To explore the points selection pattern of acupuncture for sleep apnea syndromes by data mining technique. Methods: Clinical literature about acupuncture therapy for sleep apnea syndromes was derived from China Natio...To explore the points selection pattern of acupuncture for sleep apnea syndromes by data mining technique. Methods: Clinical literature about acupuncture therapy for sleep apnea syndromes was derived from China National Knowledge Infrastructure (CNKI), Wanfang Academic Journal Full-text Database (Wanfang), Chongqing VIP Database (CQVIP), PubMed and Science Direct between the time that databases were created and March 25th,2017. Relevant excel database was established and descriptive studies and association rules were analyzed. Results: The most frequently used point was Lianquan (CV 23) and the most frequently used meridian was the Stomach Meridian. The analysis of association rules showed that the clinical choice of acupuncture points was highly correlated, among which the combination of the highest degree of confidence and the highest degree of support was Shenmen (HT 7) and Sishencong (EX-HN 1); Lieque (LU 7), lianquan (CV 23) and Zhaohai (KI 6). Conclusion: Acupuncture treatment of sleep apnea syndromes has specific selection rules of points, providing certain references for clinical and scientific research.展开更多
OBJECTIVE:Because herbal compatibility is one of the most important reasons why Traditional Chinese Medcine(TCM) formulas are effective for acquired immunodeficiency syndrome(AIDS),our study aimed to determine the com...OBJECTIVE:Because herbal compatibility is one of the most important reasons why Traditional Chinese Medcine(TCM) formulas are effective for acquired immunodeficiency syndrome(AIDS),our study aimed to determine the compatibility of herbs based on published AIDS clinical research in Chinese periodicals.To achieve this aim,we designed a new data-mining algorithm according to TCM data characteristics.METHODS:We found 25 clinical AIDS studies,all using Chinese herbs for treatment,in the Traditional Chinese Medicine Database System,and information on diagnosis and treatment was extracted.To find out herbal compatibility,especially the formulae for herbal combinations,we proposed an improved association rule algorithm based on the frequency of combinations.In this algorithm,all the compatibility relationships were displayed in a tree structure,by which the relationship between formulas and their derivation could be clearly inferred.RESULTS:Data analysis showed that approximately 100 herbs have been used for treating AIDS.Based on the whole herb compatibility tree,we calculated a basic formula for AIDS:Huang Qi combined with Ren Shen,Fu Ling,Bai Zhu,Bai Zhu,Dang Gui,and Bai Shao.This formula,deriving from most of clinical prescriptions,and was chosed by most of clinicians for AIDS treatment.From data mining we found that Qi replenishment and detoxification were the main treatment principles,which coincided with the AIDS pathological mechanism in which immune function is destroyed by human immunodeficiency virus(HIV).CONCLUSIONS:Our data-mining results suggest that the core TCM treatment of AIDS is replenishing Qi and detoxification,by which AIDS patients' immune system may be enhanced.Compatibility of Huang Qi with some frequently-used herbs have shown real efficacy in clinical practice,which warrants pharmacological research in the future.展开更多
Objective:To analyze the meridian and acupoint-selection patterns in acupuncture-moxibustion treatment of polycystic ovarian syndrome (PCOS) by data mining technique,for exploring acupoints that could be effective for...Objective:To analyze the meridian and acupoint-selection patterns in acupuncture-moxibustion treatment of polycystic ovarian syndrome (PCOS) by data mining technique,for exploring acupoints that could be effective for PCOS and providing suggestion and reference in selecting acupoints for the acupuncture-moxibustion treatment of PCOS.Methods:Literatures related to the acupuncture-moxibustion treatment of PCOS published before April 2018 were collected.By a self-made data mining program developed using Microsoft Excel 2007,a database of acupuncture-moxibustion treatment of PCOS was then established.The correlation analysis was performed for the frequency of use of acupoints and acupoint groups.Cluster analysis was also conducted.Results:A total of 92 articles were recruited finally.Sanyinjiao (SP 6),Conception Vessel and chest-abdomen region ranked the top on the list of the most frequently used acupoints,meridians and regions,respectively.Correlation analysis showed that the acupoint group with the highest confidence was Sanyinjiao (SP 6) and Zusanli (ST 36),and the group with the highest support was Sanyinjiao (SP 6) and Guanyuan (CV 4).Cluster analysis revealed five effective clusters:Guanyuan (CV 4) and Sanyinjiao (SP 6);Zhongwan (CV 12) and Tianshu (ST 25);Zhongji (CV 3),Zusanli (ST 36) and Qihai (CV 6);Xuehai (SP 10),Shenshu (BL 23),Taichong (LR 3) and Guilai (ST 29);Ganshu (BL 18),Taixi (KI 3),Yinlingquan (SP 9) and Pishu (BL 20).Conclusion:According to the confidence and support report,Sanyinjiao (SP 6) and Zusanli (ST 36) or Sanyinjiao (SP 6) and Guanyuan (CV 4) are recommended in acupuncture-moxibustion treatment of PCOS,with adjunct points selected for different patterns,e.g.Zhongwan (CV 12) and Tianshu (ST 25) for tonifying spleen and expelling dampness;Zhongji (CV 3) and Qihai (CV 6) for supplementing qi and cultivating blood;Xuehai (SP 10),Shenshu (BL 23),Taichong (LR 3) and Guilai (ST 29) for tonifying kidney and dissolving stasis;Ganshu (BL 18),Taixi (KI 3),Yinlingquan (SP 9) and Pishu (BL 20) for tonifying kidney and spleen and regulating liver.展开更多
基金supported by Hunan Provincial Innovation Foundation for Postgraduate,No.CX2017B427~~
文摘To explore the points selection pattern of acupuncture for sleep apnea syndromes by data mining technique. Methods: Clinical literature about acupuncture therapy for sleep apnea syndromes was derived from China National Knowledge Infrastructure (CNKI), Wanfang Academic Journal Full-text Database (Wanfang), Chongqing VIP Database (CQVIP), PubMed and Science Direct between the time that databases were created and March 25th,2017. Relevant excel database was established and descriptive studies and association rules were analyzed. Results: The most frequently used point was Lianquan (CV 23) and the most frequently used meridian was the Stomach Meridian. The analysis of association rules showed that the clinical choice of acupuncture points was highly correlated, among which the combination of the highest degree of confidence and the highest degree of support was Shenmen (HT 7) and Sishencong (EX-HN 1); Lieque (LU 7), lianquan (CV 23) and Zhaohai (KI 6). Conclusion: Acupuncture treatment of sleep apnea syndromes has specific selection rules of points, providing certain references for clinical and scientific research.
