一种基于多指标语言评价信息的聚类方法

针对一类特征指标值和指标权重均为语言评价信息的聚类问题,提出了一种新的聚类分析方法.首先对基于多指标语言评价信息的聚类问题进行了描述;然后依据传统的基于数值信息的编网模糊聚类分析方法的基本思路,在将语言短语转换成三角模糊数的基础上,给出了解决多指标语言评价信息聚类问题的计算步骤.最后,通过给出一个算例说明了所提出的聚类分析方法.该聚类方法拓宽了编网聚类分析方法在解决基于多指标语言评价信息聚类方面的应用.

一种基于群体语言相似矩阵的聚类方法

针对多个专家给出语言相似矩阵的聚类分析问题,提出一种新的编网聚类分析方法。首先描述具有群体语言相似矩阵的聚类问题并介绍近年来国际上最新发展的二元语义概念及其算子;其次,基于二元语义信息处理的方法,将每个专家给出的语言相似矩阵转化为二元语义形式,再采用二元语义集结算子进行群的集结;然后依据传统的编网聚类方法的基本思路,给出基于群体语言相似矩阵的聚类分析方法的计算步骤。最后通过一个算例说明了本文给出的方法。

单体、链节与高聚物

根据高中化学教材及高考考试要求,以实例从加聚反应和缩聚反应两大基本反应常见类型的特点进行分析,阐述了合成有机高分子化合物的形成原理,从而明确了如何确定高聚物的单体和链节的常用方法,较好的解决了高中有机化学中的一个难点。

Flax/Polylactic Acid(PLA)Core/Sheath Structural Composite Yarn Fabricated by Spindle Braiding Technique

The increasing demand for sustainable and environmentally friendly materials has driven research towards the development of green composites.In this work,the flax/polylactic acid(PLA)braided yarns were fabricated by braiding PLA filaments with 4 to 24 spindles on flax yarns.After curing at different temperatures(180℃and 190℃),the core/sheath structural flax/PLA composite yarns were manufactured.According to the results of the tensile test,the flax/PLA composite yarn with 4-spindle PLA yarns as a sheath layer and at a curing temperature of 180℃reached the maximum elastic modulus of about(5.79±0.65)GPa and the maximum tensile strength of about(162.17±18.18)MPa.This flax/PLA composite yarn with good mechanical properties would be suitable for green composites in the automobile manufacturing industry and building materials.

EFFECTIVE FEATURE ANALYSIS FOR COLOR IMAGE SEGMENTATION

An approach for color image segmentation is proposed based on the contributions of color features to segmentation rather than the choice of a particular color space. The determination of effective color features depends on the analysis of various color features from each tested color image via the designed feature encoding. It is different from the pervious methods where self organized feature map (SOFM) is used for constructing the feature encoding so that the feature encoding can self organize the effective features for different color images. Fuzzy clustering is applied for the final segmentation when the well suited color features and the initial parameter are available. The proposed method has been applied in segmenting different types of color images and the experimental results show that it outperforms the classical clustering method. The study shows that the feature encoding approach offers great promise in automating and optimizing the segmentation of color images.

Fabrication of a Knitted Biodegradable Stents for Tracheal Regeneration

Endoluminal stents for reinforcement and regeneration of human trachea have been developed by weft-knitting method on a small-diameter circular knitting machine. The constituent materials of the stent are Polyglactin, Polypropylene and Chitosan with Polyglactin and Polypropylene plate-stitched fabric acting as backbone while chitosan as matrix, respectively. The fabrication procedures including knitting and coating are described in this paper. Mechanical and animal tests have been carried out to evaluate the mechanical properties of the stents.

-449 C>G polymorphism of NFKB1 gene,coding nuclear factor-kappa-B,is associated with the susceptibility to ulcerative colitis

