injury.Moreover,the liver may be involved in systemic diseases that mainly affect other organs.Therefore,in patients without etiology of liver injury by screening serology and diagnostic imaging,but who have systemic diseases,the abnormal liver function test results might be caused by the systemic disease.In most of these patients,the systemic disease should be treated primarily.However,some patients with systemic disease and severe liver injury or fulminant hepatic failure require intensive treatments of the liver.展开更多
The diversity and distribution patterns of soil nematode communities in phaeozem agroecosystems of Northeast China were assessed to evaluate nematode taxonomic diversity and functional diversity in relation to climati...The diversity and distribution patterns of soil nematode communities in phaeozem agroecosystems of Northeast China were assessed to evaluate nematode taxonomic diversity and functional diversity in relation to climatic condition and soil characteristics in human modified landscape. Along the latitudinal gradient, soil samples were collected from north (Hailun) to south (Gongzhuling) down to a depth of 100 cm with intervals of 030, 20-40, 40-60, 60-80, and 80-100 cm. The nematode abundance and taxonomic diversity (generic richness) were lower at Hailun than at other sites, and higher values of evenness were observed at Hailun and Harbin than at Dehui and Gongzhuling. Nematode faunal analysis revealed that soil food web at Hailun was sueeessionally more mature or structured, and the environment little disturbed, while at Harbin and Gongzhuling, the soil food web was degraded with stressed environment. The environmental variables relevant in explaining the patterns of nematode distribution and diversity in phaeozem agroecosystems, using canonical correspondence analysis (CCA), were the mean annual temperature, total nitrogen, electrical conductivity, mean annual precipitation, and other soil properties. Among these variables, the mean annual temperature was a relatively important factor, which could explain 29.05% of the variations in nematode composition.展开更多
Protected areas(PAs) have experienced explosive growth in Northwest China over the last three decades, but their effectiveness in representing regional ecological system diversity has not attracted considerable attent...Protected areas(PAs) have experienced explosive growth in Northwest China over the last three decades, but their effectiveness in representing regional ecological system diversity has not attracted considerable attention. Low effectiveness would exacerbate the conservation-development conflicts, particularly those that arise as a result of the Great Western Development Strategy(GWDS). Thus, an assessment of the effectiveness of the PA network has become quite important. We proposed natural vegetation communities to represent regional ecological system diversities, and proposed Global 200 Priority Ecoregions, Important Bird Areas, and ecosystem function regions to represent important conservation areas. To determine their effectiveness, we studied the extent to which ecological system diversities and important conservation areas are represented by the existing 96 PAs. Our results indicated that the total coverage of vegetation communities in PAs in Northwest China is not sufficiently comprehensive. As the PA system has expanded, the growth in the total area of the PAs has been greater than that of their vegetation community richness. While most of the important conservation areas are covered by PAs, some regions have not yet reached the 10% threshold; further, PAs are distributed unevenly and conservation gaps remain in the region. Therefore, these regions should receive more attention when planning new PAs. It is vital that more biodiversity datasets and assessment of ecosystem function regions are integrated in order to provide a basis for the government to formulate appropriate protection and development strategies.展开更多
Objective:To study the effect of Simvastatin on the left ventricular mass and endothelial function and to investigate the relationship between their changes in the patients with essential hypertension(EH). Methods: 5...Objective:To study the effect of Simvastatin on the left ventricular mass and endothelial function and to investigate the relationship between their changes in the patients with essential hypertension(EH). Methods: 50 patients with hypertension without severe complication were divided into two groups in a randomized,controlled and single blind trial.Group I(n=25)were given Simvastatin and hydragogue for 12 weeks while Group Ⅱ were given hydragogue during the same time.We detected the left ventricular mass and the brachial artery dilatation induced by reactive hyperemia(DIRH)or nitroglycerin(DING)respectively with ultrasonography in all patients before and after treatment.25 normal subjects without any treatment were taken as the control. Results:The left ventricular mass index(LVMI)was higher in the two groups of patients[(133.61±31.02)g/m 2;(118.04±39.62)g/m 2]than that in the control(88.79±22.73)g/m 2 before treatment(P<0.01,0.000 1,respectively)while the blood pressure was higher.The DIRH was lower in the two groups of patients(5.93±2.24)%;(6.54±3.16)%than that in the control(13.09±2.99)%,P<0.000 1.There was no significantly differences in age,serum concentrations of total cholesterol,triglyceride,sugar,blood pressure or the DING between two groups of patients and the control(P>0.05).And there was no significant difference in the all variables between group Ⅰ and group Ⅱ before treatment.After treatment the LVMI decreased[(133.61±31.02)g/m 2 VS(91.07±16.01)g/m 2,P<0.01]and the DTRH increased[(5.93±2.24)% VS(13.53±2.38)%,P<0.01]in the patients of group Ⅰ while there was no significant change in LVMI and DIRH in the patients of group Ⅱ.The blood pressure in the two groups of patients was decreased to the normal.Compared with group Ⅱ,the changes of LVMI and DIRH was higher in patients of group Ⅰ though the serum concentrations of total cholesterol,triglyceride or sugar were not significantly different.No significant change in serum concentrations oftotal cholesterol,triglyceride or sugar was found during treatment in the two groups of patients.Analysis showed that the LVMI correlated with DIRH and the change of LVMI correlated better with the change of DIRH(r=-0.56;0.69,P<0.000 1,respectly). Conclusions: The increase of left ventricular mass was related with endothelial dysfunction in essential hypertension.Being independent of the changes of serum concentrations of total cholesterol,triglyceride or sugar and blood pressure,Simvastatin could inhibit the increase of left ventricular mass and improve endothelial function.展开更多
