Recently, network coding has been applied to the loss recovery of reliable broadcast transmission in wireless networks. Since it was proved that fi nding the optimal set of lost packets for XOR-ing is a complex NP-com...Recently, network coding has been applied to the loss recovery of reliable broadcast transmission in wireless networks. Since it was proved that fi nding the optimal set of lost packets for XOR-ing is a complex NP-complete problem, the available time-based retransmission scheme and its enhanced retransmission scheme have exponential computational complexity and thus are not scalable to large networks. In this paper, we present an efficient heuristic scheme based on hypergraph coloring and also its enhanced heuristic scheme to improve the transmission efficiency. Basically, our proposed schemes fi rst create a hypergraph according to the packet-loss matrix. Then our schemes solve the problem of generating XORed packets by coloring the edges of hypergraph. Extensive simulation results demonstrate that, the heuristic scheme based on hypergraph coloring and its enhanced scheme can achieve almost the same transmission efficiency as the available ones, but have much lower computational complexity, which is very important for the wireless devices without high computation capacity.展开更多
AIM： To evaluate whether intratumoral injection of liposome-endostatin complexes could enhance the antitumor efficacy of radiation theapy in human liver cardnoma （BEL7402） model.METHODS： Recombinant plasmid pcDNA3...AIM： To evaluate whether intratumoral injection of liposome-endostatin complexes could enhance the antitumor efficacy of radiation theapy in human liver cardnoma （BEL7402） model.METHODS： Recombinant plasmid pcDNA3.End was transfected into human liver carcinoma cell line （BEL7402） with lipofectamine to produce conditioned medium. Then BEL7402 cells and human umbilical vein endothelial cells （HUVECs） were treated with the conditioned medium. Cell cycle and apoptosis were analyzed by flow cytometer and endothelial cell proliferation rates were determined by MTT assay. The antitumor efficacy of endostatin gene combined with ionizing radiation in mouse xenograft liver tumor was observed.RESULTS： Endostatin significantly suppressed the S phase fraction and increased the apoptotic index in HUVECs. In contrast, endostatin treatment had no effect on BEL7402 cell apoptosis （2.1±0.3% vs 8.9±1.3%, t= 8.83, P= 0.009〈0.01） or cell cycle distribution （17.2±2.3% vs 9.8±1.2%, t = 4.94,P = 0.016〈0.05）. The MTT assay showed that endostatin significantly inhibited the proliferation of HUVECs by 46.4%. The combination of local endostatin gene therapy with radiation therapy significantly inhibited the growth of human liver carcinoma BEL7402 xenografts, the inhibition rate of tumor size was 69.8% on d 28 compared to the untreated group. The tumor volume in the pcDNA3.End combined with radiation therapy group （249±83 mm^3） was significantly different from that in the untreated group （823±148 mm^3, t= 5.86, P= 0.009〈0.01） or in the pcDNA3 group （717±94 mm^3, t= 6.46, P= 0.003〈0.01）. Endostatin or the radiation alone also inhibited the growth of liver tumor in vivo, but their inhibition effects were weaker than those of endostatin combined with radiation, the inhibition rates on d 28 were 44.7% and 40.1%, respectively.CONCLUSION： Endostatin not only significantly suppresses tumor growth but also enhances the antitumor efficacy of radiation therapy in human carcinoma xenograft.展开更多
Based on flexible pneumatic actuator(FPA),bending joint and side-sway joint,a new kind of pneumatic dexterous robot finger was developed.The finger is equipped with one five-component force sensor and four contactless...Based on flexible pneumatic actuator(FPA),bending joint and side-sway joint,a new kind of pneumatic dexterous robot finger was developed.The finger is equipped with one five-component force sensor and four contactless magnetic rotary encoders.Mechanical parts and FPAs are integrated,which reduces the overall size of the finger.Driven by FPA directly,the joint output torque is more accurate and the friction and vibration can be effectively reduced.An improved adaptive genetic algorithm(IAGA) was adopted to solve the inverse kinematics problem of the redundant finger.The statics of the finger was analyzed and the relation between fingertip force and joint torque was built.Finally,the finger force/position control principle was introduced.Tracking experiments of fingertip force/position were carried out.The experimental results show that the fingertip position tracking error is within ±1 mm and the fingertip force tracking error is within ±0.4 N.It is also concluded from the theoretical and experimental results that the finger can be controlled and it has a good application prospect.展开更多
