2020年4月,美国发布了美国感染病学会新型冠状病毒肺炎患者治疗及管理指南(Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19)。该文对该指南中儿童相关内容进行解读,包...2020年4月,美国发布了美国感染病学会新型冠状病毒肺炎患者治疗及管理指南(Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19)。该文对该指南中儿童相关内容进行解读,包括COVID19的流行性病学特点、临床表现、诊断/筛查及临床用药等方面,希望对我国儿科同行提高COVID-19的诊断和防治水平有所帮助。展开更多
AIM: To compare the racial differences of anatomical distribution of colorectal cancer (CRC) and determine the association of age, gender and time with anatomical distribution between patients from America (white) and...AIM: To compare the racial differences of anatomical distribution of colorectal cancer (CRC) and determine the association of age, gender and time with anatomical distribution between patients from America (white) and China (oriental).METHODS: Data was collected from 690 consecutive patients in Cleveland Clinic Florida, U.S.A. and 870consecutive patients in Nan Fang Hospital affiliated to the First Military Medical University, China over the past 11years from 1990 to 2000. All patients had colorectal adenocarcinoma diagnosed by histology and underwent surgery.RESULTS: The anatomical subsite distribution of tumor,age and gender were significantly different between white and oriental patients. Lesions in the proximal colon (P＜0.001) were found in 36.3 % of white vs 26.0 % of oriental patients and cancers located in the distal colon and rectum in 63.7 % of white and 74 % of oriental patients (P＜0.001). There was a trend towards the redistribution from distal colon and rectum to proximal colon in white males over time, especially in older patients (＞80 years).No significant change of anatomical distribution occurred in white women and Oriental patients. The mean age at diagnosis was 69.0 years in white patients and 48.3 years in Oriental patients (P＜0.001).CONCLUSION: This is the first study comparing the anatomical distribution of colorectal cancers in whites and Chinese patients. White Americans have a higher risk of proximal CRC and this risk increased with time. The proportion of white males with CRC also increased with time.Chinese patients were more likely to have distal CRC and developed the disease at a significantly earlier age than white patients. These findings have enhanced our understanding of the disease process of colorectal cancer in these two races.展开更多
Depression is not only a major global public health concern,but also a common comorbidity among patients who experience chronic diseases,such as cancer,stroke,heart disease,diabetes,and chronic obstructive pulmonary d...Depression is not only a major global public health concern,but also a common comorbidity among patients who experience chronic diseases,such as cancer,stroke,heart disease,diabetes,and chronic obstructive pulmonary disease.Yet the recognition and treatment varies widely around the world.This study(1)provides an integrated review of the literature on the prevalence of depression among patients with chronic diseases in China and the United States and its relationship to poorer health outcomes and(2)compares the differences in the percentages of patients receiving treatments for depression between the United States and China.Given the current situation,we recommended that primary care and specialty providers should be knowledgeable and alert regarding the signs of depression.Efforts should be directed to further implement integrated care based interventions to manage depression and improve quality of life among patients suffering chronic diseases in both China and the United States.展开更多
文摘2020年4月,美国发布了美国感染病学会新型冠状病毒肺炎患者治疗及管理指南(Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19)。该文对该指南中儿童相关内容进行解读,包括COVID19的流行性病学特点、临床表现、诊断/筛查及临床用药等方面,希望对我国儿科同行提高COVID-19的诊断和防治水平有所帮助。
文摘AIM: To compare the racial differences of anatomical distribution of colorectal cancer (CRC) and determine the association of age, gender and time with anatomical distribution between patients from America (white) and China (oriental).METHODS: Data was collected from 690 consecutive patients in Cleveland Clinic Florida, U.S.A. and 870consecutive patients in Nan Fang Hospital affiliated to the First Military Medical University, China over the past 11years from 1990 to 2000. All patients had colorectal adenocarcinoma diagnosed by histology and underwent surgery.RESULTS: The anatomical subsite distribution of tumor,age and gender were significantly different between white and oriental patients. Lesions in the proximal colon (P＜0.001) were found in 36.3 % of white vs 26.0 % of oriental patients and cancers located in the distal colon and rectum in 63.7 % of white and 74 % of oriental patients (P＜0.001). There was a trend towards the redistribution from distal colon and rectum to proximal colon in white males over time, especially in older patients (＞80 years).No significant change of anatomical distribution occurred in white women and Oriental patients. The mean age at diagnosis was 69.0 years in white patients and 48.3 years in Oriental patients (P＜0.001).CONCLUSION: This is the first study comparing the anatomical distribution of colorectal cancers in whites and Chinese patients. White Americans have a higher risk of proximal CRC and this risk increased with time. The proportion of white males with CRC also increased with time.Chinese patients were more likely to have distal CRC and developed the disease at a significantly earlier age than white patients. These findings have enhanced our understanding of the disease process of colorectal cancer in these two races.
基金This research received no specific grant from any funding agency in the public,commercial or not-for-profit sectors
文摘Depression is not only a major global public health concern,but also a common comorbidity among patients who experience chronic diseases,such as cancer,stroke,heart disease,diabetes,and chronic obstructive pulmonary disease.Yet the recognition and treatment varies widely around the world.This study(1)provides an integrated review of the literature on the prevalence of depression among patients with chronic diseases in China and the United States and its relationship to poorer health outcomes and(2)compares the differences in the percentages of patients receiving treatments for depression between the United States and China.Given the current situation,we recommended that primary care and specialty providers should be knowledgeable and alert regarding the signs of depression.Efforts should be directed to further implement integrated care based interventions to manage depression and improve quality of life among patients suffering chronic diseases in both China and the United States.
