目的 研究美花铁线莲茎70%乙醇提取物正丁醇萃取部位的化学成分。方法 采用热回流法进行提取,对提取物的正丁醇萃取部位进行分离;运用多种分离手段包括正相硅胶、ODS反相硅胶、Sephadex LH-20凝胶柱色谱以及半制备高效液相色谱等进行分...目的 研究美花铁线莲茎70%乙醇提取物正丁醇萃取部位的化学成分。方法 采用热回流法进行提取,对提取物的正丁醇萃取部位进行分离;运用多种分离手段包括正相硅胶、ODS反相硅胶、Sephadex LH-20凝胶柱色谱以及半制备高效液相色谱等进行分离纯化;对单体化合物进行核磁共振和质谱检测,根据波谱数据(1D-NMR、2D-NMR及MS)和理化性质进行结构鉴定。结果 分离得到4个三萜类、3个木脂素类和1个甾醇苷类化合物,分别鉴定为木栓酮(1)、表木栓醇(2)、β-胡萝卜苷(3)、sargentodoside D (4)、落叶松脂醇-4,4’-二-O-β-D-吡喃葡萄糖苷(5)、落叶松脂醇-4-O-β-D-吡喃葡萄糖苷(6)、sieboldnoside A (7)和huzhangoside C (8)。结论 所有化合物均为首次从本植物中分离得到,化合物4为首次从铁线莲属植物中发现。展开更多
In the research, trees along 42 roads in Chongqing were explored and es- timated in terms of aesthetics, and aesthetic tendency and major influential factors of aesthetic value of street greenbelts in Chongqing arteri...In the research, trees along 42 roads in Chongqing were explored and es- timated in terms of aesthetics, and aesthetic tendency and major influential factors of aesthetic value of street greenbelts in Chongqing arterial roads were estimated with phychophysical method to establish SBE model of arterial road greenbelts land- scape.展开更多
The garden aesthetics is incorporated by landscape architecture, as well as a branch of aesthetics. The beauty of gardens is shown in a variety of forms, with varied connotations. According to garden design requiremen...The garden aesthetics is incorporated by landscape architecture, as well as a branch of aesthetics. The beauty of gardens is shown in a variety of forms, with varied connotations. According to garden design requirements and linear char- acters, the research reviewed concept and extended meaning of lines, curves, and natural lines for better apprehension of garden linear beauty.展开更多
Video sensors and agricultural IoT(internet of things) have been widely used in the informationalized orchards.In order to realize intelligent-unattended early warning for disease-pest,this paper presents convolutiona...Video sensors and agricultural IoT(internet of things) have been widely used in the informationalized orchards.In order to realize intelligent-unattended early warning for disease-pest,this paper presents convolutional neural network(CNN) early warning for apple skin lesion image,which is real-time acquired by infrared video sensor.More specifically,as to skin lesion image,a suite of processing methods is devised to simulate the disturbance of variable orientation and light condition which occurs in orchards.It designs a method to recognize apple pathologic images based on CNN,and formulates a self-adaptive momentum rule to update CNN parameters.For example,a series of experiments are carried out on the recognition of fruit lesion image of apple trees for early warning.The results demonstrate that compared with the shallow learning algorithms and other involved,wellknown deep learning methods,the recognition accuracy of the proposal is up to 96.08%,with a fairly quick convergence,and it also presents satisfying smoothness and stableness after convergence.In addition,statistics on different benchmark datasets prove that it is fairly effective to other image patterns concerned.展开更多
Background There were limited data comparing the major clinical outcomes between first-generation （1G）-drug eluting stentts （DES） and second-generation （2G）-DES in patients with acute myocardial infarction （AMI...Background There were limited data comparing the major clinical outcomes between first-generation （1G）-drug eluting stentts （DES） and second-generation （2G）-DES in patients with acute myocardial infarction （AMI） after percutaneous coronary intervention （PCI） during very long follow-up periods. We thought to investigate the comparative efficacy and safety of 2G-DES compared with 1G-DES in AMI patients during 5-year follow-up periods. Method A total of 1016 eligible AMI patients who underwent PCI with 1G-DES [paclitaxel-, sirolimus-, 1G-zotarolimus-eluting stent （endeavor~ or endeavor sprintS）, n = 554] or 2G-DES [2G-zotarolimus （endeavor resolute~）- or everolimus-eluting stent, n = 462] were enrolled. The primary endpoint was the occurrence of major adverse cardiac events （MACE） defined as total death, non-fatal myocardial infarction （MI）, target lesion revascularization （TLR）, target vessel revascularization （TVR）, non-target vessel revascularization （Non-TVR） and the secondary endpoint was stem thrombosis （ST） at 5 years. Results Two propensity score-ma- tched （PSM） groups （232 pairs, n = 464, C-statistic = 0.802） were generated. During the 5-year follow-up period, the cumulative incidence of TLR [hazard ratio （HR）： 3.133; 95% confidence interval （CI）： 1.539-6.376; P = 0.002], TVR （HR： 3.144; 95% CI： 1.59645.192; P = 0.001） and total revascularization rate （FIR： 1.874; 95% CI： 1.086-3.140; P = 0.023） were significantly higher in 1G-DES compared with 2G-DES after PSM. However, the incidence of total death, non-fatal MI and ST were similar between the two groups. Conclusion In this single-center and all-comers registry, 2G-DES＇s superiorities for TLR, TVP, and total revascularization in AMI patients suggested during 5-year clinical follow-up periods.展开更多
