Objective: To evaluate the effect of intraperitoneal chemotherapy or in combination with other therapies in patients with advanced primary liver cancer. Methods: 72 patients with advanced primary liver cancer with n...Objective: To evaluate the effect of intraperitoneal chemotherapy or in combination with other therapies in patients with advanced primary liver cancer. Methods: 72 patients with advanced primary liver cancer with no indication for surgery received intraperitoneal chemotherapy in combination with other therapies including transcatheter arterial chemoembolization (TACE), radiofrequency catheter ablation (RFA), percutaneous ethanol injection therapy (PELT) and radiotherapy. Of them, 29 cases were complicated with hilar or retroperitoneal multiple lymph node metastases, 14 with portal vein embolus, 15 with intrapedtoneal and diaphragmatic metastases, 6 with chylous ascites, one with cancerous ascites, and 7 with suspected cancerous ascites (referring to large amounts of ascites without hypoproteinemia while exfoliative cytology of the ascites was positive). The mean maximum tumor size was 8.2 cm in diameter. Liver function at the initial treatment was Child A in 53 cases, and Child B in 19 cases. I ntrapedtoneal chemotherapy was performed in all these patients. The intraperitoneal chemotherapy protocols included: 5-FU 0.5-0.75 g/d for 10-15 consecutive days, with a total dosage of 5-12.5 g, and at the last day of chemotherapy 10 mg mitomycin (MMC) or 100 mg carboplatin was injected. For 7 cases of cholangiocarcinoma, Gemzar 800-1000 mg was administered additionally. A majority of all these patients received another one or two therapy methods followed by intraperitoneal chemotherapy. TACE was performed in the patients with multiple tumors or nodule more than 5 cm in diameter in the liver, RFA or PElT with nodule fewer than 4 in number and 5 cm or less than 5 cm in diameter and radiotherapy, only for metastases, with metastatic lymph nodes, localized metastasis within the abdominal cavity or portal vein embolus. Interval time between two methods was one month or so. Two months after the sequential therapy, repeated treatment would be given if general medical condition and liver function were perfect at that time. Results: The median survival time of the group was 13.97 ± 6.27 months. The 1- and 2-year survival rates were 59.7% and 30.6% respectively. The mean survival time of the patients with liver function Child A was 15.91 ± 5.49 months, and that of the patients with Child B was 8.55 ± 5.09 months. The difference was statistically significant (P 〈 0.05). Conclusion: Intraperitoneal chemotherapy or in combination with other therapies in patients with advanced primary liver cancer with metastases to abdominal cavity is an effective method. It can prolong the survival time and improve life quality for a certain percentage of patients with advanced pnmary liver cancer.展开更多
Background: Trigeminal neuralgia (TN) is a neuropathic pain syndrome. It is the most frequent cranial neuralgia and defined as sudden, usually unilateral and lightning-like, knife-like or burning-like recurrent epi...Background: Trigeminal neuralgia (TN) is a neuropathic pain syndrome. It is the most frequent cranial neuralgia and defined as sudden, usually unilateral and lightning-like, knife-like or burning-like recurrent episodes of pain within the distribution area of one or more divisions of the trigeminal nerve. Here we reported that an 81-year-old woman with TN who complained of severe pain on her right face showed a complete clinical relief after comprehensive therapy containing fire needle, filiform needle and blood-letting therapy. Methods: The patient was applied fire needle combined with filiform needle therapy (3 times / week for 4 months) and three consecutive fire needle combined with blood-letting therapy (3 times / week for one week). Fire needle was inserted into the back points of Du meridian, the first lateral line of bladder meridian, the right spreading area of the trigeminal nerve and the points around the pain radiation site. The filiform needle acupuncture was applied to the points on the right face including Yuyao (EX-HN4), Yangbai (GB14), Toulinqi (GB15), et al; points on the abdomen including Xiawan (RN10), Qihai (RN16), Guanyuan (RN14) and the bilateral points including Tianshu (ST25), Daheng (SP15), Zusanli (ST36), et al. Finally, the three-edged fire needle punctured the points of Yangbai (GB41), Shangguan (GB3), Jiache (ST6) on the right face accompanied by the cupping method on the bleeding points. Results: The patient reported the complete disappearance of pain and could open mouth and eat normally. The face was normal and no triggering pain recurred after one-month follow-up. Conclusions: The fire needle combined with blood-letting therapy can cure the TN and might provide an alternative non-drug therapy for those patients who still suffered from TN after other medical treatments or whom that refused surgical treatment.展开更多