Objective: To investigate the immunological function of a yeast expression system for thymosin α1 (Tα1). Methods: A constructed Tetl yeast expression system was used to investigate the immunological function of ...Objective: To investigate the immunological function of a yeast expression system for thymosin α1 (Tα1). Methods: A constructed Tetl yeast expression system was used to investigate the immunological function of orally administered Tα1. Dried yeast containing three different concentration of Tα1 was fed to normal Balb/c mice and other Balb/c mice whose immunities were inhibited in advance by cyclophosphamide. Synthesized Tα1 peptide was used as positive control and dried yeast with empty plasmid was used as negative control. CD4^+ and CD8^+ levels were detected by flow cytometry assay. TNF-α, IFN-γ, IL-2, IL-6 and IL-10 levels were detected by liquid chip. Results: In normal Balb/c mice or immune inhibition Balb/c mice, CD8^+ levels were significantly increased. Especially in immune inhibition Balb/c mice, CD8^+ levels in synthesized Tα1 group (18.77%±4.72%), small dose group (13.48%±6.17%) and large dose group (22.74%±1.09%) were significantly higher than that in empty yeast control group (7.49%±2.14%). Conclusion: Orally administered Tα1 has its certain immunomodulatory function.展开更多
Signcryption, which was introduced by ZHEN~ is a cryptographic primitive that fulfils the functions of both digital signature and encryption and guarantees confidentiality, integrity and non-repudiation in a more effi...Signcryption, which was introduced by ZHEN~ is a cryptographic primitive that fulfils the functions of both digital signature and encryption and guarantees confidentiality, integrity and non-repudiation in a more effi- cient way. Certificateless signcryption and pro- xy signcryption in identity-based cryptography were proposed for different applications. Most of these schemes are constructed by bilinear pairings from elliptic curves. However, some schemes were recently presented without pai- rings. In this paper, we present a certificateless proxy identity-based signcryption scheme with- out bilinear pairings, which is efficient and secure.展开更多
Among 180 patients with female urethral syndrome, 128 were treated by acupuncture and moxibustion and 52 by western medicine as controls. The short-term effective rate in the acupuncture and moxibustion group was 90.6...Among 180 patients with female urethral syndrome, 128 were treated by acupuncture and moxibustion and 52 by western medicine as controls. The short-term effective rate in the acupuncture and moxibustion group was 90.6% and the long-term effective rate, 80.4%; whereas the short-term effective rate of the control group was 26.9% (P 0.05). Sixty-nine cases from the acupuncture and moxibustion group and 39 from the control group were subjected before and after treatment to determinations of the maximal bladder pressure, maximal abdominal pressure, bladder-neck pressure, and maximal urethral closure pressure during urination. All these indexes were decreased remarkably in the acupuncture and moxibustion group, while no changes were observed in the control group.展开更多
OBJECTIVE To evaluate the effect and safety of a Molecular Adsorbent Recycling System (MARS) in treating posthepatoectomy hepatic failure (AHF) patients surgically treated for primary hepatocellular carcinoma (HC...OBJECTIVE To evaluate the effect and safety of a Molecular Adsorbent Recycling System (MARS) in treating posthepatoectomy hepatic failure (AHF) patients surgically treated for primary hepatocellular carcinoma (HCC). METHODS 12 AHF patients induced by resection of HCC were treated with MARS before orthotopic liver transplantation (OLT). Their vital signs, urine volume, APACHElll and Glasgow scores were monitored. Routine laboratory blood tests, measurements of coagulatory function, liver and kidney function, serum ammonia, lactic acid and blood gas were conducted before and after treatment with MARS. All of the patients were followed up for a period of 6 months after OLT for prognosis and complication assessment. RESULTS Each patient was treated with MARS for 2-5 times (average of 3.6) with a length of 8-24 h each time. Their mean arterial blood pressure and urine volume were improved, APACHE III and Glasgow scores were better. Liver function was improved with the following alterations before and after treatment with MARS: serum ammonia (127.1±21.4 umol/L vs. 77.4±19.7 umol/L, P〈0.05), lactic acid (6.53±0.45 mmol/L vs. 3.75± 0.40 mmol/L, P〈0.05) and total bilirubin (452.3±153.7 umol/L vs. 230.9± 115.2 umol/L, P〈0.05). However, there was no significant change in platelet count (44.25±3.60×10^9/L vs. 43.19±8.26×10^9/L, P〉0.05) on international normalized ratio (INR) (2.74±0.50 vs. 2.82±0.60, P〉0.05), which showed the safety of MARS. For all patients no serious adverse effects occurred during the treatment with MARS. CONCLUSION MARS is effective and safe for treatment of AHF patients with HCC, especially as a bridge to OLT when a donor organ is not available.展开更多
