To introduce the advances of experimental research on acupuncture and moxibustion for treatment of Women's Climacteric Syndrome.The recent years experimental research literature of acupuncture and moxibustion for tre...To introduce the advances of experimental research on acupuncture and moxibustion for treatment of Women's Climacteric Syndrome.The recent years experimental research literature of acupuncture and moxibustion for treatment of Women's Climacteric Syndrome were reviewed.The research literatures on acupuncture treatment were major,focusing on the field of acupuncture and moxibustion regulating hypothalamic-pituitary-gonad axis and nerval-endocritic-immune net.Acupuncture and moxibustion could regulate the endocrine environment of menopausal women.Taking advantage of combination biomedicine with multi-sciences,to improve the acupuncture and moxibustion curative effct and probe the mechanism of menopausal pathology and acupuncture and moxibustion function to Women's Climacteric Syndrome,is the research direction afterward.展开更多
AIM: To correlate the clinical features of treated and untreated patients with irritable bowel syndrome (IBS) to the results of skin prick test (SPT) for food and inhalant allergens. METHODS: We recruited 105 su...AIM: To correlate the clinical features of treated and untreated patients with irritable bowel syndrome (IBS) to the results of skin prick test (SPT) for food and inhalant allergens. METHODS: We recruited 105 subjects to form three different target groups: treated group (n=44) undergoing treatment for IBS, untreated group (n =31) meeting the Rome Ⅱ criteria without treatment for IBS, control group (n = 30) with no IBS symptoms. RESULTS: SPT results were different among the three groups in which SPT was positive in 17 (38.6%) treated patients, in 5 (16.1%) untreated patients and in 1 (3.3%) control (P〈0.01). The number of positive SPTs was greater in the IBS group than in the control group (P〈 0.001). The number of positive food SPTs was higher in the treated IBS group than in the untreated IBS group (P= 0.03). CONCLUSION: Positive food SPT is higher in IBS patients than in controls.展开更多
Budd-Chiari syndrome is a congestive hepatopathy caused by blockage of hepatic veins. This syndrome occurs in 1/100 000 in the general population. Hypercoagulable state could be identified in 75% of the patients; more...Budd-Chiari syndrome is a congestive hepatopathy caused by blockage of hepatic veins. This syndrome occurs in 1/100 000 in the general population. Hypercoagulable state could be identified in 75% of the patients; more than one etiologic factor may play a role in 25% of the patients. Primary myeloproliferative diseases are the leading cause of the disease. Two of the hepatic veins must be blocked for clinically evident disease. Liver congestion and hypoxic damage of hepatocytes eventually result in predominantly centrilobular fibrosis. Doppler ultrasonography of the liver should be the initial diagnostic procedure. Hepatic venography is the reference procedure if required. Additionally liver biopsy may be helpful for differential diagnosis. The prognosis of the chronic form is acceptable compared to other chronic liver diseases.展开更多
This paper discusses the progress of computer integrated processing (CIPS) of coal-preparation and then preserits an intelligence controlled production-process, device-maintenance and production-management system of...This paper discusses the progress of computer integrated processing (CIPS) of coal-preparation and then preserits an intelligence controlled production-process, device-maintenance and production-management system of coal- preparation based on multi-agents (IICMMS-CP). The construction of the IICMMS-CP, the distributed network control system based on live intelligence control stations and the strategy of implementing distributed intelligence control system are studied in order to overcome the disadvantages brought about by the wide use of the PLC system by coaipreparation plants. The software frame, based on a Multi-Agent Intelligence Control and Maintenance Management integrated system, is studied and the implemention methods of IICMMS-CP are discussed. The characteristics of distributed architecture, cooperation and parallel computing meet the needs of integrated control of coal-preparation plants with large-scale spatial production distribution, densely-related processes and complex systems. Its application further improves the reliability and precision of process control, accuracy of fault identification and intelligence of production adjustment, establishes a technical basis for system integration and flexible production. The main function of the system has been tested in a coal-preparation plant to good effect in stabilizing product quality, improving efficiency and reducing consumption.展开更多
