Objective: To observe the risk factors of thrombosis in patients with obstructive sleep apnea hypopnea syndrome (OSAHS).Methods: From February 2001 to April 2003, 24 patients with moderate and severe OSAHS (OSAHS grou...Objective: To observe the risk factors of thrombosis in patients with obstructive sleep apnea hypopnea syndrome (OSAHS).Methods: From February 2001 to April 2003, 24 patients with moderate and severe OSAHS (OSAHS group) and 19 healthy adults (control group) were recruited. Their blood samples were drawn at 6∶00 and 16∶00 respectively for testing hemocrit, platelet aggregation (PAG), whole blood viscosity (WBV), prothrombin time (PT), activated partial thromboplastin time (APTT), plasma fibrinogen (Fng) and endothelin (ET).Results: There was a significantly higher hemocrit, WBV, Fng and ET as well as a significant shortening of PT and APTT at 6∶00 than that at 16∶00 in OSAHS group. However, there was no significant difference in all testing items between 6∶00 and 16∶00 in control group. The hemocrit, WBV, PAG, plasma Fng and ET were significantly higher, and PT and APTT were obviously shorter at 6∶00 in OSAHS group than those at 6∶00 in control group. A higher hemocrit, PAG, plasma Fng and ET, a longer PT and APTT were observed at 16∶00 in OSAHS group, compared with those at 16∶00 in control group.Conclusion: In OSAHS patients there were striking risk factors of thrombosis, which is more remarkable in the early morning than in the afternoon.展开更多
Objective This study aimed to assess the protective value of adiponectin(APN)in pancreatic islet injury induced by chronic intermittent hypoxia(CIH).Methods Sixty rats were randomly divided into three groups:normal co...Objective This study aimed to assess the protective value of adiponectin(APN)in pancreatic islet injury induced by chronic intermittent hypoxia(CIH).Methods Sixty rats were randomly divided into three groups:normal control(NC)group,CIH group,and CIH with APN supplement(CIH+APN)group.After 5 weeks of CIH exposure,we conducted oral glucose tolerance tests(OGTT)and insulin released test(IRT),examined and compared the adenosine triphosphate(ATP)levels,mitochondrial membrane potential(MMP)levels,reactive oxygen species(ROS)levels,enzymes gene expression levels of Ant1,Cs,Hmox1,and Cox4 i1 which represented mitochondrial tricarboxylic acid cycle function,the protein and gene expression levels of DRP1,FIS1,MFN1,and OPA1 which represented mitochondrial fusion and division,and the protein expression levels of BAX,BCL-2,cleaved Caspase-3,and cleaved PARP which represented mitochondrial associated apoptosis pathway of pancreatic islet.Results OGTT and IRT showed blood glucose and insulin levels had no differences among the NC,CIH and CIH+APN groups(both P>0.05)at 0 min,20 min,30 min,60 min,120 min.However,we found that compared to NC group,CIH increased the ROS level,reduced ATP level and MMP level.The islets of CIH exposed rats showed reduced gene expression levels of Ant1,Cs,Hmox1,and Cox4 i1,decreased protein and gene expression levels of MFN1 and OPA1,increased protein and gene expression levels of DRP1 and FIS1,increased protein expression levels of cleaved Caspase-3 and cleaved PARP,with lower ratio of BCL-2/BAX at protein expression level.All the differences among three groups were statistically significant.APN treated CIH rats showed mitigated changes in the above measurements associated with islet injuries.Conclusion APN may ameliorate the pancreatic islet injury induced by CIH via inhibiting the imbalance in mitochondrial fusion and division.展开更多
Objective: To study the diagnostic method, surgical management and complications of the tracheal malignant tumor, as well as the characteristics of plasmocytoma. Methods: One patient with tracheal plasmocytoma and per...Objective: To study the diagnostic method, surgical management and complications of the tracheal malignant tumor, as well as the characteristics of plasmocytoma. Methods: One patient with tracheal plasmocytoma and pertinent literature were analyzed retrospectively. Results: Resection of the tracheal tumor and reconstruction of the trachea were performed successfully in this case, and the pathological diagnosis is plasmocytoma. Conclusion: The nature, location and extent of tracheal tumor are precisely determined from radiologic studies before resection, as well as tracheal intubation and tracheal anastomosis without tension in operative procedures, are very important for triumphal operation. Even extramedullary plasmocytoma may occur in a lot of organs, but the incidence of it is rare. Both surgery and radiotherapy are cardinal methods for extramedullary plasmocytoma.展开更多
Biological aerated filters have many advantages such as small volume and high treatment efficiency. This research focused on sewage treatment performance of integrated biological aerated filter (IBAF) under different ...Biological aerated filters have many advantages such as small volume and high treatment efficiency. This research focused on sewage treatment performance of integrated biological aerated filter (IBAF) under different conditions such as aeration, hydraulic retention time and the height of fillers layer, to identify the turn of marked affecting factor of removal performance through orthogonal experiments, optimize the function parameter of IBAF, reveal the regularity of sewage treatment of IBAF under different conditions, and adopt suitable measures to guarantee excess water quality of IBAF.展开更多
