目的通过建立非融合技术人工椎间盘(artificial disk of non-fusion technology,ADNFT)的山羊体内模型,研究其喷钛涂层骨长入、固定效果及非融合技术,为临床应用提供可行性证据。方法选择10只成年健康山羊作为实验对象,体重35~55 kg,...目的通过建立非融合技术人工椎间盘(artificial disk of non-fusion technology,ADNFT)的山羊体内模型,研究其喷钛涂层骨长入、固定效果及非融合技术,为临床应用提供可行性证据。方法选择10只成年健康山羊作为实验对象,体重35~55 kg,羊龄10~24个月,随机分成A、B两组,每组各5只,经腰椎前外侧入路,行非融合技术人工椎间盘置换术,A、B组分别在术后3、6个月行腰椎正侧位的影像学检查,并分别在术后3、6个月取出包括假体在内的周围骨组织和软组织,常规制作标本后分别行病理、扫描电镜检查。通过腰椎影像学、病理及扫描电镜评价假体的固定效果、喷钛涂层骨长入及人工椎间盘的活动度。结果 10只山羊均建模成功,术后取出假体及周围组织的病理结果及电镜下可见假体喷钛涂层骨组织长入良好,人工椎间盘的钴铬钼合金、硅胶及喷钛涂层与周围组织相容性良好,腰椎X线片示假体位置良好,无松动,人工椎间盘有一定的活动度。结论非融合技术人工椎间盘的喷钛涂层骨长入良好,与椎体的固定效果可靠,材料的组织相容性好,具有非融合技术的效果。展开更多
The de Sitter special relativity on the Beltrami-de Sitter-spacetime and Snyder's model in the momentum space can be combined together with an IR-UV duality to get the complete Yang model at both classical and quantu...The de Sitter special relativity on the Beltrami-de Sitter-spacetime and Snyder's model in the momentum space can be combined together with an IR-UV duality to get the complete Yang model at both classical and quantum levels, which are related by the proposed Killing quantization. It is actually a special relativity based on the principle of relativity of three universal constants (c, ρp, R).展开更多
This study compares the persistence and histological characteristics of gut suture with those of human amnion collagen, bovine collagen, and Vicryl suture implants in rats. Gut suture and human amnion collagen more re...This study compares the persistence and histological characteristics of gut suture with those of human amnion collagen, bovine collagen, and Vicryl suture implants in rats. Gut suture and human amnion collagen more resembled living tissue than did bovine collagen and were characterized by their cel1ularity and the presence of numerous capillaries. The Vicryl suture implants were quickly absorbed. Picrosirius polarization revealed the synthesis of host collagen by rat fibroblasts which immigrated into the gut suture and human amnion collagen implants. The authors suggest the potential of gut suture as a soft tissue substitute to improve linear skin contour deficits.展开更多
文摘目的通过建立非融合技术人工椎间盘(artificial disk of non-fusion technology,ADNFT)的山羊体内模型,研究其喷钛涂层骨长入、固定效果及非融合技术,为临床应用提供可行性证据。方法选择10只成年健康山羊作为实验对象,体重35~55 kg,羊龄10~24个月,随机分成A、B两组,每组各5只,经腰椎前外侧入路,行非融合技术人工椎间盘置换术,A、B组分别在术后3、6个月行腰椎正侧位的影像学检查,并分别在术后3、6个月取出包括假体在内的周围骨组织和软组织,常规制作标本后分别行病理、扫描电镜检查。通过腰椎影像学、病理及扫描电镜评价假体的固定效果、喷钛涂层骨长入及人工椎间盘的活动度。结果 10只山羊均建模成功,术后取出假体及周围组织的病理结果及电镜下可见假体喷钛涂层骨组织长入良好,人工椎间盘的钴铬钼合金、硅胶及喷钛涂层与周围组织相容性良好,腰椎X线片示假体位置良好,无松动,人工椎间盘有一定的活动度。结论非融合技术人工椎间盘的喷钛涂层骨长入良好,与椎体的固定效果可靠,材料的组织相容性好,具有非融合技术的效果。
基金Supported by the National Natural Science Foundation of China under Grant Nos.10701081,10975167,and 10875129
文摘The de Sitter special relativity on the Beltrami-de Sitter-spacetime and Snyder's model in the momentum space can be combined together with an IR-UV duality to get the complete Yang model at both classical and quantum levels, which are related by the proposed Killing quantization. It is actually a special relativity based on the principle of relativity of three universal constants (c, ρp, R).
文摘This study compares the persistence and histological characteristics of gut suture with those of human amnion collagen, bovine collagen, and Vicryl suture implants in rats. Gut suture and human amnion collagen more resembled living tissue than did bovine collagen and were characterized by their cel1ularity and the presence of numerous capillaries. The Vicryl suture implants were quickly absorbed. Picrosirius polarization revealed the synthesis of host collagen by rat fibroblasts which immigrated into the gut suture and human amnion collagen implants. The authors suggest the potential of gut suture as a soft tissue substitute to improve linear skin contour deficits.