In accordance to Langerian aesthetic theory, Mark Campbell （1992） concludes that Cage＇s 4 33＂ （1952） is by no means aesthetic music. I argue the antithesis： Cage＇s 433＂ satisfies Langerian aesthetic theory, a...In accordance to Langerian aesthetic theory, Mark Campbell （1992） concludes that Cage＇s 4 33＂ （1952） is by no means aesthetic music. I argue the antithesis： Cage＇s 433＂ satisfies Langerian aesthetic theory, and is indeed ＂aesthetic＂ music. Cage does something more： he satisfies Langerian aesthetic theory, yet he is not limited by it. He does not simply create music, nor does he offer listeners a musical space. He creates what Gilles Deleuze and Fe1ix Guattari （1987） call a line of becoming that passes between music making and a musical space. In 4 minutes and 33 seconds of silence, Cage presents a sense of emptiness and numbness felt simultaneously with fullness and explosion. In what appears to be stillness, the listener experiences the flux of movement; what appears to be devoid of depth, is filled with complexities. 433＂ embraces chance, uncertainty, and the unknown; it is an experimental process; it is becoming-music in 4 minutes and 33 seconds.展开更多
It is well known that the ocular contour was characterized by its skin structure relevant to fillings of soft tissue and concave-convex bones. With aging, it changed a lot due to the volume loss of soft tissue. In rec...It is well known that the ocular contour was characterized by its skin structure relevant to fillings of soft tissue and concave-convex bones. With aging, it changed a lot due to the volume loss of soft tissue. In recent studies, the aging process of the Asians whose eyelids flled with more soft tissue had signifcant impacts on the ocular contour. The aim of our work was to investigate the changes of the ocular contour of Asian people and establish a curve to describe it. In this study, it was demonstrated that the aging was not only linked to the distance between the inferior border of palpebral bag and the midpoint of palpebral fissure, but also correlated with the angle between palpebral fissure and the facial midline. Therefore, “Youthful Curve of Ocular Region” was established with measurements based on mentioned two areas. This curve went through the regions of upper and lower eyelid area and palpebral bags area. In addition, by using multivariate linear regression, a mathematical model to analyze this curve was obtained. The mathematical model was a crucial supplement to evaluate appearance age of ocular region in Asian people. Moreover, it had great potential in developments of anti-aging effects of eye cosmetics.展开更多
文摘目的 研究美花铁线莲茎70%乙醇提取物正丁醇萃取部位的化学成分。方法 采用热回流法进行提取,对提取物的正丁醇萃取部位进行分离;运用多种分离手段包括正相硅胶、ODS反相硅胶、Sephadex LH-20凝胶柱色谱以及半制备高效液相色谱等进行分离纯化;对单体化合物进行核磁共振和质谱检测,根据波谱数据(1D-NMR、2D-NMR及MS)和理化性质进行结构鉴定。结果 分离得到4个三萜类、3个木脂素类和1个甾醇苷类化合物,分别鉴定为木栓酮(1)、表木栓醇(2)、β-胡萝卜苷(3)、sargentodoside D (4)、落叶松脂醇-4,4’-二-O-β-D-吡喃葡萄糖苷(5)、落叶松脂醇-4-O-β-D-吡喃葡萄糖苷(6)、sieboldnoside A (7)和huzhangoside C (8)。结论 所有化合物均为首次从本植物中分离得到,化合物4为首次从铁线莲属植物中发现。
文摘In the research, trees along 42 roads in Chongqing were explored and es- timated in terms of aesthetics, and aesthetic tendency and major influential factors of aesthetic value of street greenbelts in Chongqing arterial roads were estimated with phychophysical method to establish SBE model of arterial road greenbelts land- scape.
基金Supported by Humanities and Social Sciences Project of Jiangxi Higher Education Institutions(GL1436)~~
文摘The garden aesthetics is incorporated by landscape architecture, as well as a branch of aesthetics. The beauty of gardens is shown in a variety of forms, with varied connotations. According to garden design requirements and linear char- acters, the research reviewed concept and extended meaning of lines, curves, and natural lines for better apprehension of garden linear beauty.