基金Supported by National 863 Project-High Performance Computer and Grid Service Environment-Traditional Chinese Medicine Scientific Data Grid Service Applications (2006AA01A122)
文摘OBJECTIVE:Because herbal compatibility is one of the most important reasons why Traditional Chinese Medcine(TCM) formulas are effective for acquired immunodeficiency syndrome(AIDS),our study aimed to determine the compatibility of herbs based on published AIDS clinical research in Chinese periodicals.To achieve this aim,we designed a new data-mining algorithm according to TCM data characteristics.METHODS:We found 25 clinical AIDS studies,all using Chinese herbs for treatment,in the Traditional Chinese Medicine Database System,and information on diagnosis and treatment was extracted.To find out herbal compatibility,especially the formulae for herbal combinations,we proposed an improved association rule algorithm based on the frequency of combinations.In this algorithm,all the compatibility relationships were displayed in a tree structure,by which the relationship between formulas and their derivation could be clearly inferred.RESULTS:Data analysis showed that approximately 100 herbs have been used for treating AIDS.Based on the whole herb compatibility tree,we calculated a basic formula for AIDS:Huang Qi combined with Ren Shen,Fu Ling,Bai Zhu,Bai Zhu,Dang Gui,and Bai Shao.This formula,deriving from most of clinical prescriptions,and was chosed by most of clinicians for AIDS treatment.From data mining we found that Qi replenishment and detoxification were the main treatment principles,which coincided with the AIDS pathological mechanism in which immune function is destroyed by human immunodeficiency virus(HIV).CONCLUSIONS:Our data-mining results suggest that the core TCM treatment of AIDS is replenishing Qi and detoxification,by which AIDS patients' immune system may be enhanced.Compatibility of Huang Qi with some frequently-used herbs have shown real efficacy in clinical practice,which warrants pharmacological research in the future.
基金the Project of Shanghai Municipal Commission of Health and Family Planning(上海市卫生和计划生育委员会科研课题,201840307)The Research Project of Autonomous Selection of China Academy of Traditional Chinese Medicine(中国中医科学院自主选题研究项目,ZZKF08002)Shanghai Academic Community of Leading Talents in Chinese Medicine.
文摘Objective:To analyze the meridian and acupoint-selection patterns in acupuncture-moxibustion treatment of polycystic ovarian syndrome (PCOS) by data mining technique,for exploring acupoints that could be effective for PCOS and providing suggestion and reference in selecting acupoints for the acupuncture-moxibustion treatment of PCOS.Methods:Literatures related to the acupuncture-moxibustion treatment of PCOS published before April 2018 were collected.By a self-made data mining program developed using Microsoft Excel 2007,a database of acupuncture-moxibustion treatment of PCOS was then established.The correlation analysis was performed for the frequency of use of acupoints and acupoint groups.Cluster analysis was also conducted.Results:A total of 92 articles were recruited finally.Sanyinjiao (SP 6),Conception Vessel and chest-abdomen region ranked the top on the list of the most frequently used acupoints,meridians and regions,respectively.Correlation analysis showed that the acupoint group with the highest confidence was Sanyinjiao (SP 6) and Zusanli (ST 36),and the group with the highest support was Sanyinjiao (SP 6) and Guanyuan (CV 4).Cluster analysis revealed five effective clusters:Guanyuan (CV 4) and Sanyinjiao (SP 6);Zhongwan (CV 12) and Tianshu (ST 25);Zhongji (CV 3),Zusanli (ST 36) and Qihai (CV 6);Xuehai (SP 10),Shenshu (BL 23),Taichong (LR 3) and Guilai (ST 29);Ganshu (BL 18),Taixi (KI 3),Yinlingquan (SP 9) and Pishu (BL 20).Conclusion:According to the confidence and support report,Sanyinjiao (SP 6) and Zusanli (ST 36) or Sanyinjiao (SP 6) and Guanyuan (CV 4) are recommended in acupuncture-moxibustion treatment of PCOS,with adjunct points selected for different patterns,e.g.Zhongwan (CV 12) and Tianshu (ST 25) for tonifying spleen and expelling dampness;Zhongji (CV 3) and Qihai (CV 6) for supplementing qi and cultivating blood;Xuehai (SP 10),Shenshu (BL 23),Taichong (LR 3) and Guilai (ST 29) for tonifying kidney and dissolving stasis;Ganshu (BL 18),Taixi (KI 3),Yinlingquan (SP 9) and Pishu (BL 20) for tonifying kidney and spleen and regulating liver.