Unicentric Castleman's disease of the pancreas is extremely rare, with only six cases described in the worldwide literature. An asymptomatic case of unicentric, hyaline, vascular-type Castleman's disease (UCD) loc...Unicentric Castleman's disease of the pancreas is extremely rare, with only six cases described in the worldwide literature. An asymptomatic case of unicentric, hyaline, vascular-type Castleman's disease (UCD) localized to the tail of bhe pancreas with central calcification imitating a primary neoplasm of the pancreas is presented. This is the first description of endosonographic and endoscopic retrograde pancreatographic findings of pancreatic UCD. Additionally, computed tomography, histological and serologic findings are reported.展开更多
Irritable bowel syndrome (IBS) and chronic pelvic pain (CPP) are both somatoform disorders with a high prevalence within the population in general. The objective was to compare both entities, to find the differenc...Irritable bowel syndrome (IBS) and chronic pelvic pain (CPP) are both somatoform disorders with a high prevalence within the population in general. The objective was to compare both entities, to find the differences and the similarities related to epidemiology and psychosocial aspects like stressful life events, physical and sexual abuse, illness behaviour and comorbidity. The technical literature was reviewed systematically from 1971 to 2006 and compared. According to literature, IBS and CPP seem to be one rather than two different entities with the same Iocalisation of pain. Both syndromes also are similar concerning prevalence, the coexistence of mental and somatoform disorders, the common history of sexual and physical abuse in the past and their health care utilization. It could be shown that there were many similarities between IBS and CPP. Nevertheless both are traded as different clinical pictures as far. Therefore it seems to be reasonable and necessary to generate a common diagnosis algorithm and to bring gynaecologists and gastroenterologists into dialogue.展开更多
Various benign and malignant conditions could cause biliary obstruction. Compression of extrahepatic bile duct (EBD) by right hepatic artery was reported as a right hepatic artery syndrome but all cases were compresse...Various benign and malignant conditions could cause biliary obstruction. Compression of extrahepatic bile duct (EBD) by right hepatic artery was reported as a right hepatic artery syndrome but all cases were compressed EBD from stomach side. Our case compressed from dorsum was not yet reported, so it was thought to be a very rare case. We present here the first case of bile duct obstruction due to the compression of EBD from dorsum by right hepatic artery.展开更多
AIM: To explore the relationship between the level of proinsulin with cardiovascular risk factors and sleep snoring.METHODS: Based on the random stratified sampling principle, 1 193 Chinese residents in Pizhou City, J...AIM: To explore the relationship between the level of proinsulin with cardiovascular risk factors and sleep snoring.METHODS: Based on the random stratified sampling principle, 1 193 Chinese residents in Pizhou City, Jiangsu Province (530 males and 663 females, aged 35-59 years with an average age of 46.69 years) were recruited. Their sleep snoring habits were investigated. Biotin-avidin based double mAbs ELISA was used to detect specific insulin and proinsulin, and a risk factor score was established to evaluate the individuals according to the number of their risk factors.RESULTS: The results of Spearman correlation analysis and covariate ANOVA analysis after age and sex were controlled, indicated that not only the level of proinsulin (r = 0.156, P = 0.000, F= 5.980 P = 0.000), but also cardiovascular risk factors score (r = 0.194, P = 0.000,F= 11.135, P = 0.000) significantly associated with the frequency of sleep snoring, and the significant relationship between true insulin and frequency of sleep snoring was only shown in the covariate ANOVA analysis (F = 2.868,P = 0.022). The result of multivariate stepwise logistic regression after age, sex, body mass index, waist circumference and true insulin were controlled showed that proinsulin (division by interval of quartile) was an independent risk factor for sleep snoring (OR = 1.220,95%CI: 1.085-1.373, P = 0.001).CONCLUSION: The interaction of cardiovascular risk factors clustering, high proinsulin level and sleep breathing disorder may be a syndrome, which has not been recognized in human beings so far.展开更多
Symptomatic hepato-diaphragmatic interposition of a bowel loop or Chilaiditi's syndrome is a peculiar anatomical condition most often found by chance. Its described symptoms range from intermittent, mild abdominal...Symptomatic hepato-diaphragmatic interposition of a bowel loop or Chilaiditi's syndrome is a peculiar anatomical condition most often found by chance. Its described symptoms range from intermittent, mild abdominal pain and dyspepsia to acute intestinal obstruction. We report a case of hepato-diaphragmatic migration of the hepatic flexure of the colon associated to an unusual, heretofore unreported, angina-like pain exclusively evoked by the left lateral decubitus. To maximize the chance of observing anatomical changes in different postures, computed tomography of the chest and abdomen was performed after air insufflation into the colon. While frank herniation into the chest was excluded, the scan showed that the hepatic flexure-with the interposition of the diaphragm-came in contact with the right side of the heart in the left lateral, but not in the supine, decubitus. This finding was reproduced by echocardiography which also showed virtually unaltered hemodynamics after the change of posture. ECG, left and right ventricular global and regional function as well as cardiac injury markers also remained unchanged during the maneuver, indicating that the pain evoked by the latter was unlikely due to myocardial ischemia. This case suggests that Chilaiditi's syndrome should be included among the possible, although rare,causes of unexplained angina-like symptoms.展开更多