At a fully mechanized working face of a coal mine as prototype,we investigated,by simulation,the flow field and dust distribution during the process of its isolation by a curtain of air,using the CFD software, Fluent....At a fully mechanized working face of a coal mine as prototype,we investigated,by simulation,the flow field and dust distribution during the process of its isolation by a curtain of air,using the CFD software, Fluent.The results show that the air curtain installed on the shearer can effectively prevent the dust (especially the respirable dust)from diffusing into the work area of the operator,reducing the dust concentration on the side of the operator and greatly improving his working environment.The field application of the air curtain shows that the dust-isolation effect of an air curtain is quite noticeable.The isolation efficiency for respiratory dust is over 70%and,as well,it has good dust-isolation effect for nonrespiratory dust.The air curtain is a useful way to resolve the problem of dust-isolation at a fully mechanized working face.It has a practical background elsewhere with more extensive applications.展开更多
AIM: To investigate the pathophysiology of irritable bowel syndrome (IBS) by comparing the global mucosal metabolic profiles of IBS patients with those of healthy controls. METHODS: Fifteen IBS patients fulfilling...AIM: To investigate the pathophysiology of irritable bowel syndrome (IBS) by comparing the global mucosal metabolic profiles of IBS patients with those of healthy controls. METHODS: Fifteen IBS patients fulfilling the Rome II criteria, and nine healthy volunteers were included in the study. A combined lipidomics (UPLC/MS) and metabolomics (GC × GC-TOF) approach was used to achieve global metabolic profiles of mucosal biopsies from the ascending colon. RESULTS: Overall, lipid levels were elevated in patients with IBS. The most significant upregulation was seen for pro-inflammatory lysophosphatidylcholines. Other lipid groups that were significantly upregulated in IBS patients were lipotoxic ceramides, glycosphingolipids, and di-and triacylglycerols. Among the meo tabolites, the cyclic ester 2(3H)-furanone was almost 14-fold upregulated in IBS patients compared to healthy subjects (P = 0.03). CONCLUSION: IBS mucosa is characterised by a distinct pro-inflammatory and lipotoxic metabolic profile. Especially, there was an increase in several lipid species such as lysophospholipids and ceramides.展开更多
Data fusion, a new research domain, is the integration and extension of modem information techniques and many other subjects. The data fusion concept is introduced and the Dempster-Shafer evidence deduction is describ...Data fusion, a new research domain, is the integration and extension of modem information techniques and many other subjects. The data fusion concept is introduced and the Dempster-Shafer evidence deduction is described and applied to oil and gas detection. An example of the method is shown using numerical simulation data. The processing result indicates that the data fusion method can be widely used in hydrocarbon detection.展开更多
Qinghai Province is an important component of the Qinghai-Tibet Plateau in China. Scientific evaluation of the suitability of Qinghai's climate for tourism can contribute to overcoming obstacles posed by climate o...Qinghai Province is an important component of the Qinghai-Tibet Plateau in China. Scientific evaluation of the suitability of Qinghai's climate for tourism can contribute to overcoming obstacles posed by climate on sustainable tourism development in Qinghai Province, including disparities between the low and high seasons, high altitude health concerns, and weather events. A tourism climate suitability evaluation model of the Qinghai-Tibet Plateau is constructed (Tourism Climate Suitability Index, or TCSI), and tourism climate suitability is comprehensively evaluated for Qinghai Province from climate data from 1960 to 2009. Results show that: (I) There is clear distributional characteristics of spatial-temporal variability of TCSI values in Qinghai Province. (II) Tourism climate suitability in Qinghai Province has significant seasonal and regional differences. The year is divided into a very suitable period (July and August), suitable tourism periods (from April and October), less suitable periods (From Nov to Mar). June to August is the most suitable tourism period in Qinghai. Qinghai Province is divided into five levels of tourism climate suitability: most suitable regions, very suitable regions, suitable regions, less suitable regions, and unsuitable region. (III) The key factor which influences regional differences in tourism climatic suitability is atmospheric oxygen. And the key factors which chiefly influence seasonal differences of tourism climate suitability are temperature and humidity, the wind chill factor, and barrier weather.展开更多
The air quality directive (2008/50/EC (of the European Parliament and of the Council of 21 May 2008)) requires European Member States to design appropriate AQPs (air quality plans) for zones and agglomerations w...The air quality directive (2008/50/EC (of the European Parliament and of the Council of 21 May 2008)) requires European Member States to design appropriate AQPs (air quality plans) for zones and agglomerations where the air quality does not comply with the limit values and to assess possible emission reduction measures to decrease concentration levels. The Portuguese agglomeration of Porto Litoral is one of the several European Union urban areas that had to develop and implement AQPs to reduce particulate matter (PM10). The AQPs were initially designed based on a scenario approach and using an air quality model, which was applied over the study region for the reference situation with the current PM10 emissions, and for a reduction scenario with PM10 emissions re-estimated considering the implementation of abatement measures. Aiming to cost-efficiently optimize Porto Litoral PM10 abatement measures, the assessment procedure was repeated using an optimization approach based on the RIAT + (regional integrated assessment tool +). Porto Litoral urban area's technical and non-technical measures were characterized (including associated costs) and, through the application of the air quality model to 20 emissions abatement scenarios, S-R (source-receptor) relationships were created. This paper comparatively describes the air quality plans designed to improve PM10 levels in the Porto Litoral agglomeration based on both the scenario analysis and the optimization approach.展开更多