AIM:To clarify the association between a polymorphism-449 C>G(rs72696119) in 5'-UTR of NFKB1 with ulcerative colitis(UC).METHODS:The studied population comprised 639 subjects,including patients with UC(UC cases,n = 174) and subjects without UC(controls,n = 465).We employed polymerase chain reaction-single strand conformation polymorphism to detect the gene polymorphism.RESULTS:The rs72696119 G allele frequencies in controls and UC cases were 33.4% and 38.5%,respectively(P = 0.10).Genotype frequency of the GG homozygote in UC cases was significantly higher than that in controls(P = 0.017),and the GG homozygote was significantly associated with susceptibility to UC [odds ratio(OR),1.88;95%CI,1.13-3.14].In male subjects,the GG homozygote was associated with an increased risk for UC(OR,3.10;95%CI,1.47-6.54;P = 0.0053),whereas this association was not found in female subjects.In addition,the GG homozygote was significantly associated with the risk of non-continuous disease(OR,2.06;95%CI,1.12-3.79;P = 0.029),not having total colitis(OR,2.40;95%CI,1.09-3.80,P = 0.040),disease which developed before 20 years of age(OR,2.80;95%CI,1.07-7.32,P = 0.041),no hospitalization(OR,2.28;95%CI,1.29-4.05;P = 0.0090) and with a maximum of 8 or less on the UCDAI score(OR,2.45;95%CI,1.23-4.93;P = 0.022).CONCLUSION:Our results provide evidence that NFKB1 polymorphism rs72696119 was significantly associated with the development of UC.This polymorphism influences the susceptibility to and pathophysiological features of UC.

Creep Test of Polymer-matrix 3-D Braided Composites

The long-term creep behavior of polymer-matrix 3-D braided composites was studied by using the tensile creep test method, and the effect of braiding structure, braiding angle and fiber volume fraction were discussed. The creep curve appears as expected, and can be defined two phases, namely, the primary phase and the secondary phase. For each sample, strain increases with time rapidly, and then the strain rate decreases and appears to approach a constant rate of change (steady-state creep). The experiment results show that the creep resistant properties are improved while the braiding angle decreases or the fiber volume fraction increases, and that the five-directional braiding structure offers better creep resistant properties than the four-directional braiding structure.

Knockdown of long non-coding RNA LCPAT1 inhibits autophagy in lung cancer

Objective: Long non-coding RNAs(lnc RNAs) are involved in numerous biological processes in lung cancer cells. In our previous studies, we identified a lnc RNA, ENST00000439577, which is highly expressed in lung carcinomas, and termed it lung cancer progression-associated transcript 1(LCPAT1). To characterize the role of LCPAT1 in lung cancer, we conducted the current study.Methods: Expression of LCPAT1 and autophagy-associated markers in tumor tissues and lung cancer cell lines was determined by real-time quantitative polymerase chain reaction(q PCR). Hematoxylin and eosin(HE) staining, q PCR, Western blot, and immunohistochemistry were performed to evaluate xenografted tumor tissues. Autophagy induced by rapamycin was detected by Western blot and immunofluorescence in lung cancer cell lines.Results: Expression of LCPAT1 and microtubule-associated protein 1 light chain 3 beta(LC3B) was positively correlated in lung cancer. Knockdown of LCPAT1 inhibited tumor growth and suppressed cell autophagy in vivo. Moreover, LCPAT1 knockdown in lung cancer cell lines resulted in decreased autophagy-associated gene expression and alleviated the cell autophagy induced by rapamycin.Conclusions: We speculate that LCPAT1 plays a crucial role in regulating autophagy in lung cancer.

Physical Characteristics of Knitted Polyester Vascular Prostheses:Can the Wall Be Considered as a Scaffold for Tissue Regeneration?

Recent developments in endovascular surgery （EVAR） have opened new avenues to successfully treat aneurysms with percutaneous deployment of stent-grafts. Manufacturers have preferred to use woven fabrics or microporous tubes which are supported by metallic frames or stents. Woven fabrics are much thinner than knits and this permits the use of a smaller delivery catheter. However, since woven constructions are stiffer and have little porosity, the tissue ingrowth is poor or absent. On the other hand, knitted constructions can be considered as a scaffold for tissue ingrowth, and hence they represent an attractive alternative because of their open structure and better conformability in the case of balloon deployment. The present study was undertaken to analyze the properties of two knitted and crimped polyester arterial prototype prostheses, one with and the other without a gelatin coating as sealant. Two commercial controls were also included in the study, namely the uncoated knitted polyester vascular prosthesis VP1200K, and its sealed version, the gelatin coated polyester knitted Gelsoft device, manufactured by Vascutek Ltd., Scotland, UK. In vitro testing consisted of analyzing the and marphology of the yam and fabric structures, and measuring the physical and mechanical properties of the grafts, including the water prow.ability, the longitudinal and radial campliance, and the suture retention strength. In order to the different properties of the four samples, tests were performed on the gelatin coated of sealed devices before and after gelatin removal. The results provided a useful comparison between the prototypes and the commercial contorl devices. The latter used ten times the amount of gelatin which had been applied as a coating in order to achieve the same low level of impemeability to water. The different amounts of gelatin also explained the different mechanical performance, such as compliance, for these prototype and control prostheses.

