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新药开发信息——盐酸西维米林
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《中国新药杂志》 CAS CSCD 北大核心 2003年第5期397-397,共1页
关键词 盐酸西维米 斯耶格伦综合征 口干症 胶囊剂 口服 处方药
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多元面相与都市“怪物”:论柴纳·米耶维的都市“新怪谭”
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作者 王一平 温馨 《广州大学学报(社会科学版)》 2024年第5期95-104,共10页
英国作家柴纳·米耶维是当代科幻“新怪谭”潮流中最重要的作家之一。在米耶维的《鼠王》《伪伦敦》《新巴黎的最后时光》等作品中,作者或想象了伦敦的鼠族等非人族群,或描绘了由被弃之物构成的“伪伦敦”,或展示了在巴黎获得生命... 英国作家柴纳·米耶维是当代科幻“新怪谭”潮流中最重要的作家之一。在米耶维的《鼠王》《伪伦敦》《新巴黎的最后时光》等作品中,作者或想象了伦敦的鼠族等非人族群,或描绘了由被弃之物构成的“伪伦敦”,或展示了在巴黎获得生命的“超现实主义艺术”中的“怪物”。由此,米耶维展现了怪诞可怖的都市面貌,展示了被隔离在人类的认知之外却又无处不在的“怪物他者”,破除了人类对城市的绝对占有式的、否弃多面性的观念,也迫使人们直面和承认内生的他者。同时,作品又赋予了这一多元混杂的都会以某种合法性,给予被科学和艺术等所催化出的怪物以生命——这些不被接受的怪物,往往与真正的“恶”进行着对抗。由此,米耶维提供了对多元都市面相的新奇审美体验,并否弃了托尔金式的作品中逃避现实的“抚慰”意味,强调通过对“多面世界”“怪物他者”的书写,来观照甚至改变现实,达成某种乌托邦理想。 展开更多
关键词 柴纳· 科幻 怪谭 《鼠王》 《伪伦敦》 《新巴黎的最后时光》
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《维锌硒米研究》总结报告 被引量:1
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作者 颜送贵 邓正春 +3 位作者 喻米玲 吴平安 李丕炎 江克平 《中国城市经济》 2011年第3X期317-317,共1页
用"优质稻+维生素锌硒肥+维锌硒米生产技术操作规程",可以提高大米有机硒、锌、镁等矿物质营养和B簇维生素营养的含量。研究结果表明:在水稻破口期、乳熟期各喷布1次700倍的维生素锌硒肥,生产出的纯天然维锌硒米,每天食用300... 用"优质稻+维生素锌硒肥+维锌硒米生产技术操作规程",可以提高大米有机硒、锌、镁等矿物质营养和B簇维生素营养的含量。研究结果表明:在水稻破口期、乳熟期各喷布1次700倍的维生素锌硒肥,生产出的纯天然维锌硒米,每天食用300g维锌硒米,在充分补足了硒的同时,还补足了铁、锌、镁和维生素。 展开更多
关键词 水稻 生素 产量 品质 锌硒
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维拉帕米对触发活性的影响
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作者 蒋廷波 蒋文平 《中国循环杂志》 CSCD 1993年第3期157-159,共3页
本文使用经典细胞电生理方法,观察维拉帕米对后除极电位和触发活性的影响。4mMBa^(2+)灌注后,心肌标本(n=11)膜电位由83.1±4.4mV降至62.1±3.5mV,动作电位幅值也由119.3±10.1mV降至74.0±6.9mV,表现异常自律性占27.3%... 本文使用经典细胞电生理方法,观察维拉帕米对后除极电位和触发活性的影响。4mMBa^(2+)灌注后,心肌标本(n=11)膜电位由83.1±4.4mV降至62.1±3.5mV,动作电位幅值也由119.3±10.1mV降至74.0±6.9mV,表现异常自律性占27.3%(3/11),EAD和DAD触发活性分别占45.4%(5/11)、27.3%(3/11)。维拉帕米灌注(1mg/L)后异常自律性明显减慢,EAD、DAD及相关的触发活性随之消失。这提示,异常自律性和触发活性可能与钙内流有关,维拉帕米具抑制作用。 展开更多
关键词 后除极电位 触发活性 帕拉
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硝苯地平、维拉帕米和地尔硫的副作用 被引量:1
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作者 张连平 张峥嵘 《人民军医》 北大核心 1999年第9期533-534,共2页
关键词 硝苯地平 位帕 地尔硫ZHUO 药物副作用
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耗散诱导的非厄米边缘爆发重现
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作者 任翠翠 尹相国 《物理学报》 SCIE EI CAS CSCD 北大核心 2023年第16期34-43,共10页
开放量子系统在一定程度上可由等效的非厄米哈密顿量来描述,因此探究非厄米系统的耗散作用有许多重要的现实意义.本文研究了开边界条件下一维非厄米系统中与耗散强度相关的动力学规律,发现耗散可诱导边缘爆发重新出现.粒子在开边界条件... 开放量子系统在一定程度上可由等效的非厄米哈密顿量来描述,因此探究非厄米系统的耗散作用有许多重要的现实意义.本文研究了开边界条件下一维非厄米系统中与耗散强度相关的动力学规律,发现耗散可诱导边缘爆发重新出现.粒子在开边界条件下的一维非厄米耗散晶格系统中进行含时演化后,系统存在边缘爆发即在边缘处有较大的粒子损失概率,而增大胞内跃迁强度后边缘爆发消失,研究发现若增大或者减小耗散强度,边缘爆发会重新出现.这种重现的与原先的边缘爆发有所不同,主要表现为粒子的损失概率分布由边缘分布趋向于体分布,这是由于两种情况下粒子运动方向的概率不同;更深层的原因与非厄米系统远离宇称-时间对称破缺点有关.另外还研究了杂质势垒对非厄米动力学中粒子损失概率分布的影响,结果表明在无耗散的A格点上放置很小的势垒就能明显地阻碍粒子运动,并且当势垒增大到一定高度后,其对粒子运动的影响趋于不变. 展开更多
关键词 非厄系统 耗散 势垒 边缘爆发
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In-situ thermal Raman mapping and stress analysis of CNT/CF/epoxy interfaces
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作者 HE Jing-zong CHEN Shi +2 位作者 MA Zheng-kun LU Yong-gen WU Qi-lin 《新型炭材料(中英文)》 SCIE EI CAS CSCD 北大核心 2024年第4期703-714,共12页
