Objective To determine the association between plasma brain natriuretic peptide (BNP) level in patients with heart failure (HF) and physical frailty as well as with each domain of physical frailty. Methods Two hun...Objective To determine the association between plasma brain natriuretic peptide (BNP) level in patients with heart failure (HF) and physical frailty as well as with each domain of physical frailty. Methods Two hundred and six outpatients of cardiovascular medicine aged 60 years and older who had been hospitalized for HF or had been given a prescription medication for HF were included. Physical frailty was assessed using the following five domains: slowness, weakness, exhaustion, low activity, and shrinking, according to the Cardiovascular Health Study. Patients were divided into nonfi-ailty and frailty groups according to frailty scores. Plasma BNP level was measured. The 6-min walk test was performed to measure endurance. Results Plasma BNP was significantly different between the two groups (frailty group: 158.0 i 214.7 pg/mL, nonfrailty group: 65.2 ~ 88.0 pg/mL, P 〈 0.01). Multivariate logistic regression analysis revealed log-transformed plasma BNP (Log BNP) was significantly associated with physical frailty (OR: 1.68, 95% CI: 1.11-2.56), and Log BNP was significantly associated with the slowness domain (walking speed 〈 1.0 m/s) of physical frailty (OR: 1.75, 95% Ch 1.15-2.67). Additionally, Log BNP was negatively correlated to the 6-minute walk distance (6MWD) (p=0.37, P 〈 0.01), while 6MWD was positively correlated to walking speed (p = 0.66, P 〈 0.01). Conclusions Plasma BNP level was related to physical frailty, especially in the slowness domain. Endurance may intervene in the associations between plasma BNP level and walking speed.展开更多
Objectives:To explore the acceptability and feasibility of public square dancing among community residents with mild cognitive impairment(MCI)and depressive symptoms.Methods:This mixed-method study consisted of a quan...Objectives:To explore the acceptability and feasibility of public square dancing among community residents with mild cognitive impairment(MCI)and depressive symptoms.Methods:This mixed-method study consisted of a quantitative and a qualitative phase.From January to July 2018,a total of 241 community-dwelling senior citizens who complained of memory loss in one community in the Haidian District in Beijing were approached and screened,and 41 qualified for the study.Among them,35 senior citizens participated in the public square dancing intervention.By the end of the three-month follow-up,31 senior citizens completed the whole study.The Subjective Exercise Experience Scale(SEES)was used to survey senior citizens at the end of the three-month public square dancing intervention and follow-up to measure the participants’subjective exercise experience.Then 15 senior citizens were interviewed to collect attitudes,opinions,and suggestions related to the intervention.Results:During the intervention,90.6%of senior citizens met the requirement for defined hours.All senior citizens continued to dance at the three-month follow-up,and 32.3%met the requirement for defined hours.The scores of psychological well-being(11.03±2.82 vs.14.87±3.93,P<0.001)and fatigue(11.00[8.00,12.00]vs.14.00[9.00,18.00],P<0.001)increased at the end of the three-month follow-up.Qualitative research results extracted four major themes:increased confidence and a sense of accomplishment;easy to learn,close to real life,and sense of belonging;promotes physical and mental health;future expectations include music selection,reduced weather disruption,and self-organizing workouts.Conclusion:Public square dancing proved to be an acceptable,viable,and valuable intervention for MCI residents with depressive symptoms,which could be carried out by nursing staff in the community.Future studies should consider the appropriate population,intensity,and frequency of public square dancing and its effect on specific cognitive functions.展开更多
文摘Objective To determine the association between plasma brain natriuretic peptide (BNP) level in patients with heart failure (HF) and physical frailty as well as with each domain of physical frailty. Methods Two hundred and six outpatients of cardiovascular medicine aged 60 years and older who had been hospitalized for HF or had been given a prescription medication for HF were included. Physical frailty was assessed using the following five domains: slowness, weakness, exhaustion, low activity, and shrinking, according to the Cardiovascular Health Study. Patients were divided into nonfi-ailty and frailty groups according to frailty scores. Plasma BNP level was measured. The 6-min walk test was performed to measure endurance. Results Plasma BNP was significantly different between the two groups (frailty group: 158.0 i 214.7 pg/mL, nonfrailty group: 65.2 ~ 88.0 pg/mL, P 〈 0.01). Multivariate logistic regression analysis revealed log-transformed plasma BNP (Log BNP) was significantly associated with physical frailty (OR: 1.68, 95% CI: 1.11-2.56), and Log BNP was significantly associated with the slowness domain (walking speed 〈 1.0 m/s) of physical frailty (OR: 1.75, 95% Ch 1.15-2.67). Additionally, Log BNP was negatively correlated to the 6-minute walk distance (6MWD) (p=0.37, P 〈 0.01), while 6MWD was positively correlated to walking speed (p = 0.66, P 〈 0.01). Conclusions Plasma BNP level was related to physical frailty, especially in the slowness domain. Endurance may intervene in the associations between plasma BNP level and walking speed.
文摘Objectives:To explore the acceptability and feasibility of public square dancing among community residents with mild cognitive impairment(MCI)and depressive symptoms.Methods:This mixed-method study consisted of a quantitative and a qualitative phase.From January to July 2018,a total of 241 community-dwelling senior citizens who complained of memory loss in one community in the Haidian District in Beijing were approached and screened,and 41 qualified for the study.Among them,35 senior citizens participated in the public square dancing intervention.By the end of the three-month follow-up,31 senior citizens completed the whole study.The Subjective Exercise Experience Scale(SEES)was used to survey senior citizens at the end of the three-month public square dancing intervention and follow-up to measure the participants’subjective exercise experience.Then 15 senior citizens were interviewed to collect attitudes,opinions,and suggestions related to the intervention.Results:During the intervention,90.6%of senior citizens met the requirement for defined hours.All senior citizens continued to dance at the three-month follow-up,and 32.3%met the requirement for defined hours.The scores of psychological well-being(11.03±2.82 vs.14.87±3.93,P<0.001)and fatigue(11.00[8.00,12.00]vs.14.00[9.00,18.00],P<0.001)increased at the end of the three-month follow-up.Qualitative research results extracted four major themes:increased confidence and a sense of accomplishment;easy to learn,close to real life,and sense of belonging;promotes physical and mental health;future expectations include music selection,reduced weather disruption,and self-organizing workouts.Conclusion:Public square dancing proved to be an acceptable,viable,and valuable intervention for MCI residents with depressive symptoms,which could be carried out by nursing staff in the community.Future studies should consider the appropriate population,intensity,and frequency of public square dancing and its effect on specific cognitive functions.