Anemia is the most common complication of inflammatory bowel disease (IBD). Control and inadequate treatment leads to a worse quality of life and increased morbidity and hospitalization. Blood loss, and to a lesser ex...Anemia is the most common complication of inflammatory bowel disease (IBD). Control and inadequate treatment leads to a worse quality of life and increased morbidity and hospitalization. Blood loss, and to a lesser extent, malabsorption of iron are the main causes of iron def iciency in IBD. There is also a variable component of anemia related to chronic inflammation. The anemia of chronic renal failure has been treated for many years with recombinant human erythropoietin (rHuEPO), which significantly improves quality of life and survival. Subsequently, rHuEPO has been used progressively in other conditions that occur with anemia of chronic processes such as cancer, rheumatoid arthritis or IBD, and anemia associated with the treatment of hepatitis C virus. Erythropoietic agents complete the range of available therapeutic options for treatment of anemia associated with IBD, which begins by treating the basis of the inflammatory disease, along with intravenous iron therapy as f irst choice. In cases of resistance to treatment with iron, combined therapy with erythropoietic agents aims to achieve near-normal levels of hemoglobin/hematocrit (11-12 g/dL). New formulations of intravenous iron (iron carboxymaltose) and the new generation of erythropoietic agents (darbepoetin and continuous erythropoietin receptor activator) will allow better dosing with the same eff icacy and safety.展开更多
With the rapid development of Internet of Things (IoT),the issue of trust in distributed routing systems has attracted more research attention.The existing trust management frameworks,however,suffer from some possible...With the rapid development of Internet of Things (IoT),the issue of trust in distributed routing systems has attracted more research attention.The existing trust management frameworks,however,suffer from some possible attacks in hostile environments,such as false accusation,collusion,on-off,and conflicting behavior.Therefore,more comprehensive models should be proposed to predict the trust level of nodes on potential routes more precisely,and to defeat several kinds of possible attacks.This paper makes an attempt to design an attack-resistant trust management model based on beta function for distributed routing strategy in IoT.Our model can evaluate and propagate reputation in distributed routing systems.We first describe possible attacks on existing systems.Our model is then proposed to establish reliable trust relations between self-organized nodes and defeat possible attacks in distributed routing systems.We also propose a theoretical basis and skeleton of our model.Finally,some performance evaluations and security analyses are provided to show the effectiveness and robustness of our model compared with the existing systems.展开更多
Kenneth Burke's rhetoric on language as a symbolic action offers an enlightening perspective for revealing the connection between the motivations and actions of the characters in Thomas Kyd's The Spanish Tragedy. Th...Kenneth Burke's rhetoric on language as a symbolic action offers an enlightening perspective for revealing the connection between the motivations and actions of the characters in Thomas Kyd's The Spanish Tragedy. This work is a Renaissance drama that features hues of rhetorical language. Linguistic obfuscation, scapegoat mechanism, and the malfunction and dysfunction of language in victimization and revenge are thrown into relief through Burke's elaborate system of the symbolism of language. Analyzing the discursive performances of the main characters, readers could get clues of their motives that drive their actions, which are both a representation and an illustration of how language as a symbolic action works in literature展开更多
This paper presents an architecture of a hybrid recommender system in E-commerce environment. The goal of the system is to make special improvements in giving precisely personalized recommendation through some effecti...This paper presents an architecture of a hybrid recommender system in E-commerce environment. The goal of the system is to make special improvements in giving precisely personalized recommendation through some effective measures. Based on the study on the existing recommendation methods of both the conventional similarity function and the conventional feedback function, several improvement algorithms are developed to enhance the precision of recommendation, which include three improved similarity functions, four improved feedback functions, and adoption of both explicit and implicit preferences in individual user profile. Among them, issues and countermeasures of a new user, prominent preferences and long-term preferences are nicely addressed to gain better recommendation. The users preferences is so designed to be precisely captured by a user-side agent, and can make self-adjustment with explicit or implicit feedback.展开更多
Abstract: This paper focuses on the first-or- der and second-order performance of dual-hop underlay cognitive radio systems with oppor- tunistic relaying (UCR-OR) over indepen- dent and non-identically distributed ...Abstract: This paper focuses on the first-or- der and second-order performance of dual-hop underlay cognitive radio systems with oppor- tunistic relaying (UCR-OR) over indepen- dent and non-identically distributed (i.ni.d) Rayleigh fading channels. For the UCR-OR systems, the tolerable maximum interference power (TMIP) Q at primary users (PUs) and the allowable maximum transmission power limit (AMTP) P at secondary users (SUs) are considered, simultaneously. We first obtain the closed-form solutions to the first-order performance such as outage probability, ave- rage symbol error ratio (SER), and ergodic capacity (EC). Secondly, we investigate the second-order statistical performance, i.e., ave- rage outage rate (AOR) and average outage duration (AOD). With the consideration that in practice implementation the receiver perfor- mance is primarily influenced by the signal- to-noise ratio (SNR) (not the signal envelope), the second-order statistical performance is investigated based on the equivalent instan- taneous end-to-end SNR. Finally, we present the detailed performance comparison analysis of UCR-OR systems by defining a random variable ,μ=Pmax/Q. The results show that the effect of μ on the first-order and second-or- der performances is different greatly. For the first-order performance, the perlbrmance gap is negligible when the value of// is relatively large. However, for the second-order one, the gap is distinct.展开更多
