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拟南芥冷害胁迫下基因表达谱的统合分析 被引量:1
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作者 徐兆华 吴为人 《华南农业大学学报》 CAS CSCD 北大核心 2013年第4期511-516,共6页
对4套不同来源的拟南芥冷胁迫芯片试验数据进行了统合分析,并与各试验单独分析的结果进行了比较.结果表明,那些在2个或2个以上试验中被同时检测到的"较可靠的"差异表达基因(Differentially expressed gene,DEG)大多数都能被... 对4套不同来源的拟南芥冷胁迫芯片试验数据进行了统合分析,并与各试验单独分析的结果进行了比较.结果表明,那些在2个或2个以上试验中被同时检测到的"较可靠的"差异表达基因(Differentially expressed gene,DEG)大多数都能被统合分析检测出来,而那些只在1个试验中被检测到的"较不可靠的"DEG则大约只有1/4被统合分析检测到,说明统合分析适合于检测"较可靠的"DEG.在统合分析检测到的DEG中,约有9%是未被单独分析检测到的,其中包含6个与冷害胁迫直接相关的基因,说明统合分析还可以检测到被单独分析忽略的DEG.基因本体和启动子基序分析显示,统合分析检测到的DEG确实与冷胁迫有着密切的关系. 展开更多
关键词 冷胁迫 微阵列 差异表达基因 统合分析
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性的统合分析 被引量:4
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作者 吴敏伦 邓明昱(初译) 丘爱芝(校译) 《中国性科学》 2010年第11期37-41,共5页
当代的社会心理学理论(含性学理论),很大程度上是经过对临床/非临床的观察结果或资料进行汇总和分析后得出的。一个最佳的例子就是心理分析理论及其派生理论,这些理论基本上可被视为是对性及其相互关系所进行的传统"统合分析"... 当代的社会心理学理论(含性学理论),很大程度上是经过对临床/非临床的观察结果或资料进行汇总和分析后得出的。一个最佳的例子就是心理分析理论及其派生理论,这些理论基本上可被视为是对性及其相互关系所进行的传统"统合分析"(meta analysis)。自此以后,其他许多社会心理理论也蓬勃发展,而且还有诸多建树,但就其方法论而言,大致仍在传统的统合分析的框架内。随着人类在科学思维方面的进步,随着研究工作越来越多地使用统计和数学手段,过去10多年来,现代统合分析已经面目一新;它着力找出传统统合分析中的漏洞,并加以克服。时至今日,在实证医学界,在评估各种理论和治疗方法时,统合分析已经成为重要的准绳之一,并已结出丰硕的、富有启发性的果实。然而,在性学方面,统合分析仍鲜有应用。本文列举了性学方面一些最新的统合分析案例;这些案例有一部分是由我的同事和我本人操作的。从中可看出现代统合分析是如何对社会心理精神病学做出前景喜人的贡献的。然而,另一方面,仍有某些严重的问题亟待解决。 展开更多
关键词 性学 统合分析
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景区类型对游客感知和满意度关系的调节效应研究——基于统合分析的取向 被引量:3
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作者 张安民 《旅游论坛》 2013年第1期24-28,共5页
运用统合分析法,对过去所积累的有关国内游客感知和满意关系的文献进行客观的分析,以了解二者之间相关程度的大小,以及景区类型对二者相关系数的调节效应。经文献检索、溯洄法,共收集到26篇符合要求的定量研究文献,最后将资料以软件HLM... 运用统合分析法,对过去所积累的有关国内游客感知和满意关系的文献进行客观的分析,以了解二者之间相关程度的大小,以及景区类型对二者相关系数的调节效应。经文献检索、溯洄法,共收集到26篇符合要求的定量研究文献,最后将资料以软件HLM7.0和SPSS12.0进行分析。研究结果显示,总体上游客在景区的实际感知对其满意度有显著的正向影响,但不同类型的景区,游客感知和满意度相关系数的变异程度比较大,景区类型对游客感知和满意度相关系数有显著的正向调节效应,其解释了方差变异的3.55%。具体而言,风景名胜类景区的游客感知和满意度之间的相关系数最大,文化古迹类景区游客感知和满意度之间的相关系数最小。但研究也发现,除景区类型调节因素外,可能还存在其他高水平变量可以解释游客感知和满意度相关系数的变异。 展开更多
关键词 游客感知 游客满意度 景区类型 统合分析
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复原力保护因子效果概化之统合分析
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作者 曾文志(Wen-Chih Tseng) 《諮商輔導學報:高師輔導所刊》
本研究收集1970至2004年来相关复原力保护因子的研究,运用统合分析技术,计算复原力保护因子的效果量,以概括诠释过去实徵性之复原力保护因子量化研究的发展。统合分析结果指出,复原力的型态不仅建立在多样化的逆境内涵,包括生物性... 本研究收集1970至2004年来相关复原力保护因子的研究,运用统合分析技术,计算复原力保护因子的效果量,以概括诠释过去实徵性之复原力保护因子量化研究的发展。统合分析结果指出,复原力的型态不仅建立在多样化的逆境内涵,包括生物性的、心理性的、社会性的危机,同时复原力型态更重要的架构在於,尽管这些重大逆境可能对个体发展造成相当程度的负面冲击,个体仍然能够维持良好的能力,包括认知、心理以及社会方面的健全适应。其中,有助於逆境中的个体维持正向适应的保护因子经过统合分析,研究发现共有14项具有精确效果量的保护因子与7项效果量不够稳定的保护因子,涵盖在个人特质、家庭联结、与外在支持等不同层面。在外在系统层面上,家庭与外在联结这项保护因子呈现中上且精确的效果量,是最为显着的保护因子。在个人特质上,自尊这项保护因子效果量的不稳定性,呈现具有需要更进一步去探讨的意义。而外在系统的同侪社会性与个人特质的挫折忍受力这两项保护因子,则呈现效果量最大但却不够稳定的结果。根据这些结论,本研究针对预防与介入研究,以及针对未来的复原力研究,提供具体建议,另外也提出本研究结果有所限制之处。 展开更多
关键词 復原力 危機因子 保護因子 正向適應 分析
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基于玉米综合QTL图谱的比较分析及株高QTL的统合分析 被引量:22
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作者 王毅 姚骥 +1 位作者 张征锋 郑用琏 《科学通报》 EI CAS CSCD 北大核心 2006年第15期1776-1786,共11页
以高密度遗传图IBM2Neighbors整合公开发表的、控制68个性状的1201个玉米QTL,构建了用于分子标记发掘、QTL定位、基因克隆及分子标记辅助选择的综合图谱,并将结果融入本地化数据库CMap软件.利用CMap比较玉米QTL综合图和水稻QTL图谱发现... 以高密度遗传图IBM2Neighbors整合公开发表的、控制68个性状的1201个玉米QTL,构建了用于分子标记发掘、QTL定位、基因克隆及分子标记辅助选择的综合图谱,并将结果融入本地化数据库CMap软件.利用CMap比较玉米QTL综合图和水稻QTL图谱发现,玉米和水稻QTL成簇分布具有普遍性;22个玉米株高QTL与64个水稻株高QTL位于标记水平上的共线性区域,43个玉米产量QTL与7个水稻QTL位于标记水平上的共线性区域.以控制玉米株高的QTL为例,利用overview的分析方法对127个QTL进行优化,定位了40个“真实”QTL,提高了QTL定位的准确性和有效性,发现了玉米和水稻株高相关QTG(quantitativetraitgene)的候选基因.本研究为大量玉米QTL信息的有效利用搭建了重要的生物信息学平台. 展开更多
关键词 QTL整 比较定位 统合分析 QTL克隆
