Objective:Frailty is a common geriatric syndrome defined as multiple deficits,impairing the capacity to figure out insult.Previous studies have reported a significant association between frailty and mortality in strok...Objective:Frailty is a common geriatric syndrome defined as multiple deficits,impairing the capacity to figure out insult.Previous studies have reported a significant association between frailty and mortality in stroke patients.This study aimed to explore the association between frailty and mortality among older Chinese stroke patients.Methods:This study was a secondary analysis of a multicenter prospective cohort study conducted in older Chinese inpatients from October 2018 to February 2020,and patients with a primary diagnosis of stroke including hemorrhage and ischemia,were included in our study.Frailty of older inpatients with stroke from six hospitals was measured by the FRAIL scale,and a one-year follow-up was performed by well-trained nurses of these hospitals via telephone.Multivariable logistic regression was used to detect the association between frailty and one-year mortality.Results:A total of 530 stroke patients with an average age of 72.94(SD¼5.79)years were included in the present study.There were 37(7.0%)hemorrhagic strokes and 493(93.0%)ischemic strokes,with 228(43.0%)females in this population.The prevalence of frailty was 22.5%.In the logistic regression model with adjustment for age,sex,instrumental activities of daily living(IADL),basic activities of daily living(ADL),education,history of falls,BMI,smoking,alcohol consumption,low handgrip strength,type of stroke and polypharmacy,stroke patients with frailty had an increased risk of one-year mortality compared to those without frailty(OR¼3.38,95%CI:1.22e9.37,P¼0.019).Conclusion:Our study indicated that frailty was an independent risk factor for one-year all-cause mor-tality among older stroke patients in China.Frailty may be an essential factor for clinicians to consider before making a comprehensive treatment,and corresponding mixed interventions,including exercise training and nutritional programs,need to be conducted among older stroke patients.展开更多
Objective:To estimate the prevalence of dysphagia and frailty among hospitalized older patients and to analyze the relationship between dysphagia and frailty in these people.Methods:Data were collected on 386 particip...Objective:To estimate the prevalence of dysphagia and frailty among hospitalized older patients and to analyze the relationship between dysphagia and frailty in these people.Methods:Data were collected on 386 participants aged 65 and older in a general hospital from April to December 2017.Patients were asked to complete a self-designed demographic questionnaire.Frailty and swallowing function assessments were performed using the Fried frailty phenotype and the 30-ml water swallowing test,respectively.Multiple stepwise logistic regression analyses were used to identify the association between frailty and dysphagia.Results:Dysphagia developed in 31.1%of older people,and 24.4%developed frailty.Frailty was statistically significantly related with dysphagia.Dysphagia was more prevalent in frail and pre-frail patients(48.9%and 32.4%,respectively)than those who were non-frail(13.6%).In multivariate analyses,frail(OR,5.420;95%CI,2.684±10.944;P<0.001)and history of choking/coughing while drinking(OR,2.954;95%CI,1.844±4.733;P<0.001)were associated with dysphagia.result.Conclusions:Frailty is associated with dysphagia.More attention should be paid to frailty and dysphagia of the elderly and further studies are needed to evaluate the correlated mechanism and develop targeted nursing interventions.展开更多
基金Fundamental Research Funds for Central Universities of Peking Union Medical College(No.3332020007).
文摘Objective:Frailty is a common geriatric syndrome defined as multiple deficits,impairing the capacity to figure out insult.Previous studies have reported a significant association between frailty and mortality in stroke patients.This study aimed to explore the association between frailty and mortality among older Chinese stroke patients.Methods:This study was a secondary analysis of a multicenter prospective cohort study conducted in older Chinese inpatients from October 2018 to February 2020,and patients with a primary diagnosis of stroke including hemorrhage and ischemia,were included in our study.Frailty of older inpatients with stroke from six hospitals was measured by the FRAIL scale,and a one-year follow-up was performed by well-trained nurses of these hospitals via telephone.Multivariable logistic regression was used to detect the association between frailty and one-year mortality.Results:A total of 530 stroke patients with an average age of 72.94(SD¼5.79)years were included in the present study.There were 37(7.0%)hemorrhagic strokes and 493(93.0%)ischemic strokes,with 228(43.0%)females in this population.The prevalence of frailty was 22.5%.In the logistic regression model with adjustment for age,sex,instrumental activities of daily living(IADL),basic activities of daily living(ADL),education,history of falls,BMI,smoking,alcohol consumption,low handgrip strength,type of stroke and polypharmacy,stroke patients with frailty had an increased risk of one-year mortality compared to those without frailty(OR¼3.38,95%CI:1.22e9.37,P¼0.019).Conclusion:Our study indicated that frailty was an independent risk factor for one-year all-cause mor-tality among older stroke patients in China.Frailty may be an essential factor for clinicians to consider before making a comprehensive treatment,and corresponding mixed interventions,including exercise training and nutritional programs,need to be conducted among older stroke patients.
基金The data was collected from Peking Union Medical College Hospital.We wish to thank all those who generously agreed to be interviewed for our work.We also sincerely thank Dr.Carrie Tudor for her revision of this paper.
文摘Objective:To estimate the prevalence of dysphagia and frailty among hospitalized older patients and to analyze the relationship between dysphagia and frailty in these people.Methods:Data were collected on 386 participants aged 65 and older in a general hospital from April to December 2017.Patients were asked to complete a self-designed demographic questionnaire.Frailty and swallowing function assessments were performed using the Fried frailty phenotype and the 30-ml water swallowing test,respectively.Multiple stepwise logistic regression analyses were used to identify the association between frailty and dysphagia.Results:Dysphagia developed in 31.1%of older people,and 24.4%developed frailty.Frailty was statistically significantly related with dysphagia.Dysphagia was more prevalent in frail and pre-frail patients(48.9%and 32.4%,respectively)than those who were non-frail(13.6%).In multivariate analyses,frail(OR,5.420;95%CI,2.684±10.944;P<0.001)and history of choking/coughing while drinking(OR,2.954;95%CI,1.844±4.733;P<0.001)were associated with dysphagia.result.Conclusions:Frailty is associated with dysphagia.More attention should be paid to frailty and dysphagia of the elderly and further studies are needed to evaluate the correlated mechanism and develop targeted nursing interventions.