A study of the interfacial behavior and internal thermal stress distribution in fiber-reinforced composites is essential to assess their performance and reliability.CNT/carbon fiber(CF)hybrid fibers were constructed u... A study of the interfacial behavior and internal thermal stress distribution in fiber-reinforced composites is essential to assess their performance and reliability.CNT/carbon fiber(CF)hybrid fibers were constructed using electrophoretic deposition.The interfacial properties of CF/epoxy and CNT/CF/epoxy composites were statistically investigated and compared using in-situ thermal Raman mapping by dispersing CNTs as a Raman sensing medium(CNT_(R))in a resin.The associated local thermal stress changes can be simulated by capturing the G'band position distribution of CNT_(R) in the epoxy at different temperatures.It was found that the G'band shifted to lower positions with increasing temperature,reaching a maximum difference of 2.43 cm^(−1) at 100℃.The interfacial bonding between CNT/CF and the matrix and the stress distribution and changes during heat treatment(20-100℃)were investig-ated in detail.This work is important for studying thermal stress in fiber-reinforced composites by in-situ thermal Raman mapping technology. 展开更多
关键词 Thermal Raman mapping Stress distribution Carbon fiber Carbon nanotube Interface
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Mesoporous Carbon Nanofibers Loaded with Ordered PtFe Alloy Nanoparticles for Electrocatalytic Nitrate Reduction to Ammonia
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作者 XIE Meng LUO Wei QIU Pengpeng 《Journal of Donghua University(English Edition)》 CAS 2024年第4期365-376,共12页
Highly dispersed bimetallic alloy nanoparticle electrocatalysts have been demonstrated to exhibit exceptional performance in driving the nitrate reduction reaction(NO_(3)RR)to generate ammonia(NH_(3)).In this study,we... Highly dispersed bimetallic alloy nanoparticle electrocatalysts have been demonstrated to exhibit exceptional performance in driving the nitrate reduction reaction(NO_(3)RR)to generate ammonia(NH_(3)).In this study,we prepared mesoporous carbon nanofibers(mCNFs)functionalized with ordered PtFe alloys(O-PtFe-mCNFs)by a composite micelle interface-induced co-assembly method using poly(ethylene oxide)-block-polystyrene(PEO-b-PS)as a template.When employed as electrocatalysts,O-PtFe-mCNFs exhibited superior electrocatalytic performance for the NO_(3RR)compared to the mCNFs functionalized with disordered PtFe alloys(D-PtFe-mCNFs).Notably,the NH_(3)production performance was particularly outstanding,with a maximum NH_(3)yield of up to 959.6μmol/(h·cm~2).Furthermore,the Faraday efficiency(FE)was even 88.0%at-0.4 V vs.reversible hydrogen electrode(RHE).This finding provides compelling evidence of the potential of ordered PtFe alloy catalysts for the electrocatalytic NO_(3)RR. 展开更多
关键词 ordered PtFe alloy mesoporous carbon nanofiber(mCNF) nitrate reduction reaction(NO3RR) ammonia(NH3)production reaction
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Synthesis of one-dimensional carbon nanostructures and their application as anode materials in lithium ion batteries 被引量:3
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作者 唐晶晶 杨娟 +2 位作者 周向阳 陈光辉 黄滨 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2014年第4期1079-1085,共7页
An efficient synthesis of carbon nanofibers by pyrolysis of as-prepared polypyrrole nanowires was reported. Under the subsequent KOH activation, a significant morphology variation was detected and the obtained sample ... An efficient synthesis of carbon nanofibers by pyrolysis of as-prepared polypyrrole nanowires was reported. Under the subsequent KOH activation, a significant morphology variation was detected and the obtained sample took on a ribbon-like structure. The morphology and structure of the carbon nanofibers and carbon nanoribbons were characterized. When the as-prepared one-dimensional carbon nanostructures were used as anode materials in lithium ion batteries, both of them exhibited superior cyclical stability and good rate properties. After 50 cycles, the reversible capacity of carbon nanofibers electrode maintained 530 mA·h/g. Concerning carbon nanoribbons, the reversible capacity is always larger than 850 mA·h/g and the reversible capacity retention after 23 cycles is 86%. 展开更多