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汉语紧缩句句法、语义、语用统合分析:默认语义学视角 被引量:1
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作者 赵方铭 张绍杰 《外语学刊》 CSSCI 北大核心 2021年第2期59-64,共6页
汉语紧缩句研究至今已有一个世纪的历史,但以往研究重于对紧缩句句法、语义、语用单一层面的分析,忽视对其整体的认识。本文从默认语义学视角分析紧缩句识解过程中体现的句法、语义、语用多层面的互动关系,研究发现,紧缩句的识解过程通... 汉语紧缩句研究至今已有一个世纪的历史,但以往研究重于对紧缩句句法、语义、语用单一层面的分析,忽视对其整体的认识。本文从默认语义学视角分析紧缩句识解过程中体现的句法、语义、语用多层面的互动关系,研究发现,紧缩句的识解过程通过其3个层面的互动呈现出从逻辑关系语义表达到非逻辑关系默认义表达的意义连续统。本研究为探索紧缩句句法、语义、语用统合分析开辟新路径。 展开更多
关键词 紧缩句 默认语义学 统合分析 意义连续
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学习效能感、自我决定动机对学业期望的作用:基于统合模型的分析 被引量:7
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作者 马星杨 赵玉芳 +2 位作者 李元方 姚菲 龚宁馨 《心理技术与应用》 2021年第1期12-19,共8页
研究整群抽样山东某高中高二学生500人,通过统合模型分析自我决定动机在学习效能感预测学业期望中的作用。结果表明,学习效能感—自我决定动机—学业期望的模型与数据拟合良好,学生的学习效能感可以通过自我决定动机,正向预测其学业期望... 研究整群抽样山东某高中高二学生500人,通过统合模型分析自我决定动机在学习效能感预测学业期望中的作用。结果表明,学习效能感—自我决定动机—学业期望的模型与数据拟合良好,学生的学习效能感可以通过自我决定动机,正向预测其学业期望,自我决定动机在学习效能感和学业期望中起中介作用,非自我决定动机不能预测学业期望。说明学习效能感可能促进了学生自主性动机的内化,并使得学生产生更高的学业期望。 展开更多
关键词 自我决定动机 学习效能感 学业期望 模型分析
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玉米产量因子QTL整合图谱构建与“一致性”QTL确定 被引量:13
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作者 王晓丽 李新海 王振华 《核农学报》 CAS CSCD 北大核心 2008年第6期756-761,838,共7页
应用生物信息学手段,收集和整理了411个玉米产量及构成因子QTL相关信息,借助高密度玉米遗传图谱IBM2 2005 Neighbors,采用BioMercator2.1软件构建出含221个QTL的整合图谱。采用统合分析方法,在LOD值大于4.0时于玉米第6染色体上确定1个... 应用生物信息学手段,收集和整理了411个玉米产量及构成因子QTL相关信息,借助高密度玉米遗传图谱IBM2 2005 Neighbors,采用BioMercator2.1软件构建出含221个QTL的整合图谱。采用统合分析方法,在LOD值大于4.0时于玉米第6染色体上确定1个与穗数、粒重和单位籽粒产量相关的"一致性"QTL,由标记bnlg1732和bnl8.08c界定,间距14.51cM。从MaizeGDB网站下载"一致性"QTL区间内基因和标记的原始序列,通过NCBI网站在线软件BLASTx同源比对分析,初步获得3个产量位置候选基因。利用比较基因电子定位策略,将53个水稻和玉米产量相关基因定位到玉米IBM2 2005 Neighbors图谱上,在"一致性"QTL区间内发现1个控制水稻分蘖数基因,初步确定为产量位置候选基因。本文结果为确定有关玉米产量因子的QTL及其候选基因提供了信息。 展开更多
关键词 玉米 产量因子 数量性状位点(QTL) 图谱 统合分析
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关联图分析:一种基于连锁图的QTL综合分析方法 被引量:1
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作者 匡峰磊 汪霞 +1 位作者 周玲 章元明 《科学通报》 EI CAS CSCD 北大核心 2010年第29期2828-2836,共9页
通过统合分析整合多个独立实验QTL(quantitative trait locus)定位结果获得的一致性QTL,可为标记辅助育种和基因图位克隆提供坚实基础.但是这种方法没有充足的生物学背景支撑,而且遗传图谱间不同映射会严重影响分析结果.为此,本文提出... 通过统合分析整合多个独立实验QTL(quantitative trait locus)定位结果获得的一致性QTL,可为标记辅助育种和基因图位克隆提供坚实基础.但是这种方法没有充足的生物学背景支撑,而且遗传图谱间不同映射会严重影响分析结果.为此,本文提出一种基于连锁图的QTL综合分析法,简称关联图分析.首先,利用连锁群构建图模型;然后,利用非监督分类法来寻找基因组间具有模式性共分离趋势的标记区间;最后,通过频繁集挖掘法对这些标记区间挖掘以获得与QTL紧密连锁的分子标记(区间).新方法通过Monte Carlo模拟研究和3个棉花QTL定位结果的综合分析予以证实.新方法的优点在于:不需要构建参考图谱;利用基因组间的分子标记模式性共分离趋势来查找特异性QTL,在一定程度上排除了初始QTL的干扰;通过非特异性QTL获得的具有潜在育种价值的分子标记,在作物育种上更有利用价值. 展开更多
关键词 连锁图 数量性状基因座 统合分析 关联图分析
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Reliability Analysis of a Mixed Redundant Model in C 3I System 被引量:1
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作者 徐勇 侯朝桢 《Journal of Beijing Institute of Technology》 EI CAS 1999年第3期324-330,共7页
Aim To define a mixed redundant model(MRM), improving the reliability of C 3I system. Methods The model combined the technology characters of two? unit system with one warm stand by unit and function substitute s... Aim To define a mixed redundant model(MRM), improving the reliability of C 3I system. Methods The model combined the technology characters of two? unit system with one warm stand by unit and function substitute system. The reliability and availability equations of MRM were deduced. Results and Conclusion Compared with several other reliability models, it has obvious effect upon improving the system reliability. The effect? cost rate is very high among these models. The model can be used in reliability design, evaluation and check of C 3I system. Only a little attached cost is needed to improve C 3I system reliability effectively. 展开更多
