药品安全关系到公众身体健康和生命安全,已成为全球关注的社会问题。目前,针对药品安全领域的研究已越来越深入,注重药品风险管理的理念扩展到药品的整个产品生命周期。本文将重点关注上市后药品安全,对美国药品风险管理政策开展研...药品安全关系到公众身体健康和生命安全,已成为全球关注的社会问题。目前,针对药品安全领域的研究已越来越深入,注重药品风险管理的理念扩展到药品的整个产品生命周期。本文将重点关注上市后药品安全,对美国药品风险管理政策开展研究,阐述美国药品风险管理的历史进程,特别是重点阐述和分析2007年美国食品药品管理修正案(Foodand Drug Administration AmendmentAct,以下简称FDAAA)所推出的“风险评估和缓减策略”(Risk Evaluation and MitigationStrategies,以下简称REMS)的主要内容和实施情况。对我国目前正在开展的药物警戒工作作简要回顾与分析,引入药品风险管理的先进经验与做法,以期对我国正在开展的药物警戒给予一定借鉴,并对我国药品风险管理予以近景展望。展开更多
Seagrass is not only known for its ecological role,but also for its high capacity on the carbon sequestration.Although the area of seagrass meadows was less than 0.2%of the world’s oceans,the yearly organic carbon bu...Seagrass is not only known for its ecological role,but also for its high capacity on the carbon sequestration.Although the area of seagrass meadows was less than 0.2%of the world’s oceans,the yearly organic carbon burial of seagrass reached 10%of that in the ocean.Anthropogenic activities in the past two decades and the climate change have led to a significant decrease of seagrass meadow.Since seagrass is widely distributed along the coastline of China,it is necessary to put more efforts on the seagrass conservation and restoration,which will consequently be a suitable nature based solution for mitigating the climate change.This paper provides a comprehensive review on the following five aspects:1)the seagrass distribution in China;2)the role that seagrass plays in the climate mitigation;3)carbon sequestration of seagrass in China;4)loss of seagrass habitats and 5)the restoration of seagrass habitat in China since 2013.Current research gap and prospective research direction were also pointed out in this study.展开更多
Electrorheologica (ER) technique is a developing technology. In a wide range of engineering applications of ER fluid, shock absorbers employing ER fluids, whose damping force can be controlled continuously and promptl...Electrorheologica (ER) technique is a developing technology. In a wide range of engineering applications of ER fluid, shock absorbers employing ER fluids, whose damping force can be controlled continuously and promptly through electric signals, is one of the most prospective applications of ER fluid. In this paper, the theoretical midel and method to predict the damping force of ERF shock absorbers are established.展开更多
文摘药品安全关系到公众身体健康和生命安全,已成为全球关注的社会问题。目前,针对药品安全领域的研究已越来越深入,注重药品风险管理的理念扩展到药品的整个产品生命周期。本文将重点关注上市后药品安全,对美国药品风险管理政策开展研究,阐述美国药品风险管理的历史进程,特别是重点阐述和分析2007年美国食品药品管理修正案(Foodand Drug Administration AmendmentAct,以下简称FDAAA)所推出的“风险评估和缓减策略”(Risk Evaluation and MitigationStrategies,以下简称REMS)的主要内容和实施情况。对我国目前正在开展的药物警戒工作作简要回顾与分析,引入药品风险管理的先进经验与做法,以期对我国正在开展的药物警戒给予一定借鉴,并对我国药品风险管理予以近景展望。
基金supported by 2021 China Postdoctoral International Exchange Program Introduced Project Tianjin Jointly Funded Pilot Project,and the science and technology project of CNOOC EnerTech-Safety and Environmental Protection Company(HFKJ-STS2022-02).
文摘Seagrass is not only known for its ecological role,but also for its high capacity on the carbon sequestration.Although the area of seagrass meadows was less than 0.2%of the world’s oceans,the yearly organic carbon burial of seagrass reached 10%of that in the ocean.Anthropogenic activities in the past two decades and the climate change have led to a significant decrease of seagrass meadow.Since seagrass is widely distributed along the coastline of China,it is necessary to put more efforts on the seagrass conservation and restoration,which will consequently be a suitable nature based solution for mitigating the climate change.This paper provides a comprehensive review on the following five aspects:1)the seagrass distribution in China;2)the role that seagrass plays in the climate mitigation;3)carbon sequestration of seagrass in China;4)loss of seagrass habitats and 5)the restoration of seagrass habitat in China since 2013.Current research gap and prospective research direction were also pointed out in this study.
文摘Electrorheologica (ER) technique is a developing technology. In a wide range of engineering applications of ER fluid, shock absorbers employing ER fluids, whose damping force can be controlled continuously and promptly through electric signals, is one of the most prospective applications of ER fluid. In this paper, the theoretical midel and method to predict the damping force of ERF shock absorbers are established.