The invention of the World Wide Web, especially the Web 2.0, originally led some sociologists to believe that this tool would have favoured the creation of a ＂collective intelligence＂ able to spread and increase the...The invention of the World Wide Web, especially the Web 2.0, originally led some sociologists to believe that this tool would have favoured the creation of a ＂collective intelligence＂ able to spread and increase the level of democracy in the society. Nowadays, as a matter of fact, Information and Communications Technologies （ICTs） continue excluding part of the population and contribute to a top-down organisation of the main streams of information neutralising active potentialities and risking, paradoxically, to isolate users who are not aware of the mechanisms of the lnternet. The ＂doxic＂ acceptance of web contents, structures, and tools indeed precludes some kinds of knowledge and some different models of participation, with significant consequences on the social construction of reality. As a result, a tendency emerges towards a virtual-only participation and the click-tivism seems more and more to be turning into a form of slack-tivism.展开更多
lntemet services on bioinformatics still remain a popular tool for the researchers. Here the authors present a recently developed web-site http：//bri-shur.com where several tools and pipelines for protein structure p...lntemet services on bioinformatics still remain a popular tool for the researchers. Here the authors present a recently developed web-site http：//bri-shur.com where several tools and pipelines for protein structure prediction are implemented. The prediction of a structure for a particular protein often requires a sensitive and iterative approach, and the web-site provides an environment for this kind of work. Software that is used in the services includes both free programs available in the Internet and newly developed algorithms. The service on homology screening in PDB for a structure template is implemented using an approach that is alternative to well-known BLAST algorithm and it has some advantages over BLAST. The service on homology modeling uses well-known Nest program. The service on protein energy estimate allows selecting a best template in the set of homologs and adds a functionality of fold recognition to the environment. The design of the site simplifies several of the most useful bioinformatics routines, thus making them available to a large community of researchers. Services are provided free of charge without registration, and the user＇s privacy is taken care of.展开更多
文摘The invention of the World Wide Web, especially the Web 2.0, originally led some sociologists to believe that this tool would have favoured the creation of a ＂collective intelligence＂ able to spread and increase the level of democracy in the society. Nowadays, as a matter of fact, Information and Communications Technologies （ICTs） continue excluding part of the population and contribute to a top-down organisation of the main streams of information neutralising active potentialities and risking, paradoxically, to isolate users who are not aware of the mechanisms of the lnternet. The ＂doxic＂ acceptance of web contents, structures, and tools indeed precludes some kinds of knowledge and some different models of participation, with significant consequences on the social construction of reality. As a result, a tendency emerges towards a virtual-only participation and the click-tivism seems more and more to be turning into a form of slack-tivism.
文摘lntemet services on bioinformatics still remain a popular tool for the researchers. Here the authors present a recently developed web-site http：//bri-shur.com where several tools and pipelines for protein structure prediction are implemented. The prediction of a structure for a particular protein often requires a sensitive and iterative approach, and the web-site provides an environment for this kind of work. Software that is used in the services includes both free programs available in the Internet and newly developed algorithms. The service on homology screening in PDB for a structure template is implemented using an approach that is alternative to well-known BLAST algorithm and it has some advantages over BLAST. The service on homology modeling uses well-known Nest program. The service on protein energy estimate allows selecting a best template in the set of homologs and adds a functionality of fold recognition to the environment. The design of the site simplifies several of the most useful bioinformatics routines, thus making them available to a large community of researchers. Services are provided free of charge without registration, and the user＇s privacy is taken care of.