关键词 C 3I system reliability analysis mixed redundant model
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Instantaneous rotation speed measurement and error analysis for variable speed hydraulic system 被引量:1
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作者 杨彬 谷立臣 +1 位作者 刘永 王平 《Journal of Measurement Science and Instrumentation》 CAS CSCD 2015年第4期315-321,共7页
In order to monitor the working state of piston motor and measure its instantaneous rotation speed accurately, the measuring principle and method of instantaneous rotation speed based on industrial personal computer a... In order to monitor the working state of piston motor and measure its instantaneous rotation speed accurately, the measuring principle and method of instantaneous rotation speed based on industrial personal computer and data acquisition card are introduced, and the major error source, influence mechanism and processing method of data quantization error are dis- cussed. By means of hybrid programming approach of LabVIEW and MATLAB, the instantaneous rotation speed measurement system for the piston motor in variable speed hydraulic system is designed. The simulation and experimental results show that the designed instantaneous speed measurement system is feasible. Furthermore, the sampling frequency has an important influ- ence on the instantaneous rotation speed measurement of piston motor and higher sampling frequency can lower quantization er- ror and improve measurement accuracy. 展开更多
关键词 variable speed hydraulic system instantaneous rotation speed measurement error analysis hybrid programming
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Simulation Research on Structure Changing Control over the Follow Up System of the Smart Mine
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作者 李杰 王琳 +1 位作者 孟嘉友 李世义 《Journal of Beijing Institute of Technology》 EI CAS 2000年第3期278-282,共5页
By analyzing the target's motion pattern, in terms of the requirement for the performance indexes of the follow up system, the structure changing control and time optimal theory is proposed. The system's co... By analyzing the target's motion pattern, in terms of the requirement for the performance indexes of the follow up system, the structure changing control and time optimal theory is proposed. The system's control scheme from three different aspects(the dynamic response simulation, compound control simulation and dynamic tracking simulation) is also studied. And all the results proved the feasibility of the synthetical utilization of the open loop control, speed decreased control and position closed loop control. 展开更多
关键词 structure changing control compound control CONTROLLER system analysis simulation
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Integration Level for the Association of Southeast Asian Nations (ASEAN) Economic Community 被引量:2
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作者 Sylvia Cristina Alvarado Navas 《Chinese Business Review》 2016年第2期55-63,共9页
The time has come for the constitution of the Association of Southeast Asian Nations (ASEAN) economic community and many facts have been analyzed regarding this topic. This paper presents the results of the statisti... The time has come for the constitution of the Association of Southeast Asian Nations (ASEAN) economic community and many facts have been analyzed regarding this topic. This paper presents the results of the statistical analysis applied to several economic parameters which firstly show how their integration pattern adjusts with a considerable good fitting to the optimum currency area model and to its extended version by Behrens; and secondly how the 10 members of this group are moving at relatively same speed in spite of their differences, that are also inferred for ranging. 展开更多