Existed evidences show that airborne transmission of human respiratory droplets may be related with the spread of some infectious disease, such as severe acute respiratory syndrome (SARS) and H1N1 pandemic. Non-phar...Existed evidences show that airborne transmission of human respiratory droplets may be related with the spread of some infectious disease, such as severe acute respiratory syndrome (SARS) and H1N1 pandemic. Non-pharmaceutical approaches, including ventilation system and personal protection, are believed to have certain positive effects on the reduction of co-occupant's inhalation. This work then aims to numerically study the performances of mouth covering on co-occupant's exposure under mixing ventilation (MV), under-floor air distribution (UFAD) and displacement ventilation (DV) system, using drift-flux model. Desk partition, as one generally employed arrangement in plan office, is also investigated under MV. The dispersion of 1, 5 and 10 grn droplet residuals are numerically calculated and CO2 is used to represent tracer gas. The results show that using mouth covering by the infected person can reduce the co-occupant's inhalation greatly by interrupting direct spread of the expelled droplets, and best performance can be achieved under DV since the coughed air is mainly confined in the microenvironment of the infected person. The researches under MV show that the two interventions, mouth covering and desk partition, achieve almost the sarae inhalation for fine droplets while the inhalation of the co-occupant is lower when using mouth covering for large droplets.展开更多
Environmental temperature is a major factor affecting animal performance in South China. With global warming, heat stress will become more and more serious. This paper reviewed the effects of heat stress on metabolism...Environmental temperature is a major factor affecting animal performance in South China. With global warming, heat stress will become more and more serious. This paper reviewed the effects of heat stress on metabolism of proteins, glucose, fat and energy in skeletal muscle and related mechanisms so as to provide theoretical guidance for alleviating heat stress and improving production performance of animal suffering from heat stress.展开更多
Proteus syndrome is an extremely rare congenital disorder that produces multifocal overgrowth of tissue. This report presents a surgical case of a large lipoma in the abdominal wall of a patient with Proteus syndrome....Proteus syndrome is an extremely rare congenital disorder that produces multifocal overgrowth of tissue. This report presents a surgical case of a large lipoma in the abdominal wall of a patient with Proteus syndrome. She was diagnosed with Proteus syndrome based on certain diagnostic criteria. The neoplasm increased in size gradually, producing hemihypertrophy of her left lower extremity and trunk, and spread to her retroperitoneum and her left abdominal wall. She experienced gradually progressive constipation, nausea, vomiting, and abdominal pain. Computed tomography (CT) of the abdomen demonstrated a large mass in the subcutaneous adipose tissue of the left lower abdominal wall which measured 12 cm×8 cm×6 cm in diameter and encased the left colon. This mass in the abdominal wall was excised. The weight of the excised mass was 1550 g. The histopathological diagnosis of this mass was lipoma. After surgery, the encasement of the left colon was improved, and the patient was able to move her bowels twice per day. The excision of the large lipoma in the abdominal wall contributed to the improved bowel passage in this patient with Proteus syndrome.展开更多
Business Directory defines economic power as "conditions of having sufficient productive resources at command that give the capacity to make and enforce economic decisions, such as allocation of resources and apporti...Business Directory defines economic power as "conditions of having sufficient productive resources at command that give the capacity to make and enforce economic decisions, such as allocation of resources and apportioning of goods and services". This qualitative definition may be sufficient for general discussions, but it does not offer any quantitative measurements for management and control. Is there a way to measure economic power for analysis and synthesis of economic systems in this 21st century? This paper answers this question by introducing a set of quantitative terms from the field of electrical engineering, used in power measurement and control of electrical systems. Circuit theory concepts are introduced to show how the relationship between cash and cash flow in finance is analogous to that of electric charge and electric current and how education level, as economic potential, is analogous to electrical potential that causes current to flow in a circuit. An individual is identified as the basic cash flow source in the economy. Circuit models for an individual as well as a typical production facility are developed and demonstrated with an example. Equations for the measurement of economic power, losses, efficiency, and power factor are presented. It is shown that the individuals are the basic cash flow sources and producers of economic power.展开更多
