Background The neutrophil-to-lymphocyte (N/L) ratio has been associated with poor prognosis in patients with heart failure, but it has not been compared with N-terminal pro-brain natriuretic peptide (NT-proBNP) in...Background The neutrophil-to-lymphocyte (N/L) ratio has been associated with poor prognosis in patients with heart failure, but it has not been compared with N-terminal pro-brain natriuretic peptide (NT-proBNP) in elderly patients with chronic heart failure (CHF). We sought to make this comparison. Methods A total of 1355 elderly patients with CHF were analyzed. A multivariate logistic regression model was used to analyze the variables associated with atrial fibrillation (AF). Cox regression analysis was used to assess the multivariable rela- tionship between the N/L ratio, NT-proBNP level, and subsequent major cardiovascular events (MCE). Results In the multiple logistic regression analysis, the N/L ratio was demonstrated as a risk factor for AF in elderly patients with CHF [odds ratio (OR): 1.079, 95% confi- dence interval (CI): 1.027-1.134, P = 0.003]. The median follow-up period was 18 months. In a multivariable model using tertiles of both variables, the highest tertile of the N/L ratio was significantly associated with MCE [hazard ratio (HR): 1.407, 95% CI: 1.098-1.802, P = 0.007] compared with the lowest tertile. Similarly, the highest NT-proBNP tertile was also significantly associated with MCE (HR: 1.461, 95% CI: 1.104-1.934, P- 0.008). Conclusions In elderly patients with CHF, the N/L ratio is one of the important risk factors for AF and it is an inexpensive and readily available marker with similar independent prognostic power to NT-proBNP. The risk of MCE increases 1.407-fold when the N/L ratio is elevated to the highest tertile.展开更多
Objective The predictive value of the metabolic syndrome (MetS) for mortality from all-cause and cardiovascular disease (CVD) in the Chinese population is unclear. The aim of this present study was to compare MetS...Objective The predictive value of the metabolic syndrome (MetS) for mortality from all-cause and cardiovascular disease (CVD) in the Chinese population is unclear. The aim of this present study was to compare MetS with its individual components as predictors of mortality in Chinese elderly adults. Methods A cohort of 1,535 subjects (994 men and 541 women) aged 50 years or older was selected from employees of a machinery factory in 1994 and followed until 2009. Cox models were used to estimate the hazard ratios (HRs) predicted by MetS according to the harmonized defmition and by its individual components. Results The baseline prevalence of MetS was 28.0% in men and 48.4% in women. During a median follow-up of 15 years, 414 deaths occurred, of these, 153 participants died from CVD. Adjusted for age and gender, the HRs of mortality from all-cause and CVD in participants with MetS were 1.47 (95% confidence interval (CI): 1.20-1.80) and 1.96 (95%CI: 1.42-2.72), respectively, compared with those without MetS. Non-significant higher risk of CVD mortality was seen in those with one or two individual components (HR = 1.22, 95%CI: 0.59-2.50; fir = 1.82, 95%CI: 0.91-3.64, respectively), while a substantially higher risk of CVD mortality only appeared in those with 3, 4, or 5 components (H_R = 2.81-3.72), compared with those with no components. On evaluating the MetS components individually, we found that, independent of MetS, only hypertension and impaired glucose predicted higher mortality. Conclusions The number of positive MetS components seems no more informative than classifying (dichotomous) MetS for CVD risks assessment in this Chinese cohort.展开更多
" A Lost Lady" is at beginning of the 20th century, a important work of creation of a famous American writer Willa Cather, through a story that a woman in a social swirl in old age gradually fall and sink, it reflec..." A Lost Lady" is at beginning of the 20th century, a important work of creation of a famous American writer Willa Cather, through a story that a woman in a social swirl in old age gradually fall and sink, it reflects the commercialization of human society and other traditional values and lifestyle impact and erosion, and the desire of mankind for a better civilization. Works use artistic symbolism to play a certain role in the development of the plot, the characters change shape and opposition figures to portray the psychological state.展开更多
Objective: To evaluate the value of CTS-guided percutaneous transthoracic biopsy for the diagnosis of pulmonary lesions in elder patients. Methods: The intact data of 78 elder patients underwent percutaneous pulmona...Objective: To evaluate the value of CTS-guided percutaneous transthoracic biopsy for the diagnosis of pulmonary lesions in elder patients. Methods: The intact data of 78 elder patients underwent percutaneous pulmonary biopsy with a spring-core biopsy needle under CTS guidance were analyzed. The diagnosis of all the cases was confirmed by pathology and follow-up. Results: Ninety-five lung biopsies were performed in 78 cases and satisfactory tissue specimens obtained in all cases, the success rate was 100%. The diagnosis for malignant tumors and benign lesions was 72 and 6, respectively. The overall accuracy rate was 100%. Pneumothorax was noted in 5 cases (6.4%) and hemoptysis seen in 10 patients (12.8%). Conclusion: CTS-guided percutaneous transthoracic biopsy with a spring-core biopsy needle are accurate, safe and quick for pulmonary lesions in elder patients.展开更多