关键词 Association of Southeast Asian Nations (ASEAN) regional integration ASEAN members' economicdifferences and similarities currency harmonization optimum currency area (OCA)
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Nonlinear Coupled Analysis of a Single Point Mooring System 被引量:2
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作者 WANG Junrong LI Huajun LI Ping ZHOU Kai 《Journal of Ocean University of China》 SCIE CAS 2007年第3期310-314,共5页
Coupled effects on a single point mooring(SPM) system subjected to the combined action of wind,waves and current are studied in this paper. Due to the complicatedness of the sea state and the huge size of the vessel,p... Coupled effects on a single point mooring(SPM) system subjected to the combined action of wind,waves and current are studied in this paper. Due to the complicatedness of the sea state and the huge size of the vessel,physical experimental study is both time consuming and uneconomical,whereas the numerical study is cost-effective and DNV software provides powerful SESAM software in solving the issues. This paper focuses on the modeling process of the SPM system,catenary equilibrium calculation,static analysis of the vessel in three different scenarios,and dynamic response simulation of the SPM system under environmental excitations. The three scenarios in study are as follows:the SPM is under the combined function of(a) wind,waves and current,(b) wind and waves,(c) current and waves. They are so set that one can compare the contributions of different types of loads in both static and dynamic studies. Numerical study shows that wind and current are the two major factors contributing to the mooring line tension,and surge and sway are the two dominant motions of the moored vessel subjected to environmental excitations. 展开更多
关键词 single point mooring system response amplitude operator catenary equilibrium static analysis dynamic response
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New Resolution to Coupling Loss Factor of Beam Plate Structure
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作者 刘景泉 姚德源 《Journal of Beijing Institute of Technology》 EI CAS 2000年第3期267-272,共6页
The transmission of transverse vibrational energy of a vertically rigid beam plate coupled structure is analyzed to get the theoretical results of coupling loss factor(CLF), a very important parameter in statistical ... The transmission of transverse vibrational energy of a vertically rigid beam plate coupled structure is analyzed to get the theoretical results of coupling loss factor(CLF), a very important parameter in statistical energy analysis(SEA). The modal analysis method is used to discuss the vibration energy of the typical model, as well as the power flow between the two subsystems. Furthermore, the resolution to the coupling loss factor is also derived and compared with the measured values. The analytical results of the coupling loss factor agree with the measured ones fully, this new resolution is significant for the application of SEA. 展开更多
关键词 statistical energy analysis coupling loss factor modal analysis method
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Analysis of expressed sequence tags from the Ulva prolifera (Chlorophyta) 被引量:4
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作者 牛建峰 胡海岩 +3 位作者 胡松年 王广策 彭光 孙松 《Chinese Journal of Oceanology and Limnology》 SCIE CAS CSCD 2010年第1期26-36,共11页