Identifying Anomaly Aircraft Trajectories in Terminal Areas Based on Deep Autoencoder and Its Application in Trajectory Clustering

Anomalous trajectory detection and traffic flow classification for complicated airspace are of vital importance to safety and efficiency analysis.Some researchers employed density-based unsupervised machine learning method to exploit these trajectories related to air traffic control(ATC)actions.However,the quality of position data and the tiny density difference between traffic flows in the terminal area make it particularly challenging.To alleviate these two challenges,this paper proposes a novel framework which combines robust deep auto-encoder(RDAE)model and density peak(DP)clustering algorithm.Specifically,the RDAE model is utilized to reconstruct denoising trajectory and identify anomaly trajectories in the terminal area by two different regularizations.Then,the nonlinear components captured by the encoder of RDAE are input in the DP algorithm to classify the global traffic flows.An experiment on a terminal airspace at Guangzhou Baiyun Airport(ZGGG)with anomaly label shows that the proposed combination can automatically capture non-conventional spatiotemporal traffic patterns in the aircraft movement.The superiority of RDAE and combination are also demonstrated by visualizing and quantitatively evaluating the experimental results.

Shape memory behavior of SMPU knitted fabric

A preliminary investigation of shape memory (SM) effects of SMPU (shape memory polyurethane) knitting fabric is presented in this paper. Three SMPU knitted fabrics series with different content of SMPU fibers: 100% SMPU, 50% SMPU and 50% cotton, 16% SMPU and 84% cotton are designed and manufactured in our lab. Their shape memory behaviors at different temperatures are characterized in terms of bagging. Our experimental results showed that shape memory effect can be improved with increasing content of SMPU fibers. A comparison between Lycra and SMPU knitted fabrics was also made to validate the shape memory effects of SMPU knitted fabrics.

Human Cytomegalovirus UL138 Open Reading Frame Is Highly Conserved in Clinical Strains

Objective To investigate the variability of human cytomegalovirus （HCMV） UL138 open reading frame （ORF） in clinical strains. Methods HCMV UL138 ORF was amplified by polymerase chain reaction （PCR） and PCR amplification products were sequenced directly, and the data were analyzed in 19 clinical strains. Results LIL138 ORF in all 30 clinical strains was amplified successfully. Compared with that of Toledo strain, the nucleotide and amino acid sequence identifies of LIL138 ORF in all strains were 97.41% to 99.41% and 98.24% to 99.42%, respectively. All of the nucleofide mutations were substitutions. The spatial structure and post-translational modification sites of HL138 encoded proteins were conserved. The result of phylogenetic tree showed that HCMV HL138 sequence variations were not definitely related with different clinical symptoms. Conclusion HCMV UL138 ORF in clinical strains is high conservation, which might be helpful for UL138 encoded protein to play a role in latent infection of HCMV.

Research and Development of SWITRIM Code and Its Applications

The ftrst numerical simulation code package WITRIM has been developed to calculate the tritium inventory distribution and time-evolution in all sub-systems of FEB fusion reactor. The applications during recent six years indicate that it is reasonable and fully admitted by colleagues abroad. Some creative papers with new concept are published. For instance, we first time pointed out a new phenomenon of ＂tritium well depth and tritium well time＂ during the fusion reactor start-up phase. This is somewhat similar to, but quite different from the ＂iodine well depth and iodine well time＂ poisoning problem during restart-up process of a fission reactor. The authors not only proposed but also numerically solved this new phenomenon. The combination of the SWITRIM code package, user＇s guide, and application example are briefly introduced in this article.

Use of Polypropylene Non-woven as Sorbent of Oil Small

In this work, the mechanical tensile and elongation properties and the non-woven polypropylene flammability were evaluated, with variations of gratings, compared to non-woven fabrics prepared with thermo film and TNT （fabric non-fabric）, for applications such as geotextile sorption of oil spills. The results showed high values of tensile strength for non-woven fabric prepared for application as geotextile, improving the mechanical properties of rupture.

Bag-of-visual-words model for artificial pornographic images recognition

It is illegal to spread and transmit pornographic images over internet,either in real or in artificial format.The traditional methods are designed to identify real pornographic images and they are less efficient in dealing with artificial images.Therefore,criminals turn to release artificial pornographic images in some specific scenes,e.g.,in social networks.To efficiently identify artificial pornographic images,a novel bag-of-visual-words based approach is proposed in the work.In the bag-of-words(Bo W)framework,speeded-up robust feature(SURF)is adopted for feature extraction at first,then a visual vocabulary is constructed through K-means clustering and images are represented by an improved Bo W encoding method,and finally the visual words are fed into a learning machine for training and classification.Different from the traditional BoW method,the proposed method sets a weight on each visual word according to the number of features that each cluster contains.Moreover,a non-binary encoding method and cross-matching strategy are utilized to improve the discriminative power of the visual words.Experimental results indicate that the proposed method outperforms the traditional method.