The fast excitation system of a composite magnetic controllable reactor is introduced. In this excitation system, a bidirectional function (i.e. fast forward excitation and backward forcible demagnetization) is avai...The fast excitation system of a composite magnetic controllable reactor is introduced. In this excitation system, a bidirectional function (i.e. fast forward excitation and backward forcible demagnetization) is available, which can significantly improve the response speed, performances, and application scope of magnetic controllable reactor.展开更多
Gait recognition is the key question of functional electrical stimulation (FES) system control for paraplegic walking. A new risk-tendency-graph (RTG) method was proposed to recognize the stability information in FES-...Gait recognition is the key question of functional electrical stimulation (FES) system control for paraplegic walking. A new risk-tendency-graph (RTG) method was proposed to recognize the stability information in FES-assisted walking gait. The main instrument was a specialized walker dynamometer system based on a multi-channel strain-gauge bridge network fixed on the walker frame. During walking process, this system collected the reaction forces between patient's upper extremities and walker and converted them into RTG morphologic curves of dynamic gait stability in temporal and spatial domains. To demonstrate the potential usefulness of RTG, preliminary clinical trials were done with paraplegic patients. The gait stability levels of two walking cases with 4- and 12-week FES training from one subject were quantified (0.43 and 0.19) from the results of temporal and spatial RTG. Relevant instable phases in gait cycle and dangerous inclinations of patient's body during walking process were also brought forward. In conclusion, the new RTG method is practical for distinguishing more useful gait stability information for FES system control.展开更多
Objective To assess the sensitivity of high-resolution CT (HRCT) in detecting pulmonary involvement attributed to systemic lupus erythematosus (SLE). Methods Plain chest radiography, HRCT, and pulmonary function testi...Objective To assess the sensitivity of high-resolution CT (HRCT) in detecting pulmonary involvement attributed to systemic lupus erythematosus (SLE). Methods Plain chest radiography, HRCT, and pulmonary function testing of 36 patients with SLE were analyzed. Results The sensitivity of the pulmonary involvement by HRCT, plain chest radiography and pulmonary function testing were 88.9%,36.1%,and 33.3%, respectively. Conclusion HRCT played an important role in detecting pulmonary involvemen due to SLE, especially in early and mild cases.展开更多
In order to improve the accuracy of English teaching quality evaluation, so as to promote the quality of English teaching, an evaluation method of English teaching quality is proposed based on fuzzy comprehensive eval...In order to improve the accuracy of English teaching quality evaluation, so as to promote the quality of English teaching, an evaluation method of English teaching quality is proposed based on fuzzy comprehensive evaluation, the index system model of English teaching quality evaluation is constructed, a decision tree model is used for construction of English teaching quality index model, objective function of English teaching quality evaluation is constructed based on fuzzy decision model, the conjugate function analysis method is used to optimize the decision function, the attributes that can reflect the quality of English Teaching is extracted, accurate evaluation and prediction of English teaching quality are realized. The simulation results show that the method of English teaching quality evaluation is reliable, it has high degree of confidence, evaluation result is accurate.展开更多
The performance of the power assist, global optimization solved by dynamic programming (DP) method, Chery and Insight control strategies are analyzed using the mild parallel hybrid electric vehicle (PHEV) model ba...The performance of the power assist, global optimization solved by dynamic programming (DP) method, Chery and Insight control strategies are analyzed using the mild parallel hybrid electric vehicle (PHEV) model based on Insight structure. The influence of the four control strategies to the load power of the electric motor system used on parallel hybrid electric vehicle is studied. It is found that 80 percent of the motor load power points are under 1/5 of the electric peak power. The motor load power of the power assist control strategy is distributed in the widest range during generating operation, and the motor load power of the global optimization control strategy has the smallest one.展开更多
文摘Akebia is a wild fruit originating in the Yangtse river valley and the surrounding areas. It includes mainly three species (subspecies): Akebia trifoliata, Akebia trifoliata subsp, australis, and Akebia quinata. It has many good traits, such as large fruit size, early fruit-setting and high yield, excellent eating quality, and good environmental adaptability. However, there are some shortcomings with the fruit, including thick skin, excessive number of seeds, and relatively small proportion of edible flesh. Akebia is also a traditional Chinese medicine, which has the functions of relieving internal heat and diuresis, dredging venation and improving blood circulation, cleansing facial chloasma, detoxication and anti-cancer activities. Akebia can be used as fresh fruit, for processing, and for pharmaceutical purposes. We have been undertaking a series of research on the domestication and utilization of Akebia, including cultivar selection, techniques for cultivation, storage and processing, and related basic studies. A Chinese trade name “Hehuanguo” and an English trade name “Joyfruit” have been registered for Akebia to facilitate its commercial development.
