Pruritis with abnormal liver function tests is the classical presentation of intrahepatic cholestasis of pregnancy(ICP),a condition associated with significant fetal complications.Although the etiology of ICP is uncle...Pruritis with abnormal liver function tests is the classical presentation of intrahepatic cholestasis of pregnancy(ICP),a condition associated with significant fetal complications.Although the etiology of ICP is unclear in many cases,certain features of the clinical presentation should alert the practitioner to the possibility of an underlying metabolic defect, which may not only affect subsequent pregnancies, but may be an indicator of more serious subsequent liver disease.We report a kindred of Anglo-Celtic descent,among whom many members present with ICP,gallstones or cholestasis related to use of oral contraception.Genetic studies revealed a novel mutation in the ABCB4 gene,which codes for a phospholipid transport protein.The clinical significance of this mutation and the importance of identifying such patients are discussed.展开更多
An intelligent camera for surface defect inspection is presented which can pre-process the surface image of a rolled strip and pick defective areas out at a spead of 1 600 meters per minute. The camera is made up of a...An intelligent camera for surface defect inspection is presented which can pre-process the surface image of a rolled strip and pick defective areas out at a spead of 1 600 meters per minute. The camera is made up of a high speed line CCD, a 60 Mb/s CCD digitizer with correlated double sampling function, and a field programmable gate array(FPGA), which can quickly distinguish defective areas using a perceptron embedded in FPGA thus the data to be further processed would dramatically be reduced. Some experiments show that the camera can meet high producing speed, and reduce cost and complexity of automation surface inspection systems.展开更多
文摘Pruritis with abnormal liver function tests is the classical presentation of intrahepatic cholestasis of pregnancy(ICP),a condition associated with significant fetal complications.Although the etiology of ICP is unclear in many cases,certain features of the clinical presentation should alert the practitioner to the possibility of an underlying metabolic defect, which may not only affect subsequent pregnancies, but may be an indicator of more serious subsequent liver disease.We report a kindred of Anglo-Celtic descent,among whom many members present with ICP,gallstones or cholestasis related to use of oral contraception.Genetic studies revealed a novel mutation in the ABCB4 gene,which codes for a phospholipid transport protein.The clinical significance of this mutation and the importance of identifying such patients are discussed.
文摘An intelligent camera for surface defect inspection is presented which can pre-process the surface image of a rolled strip and pick defective areas out at a spead of 1 600 meters per minute. The camera is made up of a high speed line CCD, a 60 Mb/s CCD digitizer with correlated double sampling function, and a field programmable gate array(FPGA), which can quickly distinguish defective areas using a perceptron embedded in FPGA thus the data to be further processed would dramatically be reduced. Some experiments show that the camera can meet high producing speed, and reduce cost and complexity of automation surface inspection systems.