Aiming at the surrounding rock control problem of mining and preparation entries in Xingdong mine with large mining depth, and the comprehensive control countermeasures including high pre-stress cable truss system, th...Aiming at the surrounding rock control problem of mining and preparation entries in Xingdong mine with large mining depth, and the comprehensive control countermeasures including high pre-stress cable truss system, this study put forward powerful anchor support system and anchor cable adaption technology to surrounding rock deformation. Furthermore, the control measures possess the supporting performance with ‘‘primary rigid-following flexible-new rigid, and primary resistance-following yield-new resistance'', which suits deep roadway surrounding rock control. The mechanical model of truss anchor supporting roof beams was established, and the inverted arch deflection produced by the cable pre-stress with stress increment effect and roof beam deflection were obtained. And then the system working mechanism was illustrated. Finally, the surrounding rock support parameters were determined by means of comprehensive methods, and put into practice. The results show that surrounding rock deformation realized secondary stability after three months. The roadway sides convergence value was less than 245mm, and roof subsidence was less than 124mm. In addition, there was no expansion and renovation during service period.展开更多
Objective: To analyze the main etiological diagnoses of patients attended at a genetics outpatient clinic of the Association of Parents and Friends of Exceptional Children/APAE in the state of Amazonas, Brazil. Meth...Objective: To analyze the main etiological diagnoses of patients attended at a genetics outpatient clinic of the Association of Parents and Friends of Exceptional Children/APAE in the state of Amazonas, Brazil. Methods: retrospective study of patients seen in the period 2005-2016, with review of medical records. The following data were recorded: sex, origin of referral and etiological diagnosis. Results: 362 patients were attended, 94.7% of them from Manaus, and 5.3% from the interior of the state. The etiological diagnosis was defined in 262 (72.3%) of the sample, of which 254 (70.2%) were of genetic etiology and 8 (2.2%) non-genetic. Of the genetic etiologies, 46 (12.7%) cases were monogenic syndromes, 136 (37.6%) were chromosomal aberrations and 72 (19.9%) had multifactorial causes, however, 100 (27.6%) cases remained unclear. There were several syndromes found, with Down syndrome being the most frequent and correlating significantly with the sex of the patient (male predominance, p 〈 0.05). Conclusions: The study carried out in the APAE/Manaus genetics outpatient clinic allowed the profile of the patients being attended to be traced. It was verified that the majority of the patients were male and that the diagnosis of chromosomal alterations was the most frequent.展开更多
According to the modern theory of human resource management, the condition of buyout mainly depends on two variables of an employee: his interior value of product and exterior work reward. There exist shortages in eva...According to the modern theory of human resource management, the condition of buyout mainly depends on two variables of an employee: his interior value of product and exterior work reward. There exist shortages in evaluating the value of the employees in an enterprise. Consequently, a lot of employees might be laid off. Hence, this paper puts forward a two-stage method for decision-making to carry out a selective plan of buyout, based on the fuzzy synthetic evaluation involing many factors impacting on human resource. Moreover, a positive analysis is also given.展开更多