A combined method of numerical simulation and field testing was adopted in this study in the interest of solving the problem of hard to control high concentrate dusts on a fully mechanized mining face. In addi- tion, ...A combined method of numerical simulation and field testing was adopted in this study in the interest of solving the problem of hard to control high concentrate dusts on a fully mechanized mining face. In addi- tion, the dust suppression effect of a multi-direction whirling air curtain was studied in this paper. Under the influence of the wall attachment effect, the compressed air which blows out from the two-phase or three-phase radial outlets on the generator of the air curtain can form a multi-direction whirling air curtain, which can cover the whole roadway section of a fully mechanized mining face. The traditional method of controlling dust is a forcing system with exhaust overlap which has the major disadvantage of lacking a jet effect and consequently results in poor dust control. It is difficult to form the air flow field within the range of Lp ≤ 5√S. However, due to the effect of this novel system, the radial airflow can be turned into axial airflow allowing fresh air to flow through the length of the heading. The air flow field which is good at controlling dust diffusion can be formed 12.8 m from the heading face. Furthermore, the field measurement results show that before the application of a multi-direction whirling air curtain, the dust concentration is 348.6 mg/m^3 and 271.4 mg/m^3 respectively at the roadway cross-section measurement points which are 5 m and 10 m from the heading face. However, after the application of the multi-direction whirling air curtain, the dust concentration is only 61.2 mg/m3 and 14.8 mg/m^3, respectively. Therefore, the dust control effect of a multi-direction whirling air curtain is obvious.展开更多
In order to improve efficiency of coal seam gas drainage, many fracturing techniques, such as waterjet fracturing, hydraulic fracturing and explosive fracturing, etc, have been developed and widely used in China coal ...In order to improve efficiency of coal seam gas drainage, many fracturing techniques, such as waterjet fracturing, hydraulic fracturing and explosive fracturing, etc, have been developed and widely used in China coal mining industry. How- ever, during the engineering applications, it is observed that the efficiency of gas drainage initially improves, but reduces there- after. Thus, it is speculated that the contrasts in coalbed methane drainage efficiency may reflect variation of the closure be- havior of the artificial fracture created. Based on comprehensive gas drainage monitoring data in underground coal mines, the work presented herein uses numerical simulation to show the behavior of the time-dependent closure of coal seam fractures as- sociated with various levels of waterjet fracturing parameters and geomechanical conditions.展开更多
The origins and main control methods of gas in coal seams were introduced cursorily, and the processes that need to be done in controlling gas, which includes prediction of gas emissions, drainage systems, the means o...The origins and main control methods of gas in coal seams were introduced cursorily, and the processes that need to be done in controlling gas, which includes prediction of gas emissions, drainage systems, the means of prevention of gas outbursts, and some suggestions were put forward. The characteristic of different gas emissions and the corresponding counter measures were presented, and & case study of simultaneous extraction of coal and gas in Xieyi Coal Mine was carried out by coal mining and gas extraction without coal-pillar. The field application shows that gas drainage ratio in panel 5121(0) averages about 90% and reaches as high as 95~/0, which will give beneficial references to gas control in coal mines.展开更多
To compare effect of high-frequency oscillation ventilation (HFOV) and conventional mandatory ventilation (CMV) on lung injury development in rabbit with acute respiratory distress syndrome ( ARDS). Methods Anim...To compare effect of high-frequency oscillation ventilation (HFOV) and conventional mandatory ventilation (CMV) on lung injury development in rabbit with acute respiratory distress syndrome ( ARDS). Methods Animals that underwent saline lung lavage to produce lung injury were randomized to one of the two treatment groups ( HFOV or CMV, n =6). PaCO2 was maintained between 35 -45mmHg and arterial oxygen saturation ( SaO2 ) was maintain 〉 88% by adjusting corresponding ventilator parameters. Ventilation period was 6h. Lung fluids were aspirated before and at the end of ventilation for cell analysis. Then the animals were euthanized, lung tissue was removed for wet/dry weight measurement, light and electron microscopic examination. Besults The difference of artery blood gas analyses(pH, PaO2, PaCO2 ) between HFOV and CMV was insignificant. The difference between HFOV and CMV in cytological examination of lung fluids, wet/dry weight measurement was also insignificant. But compared with CMV, HFOV not only reduced the area of lung injury, but also reduced lung injury score in light and electron microscopic examination. Conclusion When same artery blood gas analysis was obtained, HFOV significantly reduced lung injury development in ARDS animal than CMV. As a lung protection strategy, HFOV can be used in the treatment of ARDS.展开更多