China's emergency laws have emerged as a result of dealing with crises. They comprise laws and regulations, emergency plans, and military regulations, and define three exceptional or emergency states: war, emergency...China's emergency laws have emerged as a result of dealing with crises. They comprise laws and regulations, emergency plans, and military regulations, and define three exceptional or emergency states: war, emergency and emergency response, with the aim of constructing a comprehensive integrated system based on the specialized division of labor. In practice, however, emergency plans take the place of laws and regulations and provide the fundamental normative basis for tackling emergencies, with government and the military playing the dominant role. Developing out of necessity and possessing temporary applicability, China's emergency laws are characterized by authorization and prevention. Integrating emergency law with the socialist legal system with Chinese characteristics, formulating basic law for emergency situations and improving the specific mechanisms of emergency law should be regarded as major steps in its future development.展开更多
The recent development of automatically operating, inexpensive vertical-looking radar (VLR) for entomological purposes has made it practical to carry out routine, automated monitoring of insect aerial migration throug...The recent development of automatically operating, inexpensive vertical-looking radar (VLR) for entomological purposes has made it practical to carry out routine, automated monitoring of insect aerial migration throughout the year. In this paper we investigate whether such radars might have a role in monitoring and forecasting schemes designed to improve the management of the Brown Planthopper (BPH), Nilaparvata lugens, and of associated rice pest species in China. A survey of the literature revealed that these insects typically migrate at altitudes between 300 to 2 000 m above ground level, but calculations based on BPH radar scattering cross-sections indicated that the maximum altitude at which they individually produce signals analysable by current VLRs is only~240 m. We also show that coverage over most of the flight altitudes of BPH could be achieved by building a VLR using a wavelength of 8.8 mm instead of the 3.2 cm of existing VLR, but that such a radar would be expensive to build and to operate. We suggest that a more practical solution would be to use a 3.2 cm VLR as a monitor of the aerial movement of the larger species, from which the migration of rice pests in general might be inferred.展开更多
文摘Objective: To evaluate the effect of intraperitoneal chemotherapy or in combination with other therapies in patients with advanced primary liver cancer. Methods: 72 patients with advanced primary liver cancer with no indication for surgery received intraperitoneal chemotherapy in combination with other therapies including transcatheter arterial chemoembolization (TACE), radiofrequency catheter ablation (RFA), percutaneous ethanol injection therapy (PELT) and radiotherapy. Of them, 29 cases were complicated with hilar or retroperitoneal multiple lymph node metastases, 14 with portal vein embolus, 15 with intrapedtoneal and diaphragmatic metastases, 6 with chylous ascites, one with cancerous ascites, and 7 with suspected cancerous ascites (referring to large amounts of ascites without hypoproteinemia while exfoliative cytology of the ascites was positive). The mean maximum tumor size was 8.2 cm in diameter. Liver function at the initial treatment was Child A in 53 cases, and Child B in 19 cases. I ntrapedtoneal chemotherapy was performed in all these patients. The intraperitoneal chemotherapy protocols included: 5-FU 0.5-0.75 g/d for 10-15 consecutive days, with a total dosage of 5-12.5 g, and at the last day of chemotherapy 10 mg mitomycin (MMC) or 100 mg carboplatin was injected. For 7 cases of cholangiocarcinoma, Gemzar 800-1000 mg was administered additionally. A majority of all these patients received another one or two therapy methods followed by intraperitoneal chemotherapy. TACE was performed in the patients with multiple tumors or nodule more than 5 cm in diameter in the liver, RFA or PElT with nodule fewer than 4 in number and 5 cm or less than 5 cm in diameter and radiotherapy, only for metastases, with metastatic lymph nodes, localized metastasis within the abdominal cavity or portal vein embolus. Interval time between two methods was one month or so. Two months after the sequential therapy, repeated treatment would be given if general medical condition and liver function were perfect at that time. Results: The median survival time of the group was 13.97 ± 6.27 months. The 1- and 2-year survival rates were 59.7% and 30.6% respectively. The mean survival time of the patients with liver function Child A was 15.91 ± 5.49 months, and that of the patients with Child B was 8.55 ± 5.09 months. The difference was statistically significant (P 〈 0.05). Conclusion: Intraperitoneal chemotherapy or in combination with other therapies in patients with advanced primary liver cancer with metastases to abdominal cavity is an effective method. It can prolong the survival time and improve life quality for a certain percentage of patients with advanced pnmary liver cancer.