关键词 carbon nanofibers carbon nanoribbons PYROLYSIS KOH activation lithium ion batteries
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Recent advances in immobilized enzymes on nanocarriers 被引量:12
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作者 曹诗林 徐培 +5 位作者 马永正 姚潇晓 姚远 宗敏华 李雪辉 娄文勇 《Chinese Journal of Catalysis》 SCIE EI CAS CSCD 北大核心 2016年第11期1814-1823,共10页
Recent progress in nanotechnology has provided high-performance nanomaterials for enzyme immobilization.Nanobiocatalysts combining enzymes and nanocarriers are drawing increasing attention because of their high cataly... Recent progress in nanotechnology has provided high-performance nanomaterials for enzyme immobilization.Nanobiocatalysts combining enzymes and nanocarriers are drawing increasing attention because of their high catalytic performance,enhanced stabilities,improved enzyme-substrate affinities,and reusabilities.Many studies have been performed to investigate the efficient use of cellulose nanocrystals,polydopamine-based nanomaterials,and synthetic polymer nanogels for enzyme immobilization.Various nanobiocatalysts are highlighted in this review,with the emphasis on the design,preparation,properties,and potential applications of nanoscale enzyme carriers and nanobiocatalysts. 展开更多
关键词 Enzyme immobilization Cellulose nanocrystal POLYDOPAMINE Biodegradable material
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Thermodynamics analysis of Ni^(2+)-C_2H_8N_2- C_2O_4^(2-)-H_2O system and preparation of Ni microfiber 被引量:1
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作者 姚永林 张传福 +2 位作者 湛菁 丁风华 邬建辉 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2013年第11期3456-3461,共6页
According to the principles of simultaneous equilibrium and mass equilibrium, the thermodynamics model of the precipitation-coordination equilibrium of Ni2+-C2H8N2- 2-2 4C O -H2O system was established, and calculati... According to the principles of simultaneous equilibrium and mass equilibrium, the thermodynamics model of the precipitation-coordination equilibrium of Ni2+-C2H8N2- 2-2 4C O -H2O system was established, and calculation for the relationships between concentration of each substance in solution and parameters was carried out, including pH value, concentrations of ethylenediamine and oxalate by MATLAB program. The results show that Ni exists as Ni2+and [Ni(C2O4)n]2-2n mainly at pH〈1 and pH=1-6, respectively. When pH〉6, the complex between Ni2+and ethylenediamine is predominant. The precursor of Ni microfiber was prepared by an oxalate precipitation process using ethylenediamine as a coordination agent, and the role of ethylenediamine in the growth of the precursor fiber was discussed. The Ni microfiber can be obtained by a thermal decomposition-reduction process of the precursor in N2 and H2 mixed atmosphere. The diameters and aspect ratios of the obtained Ni microfibers are 0.2-1 μm and 20-30, respectively. 展开更多
关键词 thermodynamics analysis Ni microfiber PRECURSOR thermal decomposition REDUCTION
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Flexural destructive process of unidirectional carbon/carbon composites reinforced with in situ grown carbon nanofibers 被引量:2
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作者 卢雪峰 肖鹏 +1 位作者 徐先锋 陈洁 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2014年第10期3134-3141,共8页