Petrochemicals play a vital role in the economy of any nation. The products of the industry are the building blocks in many industries as they deepen the forward and backward linkages of the petroleum sector with the ...Petrochemicals play a vital role in the economy of any nation. The products of the industry are the building blocks in many industries as they deepen the forward and backward linkages of the petroleum sector with the rest of the economy. The industry uses a variety of hydrocarbon feedstock such as different cuts of naphtha from refinery and natural gas. One of the problems facing the industry is lack of reliable feedstock supplies. Nigeria has the potential to be a major petrochemicals producer. With proven gas reserves currently estimated at 187 tcf, not much has been accomplished with respect to the effective exploitation and utilization of this resource as most of the nation's natural gas production has been flared, liquefied for export or re-injected to enhance greater crude oil recovery. It has become imperative to further find ways to exploit and utilize the nation's natural gas reserves and translate it to the improvement of the nation's economy. Steam reforming of natural gas is one of the avenues for conversion of natural gas to petrochemicals. This paper, however, reviews various ways of utilizing natural gas, examines the process details of steam reforming of natural gas as a route to optimized natural gas utilization and industrialization in Nigeria. Syngas (synthesis gas) is a versatile feedstock for most petrochemicals and chemical intermediates. Thus utilizing natural gas in this way would strengthen the petrochemical industry making it possible for the country to change from raw materials to value-added products supplier, boost the economy and solve the "hydra-headed" problem of unemployment in Nigeria with its multiplier employment effect.展开更多
文摘Objective: To observe the risk factors of thrombosis in patients with obstructive sleep apnea hypopnea syndrome (OSAHS).Methods: From February 2001 to April 2003, 24 patients with moderate and severe OSAHS (OSAHS group) and 19 healthy adults (control group) were recruited. Their blood samples were drawn at 6∶00 and 16∶00 respectively for testing hemocrit, platelet aggregation (PAG), whole blood viscosity (WBV), prothrombin time (PT), activated partial thromboplastin time (APTT), plasma fibrinogen (Fng) and endothelin (ET).Results: There was a significantly higher hemocrit, WBV, Fng and ET as well as a significant shortening of PT and APTT at 6∶00 than that at 16∶00 in OSAHS group. However, there was no significant difference in all testing items between 6∶00 and 16∶00 in control group. The hemocrit, WBV, PAG, plasma Fng and ET were significantly higher, and PT and APTT were obviously shorter at 6∶00 in OSAHS group than those at 6∶00 in control group. A higher hemocrit, PAG, plasma Fng and ET, a longer PT and APTT were observed at 16∶00 in OSAHS group, compared with those at 16∶00 in control group.Conclusion: In OSAHS patients there were striking risk factors of thrombosis, which is more remarkable in the early morning than in the afternoon.
文摘Objective This study aimed to assess the protective value of adiponectin(APN)in pancreatic islet injury induced by chronic intermittent hypoxia(CIH).Methods Sixty rats were randomly divided into three groups:normal control(NC)group,CIH group,and CIH with APN supplement(CIH+APN)group.After 5 weeks of CIH exposure,we conducted oral glucose tolerance tests(OGTT)and insulin released test(IRT),examined and compared the adenosine triphosphate(ATP)levels,mitochondrial membrane potential(MMP)levels,reactive oxygen species(ROS)levels,enzymes gene expression levels of Ant1,Cs,Hmox1,and Cox4 i1 which represented mitochondrial tricarboxylic acid cycle function,the protein and gene expression levels of DRP1,FIS1,MFN1,and OPA1 which represented mitochondrial fusion and division,and the protein expression levels of BAX,BCL-2,cleaved Caspase-3,and cleaved PARP which represented mitochondrial associated apoptosis pathway of pancreatic islet.Results OGTT and IRT showed blood glucose and insulin levels had no differences among the NC,CIH and CIH+APN groups(both P>0.05)at 0 min,20 min,30 min,60 min,120 min.However,we found that compared to NC group,CIH increased the ROS level,reduced ATP level and MMP level.The islets of CIH exposed rats showed reduced gene expression levels of Ant1,Cs,Hmox1,and Cox4 i1,decreased protein and gene expression levels of MFN1 and OPA1,increased protein and gene expression levels of DRP1 and FIS1,increased protein expression levels of cleaved Caspase-3 and cleaved PARP,with lower ratio of BCL-2/BAX at protein expression level.All the differences among three groups were statistically significant.APN treated CIH rats showed mitigated changes in the above measurements associated with islet injuries.Conclusion APN may ameliorate the pancreatic islet injury induced by CIH via inhibiting the imbalance in mitochondrial fusion and division.
文摘Objective: To study the diagnostic method, surgical management and complications of the tracheal malignant tumor, as well as the characteristics of plasmocytoma. Methods: One patient with tracheal plasmocytoma and pertinent literature were analyzed retrospectively. Results: Resection of the tracheal tumor and reconstruction of the trachea were performed successfully in this case, and the pathological diagnosis is plasmocytoma. Conclusion: The nature, location and extent of tracheal tumor are precisely determined from radiologic studies before resection, as well as tracheal intubation and tracheal anastomosis without tension in operative procedures, are very important for triumphal operation. Even extramedullary plasmocytoma may occur in a lot of organs, but the incidence of it is rare. Both surgery and radiotherapy are cardinal methods for extramedullary plasmocytoma.