Human capital depreciation can be divided into stock depreciation and utility depreciation, which will cause the waste of human capital investment, and let human capital value fail to fully embody, affecting social de...Human capital depreciation can be divided into stock depreciation and utility depreciation, which will cause the waste of human capital investment, and let human capital value fail to fully embody, affecting social development. In the critical time of China facing population aging and economic transformation, as the new human capital of the labor market, college students play an important role to social and economic development. Therefore, preventing and mitigating their human capital depreciation is necessary. This article focus on human capital investment and configuration stage, analyze the influence of unreasonable human capital investment system and separate labor market segmentation system to college student human capital depreciation, and put forword the corresponding countermeasures.展开更多
Predicting the lifetime of polymeric insulators is one of the most important research topics in studying the life cycle of high voltage insulators in the power transmission and distribution networks. HTV (high temper...Predicting the lifetime of polymeric insulators is one of the most important research topics in studying the life cycle of high voltage insulators in the power transmission and distribution networks. HTV (high temperature vulcanized) silicone rubber is a high performance dielectric material used within electrical power equipment, in particular transmission and distribution insulators. In this paper, we proposed a new approach using the Newton's method and Lagrange method to predict the aging of HTV silicone rubber that are subjected to multiple stress conditions. Concentration of chemical elements such as carbon, oxygen, silicon and aluminum were obtained and evaluated using a SEM (scanning electron microscope) with EDS (energy dispersive X-ray spectroscopy). Curve fitting using the Newton's and Lagrange interpolation methods yield useful linear interpolation equations that describe the aging characteristic of the specimens under study. This approach can be applied to predict the change in chemical concentration of polymeric insulators over the life cycle with good accuracy.展开更多
The value of social security funds, has always been an important part of our country social security enterprise as a whole, it is the one of the main ways to realize the social stability and national economic income. ...The value of social security funds, has always been an important part of our country social security enterprise as a whole, it is the one of the main ways to realize the social stability and national economic income. In the triple pressure with ageing population, inflation and social security transition, the value of the social security fund in our country is particularly acute. Analyses the receipts and expenditures of social security funds, investment and operation structure and put forward some rationalization proposal, which has significant meaning for a better play to the role of the social security fund and actively promote the innovation and development of China's social security fund management.展开更多
The aim of this study is to identify the variables affecting land value. Examined land was selected from the village in Vientiane capital city Laos. Data was collected from 100 villages in center of Vientiane capital ...The aim of this study is to identify the variables affecting land value. Examined land was selected from the village in Vientiane capital city Laos. Data was collected from 100 villages in center of Vientiane capital city by using survey methods. A hedonic price analysis was conducted to determine the marginal return to different land characteristics using an econometric model corrected for correlation. Parcel characteristics such as distance to public park, village income, distance of population, number of the school within 500 meters buffer, distance to the temple, distance to the major market and distance to the business center (CBD). Arc GIS 9.2 was applied to calculate the distance of the factors, after that SPSS 15.0 was used to calculate the land price characteristic based on hedonic price model. The results showed that the distance to the center of population was the main factor influencing to the land price, and followed by school and village income. Map of the land price before and after hedonic price analysis were produced. The land price valuation approaches based on hedonic price model for Vientiane capital city were developed and land price map were predicted. Hedonic price model and GIS were very useful for this research, and finally the policy of the land valuation based on GIS was developed.展开更多