文摘Background: Trigeminal neuralgia (TN) is a neuropathic pain syndrome. It is the most frequent cranial neuralgia and defined as sudden, usually unilateral and lightning-like, knife-like or burning-like recurrent episodes of pain within the distribution area of one or more divisions of the trigeminal nerve. Here we reported that an 81-year-old woman with TN who complained of severe pain on her right face showed a complete clinical relief after comprehensive therapy containing fire needle, filiform needle and blood-letting therapy. Methods: The patient was applied fire needle combined with filiform needle therapy (3 times / week for 4 months) and three consecutive fire needle combined with blood-letting therapy (3 times / week for one week). Fire needle was inserted into the back points of Du meridian, the first lateral line of bladder meridian, the right spreading area of the trigeminal nerve and the points around the pain radiation site. The filiform needle acupuncture was applied to the points on the right face including Yuyao (EX-HN4), Yangbai (GB14), Toulinqi (GB15), et al; points on the abdomen including Xiawan (RN10), Qihai (RN16), Guanyuan (RN14) and the bilateral points including Tianshu (ST25), Daheng (SP15), Zusanli (ST36), et al. Finally, the three-edged fire needle punctured the points of Yangbai (GB41), Shangguan (GB3), Jiache (ST6) on the right face accompanied by the cupping method on the bleeding points. Results: The patient reported the complete disappearance of pain and could open mouth and eat normally. The face was normal and no triggering pain recurred after one-month follow-up. Conclusions: The fire needle combined with blood-letting therapy can cure the TN and might provide an alternative non-drug therapy for those patients who still suffered from TN after other medical treatments or whom that refused surgical treatment.
文摘China's emergency laws have emerged as a result of dealing with crises. They comprise laws and regulations, emergency plans, and military regulations, and define three exceptional or emergency states: war, emergency and emergency response, with the aim of constructing a comprehensive integrated system based on the specialized division of labor. In practice, however, emergency plans take the place of laws and regulations and provide the fundamental normative basis for tackling emergencies, with government and the military playing the dominant role. Developing out of necessity and possessing temporary applicability, China's emergency laws are characterized by authorization and prevention. Integrating emergency law with the socialist legal system with Chinese characteristics, formulating basic law for emergency situations and improving the specific mechanisms of emergency law should be regarded as major steps in its future development.
文摘The recent development of automatically operating, inexpensive vertical-looking radar (VLR) for entomological purposes has made it practical to carry out routine, automated monitoring of insect aerial migration throughout the year. In this paper we investigate whether such radars might have a role in monitoring and forecasting schemes designed to improve the management of the Brown Planthopper (BPH), Nilaparvata lugens, and of associated rice pest species in China. A survey of the literature revealed that these insects typically migrate at altitudes between 300 to 2 000 m above ground level, but calculations based on BPH radar scattering cross-sections indicated that the maximum altitude at which they individually produce signals analysable by current VLRs is only~240 m. We also show that coverage over most of the flight altitudes of BPH could be achieved by building a VLR using a wavelength of 8.8 mm instead of the 3.2 cm of existing VLR, but that such a radar would be expensive to build and to operate. We suggest that a more practical solution would be to use a 3.2 cm VLR as a monitor of the aerial movement of the larger species, from which the migration of rice pests in general might be inferred.