In order to obtain coding gain along with diversity gain,rotation code was applied to cooperative diversity employing decoded-and-forward cooperative protocol.Different from the same two symbols transmitted in convent...In order to obtain coding gain along with diversity gain,rotation code was applied to cooperative diversity employing decoded-and-forward cooperative protocol.Different from the same two symbols transmitted in conventional repetition-coded scheme,two different symbols were transmitted separately in two successive timeslots in the proposed rotation-coded cooperative diversity.In this way,constellation spread in the available two-dimensional signal space rather than on a single-dimensional line in repetition-coded scheme,which was supposed to be responsible for the additional coding gain.Under the proposed cooperative transmission model,upper bounds for the symbol-error-rate(SER)of cooperative diversity based on repetition code and rotation code were derived respectively.Both analytical and simulated results show that cooperative diversity based on rotation code can obtain an improved coding gain(by about 2 dB)than repetition-coded scheme without the expense of power or bandwidth.展开更多
A novel optical-spectrum-encoded （OSE） analog-to-digital converter （ADC） is proposed in this letter. To simply exemplify the conversion idea, a 5-bit device structure consisted of Fabry-Perot interferometers （FPI...A novel optical-spectrum-encoded （OSE） analog-to-digital converter （ADC） is proposed in this letter. To simply exemplify the conversion idea, a 5-bit device structure consisted of Fabry-Perot interferometers （FPI） is analyzed and numericaly simulated. The dependence of peak-transmission wavelength on modulation voltage in an electro-optical FPI and the dependence of transmitted power on incident light wavelength in an FPI are discussed and utilized to implement OSEADC. A linearly tunable mode-locked laser, as a voltage-wavelength transformer and a sampler, and chirped grating FPIs, as an encoder array, can be used to obtain much greater sampling rate and bit-resolution.展开更多
Based on an analysis of the characteristics of the Forest Resources Management Information System of each development phase, and consideration of the technical trend in Geographic Information System (GIS) in the Inter...Based on an analysis of the characteristics of the Forest Resources Management Information System of each development phase, and consideration of the technical trend in Geographic Information System (GIS) in the Internet Age, this paper explores the importance and the feasibility of setting up Forest Resources Management Information System based on the WEBGIS. At the same time, based on the experience of our study, the paper explores the function, structure and method of developing the Forest Resources Management Information System based on WEBGIS. With the technology of WEBGIS, the Forest Resources Management Information System with data from Huoditang Farm was set up, which makes a great impact on forest resources management. So setting up the Forest Resources Management Information System based on WEBGIS is a trend of forest resources management. In the course of setting up this system, we must pay attention to following questions: 1) unify data standard and information encoding; 2) change mind.展开更多
A single mammalian transcript normally encodes one protein, but the transcript of GNAS （G-protein u-subunit） contains two reading frames and produces two structurally unrelated proteins, XLas and ALEX. No other conf...A single mammalian transcript normally encodes one protein, but the transcript of GNAS （G-protein u-subunit） contains two reading frames and produces two structurally unrelated proteins, XLas and ALEX. No other confirmed GNAS-Iike dual-coding transcripts have been reported to date, even though many such candidate genes have been predicted by bioinformatics analysis. In this study, we constructed a series of vectors to test how two protein products were translated from a single transcript in vitro. The length of the ORF （open reading frame）, position of the first AUG and the Kozak motif were found to be important factors. These factors, as well as 55-bp NMD （nonsense-mediated mRNA decay） rule, were used in a bioinformatics search for candidate dual-coding transcripts. A total of 1307, 750 and 474 two-ORF-containing transcripts were found in human, mouse and rat, respectively, of which 170, 89 and 70, respectively, were found to be potential dual-coding transcripts. Most transcripts showed low conservation among species. Interestingly, dual-coding transcripts were significantly enriched for transcripts from the zinc-finger protein family, which are usually DNA-binding proteins involved in regulation of the transcription process.展开更多