文摘Biological aerated filters have many advantages such as small volume and high treatment efficiency. This research focused on sewage treatment performance of integrated biological aerated filter (IBAF) under different conditions such as aeration, hydraulic retention time and the height of fillers layer, to identify the turn of marked affecting factor of removal performance through orthogonal experiments, optimize the function parameter of IBAF, reveal the regularity of sewage treatment of IBAF under different conditions, and adopt suitable measures to guarantee excess water quality of IBAF.
基金Financial support for this work,provided by the National Natural Science Foundation of China(No.50974060)the State Safety Production Science and Technology Development Plan (No.06-396)
文摘At a fully mechanized working face of a coal mine as prototype,we investigated,by simulation,the flow field and dust distribution during the process of its isolation by a curtain of air,using the CFD software, Fluent.The results show that the air curtain installed on the shearer can effectively prevent the dust (especially the respirable dust)from diffusing into the work area of the operator,reducing the dust concentration on the side of the operator and greatly improving his working environment.The field application of the air curtain shows that the dust-isolation effect of an air curtain is quite noticeable.The isolation efficiency for respiratory dust is over 70%and,as well,it has good dust-isolation effect for nonrespiratory dust.The air curtain is a useful way to resolve the problem of dust-isolation at a fully mechanized working face.It has a practical background elsewhere with more extensive applications.
基金Supported by Valio Ltd and the Finnish Funding Agency for Technology and Innovation(TEKES)the preparation of this manuscript was funded in part by the Academy of Finland
文摘AIM: To investigate the pathophysiology of irritable bowel syndrome (IBS) by comparing the global mucosal metabolic profiles of IBS patients with those of healthy controls. METHODS: Fifteen IBS patients fulfilling the Rome II criteria, and nine healthy volunteers were included in the study. A combined lipidomics (UPLC/MS) and metabolomics (GC × GC-TOF) approach was used to achieve global metabolic profiles of mucosal biopsies from the ascending colon. RESULTS: Overall, lipid levels were elevated in patients with IBS. The most significant upregulation was seen for pro-inflammatory lysophosphatidylcholines. Other lipid groups that were significantly upregulated in IBS patients were lipotoxic ceramides, glycosphingolipids, and di-and triacylglycerols. Among the meo tabolites, the cyclic ester 2(3H)-furanone was almost 14-fold upregulated in IBS patients compared to healthy subjects (P = 0.03). CONCLUSION: IBS mucosa is characterised by a distinct pro-inflammatory and lipotoxic metabolic profile. Especially, there was an increase in several lipid species such as lysophospholipids and ceramides.
文摘Data fusion, a new research domain, is the integration and extension of modem information techniques and many other subjects. The data fusion concept is introduced and the Dempster-Shafer evidence deduction is described and applied to oil and gas detection. An example of the method is shown using numerical simulation data. The processing result indicates that the data fusion method can be widely used in hydrocarbon detection.
基金funded by National Science and Technology Support Plan of China (No. 2009BAH50B01-03)National Natural Science Foundation of China (No.41171435)the Major Projects of the National Social Science Foundation of China (No.10zd&051) and Research on Ecotourism Development Planning of Three Rivers Sources Region in Qinghai Province
文摘Qinghai Province is an important component of the Qinghai-Tibet Plateau in China. Scientific evaluation of the suitability of Qinghai's climate for tourism can contribute to overcoming obstacles posed by climate on sustainable tourism development in Qinghai Province, including disparities between the low and high seasons, high altitude health concerns, and weather events. A tourism climate suitability evaluation model of the Qinghai-Tibet Plateau is constructed (Tourism Climate Suitability Index, or TCSI), and tourism climate suitability is comprehensively evaluated for Qinghai Province from climate data from 1960 to 2009. Results show that: (I) There is clear distributional characteristics of spatial-temporal variability of TCSI values in Qinghai Province. (II) Tourism climate suitability in Qinghai Province has significant seasonal and regional differences. The year is divided into a very suitable period (July and August), suitable tourism periods (from April and October), less suitable periods (From Nov to Mar). June to August is the most suitable tourism period in Qinghai. Qinghai Province is divided into five levels of tourism climate suitability: most suitable regions, very suitable regions, suitable regions, less suitable regions, and unsuitable region. (III) The key factor which influences regional differences in tourism climatic suitability is atmospheric oxygen. And the key factors which chiefly influence seasonal differences of tourism climate suitability are temperature and humidity, the wind chill factor, and barrier weather.
文摘The air quality directive (2008/50/EC (of the European Parliament and of the Council of 21 May 2008)) requires European Member States to design appropriate AQPs (air quality plans) for zones and agglomerations where the air quality does not comply with the limit values and to assess possible emission reduction measures to decrease concentration levels. The Portuguese agglomeration of Porto Litoral is one of the several European Union urban areas that had to develop and implement AQPs to reduce particulate matter (PM10). The AQPs were initially designed based on a scenario approach and using an air quality model, which was applied over the study region for the reference situation with the current PM10 emissions, and for a reduction scenario with PM10 emissions re-estimated considering the implementation of abatement measures. Aiming to cost-efficiently optimize Porto Litoral PM10 abatement measures, the assessment procedure was repeated using an optimization approach based on the RIAT + (regional integrated assessment tool +). Porto Litoral urban area's technical and non-technical measures were characterized (including associated costs) and, through the application of the air quality model to 20 emissions abatement scenarios, S-R (source-receptor) relationships were created. This paper comparatively describes the air quality plans designed to improve PM10 levels in the Porto Litoral agglomeration based on both the scenario analysis and the optimization approach.