基金Supported by the National Natural Science Foundation of China(No.61271257)Beijing National Science Foundation(No.4151001)Hunan Education Department Project(No.16A131)
文摘Video sensors and agricultural IoT(internet of things) have been widely used in the informationalized orchards.In order to realize intelligent-unattended early warning for disease-pest,this paper presents convolutional neural network(CNN) early warning for apple skin lesion image,which is real-time acquired by infrared video sensor.More specifically,as to skin lesion image,a suite of processing methods is devised to simulate the disturbance of variable orientation and light condition which occurs in orchards.It designs a method to recognize apple pathologic images based on CNN,and formulates a self-adaptive momentum rule to update CNN parameters.For example,a series of experiments are carried out on the recognition of fruit lesion image of apple trees for early warning.The results demonstrate that compared with the shallow learning algorithms and other involved,wellknown deep learning methods,the recognition accuracy of the proposal is up to 96.08%,with a fairly quick convergence,and it also presents satisfying smoothness and stableness after convergence.In addition,statistics on different benchmark datasets prove that it is fairly effective to other image patterns concerned.
文摘Background There were limited data comparing the major clinical outcomes between first-generation （1G）-drug eluting stentts （DES） and second-generation （2G）-DES in patients with acute myocardial infarction （AMI） after percutaneous coronary intervention （PCI） during very long follow-up periods. We thought to investigate the comparative efficacy and safety of 2G-DES compared with 1G-DES in AMI patients during 5-year follow-up periods. Method A total of 1016 eligible AMI patients who underwent PCI with 1G-DES [paclitaxel-, sirolimus-, 1G-zotarolimus-eluting stent （endeavor~ or endeavor sprintS）, n = 554] or 2G-DES [2G-zotarolimus （endeavor resolute~）- or everolimus-eluting stent, n = 462] were enrolled. The primary endpoint was the occurrence of major adverse cardiac events （MACE） defined as total death, non-fatal myocardial infarction （MI）, target lesion revascularization （TLR）, target vessel revascularization （TVR）, non-target vessel revascularization （Non-TVR） and the secondary endpoint was stem thrombosis （ST） at 5 years. Results Two propensity score-ma- tched （PSM） groups （232 pairs, n = 464, C-statistic = 0.802） were generated. During the 5-year follow-up period, the cumulative incidence of TLR [hazard ratio （HR）： 3.133; 95% confidence interval （CI）： 1.539-6.376; P = 0.002], TVR （HR： 3.144; 95% CI： 1.59645.192; P = 0.001） and total revascularization rate （FIR： 1.874; 95% CI： 1.086-3.140; P = 0.023） were significantly higher in 1G-DES compared with 2G-DES after PSM. However, the incidence of total death, non-fatal MI and ST were similar between the two groups. Conclusion In this single-center and all-comers registry, 2G-DES＇s superiorities for TLR, TVP, and total revascularization in AMI patients suggested during 5-year clinical follow-up periods.
文摘In accordance to Langerian aesthetic theory, Mark Campbell （1992） concludes that Cage＇s 4 33＂ （1952） is by no means aesthetic music. I argue the antithesis： Cage＇s 433＂ satisfies Langerian aesthetic theory, and is indeed ＂aesthetic＂ music. Cage does something more： he satisfies Langerian aesthetic theory, yet he is not limited by it. He does not simply create music, nor does he offer listeners a musical space. He creates what Gilles Deleuze and Fe1ix Guattari （1987） call a line of becoming that passes between music making and a musical space. In 4 minutes and 33 seconds of silence, Cage presents a sense of emptiness and numbness felt simultaneously with fullness and explosion. In what appears to be stillness, the listener experiences the flux of movement; what appears to be devoid of depth, is filled with complexities. 433＂ embraces chance, uncertainty, and the unknown; it is an experimental process; it is becoming-music in 4 minutes and 33 seconds.
文摘It is well known that the ocular contour was characterized by its skin structure relevant to fillings of soft tissue and concave-convex bones. With aging, it changed a lot due to the volume loss of soft tissue. In recent studies, the aging process of the Asians whose eyelids flled with more soft tissue had signifcant impacts on the ocular contour. The aim of our work was to investigate the changes of the ocular contour of Asian people and establish a curve to describe it. In this study, it was demonstrated that the aging was not only linked to the distance between the inferior border of palpebral bag and the midpoint of palpebral fissure, but also correlated with the angle between palpebral fissure and the facial midline. Therefore, “Youthful Curve of Ocular Region” was established with measurements based on mentioned two areas. This curve went through the regions of upper and lower eyelid area and palpebral bags area. In addition, by using multivariate linear regression, a mathematical model to analyze this curve was obtained. The mathematical model was a crucial supplement to evaluate appearance age of ocular region in Asian people. Moreover, it had great potential in developments of anti-aging effects of eye cosmetics.