This article through to new embedded geriatric rehabilitation care development present situation, pointed out that in the popularization of its restriction factors, and then asked a further analysis of various factors...This article through to new embedded geriatric rehabilitation care development present situation, pointed out that in the popularization of its restriction factors, and then asked a further analysis of various factors, constructed the obstacle factors explanation structure model (ISM).According to the result of classification model and find out the problem, the most direct factors and put forward the corresponding Suggestions, facilities for embedded geriatric rehabilitation nursing mode to find out the key points of development, provide a reference value to scientific basis.展开更多
Many patients with diabetes are not diagnosed at all or are diagnosed too late to be effectively treated, resulting in nonspecific symptoms and a long period of incubation of the disease. Pre-diabetes is an early warn...Many patients with diabetes are not diagnosed at all or are diagnosed too late to be effectively treated, resulting in nonspecific symptoms and a long period of incubation of the disease. Pre-diabetes is an early warning signal of diabetes, and the change of urine glucose in this period has been ignored even though urine has long been related with diabetes. In this study, Zucker diabetic fatty (ZDF) rats were used to test if there were changes in urine glucose before blood glucose increases. Six 8-week-old male ZDF rats (fa/fa) and Zucker lean (ZL) rats (fa/+) were fed with Purina 5008 high-fat diet and tested for fasting blood glucose and urine glucose. After 12 weeks of feeding, the urine glucose values of the ZL rats were normal (0–10 mmol L^(-1)), but the values of the ZDF model rats increased 10 weeks before their blood glucose levels elevated. The urine glucose values of the ZDF model rats showed a state of disorder that was frequently elevated (>10 mmol L^(-1)) and occasionally normal (0–10 mmol L^(-1)). This finding may provide an easy early screening for diabetes by long-term monitoring of urine glucose levels: pre-diabetes may be revealed by frequently disordered urine glucose levels over a period.展开更多
Up to now the chirality is seldom studied in the diluted spin glass although many investigations have been performed on the site-ordered Edwards-Anderson model. By simulation, we investigate the dynamicaJ properties o...Up to now the chirality is seldom studied in the diluted spin glass although many investigations have been performed on the site-ordered Edwards-Anderson model. By simulation, we investigate the dynamicaJ properties of both the spin-glass and the chiral-glass phases in a diluted dipolar system, which was manifested to have a spin-glass transition by recent numerical study. By scaling we find that both phases have the same aging behavior and closer aging parameterμ. Similarly, the domains grow in the same way and both phases have a closer barrier exponent g2. It means that both the spins and the chirality have the same dynamical properties and they may freeze at the same temperature.展开更多
文摘Background The neutrophil-to-lymphocyte (N/L) ratio has been associated with poor prognosis in patients with heart failure, but it has not been compared with N-terminal pro-brain natriuretic peptide (NT-proBNP) in elderly patients with chronic heart failure (CHF). We sought to make this comparison. Methods A total of 1355 elderly patients with CHF were analyzed. A multivariate logistic regression model was used to analyze the variables associated with atrial fibrillation (AF). Cox regression analysis was used to assess the multivariable rela- tionship between the N/L ratio, NT-proBNP level, and subsequent major cardiovascular events (MCE). Results In the multiple logistic regression analysis, the N/L ratio was demonstrated as a risk factor for AF in elderly patients with CHF [odds ratio (OR): 1.079, 95% confi- dence interval (CI): 1.027-1.134, P = 0.003]. The median follow-up period was 18 months. In a multivariable model using tertiles of both variables, the highest tertile of the N/L ratio was significantly associated with MCE [hazard ratio (HR): 1.407, 95% CI: 1.098-1.802, P = 0.007] compared with the lowest tertile. Similarly, the highest NT-proBNP tertile was also significantly associated with MCE (HR: 1.461, 95% CI: 1.104-1.934, P- 0.008). Conclusions In elderly patients with CHF, the N/L ratio is one of the important risk factors for AF and it is an inexpensive and readily available marker with similar independent prognostic power to NT-proBNP. The risk of MCE increases 1.407-fold when the N/L ratio is elevated to the highest tertile.