文摘Potential causes of abnormal liver function tests include viral hepatitis,alcohol intake,nonalcoholic fatty liver disease,autoimmune liver diseases,hereditary diseases,hepatobiliary malignancies or infection,gallstones and drug-induced liver injury.Moreover,the liver may be involved in systemic diseases that mainly affect other organs.Therefore,in patients without etiology of liver injury by screening serology and diagnostic imaging,but who have systemic diseases,the abnormal liver function test results might be caused by the systemic disease.In most of these patients,the systemic disease should be treated primarily.However,some patients with systemic disease and severe liver injury or fulminant hepatic failure require intensive treatments of the liver.
基金supported by the National Key Basic Research Support Foundation of China (No.2005CB121105)the National Natural Science Foundation of China (No.30670379)
文摘The diversity and distribution patterns of soil nematode communities in phaeozem agroecosystems of Northeast China were assessed to evaluate nematode taxonomic diversity and functional diversity in relation to climatic condition and soil characteristics in human modified landscape. Along the latitudinal gradient, soil samples were collected from north (Hailun) to south (Gongzhuling) down to a depth of 100 cm with intervals of 030, 20-40, 40-60, 60-80, and 80-100 cm. The nematode abundance and taxonomic diversity (generic richness) were lower at Hailun than at other sites, and higher values of evenness were observed at Hailun and Harbin than at Dehui and Gongzhuling. Nematode faunal analysis revealed that soil food web at Hailun was sueeessionally more mature or structured, and the environment little disturbed, while at Harbin and Gongzhuling, the soil food web was degraded with stressed environment. The environmental variables relevant in explaining the patterns of nematode distribution and diversity in phaeozem agroecosystems, using canonical correspondence analysis (CCA), were the mean annual temperature, total nitrogen, electrical conductivity, mean annual precipitation, and other soil properties. Among these variables, the mean annual temperature was a relatively important factor, which could explain 29.05% of the variations in nematode composition.
基金Under the auspices of National Science&Technology Pillar Program During the Twelfth Five-year Plan Period(No.2011BAC09B08)
文摘Protected areas(PAs) have experienced explosive growth in Northwest China over the last three decades, but their effectiveness in representing regional ecological system diversity has not attracted considerable attention. Low effectiveness would exacerbate the conservation-development conflicts, particularly those that arise as a result of the Great Western Development Strategy(GWDS). Thus, an assessment of the effectiveness of the PA network has become quite important. We proposed natural vegetation communities to represent regional ecological system diversities, and proposed Global 200 Priority Ecoregions, Important Bird Areas, and ecosystem function regions to represent important conservation areas. To determine their effectiveness, we studied the extent to which ecological system diversities and important conservation areas are represented by the existing 96 PAs. Our results indicated that the total coverage of vegetation communities in PAs in Northwest China is not sufficiently comprehensive. As the PA system has expanded, the growth in the total area of the PAs has been greater than that of their vegetation community richness. While most of the important conservation areas are covered by PAs, some regions have not yet reached the 10% threshold; further, PAs are distributed unevenly and conservation gaps remain in the region. Therefore, these regions should receive more attention when planning new PAs. It is vital that more biodiversity datasets and assessment of ecosystem function regions are integrated in order to provide a basis for the government to formulate appropriate protection and development strategies.