General as well as the municipal solid waste (MSW) management in Thailand is reviewed in this paper. Topics include the MSW generation, sources, composition and trends. The review, then, moves to sustainable solutio...General as well as the municipal solid waste (MSW) management in Thailand is reviewed in this paper. Topics include the MSW generation, sources, composition and trends. The review, then, moves to sustainable solutions for MSW management and sustainable alternative approaches with an emphasis on an integrated MSW management. Information of waste in Thailand is also given at the beginning of this paper for better understanding of later contents. It is clear that no one single method of MSW disposal can deal with all materials in an environmentally sustainable way. As such, a suitable approach in MSW management should be an integrated approach that could deliver both environmental and economic sustainability. With increasing environmental concerns, the integrated MSW management system has a potential to maximize the useable waste materials as well as produce energy as a by-product. In Thailand, the compositions of waste (86%) are mainly organic waste, paper, plastic, glass and metal. As a result, the waste in Thailand is suitable for an integrated MSW management. Currently, the Thai national waste management policy starts to encourage the local administrations to gather into clusters, to establish central MSW disposal facilities with suitable technologies and reducing the disposal cost based on the amount of MSW generated.展开更多
The utility of public goods vary with the behaviors of stakeholders (players), and it is appropriate to study effective supply and management of public goods with game modeling and analysis. The comparison effect is...The utility of public goods vary with the behaviors of stakeholders (players), and it is appropriate to study effective supply and management of public goods with game modeling and analysis. The comparison effect is the key issue of public good provision both in theoretical analysis and in practice. One major contribution of the paper is the extension of Clarke-Groves mechanism, to achieve which strategic behavior analysis is applied through the analysis and the comparison effect among various stakeholders in different stages is created and highly emphasized. In the first section of this paper, the definition of integrated water resources management (IWRM), the importance of stakeholder participation as well as some models and methods that have been applied are illustrated. Following this, the framework of analysis is elaborated, in which the scenario and aims are shown, and it is claimed that game theory is the main approach, which includes both cooperative games and non-cooperative games. To achieve the aims of the public project, five approaches from game theory are able to cover the entire process of the project, and the fourth approach on interest compensation mechanism is the highlight of the research. After this, the interest compensation mechanism is demonstrated in the model section, and is proved to be an incentive compatible mechanism that makes each stakeholder choose to behave in accordance with the interest of the entire project. The Clarke-Groves mechanism is applied and extended in establishing the model, and the utility change by the comparison among stakeholders (defined as the comparison effect) is involved. In the application section, a water project is analyzed in consideration of various stakeholders, and other possible applications are also indicated.展开更多
The aim of this study is to study the difference of immunologic parameters between severe acute respiratory syndrome (SARS) patients of mild type and severe type. Data including white blood cell (WBC) count, lymph...The aim of this study is to study the difference of immunologic parameters between severe acute respiratory syndrome (SARS) patients of mild type and severe type. Data including white blood cell (WBC) count, lymphocyte count, CD3, CD4 and CD8 T lymphocyte count, levels of C3, C4, ESR (erythrocyte sedimentation rate) and CRP (C-reactive protein) from 1291 patients with SARS in each week from onset of illness were recorded. The clinical progress of each sign was analysed and the difference between mild type and severe type was compared. Lymphocyte count, CD8 T lymphocyte count declined in the first two weeks and recovered from the third week, while CRP and CA- levels rose in the first week and then recovered gradually. Lymphocyte count and CD8 T lymphocyte count of severe cases were much lower than that of mild type (P 〈 0.01), while CRP and CA- levels in severe type were much higher than that of mild type (P 〈 0.01). Lymphocyte count, CD8 T lymphocyte count, CRP and CA- levels are useful signs for the diagnosis of SARS of severe type and are valuable for the evaluation of its severity.展开更多
文摘To introduce the advances of experimental research on acupuncture and moxibustion for treatment of Women's Climacteric Syndrome.The recent years experimental research literature of acupuncture and moxibustion for treatment of Women's Climacteric Syndrome were reviewed.The research literatures on acupuncture treatment were major,focusing on the field of acupuncture and moxibustion regulating hypothalamic-pituitary-gonad axis and nerval-endocritic-immune net.Acupuncture and moxibustion could regulate the endocrine environment of menopausal women.Taking advantage of combination biomedicine with multi-sciences,to improve the acupuncture and moxibustion curative effct and probe the mechanism of menopausal pathology and acupuncture and moxibustion function to Women's Climacteric Syndrome,is the research direction afterward.