基金This study was supported by the National Natural Science Foundation of China,Ministry of Science and Technology of China,National Department Public Benefit Research Foundation by Ministry of Health of China
文摘Objective The predictive value of the metabolic syndrome (MetS) for mortality from all-cause and cardiovascular disease (CVD) in the Chinese population is unclear. The aim of this present study was to compare MetS with its individual components as predictors of mortality in Chinese elderly adults. Methods A cohort of 1,535 subjects (994 men and 541 women) aged 50 years or older was selected from employees of a machinery factory in 1994 and followed until 2009. Cox models were used to estimate the hazard ratios (HRs) predicted by MetS according to the harmonized defmition and by its individual components. Results The baseline prevalence of MetS was 28.0% in men and 48.4% in women. During a median follow-up of 15 years, 414 deaths occurred, of these, 153 participants died from CVD. Adjusted for age and gender, the HRs of mortality from all-cause and CVD in participants with MetS were 1.47 (95% confidence interval (CI): 1.20-1.80) and 1.96 (95%CI: 1.42-2.72), respectively, compared with those without MetS. Non-significant higher risk of CVD mortality was seen in those with one or two individual components (HR = 1.22, 95%CI: 0.59-2.50; fir = 1.82, 95%CI: 0.91-3.64, respectively), while a substantially higher risk of CVD mortality only appeared in those with 3, 4, or 5 components (H_R = 2.81-3.72), compared with those with no components. On evaluating the MetS components individually, we found that, independent of MetS, only hypertension and impaired glucose predicted higher mortality. Conclusions The number of positive MetS components seems no more informative than classifying (dichotomous) MetS for CVD risks assessment in this Chinese cohort.
文摘" A Lost Lady" is at beginning of the 20th century, a important work of creation of a famous American writer Willa Cather, through a story that a woman in a social swirl in old age gradually fall and sink, it reflects the commercialization of human society and other traditional values and lifestyle impact and erosion, and the desire of mankind for a better civilization. Works use artistic symbolism to play a certain role in the development of the plot, the characters change shape and opposition figures to portray the psychological state.
文摘Objective: To evaluate the value of CTS-guided percutaneous transthoracic biopsy for the diagnosis of pulmonary lesions in elder patients. Methods: The intact data of 78 elder patients underwent percutaneous pulmonary biopsy with a spring-core biopsy needle under CTS guidance were analyzed. The diagnosis of all the cases was confirmed by pathology and follow-up. Results: Ninety-five lung biopsies were performed in 78 cases and satisfactory tissue specimens obtained in all cases, the success rate was 100%. The diagnosis for malignant tumors and benign lesions was 72 and 6, respectively. The overall accuracy rate was 100%. Pneumothorax was noted in 5 cases (6.4%) and hemoptysis seen in 10 patients (12.8%). Conclusion: CTS-guided percutaneous transthoracic biopsy with a spring-core biopsy needle are accurate, safe and quick for pulmonary lesions in elder patients.
文摘Human capital depreciation can be divided into stock depreciation and utility depreciation, which will cause the waste of human capital investment, and let human capital value fail to fully embody, affecting social development. In the critical time of China facing population aging and economic transformation, as the new human capital of the labor market, college students play an important role to social and economic development. Therefore, preventing and mitigating their human capital depreciation is necessary. This article focus on human capital investment and configuration stage, analyze the influence of unreasonable human capital investment system and separate labor market segmentation system to college student human capital depreciation, and put forword the corresponding countermeasures.
文摘Predicting the lifetime of polymeric insulators is one of the most important research topics in studying the life cycle of high voltage insulators in the power transmission and distribution networks. HTV (high temperature vulcanized) silicone rubber is a high performance dielectric material used within electrical power equipment, in particular transmission and distribution insulators. In this paper, we proposed a new approach using the Newton's method and Lagrange method to predict the aging of HTV silicone rubber that are subjected to multiple stress conditions. Concentration of chemical elements such as carbon, oxygen, silicon and aluminum were obtained and evaluated using a SEM (scanning electron microscope) with EDS (energy dispersive X-ray spectroscopy). Curve fitting using the Newton's and Lagrange interpolation methods yield useful linear interpolation equations that describe the aging characteristic of the specimens under study. This approach can be applied to predict the change in chemical concentration of polymeric insulators over the life cycle with good accuracy.