Unidirectional carbon/carbon(C/C) composites modified with in situ grown carbon nanofibers(CNFs) were prepared by catalysis chemical vapor deposition. The effect of in situ grown CNFs on the flexural properties of... Unidirectional carbon/carbon(C/C) composites modified with in situ grown carbon nanofibers(CNFs) were prepared by catalysis chemical vapor deposition. The effect of in situ grown CNFs on the flexural properties of the C/C composites was investigated by detailed analyses of destructive process. The results show that there is a sharp increase in the flexural load-displacement curve in the axial direction of the CNF-C/C composites, followed by a serrated yielding phenomenon similar to the plastic materials. The failure mode of the C/C composites modified with in situ grown CNFs is changed from the pull-out of single fiber to the breaking of fiber bundles. The existence of interfacial layer composed by middle-textured pyrocarbon, CNFs and high-textured pyrocarbon can block the crack propagation and change the propagation direction of the main crack, which leads to the higher flexural strength and modulus of C/C composites. 展开更多
关键词 carbon nanofiber C/C composites flexural destruction crack propagation
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卢浮宫-朗斯:煤渣地上的象牙塔 被引量:1
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作者 韩晶 《当代美术家》 2014年第2期86-89,共4页
卢浮宫在朗斯开设了新分馆?在这个除了一堆19世纪左拉年代的破旧房子外,一无所有的荒凉地界?在这个被编号的"筒子楼"组成的煤渣地上?在这个很多人眼中,被烙印上"穷人辖区"的城市?不错,就是这个法国最穷的地区,法兰... 卢浮宫在朗斯开设了新分馆?在这个除了一堆19世纪左拉年代的破旧房子外,一无所有的荒凉地界?在这个被编号的"筒子楼"组成的煤渣地上?在这个很多人眼中,被烙印上"穷人辖区"的城市?不错,就是这个法国最穷的地区,法兰西把它最骄傲的文化地标——卢浮宫的分馆,选择在了这个无处不显现着战争和经济危机创伤的城市。并要把自己最重量级的部分藏品,带到这个备受瞩目的玻璃构造的建筑新馆之中。因为朗斯不是荒漠,选址时。 展开更多
关键词 朗斯 文化地标 左拉 维米 波提切利 马蒂斯 普桑 临时展馆 毕尔巴鄂 伦勃朗
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Determination of phthalate esters in fat-containing foods by packed nanofiber solid-phase extraction column and gas chromatography 被引量:1
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作者 邱金丽 王羽 +1 位作者 周小玲 康学军 《Journal of Southeast University(English Edition)》 EI CAS 2016年第3期322-326,共5页
A new method for simultaneous determination of four phthalate esters ( PAEs) in commercial fat-containing foods was developed by the combination of a packed nanofibers column based on solid-phase extraction with gas... A new method for simultaneous determination of four phthalate esters ( PAEs) in commercial fat-containing foods was developed by the combination of a packed nanofibers column based on solid-phase extraction with gas chromatography-flame ionization detector ( GC-FID ). Conditions for obtaining optimum extraction efficiency such as extraction solvents, morphologies of adsorbent, ion strength and pH were investigated and optimized in detail. Under the optimized conditions, the limits of detection (LODs) found for dibutyl phthalate (DBP) , butyl benzyl phthalate (BBP), diethyl hexyl phthalate (DEHP) and di-n-octyl phthalate (DNOP) were 50, 25, 50 and 25 ng/g, respectively. Good linearity of four PAEs was achieved in the range of 50 to 4 000 ng/g. The proposed method was applied for analyzing different kinds of fat-containing samples. PAEs in commercial fat-containing samples can be highly extracted by a packed solid-phase extraction column of 5 mg polystyrene ( PS) nanofibers. The satisfactory average recoveries were obtained in the range of 96. 7% to 102. 3% , and the relative standard deviations (RSDs) below 5% were achieved. The proposed method reduces the organic solvent consumption, the complex and tedious procedures for sample pretreatment, and achieves high sensitivity and reproducibility for the investigated PAEs. 展开更多