In 2008, a green tide broke out before the sailing competition of the 29th Olympic Games in Qingdao. The causative species was determined to be Enteromorpha prolifera (Ulva prolifera O. F. Miiller), a familiar green... In 2008, a green tide broke out before the sailing competition of the 29th Olympic Games in Qingdao. The causative species was determined to be Enteromorpha prolifera (Ulva prolifera O. F. Miiller), a familiar green macroalga along the coastline of China. Rapid accumulation of a large biomass of floating U. prolifera prompted research on different aspects of this species. In this study, we constructed a nonnormalized cDNA library from the thalli of U. prolifera and acquired 10072 high-quality expressed sequence tags (ESTs). These ESTs were assembled into 3 519 nonredundant gene groups, including 1 446 clusters and 2 073 singletons. After annotation with the nr database, a large number of genes were found to be related with chloroplast and ribosomal protein, GO functional classification showed 1 418 ESTs participated in photosynthesis and 1 359 ESTs were responsible for the generation of precursor metabolites and energy. In addition, rather comprehensive carbon fixation pathways were found in U. prolifera using KEGG. Some stress-related and signal transduction-related genes were also found in this study. All the evidences displayed that U. prolifera had substance and energy foundation for the intense photosynthesis and the rapid proliferation. Phylogenetic analysis of cytochrome c oxidase subunit I revealed that this green-tide causative species is most closely affiliated to Pseudendoclonium akinetum (Ulvophyceae). 展开更多
关键词 green tide Ulva Prolifera expressed sequence tag (EST) filamentous green alga rapid growth PROLIFERATION
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Culture of Scenedesmus acuminatus in Corn Steep Liquor
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作者 Cristiane Tomas Kubo] Rafael Luan Sehn Canevest +2 位作者 Edson Antonio da Silva , Nyamien Yahaut Sebastien Tatiana Rodrigues da Silva Baumgartner 《Journal of Agricultural Science and Technology(B)》 2017年第5期346-350,共5页
Microalgae have been evaluated as a source of lipids for biodiesel production. They can be grown on effluent and produce biomass while removing organic and mineral components from the medium. The use of agro-industria... Microalgae have been evaluated as a source of lipids for biodiesel production. They can be grown on effluent and produce biomass while removing organic and mineral components from the medium. The use of agro-industrial wastes for the production of microalgae is an alternative to reduce the costs related to the composition of the culture medium, thus reducing operational costs considerably. This work was conceived as a research about the cultivation of microalgae Scenedesmus acuminatus on the substrate composed by corn steep liquor. A central composite design (CCD) was carried to study the influence of the effluent and inoculum concentration on the chemical oxygen demand (COD) of the culture. Statistical analysis indicated that the percentage of inoculum and effluent had an influence on the COD. The cultivation, together with the coagulation procedure, was efficient for the removal of organic matter, verified through the COD reduction and changing of pH value. These two parameters reached the appropriate level according to the standard required by current legislation. 展开更多
关键词 SCENEDESMUS com steep liquor chemical oxygen demand BIOMASS microalgae.