文摘Objective:To study the effect of Simvastatin on the left ventricular mass and endothelial function and to investigate the relationship between their changes in the patients with essential hypertension(EH). Methods: 50 patients with hypertension without severe complication were divided into two groups in a randomized,controlled and single blind trial.Group I(n=25)were given Simvastatin and hydragogue for 12 weeks while Group Ⅱ were given hydragogue during the same time.We detected the left ventricular mass and the brachial artery dilatation induced by reactive hyperemia(DIRH)or nitroglycerin(DING)respectively with ultrasonography in all patients before and after treatment.25 normal subjects without any treatment were taken as the control. Results:The left ventricular mass index(LVMI)was higher in the two groups of patients[(133.61±31.02)g/m 2;(118.04±39.62)g/m 2]than that in the control(88.79±22.73)g/m 2 before treatment(P<0.01,0.000 1,respectively)while the blood pressure was higher.The DIRH was lower in the two groups of patients(5.93±2.24)%;(6.54±3.16)%than that in the control(13.09±2.99)%,P<0.000 1.There was no significantly differences in age,serum concentrations of total cholesterol,triglyceride,sugar,blood pressure or the DING between two groups of patients and the control(P>0.05).And there was no significant difference in the all variables between group Ⅰ and group Ⅱ before treatment.After treatment the LVMI decreased[(133.61±31.02)g/m 2 VS(91.07±16.01)g/m 2,P<0.01]and the DTRH increased[(5.93±2.24)% VS(13.53±2.38)%,P<0.01]in the patients of group Ⅰ while there was no significant change in LVMI and DIRH in the patients of group Ⅱ.The blood pressure in the two groups of patients was decreased to the normal.Compared with group Ⅱ,the changes of LVMI and DIRH was higher in patients of group Ⅰ though the serum concentrations of total cholesterol,triglyceride or sugar were not significantly different.No significant change in serum concentrations oftotal cholesterol,triglyceride or sugar was found during treatment in the two groups of patients.Analysis showed that the LVMI correlated with DIRH and the change of LVMI correlated better with the change of DIRH(r=-0.56;0.69,P<0.000 1,respectly). Conclusions: The increase of left ventricular mass was related with endothelial dysfunction in essential hypertension.Being independent of the changes of serum concentrations of total cholesterol,triglyceride or sugar and blood pressure,Simvastatin could inhibit the increase of left ventricular mass and improve endothelial function.
基金Project (No. 2003C13015) supported by the Key Project from Sci-ence and Technology Department of Zhejiang Province, China
文摘Objective: To investigate the immunological function of a yeast expression system for thymosin α1 (Tα1). Methods: A constructed Tetl yeast expression system was used to investigate the immunological function of orally administered Tα1. Dried yeast containing three different concentration of Tα1 was fed to normal Balb/c mice and other Balb/c mice whose immunities were inhibited in advance by cyclophosphamide. Synthesized Tα1 peptide was used as positive control and dried yeast with empty plasmid was used as negative control. CD4^+ and CD8^+ levels were detected by flow cytometry assay. TNF-α, IFN-γ, IL-2, IL-6 and IL-10 levels were detected by liquid chip. Results: In normal Balb/c mice or immune inhibition Balb/c mice, CD8^+ levels were significantly increased. Especially in immune inhibition Balb/c mice, CD8^+ levels in synthesized Tα1 group (18.77%±4.72%), small dose group (13.48%±6.17%) and large dose group (22.74%±1.09%) were significantly higher than that in empty yeast control group (7.49%±2.14%). Conclusion: Orally administered Tα1 has its certain immunomodulatory function.
基金supported by the National Natural Science Foundation of China under Grants No.61272499,No.10990011
文摘Signcryption, which was introduced by ZHEN~ is a cryptographic primitive that fulfils the functions of both digital signature and encryption and guarantees confidentiality, integrity and non-repudiation in a more effi- cient way. Certificateless signcryption and pro- xy signcryption in identity-based cryptography were proposed for different applications. Most of these schemes are constructed by bilinear pairings from elliptic curves. However, some schemes were recently presented without pai- rings. In this paper, we present a certificateless proxy identity-based signcryption scheme with- out bilinear pairings, which is efficient and secure.
文摘Among 180 patients with female urethral syndrome, 128 were treated by acupuncture and moxibustion and 52 by western medicine as controls. The short-term effective rate in the acupuncture and moxibustion group was 90.6% and the long-term effective rate, 80.4%; whereas the short-term effective rate of the control group was 26.9% (P 0.05). Sixty-nine cases from the acupuncture and moxibustion group and 39 from the control group were subjected before and after treatment to determinations of the maximal bladder pressure, maximal abdominal pressure, bladder-neck pressure, and maximal urethral closure pressure during urination. All these indexes were decreased remarkably in the acupuncture and moxibustion group, while no changes were observed in the control group.