关键词 phthalate esters (PAEs nanofibers solid-phase extraction gas chromatography fat-containing foods
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Using 3D TCAD Simulation to Study Charge Collection of a p-n Junction in a 0.18μm Bulk Process
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作者 梁斌 陈书明 刘必慰 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2008年第9期1692-1697,共6页
Single event transient of a real p-n junction in a 0.18μm bulk process is studied by 3D TCAD simulation. The impact of voltage, temperature, substrate concentration, and LET on SET is studied. Our simulation results ... Single event transient of a real p-n junction in a 0.18μm bulk process is studied by 3D TCAD simulation. The impact of voltage, temperature, substrate concentration, and LET on SET is studied. Our simulation results demonstrate that biases in the range 1.62 to 1.98V influence DSET current shape greatly and total collected charge weakly. Peak current and charge collection within 2ns decreases as temperature increases,and temperature has a stronger influence on SET currents than on total charge. Typical variation of substrate concentration in modern VDSM processes has a negligible effect on SEEs. Both peak current and total collection charge increases as LET increases. 展开更多
关键词 charge collection p-n junction very deep sub-micro 3D device simulation RADIATION
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Effects of 2-[p-(Dimethylamino)Styrl] PyridineMethiodide on Slow Response Action Potentialand Slow lnward Current of Guinea PigPapillary Muscles
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作者 毛新民 李迪民 +2 位作者 周承明 王晓雯 张克锦 《Journal of Chinese Pharmaceutical Sciences》 CAS 1995年第1期12-16,共5页
The effects of 2-[p-(Dimethylamino)styryl] pyridine methiodide(DSPM)on slow response action potential(SRAP)and slow inward current(Isi) of guinea pig papillary muscles were studied by intracellular microelectrodes and... The effects of 2-[p-(Dimethylamino)styryl] pyridine methiodide(DSPM)on slow response action potential(SRAP)and slow inward current(Isi) of guinea pig papillary muscles were studied by intracellular microelectrodes and voltage clamp techniques.The APA and V_(max) of SRAP induced by high K ̄+were decreased after 50 min of perfusion with DSPM solu- tion. Isi was suppressed from a peak value of8.8± 1.6μA to 5.7± 1.8μA, The results indicated that DSPM has a selective blocking effect on calcium channel. 展开更多
关键词 p-(Dimethylamino)styryl] pyridine methiodide(DSPM) Verapamil Calcium chloride Papillary muscle Calcium channel Voltage clamp Action potential
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英氏果乐维 首尝米粉 全新升级步入英氏《一年级》
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《时尚育儿》 2014年第12期97-97,共1页
小朋友从幼儿园步入《一年级》是一个质的飞跃,就像妈妈对宝宝的喂养从母乳到辅食的进一步营养给予,是育儿能力的提升。《一年级》是湖南卫视最新打造的一档大型原创校园纪实节目,自2014年10月17日首播起便在互联网引起了热议。2014年11... 小朋友从幼儿园步入《一年级》是一个质的飞跃,就像妈妈对宝宝的喂养从母乳到辅食的进一步营养给予,是育儿能力的提升。《一年级》是湖南卫视最新打造的一档大型原创校园纪实节目,自2014年10月17日首播起便在互联网引起了热议。2014年11月,《英氏育儿一年级升学考试》即将在各大母婴网站全面上线,通过营养科、美术科、地理科等课程赢取英氏营养米粉大礼包,还有《英氏育儿一年级班干部有奖评选》微信游戏,大家敬请参与! 展开更多
关键词 营养科 升学考试 班干部 维米 东北大 追溯系统 质检报告 辅食添加 步营 胚芽
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感受“十三个最美丽的人”
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作者 罗韵啸 《音乐爱好者》 2016年第7期33-34,共2页
他是波普艺术的倡导者和领袖,他被誉为二十世纪艺术界最有名的人物之一,他是电影制片人,作家,摇滚乐作曲者、设计师、出版商,是纽约社交界、艺术界大红大紫的明星式艺术家。他就是安迪·沃霍尔(Andy Warhol)安迪·沃霍尔从小... 他是波普艺术的倡导者和领袖,他被誉为二十世纪艺术界最有名的人物之一,他是电影制片人,作家,摇滚乐作曲者、设计师、出版商,是纽约社交界、艺术界大红大紫的明星式艺术家。他就是安迪·沃霍尔(Andy Warhol)安迪·沃霍尔从小酷爱绘画,年轻时就以一系列具有商业化风格的贺卡、橱窗展示、商业广告插图而闻名纽约。他在著名工作室“工厂”内聘请了工作团队。 展开更多
关键词 沃霍尔 安迪 波普艺术 广告插图 电影制片 作曲者 工作团队 维米 橱窗展示 古典艺术