基金funded by Research Grant Committee of the Hong Kong SAR government (RGC No. PolyU5265/08E)
文摘Existed evidences show that airborne transmission of human respiratory droplets may be related with the spread of some infectious disease, such as severe acute respiratory syndrome (SARS) and H1N1 pandemic. Non-pharmaceutical approaches, including ventilation system and personal protection, are believed to have certain positive effects on the reduction of co-occupant's inhalation. This work then aims to numerically study the performances of mouth covering on co-occupant's exposure under mixing ventilation (MV), under-floor air distribution (UFAD) and displacement ventilation (DV) system, using drift-flux model. Desk partition, as one generally employed arrangement in plan office, is also investigated under MV. The dispersion of 1, 5 and 10 grn droplet residuals are numerically calculated and CO2 is used to represent tracer gas. The results show that using mouth covering by the infected person can reduce the co-occupant's inhalation greatly by interrupting direct spread of the expelled droplets, and best performance can be achieved under DV since the coughed air is mainly confined in the microenvironment of the infected person. The researches under MV show that the two interventions, mouth covering and desk partition, achieve almost the sarae inhalation for fine droplets while the inhalation of the co-occupant is lower when using mouth covering for large droplets.
基金Supported by Key Project of Natural Science Foundation of Hubei Province(2013CFA100)National Natural Science Foundation of China(31472117)
文摘Environmental temperature is a major factor affecting animal performance in South China. With global warming, heat stress will become more and more serious. This paper reviewed the effects of heat stress on metabolism of proteins, glucose, fat and energy in skeletal muscle and related mechanisms so as to provide theoretical guidance for alleviating heat stress and improving production performance of animal suffering from heat stress.
文摘Proteus syndrome is an extremely rare congenital disorder that produces multifocal overgrowth of tissue. This report presents a surgical case of a large lipoma in the abdominal wall of a patient with Proteus syndrome. She was diagnosed with Proteus syndrome based on certain diagnostic criteria. The neoplasm increased in size gradually, producing hemihypertrophy of her left lower extremity and trunk, and spread to her retroperitoneum and her left abdominal wall. She experienced gradually progressive constipation, nausea, vomiting, and abdominal pain. Computed tomography (CT) of the abdomen demonstrated a large mass in the subcutaneous adipose tissue of the left lower abdominal wall which measured 12 cm×8 cm×6 cm in diameter and encased the left colon. This mass in the abdominal wall was excised. The weight of the excised mass was 1550 g. The histopathological diagnosis of this mass was lipoma. After surgery, the encasement of the left colon was improved, and the patient was able to move her bowels twice per day. The excision of the large lipoma in the abdominal wall contributed to the improved bowel passage in this patient with Proteus syndrome.
文摘Business Directory defines economic power as "conditions of having sufficient productive resources at command that give the capacity to make and enforce economic decisions, such as allocation of resources and apportioning of goods and services". This qualitative definition may be sufficient for general discussions, but it does not offer any quantitative measurements for management and control. Is there a way to measure economic power for analysis and synthesis of economic systems in this 21st century? This paper answers this question by introducing a set of quantitative terms from the field of electrical engineering, used in power measurement and control of electrical systems. Circuit theory concepts are introduced to show how the relationship between cash and cash flow in finance is analogous to that of electric charge and electric current and how education level, as economic potential, is analogous to electrical potential that causes current to flow in a circuit. An individual is identified as the basic cash flow source in the economy. Circuit models for an individual as well as a typical production facility are developed and demonstrated with an example. Equations for the measurement of economic power, losses, efficiency, and power factor are presented. It is shown that the individuals are the basic cash flow sources and producers of economic power.
