目的探讨治疗性绷带式角膜接触镜在重症泪液蒸发过强型干眼症中的应用价值。方法选取2016年1月—2017年4月重症泪液蒸发过强型干眼症患者54例,随机分为观察组(27例)和对照组(27例),观察组给予人工泪液联合治疗性绷带式角膜接触镜治疗,...目的探讨治疗性绷带式角膜接触镜在重症泪液蒸发过强型干眼症中的应用价值。方法选取2016年1月—2017年4月重症泪液蒸发过强型干眼症患者54例,随机分为观察组(27例)和对照组(27例),观察组给予人工泪液联合治疗性绷带式角膜接触镜治疗,对照组仅给予人工泪液治疗。连续治疗1个月后比较两组自觉症状评分、泪液分泌试验(SⅠt,SⅡt)情况、泪膜破裂时间(Break Up Time,BUT)以及泪液蕨样变试验(Tear Ferning Test,TFT)情况。结果治疗后,两组患者的自觉症状评分均下降,且观察组低于对照组,差异有统计学意义(P<0.05);两组SⅠt、SⅡt以及BUT指标水平均改善,且观察组改善效果更优,差异有统计学意义(P<0.05);观察组TFT指标检测水平优于对照组,差异有统计学意义(P<0.05)。结论治疗性绷带式角膜接触镜在重症泪眼蒸发过强型干眼症患者的治疗中效果确切,能够显著改善其自觉症状评分以及SⅠt、BUT和TFT等指标。展开更多
Objective To provide a more effective microsurgical treatment for obstructive lymphedema.Methods Sixty models of rabbits with lymphedema in right hindlimb were devided into three groups: 20 for fascial flap transplant...Objective To provide a more effective microsurgical treatment for obstructive lymphedema.Methods Sixty models of rabbits with lymphedema in right hindlimb were devided into three groups: 20 for fascial flap transplantation (group A), 20 for no treatment (group B) and 20 for anastomosis of lymph vessels and vein (group C) as control. For group A, the posterior branch of medial vein in the normal hindlimb was cut down together with the fascial strip (about 3 cm wide) around it and concomitant lymph vessels, then transferred through the block region of the affected limb. The two broken tips of the vein were anastomosed respectively to normal veins beside the block region. Subcutaneous tissue and skin were sutured at last. For group B, no treatment was carried out. But traditional anastomosis of lymph vessels and vein was used for group C. Postoperative variation of volume was observed and lymphoscintigraphy was made. Results The volume curve of the affected limb in group A kept declining after 2 weeks and nearing to that of the normal hindlimb in group B but away from that of the affected limb in group B. The curve of donor limb in group A was similar to that of the normal limb of group B, which meant no secondary lymphedema occurred in donor limb. The volume of the affected limb of group A had significant difference to that of group C at postoperative 24 weeks, which meant the effect of group A was better than C. The lymphatic drainage of the affected limb of group A was obviously better than B and C in lymphoscintigraphic image. Deposit of nuclein was lessened. Conclusion It was verified that the transplantation of vein-lymph vessels-fatty fascial flap had following advantages: decreased technical difficulty, better long-term effect, almost no chronic lymphedema occurred in donor site, extensive adaptation.展开更多
文摘目的探讨治疗性绷带式角膜接触镜在重症泪液蒸发过强型干眼症中的应用价值。方法选取2016年1月—2017年4月重症泪液蒸发过强型干眼症患者54例,随机分为观察组(27例)和对照组(27例),观察组给予人工泪液联合治疗性绷带式角膜接触镜治疗,对照组仅给予人工泪液治疗。连续治疗1个月后比较两组自觉症状评分、泪液分泌试验(SⅠt,SⅡt)情况、泪膜破裂时间(Break Up Time,BUT)以及泪液蕨样变试验(Tear Ferning Test,TFT)情况。结果治疗后,两组患者的自觉症状评分均下降,且观察组低于对照组,差异有统计学意义(P<0.05);两组SⅠt、SⅡt以及BUT指标水平均改善,且观察组改善效果更优,差异有统计学意义(P<0.05);观察组TFT指标检测水平优于对照组,差异有统计学意义(P<0.05)。结论治疗性绷带式角膜接触镜在重症泪眼蒸发过强型干眼症患者的治疗中效果确切,能够显著改善其自觉症状评分以及SⅠt、BUT和TFT等指标。
基金the Found for Youth from Shanghai Educational Committee(2000QN83)
文摘Objective To provide a more effective microsurgical treatment for obstructive lymphedema.Methods Sixty models of rabbits with lymphedema in right hindlimb were devided into three groups: 20 for fascial flap transplantation (group A), 20 for no treatment (group B) and 20 for anastomosis of lymph vessels and vein (group C) as control. For group A, the posterior branch of medial vein in the normal hindlimb was cut down together with the fascial strip (about 3 cm wide) around it and concomitant lymph vessels, then transferred through the block region of the affected limb. The two broken tips of the vein were anastomosed respectively to normal veins beside the block region. Subcutaneous tissue and skin were sutured at last. For group B, no treatment was carried out. But traditional anastomosis of lymph vessels and vein was used for group C. Postoperative variation of volume was observed and lymphoscintigraphy was made. Results The volume curve of the affected limb in group A kept declining after 2 weeks and nearing to that of the normal hindlimb in group B but away from that of the affected limb in group B. The curve of donor limb in group A was similar to that of the normal limb of group B, which meant no secondary lymphedema occurred in donor limb. The volume of the affected limb of group A had significant difference to that of group C at postoperative 24 weeks, which meant the effect of group A was better than C. The lymphatic drainage of the affected limb of group A was obviously better than B and C in lymphoscintigraphic image. Deposit of nuclein was lessened. Conclusion It was verified that the transplantation of vein-lymph vessels-fatty fascial flap had following advantages: decreased technical difficulty, better long-term effect, almost no chronic lymphedema occurred in donor site, extensive adaptation.