文摘OBJECTIVE To evaluate the effect and safety of a Molecular Adsorbent Recycling System (MARS) in treating posthepatoectomy hepatic failure (AHF) patients surgically treated for primary hepatocellular carcinoma (HCC). METHODS 12 AHF patients induced by resection of HCC were treated with MARS before orthotopic liver transplantation (OLT). Their vital signs, urine volume, APACHElll and Glasgow scores were monitored. Routine laboratory blood tests, measurements of coagulatory function, liver and kidney function, serum ammonia, lactic acid and blood gas were conducted before and after treatment with MARS. All of the patients were followed up for a period of 6 months after OLT for prognosis and complication assessment. RESULTS Each patient was treated with MARS for 2-5 times (average of 3.6) with a length of 8-24 h each time. Their mean arterial blood pressure and urine volume were improved, APACHE III and Glasgow scores were better. Liver function was improved with the following alterations before and after treatment with MARS: serum ammonia (127.1±21.4 umol/L vs. 77.4±19.7 umol/L, P〈0.05), lactic acid (6.53±0.45 mmol/L vs. 3.75± 0.40 mmol/L, P〈0.05) and total bilirubin (452.3±153.7 umol/L vs. 230.9± 115.2 umol/L, P〈0.05). However, there was no significant change in platelet count (44.25±3.60×10^9/L vs. 43.19±8.26×10^9/L, P〉0.05) on international normalized ratio (INR) (2.74±0.50 vs. 2.82±0.60, P〉0.05), which showed the safety of MARS. For all patients no serious adverse effects occurred during the treatment with MARS. CONCLUSION MARS is effective and safe for treatment of AHF patients with HCC, especially as a bridge to OLT when a donor organ is not available.
文摘Anemia is the most common complication of inflammatory bowel disease (IBD). Control and inadequate treatment leads to a worse quality of life and increased morbidity and hospitalization. Blood loss, and to a lesser extent, malabsorption of iron are the main causes of iron def iciency in IBD. There is also a variable component of anemia related to chronic inflammation. The anemia of chronic renal failure has been treated for many years with recombinant human erythropoietin (rHuEPO), which significantly improves quality of life and survival. Subsequently, rHuEPO has been used progressively in other conditions that occur with anemia of chronic processes such as cancer, rheumatoid arthritis or IBD, and anemia associated with the treatment of hepatitis C virus. Erythropoietic agents complete the range of available therapeutic options for treatment of anemia associated with IBD, which begins by treating the basis of the inflammatory disease, along with intravenous iron therapy as f irst choice. In cases of resistance to treatment with iron, combined therapy with erythropoietic agents aims to achieve near-normal levels of hemoglobin/hematocrit (11-12 g/dL). New formulations of intravenous iron (iron carboxymaltose) and the new generation of erythropoietic agents (darbepoetin and continuous erythropoietin receptor activator) will allow better dosing with the same eff icacy and safety.
基金supported by the National Natural Science Foundation of China under Grant No.61100219the Fundamental Research Funds for the Central Universities under Grant No.2012JBM010the Key Program of National Natural Science Foundation of China under Grant No.60833002
文摘With the rapid development of Internet of Things (IoT),the issue of trust in distributed routing systems has attracted more research attention.The existing trust management frameworks,however,suffer from some possible attacks in hostile environments,such as false accusation,collusion,on-off,and conflicting behavior.Therefore,more comprehensive models should be proposed to predict the trust level of nodes on potential routes more precisely,and to defeat several kinds of possible attacks.This paper makes an attempt to design an attack-resistant trust management model based on beta function for distributed routing strategy in IoT.Our model can evaluate and propagate reputation in distributed routing systems.We first describe possible attacks on existing systems.Our model is then proposed to establish reliable trust relations between self-organized nodes and defeat possible attacks in distributed routing systems.We also propose a theoretical basis and skeleton of our model.Finally,some performance evaluations and security analyses are provided to show the effectiveness and robustness of our model compared with the existing systems.
文摘Kenneth Burke's rhetoric on language as a symbolic action offers an enlightening perspective for revealing the connection between the motivations and actions of the characters in Thomas Kyd's The Spanish Tragedy. This work is a Renaissance drama that features hues of rhetorical language. Linguistic obfuscation, scapegoat mechanism, and the malfunction and dysfunction of language in victimization and revenge are thrown into relief through Burke's elaborate system of the symbolism of language. Analyzing the discursive performances of the main characters, readers could get clues of their motives that drive their actions, which are both a representation and an illustration of how language as a symbolic action works in literature
文摘This paper presents an architecture of a hybrid recommender system in E-commerce environment. The goal of the system is to make special improvements in giving precisely personalized recommendation through some effective measures. Based on the study on the existing recommendation methods of both the conventional similarity function and the conventional feedback function, several improvement algorithms are developed to enhance the precision of recommendation, which include three improved similarity functions, four improved feedback functions, and adoption of both explicit and implicit preferences in individual user profile. Among them, issues and countermeasures of a new user, prominent preferences and long-term preferences are nicely addressed to gain better recommendation. The users preferences is so designed to be precisely captured by a user-side agent, and can make self-adjustment with explicit or implicit feedback.