Cloning,characterization,and expression analysis of the DEAD-box family genes,Fc-vasa and Fc-PL10a,in Chinese shrimp (Fenneropenaeus chinensis)

RNA helicases of the DEAD-box and related families are involved in various cellular processes including DNA replication, DNA repair, and RNA processing. However, the function of DEAD-box proteins in aquaculture species is poorly understood at molecular level. We obtained the full-length cDNA sequences of two genes encoding helicase-related proteins, Fc-vasa and Fc-PL10a, from the testes of Chinese shrimp, Fenneropenaeus chinensis. The two predicted amino acid sequences contain all the conserved motifs characterized by the DEAD-box family and several RGG repeats in the N-terminal regions. Homology and phylogenetic analyses indicate that they belong to the vasa and PLIO subfamilies. The three-dimensional structures of the two proteins were predicted with a homology modeling approach. Both core proteins consist of two tandem RecA-like domains similar to those of the DEAD-box RNA helicase. Using reverse transcription-polymerase chain reaction （RT-PCR） and real-time PCR we found that Fc-vasa was expressed specifically in the adult gonads. Transcription decreased in the ovary but increased in the testis during gonadal development. Fc-PL10a expression was widely distributed in the tissues we examined. Using in situ hybridization, we demonstrated that the Fc-vasa transcript is localized to the cytoplasm of the spermatogonia and oocytes. Thus, our results suggest that Fc-wasa plays an important role in germ-line development, and has utility as a germ cell lineage marker which will help to generate new insight into the origin and differentiation of germ cells as well as the regulation of reproduction in F. chinensis.

The next generation of cancer management

As readers of Cancer Biology and Medicine well know,there has been a seismic shift in human molecular biology over the past few years,as momentous in its own way as the discovery of the double-helical structure of DNA by Watson and Crick 60 years ago,the elucidation of the genetic code shortly thereafter,the advent of recombinant DNA and gene cloningin the 1970s, and the introduction of the polymerase chain reaction in the mid-1980s.

基于Wasserstein测度的概率犹豫模糊聚类方法

研究概率犹豫模糊距离测度及其聚类应用。针对现有概率犹豫模糊距离缺陷,如不满足距离的公理化定义、需对元素个数较少的概率犹豫模糊元进行扩充等,提出一种新的距离测度,应用于概率犹豫模糊信息聚类分析中。首先,考虑到Wasserstein距离可以度量概率分布之间的距离,将其引入到概率犹豫模糊环境下,定义了新的概率犹豫模糊距离及相似度公式。其次,运用新的相似度,提出一种改进的概率犹豫模糊聚类算法——概率犹豫模糊编网法,以解决现有概率犹豫模糊信息聚类结果不够精细的问题。最后,通过对钢铁企业聚类的实例验证所提方法的有效性和可行性。

Benzene containing polyhydroxyalkanoates homo-and copolymers synthesized by genome edited Pseudomonas entomophila

Microbial synthesis of functional polymers has become increasingly important for industrial biotechnology. For the first time, it became possible to synthesize controllable composition of poly（3-hydroxyalkanoate） （P3HA） consisting of 3-hydroxydodec- anoate （3HDD） and phenyl group on the side-chain when chromosome of Pseudomonas entomophila was edited to weaken its t-oxidation. Cultured in the presence of 5-phenylvaleric acid （PVA）, the edited P. entomophila produced only homopolymer poly（3-hydroxy-5-phenylvalerate） or P（3HPhV）. While copolyesters P（3HPhV-co-3HDD） of 3-hydroxy-5-phenylvalerate （3HPhV） and 3-hydroxydodecanoate （3HDD） were synthesized when the strain was grown on mixtures of PVA and dodecanoic acid （DDA）. Compositions of 3HPhV in P（3HPhV-co-3HDD） were controllable ranging from 3% to 32% depending on DDDA/PVA ratios. Nuclear magnetic resonance （NMR） spectra clearly indicated that the polymers were homopolymer of P（3HPhV） and random copolymers of 3HPhV and 3HDD. Their mechanical and thermal properties varied dramatically de- pending on the monomer ratios. Our results demonstrated the possibility to produce tailor-made, novel functional PHA using the chromosome edited P. entomophila.