基金Supported by a grant from the Korea Society of Neurogastroen-terology and Motility Research Funds (project No. 2003530)
文摘AIM: To correlate the clinical features of treated and untreated patients with irritable bowel syndrome (IBS) to the results of skin prick test (SPT) for food and inhalant allergens. METHODS: We recruited 105 subjects to form three different target groups: treated group (n=44) undergoing treatment for IBS, untreated group (n =31) meeting the Rome Ⅱ criteria without treatment for IBS, control group (n = 30) with no IBS symptoms. RESULTS: SPT results were different among the three groups in which SPT was positive in 17 (38.6%) treated patients, in 5 (16.1%) untreated patients and in 1 (3.3%) control (P〈0.01). The number of positive SPTs was greater in the IBS group than in the control group (P〈 0.001). The number of positive food SPTs was higher in the treated IBS group than in the untreated IBS group (P= 0.03). CONCLUSION: Positive food SPT is higher in IBS patients than in controls.
基金Yusuf Bayraktar, MD, Gastroenterology Department, Hacettepe University School of Medicine, Ankara, Turkey. bayrak@hacettepe.edu.trTelephone: +90-312-3051712 Fax: +90-312-3051490
文摘Budd-Chiari syndrome is a congestive hepatopathy caused by blockage of hepatic veins. This syndrome occurs in 1/100 000 in the general population. Hypercoagulable state could be identified in 75% of the patients; more than one etiologic factor may play a role in 25% of the patients. Primary myeloproliferative diseases are the leading cause of the disease. Two of the hepatic veins must be blocked for clinically evident disease. Liver congestion and hypoxic damage of hepatocytes eventually result in predominantly centrilobular fibrosis. Doppler ultrasonography of the liver should be the initial diagnostic procedure. Hepatic venography is the reference procedure if required. Additionally liver biopsy may be helpful for differential diagnosis. The prognosis of the chronic form is acceptable compared to other chronic liver diseases.
文摘This paper discusses the progress of computer integrated processing (CIPS) of coal-preparation and then preserits an intelligence controlled production-process, device-maintenance and production-management system of coal- preparation based on multi-agents (IICMMS-CP). The construction of the IICMMS-CP, the distributed network control system based on live intelligence control stations and the strategy of implementing distributed intelligence control system are studied in order to overcome the disadvantages brought about by the wide use of the PLC system by coaipreparation plants. The software frame, based on a Multi-Agent Intelligence Control and Maintenance Management integrated system, is studied and the implemention methods of IICMMS-CP are discussed. The characteristics of distributed architecture, cooperation and parallel computing meet the needs of integrated control of coal-preparation plants with large-scale spatial production distribution, densely-related processes and complex systems. Its application further improves the reliability and precision of process control, accuracy of fault identification and intelligence of production adjustment, establishes a technical basis for system integration and flexible production. The main function of the system has been tested in a coal-preparation plant to good effect in stabilizing product quality, improving efficiency and reducing consumption.
文摘Unicentric Castleman's disease of the pancreas is extremely rare, with only six cases described in the worldwide literature. An asymptomatic case of unicentric, hyaline, vascular-type Castleman's disease (UCD) localized to the tail of bhe pancreas with central calcification imitating a primary neoplasm of the pancreas is presented. This is the first description of endosonographic and endoscopic retrograde pancreatographic findings of pancreatic UCD. Additionally, computed tomography, histological and serologic findings are reported.
文摘Irritable bowel syndrome (IBS) and chronic pelvic pain (CPP) are both somatoform disorders with a high prevalence within the population in general. The objective was to compare both entities, to find the differences and the similarities related to epidemiology and psychosocial aspects like stressful life events, physical and sexual abuse, illness behaviour and comorbidity. The technical literature was reviewed systematically from 1971 to 2006 and compared. According to literature, IBS and CPP seem to be one rather than two different entities with the same Iocalisation of pain. Both syndromes also are similar concerning prevalence, the coexistence of mental and somatoform disorders, the common history of sexual and physical abuse in the past and their health care utilization. It could be shown that there were many similarities between IBS and CPP. Nevertheless both are traded as different clinical pictures as far. Therefore it seems to be reasonable and necessary to generate a common diagnosis algorithm and to bring gynaecologists and gastroenterologists into dialogue.
文摘Various benign and malignant conditions could cause biliary obstruction. Compression of extrahepatic bile duct (EBD) by right hepatic artery was reported as a right hepatic artery syndrome but all cases were compressed EBD from stomach side. Our case compressed from dorsum was not yet reported, so it was thought to be a very rare case. We present here the first case of bile duct obstruction due to the compression of EBD from dorsum by right hepatic artery.