基金supported by the National Natural Science Foundation of China (60502046, 60573034)863 Foundation of China (2007AA01Z215)
文摘Recently, network coding has been applied to the loss recovery of reliable broadcast transmission in wireless networks. Since it was proved that fi nding the optimal set of lost packets for XOR-ing is a complex NP-complete problem, the available time-based retransmission scheme and its enhanced retransmission scheme have exponential computational complexity and thus are not scalable to large networks. In this paper, we present an efficient heuristic scheme based on hypergraph coloring and also its enhanced heuristic scheme to improve the transmission efficiency. Basically, our proposed schemes fi rst create a hypergraph according to the packet-loss matrix. Then our schemes solve the problem of generating XORed packets by coloring the edges of hypergraph. Extensive simulation results demonstrate that, the heuristic scheme based on hypergraph coloring and its enhanced scheme can achieve almost the same transmission efficiency as the available ones, but have much lower computational complexity, which is very important for the wireless devices without high computation capacity.
文摘AIM： To evaluate whether intratumoral injection of liposome-endostatin complexes could enhance the antitumor efficacy of radiation theapy in human liver cardnoma （BEL7402） model.METHODS： Recombinant plasmid pcDNA3.End was transfected into human liver carcinoma cell line （BEL7402） with lipofectamine to produce conditioned medium. Then BEL7402 cells and human umbilical vein endothelial cells （HUVECs） were treated with the conditioned medium. Cell cycle and apoptosis were analyzed by flow cytometer and endothelial cell proliferation rates were determined by MTT assay. The antitumor efficacy of endostatin gene combined with ionizing radiation in mouse xenograft liver tumor was observed.RESULTS： Endostatin significantly suppressed the S phase fraction and increased the apoptotic index in HUVECs. In contrast, endostatin treatment had no effect on BEL7402 cell apoptosis （2.1±0.3% vs 8.9±1.3%, t= 8.83, P= 0.009〈0.01） or cell cycle distribution （17.2±2.3% vs 9.8±1.2%, t = 4.94,P = 0.016〈0.05）. The MTT assay showed that endostatin significantly inhibited the proliferation of HUVECs by 46.4%. The combination of local endostatin gene therapy with radiation therapy significantly inhibited the growth of human liver carcinoma BEL7402 xenografts, the inhibition rate of tumor size was 69.8% on d 28 compared to the untreated group. The tumor volume in the pcDNA3.End combined with radiation therapy group （249±83 mm^3） was significantly different from that in the untreated group （823±148 mm^3, t= 5.86, P= 0.009〈0.01） or in the pcDNA3 group （717±94 mm^3, t= 6.46, P= 0.003〈0.01）. Endostatin or the radiation alone also inhibited the growth of liver tumor in vivo, but their inhibition effects were weaker than those of endostatin combined with radiation, the inhibition rates on d 28 were 44.7% and 40.1%, respectively.CONCLUSION： Endostatin not only significantly suppresses tumor growth but also enhances the antitumor efficacy of radiation therapy in human carcinoma xenograft.
基金Project(2009AA04Z209) supported by the National High Technology Research and Development Program of ChinaProject(R1090674) supported by the Natural Science Foundation of Zhejiang Province,ChinaProject(51075363) supported by the National Natural Science Foundation of China
文摘Based on flexible pneumatic actuator(FPA),bending joint and side-sway joint,a new kind of pneumatic dexterous robot finger was developed.The finger is equipped with one five-component force sensor and four contactless magnetic rotary encoders.Mechanical parts and FPAs are integrated,which reduces the overall size of the finger.Driven by FPA directly,the joint output torque is more accurate and the friction and vibration can be effectively reduced.An improved adaptive genetic algorithm(IAGA) was adopted to solve the inverse kinematics problem of the redundant finger.The statics of the finger was analyzed and the relation between fingertip force and joint torque was built.Finally,the finger force/position control principle was introduced.Tracking experiments of fingertip force/position were carried out.The experimental results show that the fingertip position tracking error is within ±1 mm and the fingertip force tracking error is within ±0.4 N.It is also concluded from the theoretical and experimental results that the finger can be controlled and it has a good application prospect.
