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2-巯基-6-羟基-4,5-二氨基嘧啶的合成改进 被引量:2
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作者 孙学芹 陶晓春 《化学研究与应用》 CAS CSCD 北大核心 2001年第6期701-702,共2页
Synthesis steps of 4,5 diamino 6 hydroxy 2 mercaptopyrimidine were improved on cyclocondensation of ethyl cyanoacetate with thiourea,nitrosation and reduction to obtain the product in 89% yield with high purity on ind... Synthesis steps of 4,5 diamino 6 hydroxy 2 mercaptopyrimidine were improved on cyclocondensation of ethyl cyanoacetate with thiourea,nitrosation and reduction to obtain the product in 89% yield with high purity on industrial scale. 展开更多
关键词 合成 缩和环化 2-巯基-6-羟基-4 5-二氨基嘧啶 医药中间体 工艺改进
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