基金Supported by the National Natural Science Foundation of China,No. 30400173
文摘AIM: To explore the relationship between the level of proinsulin with cardiovascular risk factors and sleep snoring.METHODS: Based on the random stratified sampling principle, 1 193 Chinese residents in Pizhou City, Jiangsu Province (530 males and 663 females, aged 35-59 years with an average age of 46.69 years) were recruited. Their sleep snoring habits were investigated. Biotin-avidin based double mAbs ELISA was used to detect specific insulin and proinsulin, and a risk factor score was established to evaluate the individuals according to the number of their risk factors.RESULTS: The results of Spearman correlation analysis and covariate ANOVA analysis after age and sex were controlled, indicated that not only the level of proinsulin (r = 0.156, P = 0.000, F= 5.980 P = 0.000), but also cardiovascular risk factors score (r = 0.194, P = 0.000,F= 11.135, P = 0.000) significantly associated with the frequency of sleep snoring, and the significant relationship between true insulin and frequency of sleep snoring was only shown in the covariate ANOVA analysis (F = 2.868,P = 0.022). The result of multivariate stepwise logistic regression after age, sex, body mass index, waist circumference and true insulin were controlled showed that proinsulin (division by interval of quartile) was an independent risk factor for sleep snoring (OR = 1.220,95%CI: 1.085-1.373, P = 0.001).CONCLUSION: The interaction of cardiovascular risk factors clustering, high proinsulin level and sleep breathing disorder may be a syndrome, which has not been recognized in human beings so far.
文摘Symptomatic hepato-diaphragmatic interposition of a bowel loop or Chilaiditi's syndrome is a peculiar anatomical condition most often found by chance. Its described symptoms range from intermittent, mild abdominal pain and dyspepsia to acute intestinal obstruction. We report a case of hepato-diaphragmatic migration of the hepatic flexure of the colon associated to an unusual, heretofore unreported, angina-like pain exclusively evoked by the left lateral decubitus. To maximize the chance of observing anatomical changes in different postures, computed tomography of the chest and abdomen was performed after air insufflation into the colon. While frank herniation into the chest was excluded, the scan showed that the hepatic flexure-with the interposition of the diaphragm-came in contact with the right side of the heart in the left lateral, but not in the supine, decubitus. This finding was reproduced by echocardiography which also showed virtually unaltered hemodynamics after the change of posture. ECG, left and right ventricular global and regional function as well as cardiac injury markers also remained unchanged during the maneuver, indicating that the pain evoked by the latter was unlikely due to myocardial ischemia. This case suggests that Chilaiditi's syndrome should be included among the possible, although rare,causes of unexplained angina-like symptoms.
基金provided by the National Natural Science Foundation of China(No.51234005)National Basic Research Program of China under Grant(No.2010CB226802)Fundamental Research Funds for the Central Universities(No.2010QZ06)
文摘Aiming at the surrounding rock control problem of mining and preparation entries in Xingdong mine with large mining depth, and the comprehensive control countermeasures including high pre-stress cable truss system, this study put forward powerful anchor support system and anchor cable adaption technology to surrounding rock deformation. Furthermore, the control measures possess the supporting performance with ‘‘primary rigid-following flexible-new rigid, and primary resistance-following yield-new resistance'', which suits deep roadway surrounding rock control. The mechanical model of truss anchor supporting roof beams was established, and the inverted arch deflection produced by the cable pre-stress with stress increment effect and roof beam deflection were obtained. And then the system working mechanism was illustrated. Finally, the surrounding rock support parameters were determined by means of comprehensive methods, and put into practice. The results show that surrounding rock deformation realized secondary stability after three months. The roadway sides convergence value was less than 245mm, and roof subsidence was less than 124mm. In addition, there was no expansion and renovation during service period.