基金supported by the Key Program of the Coal Joint Funds of the National Natural Science Foundation of China (No.U1261205)the Youth Program of National Natural Science Foundation of China (No.51404147)+2 种基金the Class General Financial Grant from the China Postdoctoral Science Foundation (No.2015M570601)the Scientific Research Foundation of Shandong University of Science and Technology for Recruited Talents (No.2014RCJJ029)the State Key Laboratory of Mining Disaster Prevention and Control Co-founded by Shandong Province and the Ministry of Science and Technology,Shandong University of Science and Technology (No.MDPC2013ZR02)
文摘A combined method of numerical simulation and field testing was adopted in this study in the interest of solving the problem of hard to control high concentrate dusts on a fully mechanized mining face. In addi- tion, the dust suppression effect of a multi-direction whirling air curtain was studied in this paper. Under the influence of the wall attachment effect, the compressed air which blows out from the two-phase or three-phase radial outlets on the generator of the air curtain can form a multi-direction whirling air curtain, which can cover the whole roadway section of a fully mechanized mining face. The traditional method of controlling dust is a forcing system with exhaust overlap which has the major disadvantage of lacking a jet effect and consequently results in poor dust control. It is difficult to form the air flow field within the range of Lp ≤ 5√S. However, due to the effect of this novel system, the radial airflow can be turned into axial airflow allowing fresh air to flow through the length of the heading. The air flow field which is good at controlling dust diffusion can be formed 12.8 m from the heading face. Furthermore, the field measurement results show that before the application of a multi-direction whirling air curtain, the dust concentration is 348.6 mg/m^3 and 271.4 mg/m^3 respectively at the roadway cross-section measurement points which are 5 m and 10 m from the heading face. However, after the application of the multi-direction whirling air curtain, the dust concentration is only 61.2 mg/m3 and 14.8 mg/m^3, respectively. Therefore, the dust control effect of a multi-direction whirling air curtain is obvious.
文摘In order to improve efficiency of coal seam gas drainage, many fracturing techniques, such as waterjet fracturing, hydraulic fracturing and explosive fracturing, etc, have been developed and widely used in China coal mining industry. How- ever, during the engineering applications, it is observed that the efficiency of gas drainage initially improves, but reduces there- after. Thus, it is speculated that the contrasts in coalbed methane drainage efficiency may reflect variation of the closure be- havior of the artificial fracture created. Based on comprehensive gas drainage monitoring data in underground coal mines, the work presented herein uses numerical simulation to show the behavior of the time-dependent closure of coal seam fractures as- sociated with various levels of waterjet fracturing parameters and geomechanical conditions.
文摘The origins and main control methods of gas in coal seams were introduced cursorily, and the processes that need to be done in controlling gas, which includes prediction of gas emissions, drainage systems, the means of prevention of gas outbursts, and some suggestions were put forward. The characteristic of different gas emissions and the corresponding counter measures were presented, and & case study of simultaneous extraction of coal and gas in Xieyi Coal Mine was carried out by coal mining and gas extraction without coal-pillar. The field application shows that gas drainage ratio in panel 5121(0) averages about 90% and reaches as high as 95~/0, which will give beneficial references to gas control in coal mines.
文摘To compare effect of high-frequency oscillation ventilation (HFOV) and conventional mandatory ventilation (CMV) on lung injury development in rabbit with acute respiratory distress syndrome ( ARDS). Methods Animals that underwent saline lung lavage to produce lung injury were randomized to one of the two treatment groups ( HFOV or CMV, n =6). PaCO2 was maintained between 35 -45mmHg and arterial oxygen saturation ( SaO2 ) was maintain 〉 88% by adjusting corresponding ventilator parameters. Ventilation period was 6h. Lung fluids were aspirated before and at the end of ventilation for cell analysis. Then the animals were euthanized, lung tissue was removed for wet/dry weight measurement, light and electron microscopic examination. Besults The difference of artery blood gas analyses(pH, PaO2, PaCO2 ) between HFOV and CMV was insignificant. The difference between HFOV and CMV in cytological examination of lung fluids, wet/dry weight measurement was also insignificant. But compared with CMV, HFOV not only reduced the area of lung injury, but also reduced lung injury score in light and electron microscopic examination. Conclusion When same artery blood gas analysis was obtained, HFOV significantly reduced lung injury development in ARDS animal than CMV. As a lung protection strategy, HFOV can be used in the treatment of ARDS.
文摘Petrochemicals play a vital role in the economy of any nation. The products of the industry are the building blocks in many industries as they deepen the forward and backward linkages of the petroleum sector with the rest of the economy. The industry uses a variety of hydrocarbon feedstock such as different cuts of naphtha from refinery and natural gas. One of the problems facing the industry is lack of reliable feedstock supplies. Nigeria has the potential to be a major petrochemicals producer. With proven gas reserves currently estimated at 187 tcf, not much has been accomplished with respect to the effective exploitation and utilization of this resource as most of the nation's natural gas production has been flared, liquefied for export or re-injected to enhance greater crude oil recovery. It has become imperative to further find ways to exploit and utilize the nation's natural gas reserves and translate it to the improvement of the nation's economy. Steam reforming of natural gas is one of the avenues for conversion of natural gas to petrochemicals. This paper, however, reviews various ways of utilizing natural gas, examines the process details of steam reforming of natural gas as a route to optimized natural gas utilization and industrialization in Nigeria. Syngas (synthesis gas) is a versatile feedstock for most petrochemicals and chemical intermediates. Thus utilizing natural gas in this way would strengthen the petrochemical industry making it possible for the country to change from raw materials to value-added products supplier, boost the economy and solve the "hydra-headed" problem of unemployment in Nigeria with its multiplier employment effect.