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STATISTICAL CHARACTERISTICS OF TROPICAL CYCLONES MAKING LANDFALLS AND PASSING THROUGH LAKES IN CHINA 被引量:2
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作者 王晓芳 《Journal of Tropical Meteorology》 SCIE 2009年第1期63-67,共5页
By using the data of 1949 – 2001 (53 years) of Tropical Cyclone (TC) Yearbooks, statistical analyses are performed to study the climatic features of TCs making landfall and then passing through lakes (hereafter refer... By using the data of 1949 – 2001 (53 years) of Tropical Cyclone (TC) Yearbooks, statistical analyses are performed to study the climatic features of TCs making landfall and then passing through lakes (hereafter referred to as "L-TCs") in China. Results show that L-TCs can sustain a long time over land and the intensity is very strong during the course of landfall. Lakes can noticeably slow down the reduction of TC intensity, with the minimum pressure mostly maintained or decreased and the maximum velocity increased. The middle reach of the Yangtze River has the biggest TC dissipating rate as compared with the other areas where the TC is active. 展开更多
关键词 climatology tropical cyclones statistic characteristics landfall lakes
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Analytical Solution of Weak-Coupling Periodically Driven Two-Level System
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作者 ZHOU Qing-Ping FANG Mao-Fa 《Communications in Theoretical Physics》 SCIE CAS CSCD 2008年第4期1025-1028,共4页
We present an approximate analytical solution to periodically driven two-level system in the weak-coupling regime. The analytical solution is in good agreement with the exact numerical solution in resonance and near r... We present an approximate analytical solution to periodically driven two-level system in the weak-coupling regime. The analytical solution is in good agreement with the exact numerical solution in resonance and near resonance cases when Ω 〈 0.3ωa with Ω and ωa denoting the Rabi and transition frequencies respectively. 展开更多
关键词 periodically driven two-level systems analytical solution weak-coupling regime
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The Chinese herbal Formula Tongxieyaofang for irritable bowel syndrome:a protocol for meta-analysis of randomized controlled trials
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作者 Cuncun Lu Zhijiang Bi +3 位作者 Kongyuan Wei Zhaochen Ji Long Ge Kehu Yang 《TMR Clinical Research》 2018年第1期20-24,共5页
Background:Irritable bowel syndrome(IBS)is a chronic functional bowel disorder characterized by abdominal pain and altered bowel function.The TongXieYaoFang(TXYF)is a Chinese herbal formula with a long history for the... Background:Irritable bowel syndrome(IBS)is a chronic functional bowel disorder characterized by abdominal pain and altered bowel function.The TongXieYaoFang(TXYF)is a Chinese herbal formula with a long history for the management of chronic diarrhea accompanied by abdominal pain,and it is always used to relieve symptoms of IBS.Although there are some studies were published,there is no consensus on its effects.Moreover,new relevant study was published recently.Therefore,a systematic review and meta-analysis is needed to assess the safety and eff ectiveness of the Chinese herbal medicine TongXieYaoFang for IBS.Methods and analysis:PubMed,EMBASE,the Cochrane library,CNKI,WanFang,VIP and CBM databases will be searched without search date and language restrictions.We will include randomized controlled trial(RCT)comparing TXYF with another therapy method for IBS.The quality of included studies will be independently assessed using Risk of bias tool in the Cochrane Handbook 5.1.0,and be categorized as being at low,unclear or high risk of bias.The primary outcome is the disappearance and significant improvement in global symptoms,and the secondary outcomes including visual analog scale(VAS)score,adverse event,rehospitalization rate and the quality of life.The Meta-analysis will be performed using the Cochrane Collection’s tool RevMan 5.3 software.Results:This study is ongoing and will be submitted to a peerreviewed journal for publication.Conclusion:This study will provide a confirmed evidence on the safety and eff ectiveness of TXYF for IBS.Ethics and dissemination:Ethical approval and patient consent are not required because of the study is a systematic review and meta-analysis based on literatures.The results of this study will be submitted to a peer-reviewed journal for publication. 展开更多
关键词 Tongxieyaofang Irritable bowel syndrome Systematic review META-ANALYSIS
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