基金Project(2006AA01Z270)supported by the National High Technology Research and Development Program of ChinaProject(U0635003)supported by the National Natural Science Foundation of Guangdong Province,ChinaProject(2007F07)supported by the National Science Foundation of Shaanxi Province,China
文摘In order to obtain coding gain along with diversity gain,rotation code was applied to cooperative diversity employing decoded-and-forward cooperative protocol.Different from the same two symbols transmitted in conventional repetition-coded scheme,two different symbols were transmitted separately in two successive timeslots in the proposed rotation-coded cooperative diversity.In this way,constellation spread in the available two-dimensional signal space rather than on a single-dimensional line in repetition-coded scheme,which was supposed to be responsible for the additional coding gain.Under the proposed cooperative transmission model,upper bounds for the symbol-error-rate(SER)of cooperative diversity based on repetition code and rotation code were derived respectively.Both analytical and simulated results show that cooperative diversity based on rotation code can obtain an improved coding gain(by about 2 dB)than repetition-coded scheme without the expense of power or bandwidth.
文摘A novel optical-spectrum-encoded （OSE） analog-to-digital converter （ADC） is proposed in this letter. To simply exemplify the conversion idea, a 5-bit device structure consisted of Fabry-Perot interferometers （FPI） is analyzed and numericaly simulated. The dependence of peak-transmission wavelength on modulation voltage in an electro-optical FPI and the dependence of transmitted power on incident light wavelength in an FPI are discussed and utilized to implement OSEADC. A linearly tunable mode-locked laser, as a voltage-wavelength transformer and a sampler, and chirped grating FPIs, as an encoder array, can be used to obtain much greater sampling rate and bit-resolution.
文摘Based on an analysis of the characteristics of the Forest Resources Management Information System of each development phase, and consideration of the technical trend in Geographic Information System (GIS) in the Internet Age, this paper explores the importance and the feasibility of setting up Forest Resources Management Information System based on the WEBGIS. At the same time, based on the experience of our study, the paper explores the function, structure and method of developing the Forest Resources Management Information System based on WEBGIS. With the technology of WEBGIS, the Forest Resources Management Information System with data from Huoditang Farm was set up, which makes a great impact on forest resources management. So setting up the Forest Resources Management Information System based on WEBGIS is a trend of forest resources management. In the course of setting up this system, we must pay attention to following questions: 1) unify data standard and information encoding; 2) change mind.
文摘A single mammalian transcript normally encodes one protein, but the transcript of GNAS （G-protein u-subunit） contains two reading frames and produces two structurally unrelated proteins, XLas and ALEX. No other confirmed GNAS-Iike dual-coding transcripts have been reported to date, even though many such candidate genes have been predicted by bioinformatics analysis. In this study, we constructed a series of vectors to test how two protein products were translated from a single transcript in vitro. The length of the ORF （open reading frame）, position of the first AUG and the Kozak motif were found to be important factors. These factors, as well as 55-bp NMD （nonsense-mediated mRNA decay） rule, were used in a bioinformatics search for candidate dual-coding transcripts. A total of 1307, 750 and 474 two-ORF-containing transcripts were found in human, mouse and rat, respectively, of which 170, 89 and 70, respectively, were found to be potential dual-coding transcripts. Most transcripts showed low conservation among species. Interestingly, dual-coding transcripts were significantly enriched for transcripts from the zinc-finger protein family, which are usually DNA-binding proteins involved in regulation of the transcription process.