基金supported by the Natural ScienceFoundation of China under Grant 61261015the 973 project 2013CB329104+3 种基金the Natural Science Foundation of China under Grant61372124,61363059,and 61302100the projects BK2011027the Natural Science Foundation of Gansu Province for Distinguished Young Scholars(1308RJDA007)the Foundation Research Funds for the University of Gansu Province:'Massive MIMO channels modeling and estimation over millimeter wave band for 5G'
文摘Abstract: This paper focuses on the first-or- der and second-order performance of dual-hop underlay cognitive radio systems with oppor- tunistic relaying (UCR-OR) over indepen- dent and non-identically distributed (i.ni.d) Rayleigh fading channels. For the UCR-OR systems, the tolerable maximum interference power (TMIP) Q at primary users (PUs) and the allowable maximum transmission power limit (AMTP) P at secondary users (SUs) are considered, simultaneously. We first obtain the closed-form solutions to the first-order performance such as outage probability, ave- rage symbol error ratio (SER), and ergodic capacity (EC). Secondly, we investigate the second-order statistical performance, i.e., ave- rage outage rate (AOR) and average outage duration (AOD). With the consideration that in practice implementation the receiver perfor- mance is primarily influenced by the signal- to-noise ratio (SNR) (not the signal envelope), the second-order statistical performance is investigated based on the equivalent instan- taneous end-to-end SNR. Finally, we present the detailed performance comparison analysis of UCR-OR systems by defining a random variable ,μ=Pmax/Q. The results show that the effect of μ on the first-order and second-or- der performances is different greatly. For the first-order performance, the perlbrmance gap is negligible when the value of// is relatively large. However, for the second-order one, the gap is distinct.
文摘The fast excitation system of a composite magnetic controllable reactor is introduced. In this excitation system, a bidirectional function (i.e. fast forward excitation and backward forcible demagnetization) is available, which can significantly improve the response speed, performances, and application scope of magnetic controllable reactor.
基金Supported by National Natural Science Foundation of China (No.60501005)Key Programof Tianjin Science Technology Support Plan(No.2007-68)
文摘Gait recognition is the key question of functional electrical stimulation (FES) system control for paraplegic walking. A new risk-tendency-graph (RTG) method was proposed to recognize the stability information in FES-assisted walking gait. The main instrument was a specialized walker dynamometer system based on a multi-channel strain-gauge bridge network fixed on the walker frame. During walking process, this system collected the reaction forces between patient's upper extremities and walker and converted them into RTG morphologic curves of dynamic gait stability in temporal and spatial domains. To demonstrate the potential usefulness of RTG, preliminary clinical trials were done with paraplegic patients. The gait stability levels of two walking cases with 4- and 12-week FES training from one subject were quantified (0.43 and 0.19) from the results of temporal and spatial RTG. Relevant instable phases in gait cycle and dangerous inclinations of patient's body during walking process were also brought forward. In conclusion, the new RTG method is practical for distinguishing more useful gait stability information for FES system control.
文摘Objective To assess the sensitivity of high-resolution CT (HRCT) in detecting pulmonary involvement attributed to systemic lupus erythematosus (SLE). Methods Plain chest radiography, HRCT, and pulmonary function testing of 36 patients with SLE were analyzed. Results The sensitivity of the pulmonary involvement by HRCT, plain chest radiography and pulmonary function testing were 88.9%,36.1%,and 33.3%, respectively. Conclusion HRCT played an important role in detecting pulmonary involvemen due to SLE, especially in early and mild cases.
文摘In order to improve the accuracy of English teaching quality evaluation, so as to promote the quality of English teaching, an evaluation method of English teaching quality is proposed based on fuzzy comprehensive evaluation, the index system model of English teaching quality evaluation is constructed, a decision tree model is used for construction of English teaching quality index model, objective function of English teaching quality evaluation is constructed based on fuzzy decision model, the conjugate function analysis method is used to optimize the decision function, the attributes that can reflect the quality of English Teaching is extracted, accurate evaluation and prediction of English teaching quality are realized. The simulation results show that the method of English teaching quality evaluation is reliable, it has high degree of confidence, evaluation result is accurate.
文摘The performance of the power assist, global optimization solved by dynamic programming (DP) method, Chery and Insight control strategies are analyzed using the mild parallel hybrid electric vehicle (PHEV) model based on Insight structure. The influence of the four control strategies to the load power of the electric motor system used on parallel hybrid electric vehicle is studied. It is found that 80 percent of the motor load power points are under 1/5 of the electric peak power. The motor load power of the power assist control strategy is distributed in the widest range during generating operation, and the motor load power of the global optimization control strategy has the smallest one.