文摘The value of social security funds, has always been an important part of our country social security enterprise as a whole, it is the one of the main ways to realize the social stability and national economic income. In the triple pressure with ageing population, inflation and social security transition, the value of the social security fund in our country is particularly acute. Analyses the receipts and expenditures of social security funds, investment and operation structure and put forward some rationalization proposal, which has significant meaning for a better play to the role of the social security fund and actively promote the innovation and development of China's social security fund management.
文摘The aim of this study is to identify the variables affecting land value. Examined land was selected from the village in Vientiane capital city Laos. Data was collected from 100 villages in center of Vientiane capital city by using survey methods. A hedonic price analysis was conducted to determine the marginal return to different land characteristics using an econometric model corrected for correlation. Parcel characteristics such as distance to public park, village income, distance of population, number of the school within 500 meters buffer, distance to the temple, distance to the major market and distance to the business center (CBD). Arc GIS 9.2 was applied to calculate the distance of the factors, after that SPSS 15.0 was used to calculate the land price characteristic based on hedonic price model. The results showed that the distance to the center of population was the main factor influencing to the land price, and followed by school and village income. Map of the land price before and after hedonic price analysis were produced. The land price valuation approaches based on hedonic price model for Vientiane capital city were developed and land price map were predicted. Hedonic price model and GIS were very useful for this research, and finally the policy of the land valuation based on GIS was developed.
文摘This article through to new embedded geriatric rehabilitation care development present situation, pointed out that in the popularization of its restriction factors, and then asked a further analysis of various factors, constructed the obstacle factors explanation structure model (ISM).According to the result of classification model and find out the problem, the most direct factors and put forward the corresponding Suggestions, facilities for embedded geriatric rehabilitation nursing mode to find out the key points of development, provide a reference value to scientific basis.
基金supported by the National Key R&D Program of China (2016YFC1306300)the National Basic Research Program of China (2013CB530805)+3 种基金the Beijing Natural Science Foundation (7173264, 7172076)the Fundamental Research Funds for the Central Universities (2015KJJCB21)the Beijing cooperative construction project(110651103)Beijing Normal University (11100704)
文摘Many patients with diabetes are not diagnosed at all or are diagnosed too late to be effectively treated, resulting in nonspecific symptoms and a long period of incubation of the disease. Pre-diabetes is an early warning signal of diabetes, and the change of urine glucose in this period has been ignored even though urine has long been related with diabetes. In this study, Zucker diabetic fatty (ZDF) rats were used to test if there were changes in urine glucose before blood glucose increases. Six 8-week-old male ZDF rats (fa/fa) and Zucker lean (ZL) rats (fa/+) were fed with Purina 5008 high-fat diet and tested for fasting blood glucose and urine glucose. After 12 weeks of feeding, the urine glucose values of the ZL rats were normal (0–10 mmol L^(-1)), but the values of the ZDF model rats increased 10 weeks before their blood glucose levels elevated. The urine glucose values of the ZDF model rats showed a state of disorder that was frequently elevated (>10 mmol L^(-1)) and occasionally normal (0–10 mmol L^(-1)). This finding may provide an easy early screening for diabetes by long-term monitoring of urine glucose levels: pre-diabetes may be revealed by frequently disordered urine glucose levels over a period.
基金Supported by National Natural Science Foundation of China under Grant Nos.11247428,61274101Natural Science Foundation of Liaoning Province under Grant No.20121078
文摘Up to now the chirality is seldom studied in the diluted spin glass although many investigations have been performed on the site-ordered Edwards-Anderson model. By simulation, we investigate the dynamicaJ properties of both the spin-glass and the chiral-glass phases in a diluted dipolar system, which was manifested to have a spin-glass transition by recent numerical study. By scaling we find that both phases have the same aging behavior and closer aging parameterμ. Similarly, the domains grow in the same way and both phases have a closer barrier exponent g2. It means that both the spins and the chirality have the same dynamical properties and they may freeze at the same temperature.