文摘Objective: To analyze the main etiological diagnoses of patients attended at a genetics outpatient clinic of the Association of Parents and Friends of Exceptional Children/APAE in the state of Amazonas, Brazil. Methods: retrospective study of patients seen in the period 2005-2016, with review of medical records. The following data were recorded: sex, origin of referral and etiological diagnosis. Results: 362 patients were attended, 94.7% of them from Manaus, and 5.3% from the interior of the state. The etiological diagnosis was defined in 262 (72.3%) of the sample, of which 254 (70.2%) were of genetic etiology and 8 (2.2%) non-genetic. Of the genetic etiologies, 46 (12.7%) cases were monogenic syndromes, 136 (37.6%) were chromosomal aberrations and 72 (19.9%) had multifactorial causes, however, 100 (27.6%) cases remained unclear. There were several syndromes found, with Down syndrome being the most frequent and correlating significantly with the sex of the patient (male predominance, p 〈 0.05). Conclusions: The study carried out in the APAE/Manaus genetics outpatient clinic allowed the profile of the patients being attended to be traced. It was verified that the majority of the patients were male and that the diagnosis of chromosomal alterations was the most frequent.
文摘According to the modern theory of human resource management, the condition of buyout mainly depends on two variables of an employee: his interior value of product and exterior work reward. There exist shortages in evaluating the value of the employees in an enterprise. Consequently, a lot of employees might be laid off. Hence, this paper puts forward a two-stage method for decision-making to carry out a selective plan of buyout, based on the fuzzy synthetic evaluation involing many factors impacting on human resource. Moreover, a positive analysis is also given.
文摘General as well as the municipal solid waste (MSW) management in Thailand is reviewed in this paper. Topics include the MSW generation, sources, composition and trends. The review, then, moves to sustainable solutions for MSW management and sustainable alternative approaches with an emphasis on an integrated MSW management. Information of waste in Thailand is also given at the beginning of this paper for better understanding of later contents. It is clear that no one single method of MSW disposal can deal with all materials in an environmentally sustainable way. As such, a suitable approach in MSW management should be an integrated approach that could deliver both environmental and economic sustainability. With increasing environmental concerns, the integrated MSW management system has a potential to maximize the useable waste materials as well as produce energy as a by-product. In Thailand, the compositions of waste (86%) are mainly organic waste, paper, plastic, glass and metal. As a result, the waste in Thailand is suitable for an integrated MSW management. Currently, the Thai national waste management policy starts to encourage the local administrations to gather into clusters, to establish central MSW disposal facilities with suitable technologies and reducing the disposal cost based on the amount of MSW generated.
文摘The utility of public goods vary with the behaviors of stakeholders (players), and it is appropriate to study effective supply and management of public goods with game modeling and analysis. The comparison effect is the key issue of public good provision both in theoretical analysis and in practice. One major contribution of the paper is the extension of Clarke-Groves mechanism, to achieve which strategic behavior analysis is applied through the analysis and the comparison effect among various stakeholders in different stages is created and highly emphasized. In the first section of this paper, the definition of integrated water resources management (IWRM), the importance of stakeholder participation as well as some models and methods that have been applied are illustrated. Following this, the framework of analysis is elaborated, in which the scenario and aims are shown, and it is claimed that game theory is the main approach, which includes both cooperative games and non-cooperative games. To achieve the aims of the public project, five approaches from game theory are able to cover the entire process of the project, and the fourth approach on interest compensation mechanism is the highlight of the research. After this, the interest compensation mechanism is demonstrated in the model section, and is proved to be an incentive compatible mechanism that makes each stakeholder choose to behave in accordance with the interest of the entire project. The Clarke-Groves mechanism is applied and extended in establishing the model, and the utility change by the comparison among stakeholders (defined as the comparison effect) is involved. In the application section, a water project is analyzed in consideration of various stakeholders, and other possible applications are also indicated.
文摘The aim of this study is to study the difference of immunologic parameters between severe acute respiratory syndrome (SARS) patients of mild type and severe type. Data including white blood cell (WBC) count, lymphocyte count, CD3, CD4 and CD8 T lymphocyte count, levels of C3, C4, ESR (erythrocyte sedimentation rate) and CRP (C-reactive protein) from 1291 patients with SARS in each week from onset of illness were recorded. The clinical progress of each sign was analysed and the difference between mild type and severe type was compared. Lymphocyte count, CD8 T lymphocyte count declined in the first two weeks and recovered from the third week, while CRP and CA- levels rose in the first week and then recovered gradually. Lymphocyte count and CD8 T lymphocyte count of severe cases were much lower than that of mild type (P 〈 0.01), while CRP and CA- levels in severe type were much higher than that of mild type (P 〈 0.01). Lymphocyte count, CD8 T lymphocyte count, CRP and CA- levels are useful signs for the diagnosis of SARS of severe type and are valuable for the evaluation of its severity.