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Antineoplastic Effect of Calcium Channel Blocker-Verapamil and 5-Fluorouracil Intraperitoneal Chemotherapy on Hepatocarcinoma-Bearing Rats
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作者 曹天生 史海安 周亚魁 《The Chinese-German Journal of Clinical Oncology》 CAS 2002年第2期84-87,共4页
Objective To study the antineoplastic effect of the calcium channel blocker verapamil and 5-fluorouracil intraperitoneal chemotherapy onhepatocarcinoma-bearing rats, and examine the action between calcium channel bloc... Objective To study the antineoplastic effect of the calcium channel blocker verapamil and 5-fluorouracil intraperitoneal chemotherapy onhepatocarcinoma-bearing rats, and examine the action between calcium channel blockers and cytotoxic drugs.Methods We adopted the method of subcapsular implantation of carcinoma tissues of walker-256 in the left liver lobe as a model of livercarcinoma-bearing rats. All experimental animals were divided into four groups. On the sixth day post implantation, in group A (controlgroup) 6 ml of saline was injected intraperitoneally once a day for 3 days. In group B (single chemotherapy group) 6 ml of 5-Fu 75 mg/kg was injected intraperitoneally once a day for 3 days. In group C (combination of treatment group) both 5-Fu (75 mg/kg) and verapamil(25 mg/kg) were administered simultaneously as in A and B. In group D (simple verapamil group) only 6 ml of verapamil (25 mg/kg)was administered as above.Results Compared with groups A, B and D, The volume of cancer and the contents of liver cancer DNA and protein were significantlyreduced. The rates of inhibiting cancer (89.9% in group C and 35.4% in group B) were significantly increased in group C. Group C hadsignificantly long survival time compared to groups A, B and D ( P < 0.05) . By light microscopy, a number of focal necroses were foundin cancer tissue in group C.Conclusion Calcium channel blockers can enhance the antineoplastic effect of 5-Fu intraperitoneal chemotherapy to liver cancer ; Theuse of verapamil can not increase the toxicity of 5-Fu. 展开更多
关键词 calcium channel blockers VERAPAMIL 5-FLUOROURACIL HEPATOCARCINOMA intraperitoneal chemotherapy
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Mitoxantrone Ethylcellulose Microspheres for Liver Arte-rial Embolization
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作者 张志荣 王丹 +1 位作者 廖方义 廖工铁 《Journal of Chinese Pharmaceutical Sciences》 CAS 1996年第4期200-206,共7页
Herein,the orthogonal test was used to optimize the preparation conditions and technique of mitoxantrone ethylcellulose microsphere fDHAQ-EC-MS)for liver arterial embolization.The dynamic dialysis method was used to s... Herein,the orthogonal test was used to optimize the preparation conditions and technique of mitoxantrone ethylcellulose microsphere fDHAQ-EC-MS)for liver arterial embolization.The dynamic dialysis method was used to study the drug release characteristics ofthe DRAQ-EC-MS.The suspension of DHAQ-EC-MS for clinical liver arterial embolization was prepared.The results show that the DHAQ-EC-MS is regular in morphology with a mean diameter of 110.24 ± 38.19μm and 86.5% of them within the range of 40-150μm,The drug loading is 12.5% and the embedding ratio is 55.6%. The release characteristics were in accordance with the single exponential model.The drug release equation is log(Y∞-Y)=-0.116t-1.198 × 10 ̄(-3)(r=0.9992,t(50)=2.6h).The suspension is ofstable physical and chemical properties and is suitable for clinical use. 展开更多
关键词 Mitoxantrone Ethylcellulose microsphere Liver arterial embolization
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